Comparative study of cerebellar degeneration in canine neuroaxonal dystrophy, cerebellar cortical abiotrophy, and neuronal ceroid-lipofuscinosis

Journal of Veterinary Medical Science

Volumn 72, Issue 11, 2010, Pages 1495-1499

  Nibe, Kazumi ^a   Nakayama, Hiroyuki ^b   Uchida, Kazuyuki ^b  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Canine; Cerebellar cortical abiotrophy; Cerebellar degeneration; Ceroid lipofuscinosis; Neuroaxonal dystrophy

Indexed keywords

CASPASE 3;

ANIMAL; ANIMAL DISEASE; CEREBELLUM; CEREBELLUM CORTEX; DOG; DOG DISEASE; ENZYMOLOGY; FEMALE; MALE; METABOLISM; MORTALITY; NEUROAXONAL DYSTROPHY; NEURONAL CEROID LIPOFUSCINOSIS; NOTE; ORCHIECTOMY; PATHOLOGY; PURKINJE CELL; SPINOCEREBELLAR DEGENERATION;

ANIMALS; CASPASE 3; CEREBELLAR CORTEX; CEREBELLUM; DOG DISEASES; DOGS; FEMALE; MALE; NEUROAXONAL DYSTROPHIES; NEURONAL CEROID-LIPOFUSCINOSES; ORCHIECTOMY; PURKINJE CELLS; SPINOCEREBELLAR DEGENERATIONS;

CANIS FAMILIARIS;

EID: 78649780366     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.10-0072     Document Type: Note

References (36)

1. Anzai, Y., Hayashi, M., Fueki, N., Kurata, K. and Ohya, T. 2006. Protracted juvenile neuronal ceroid lipofuscinosis-an autopsy report and immunohistochemical analysis. Brain Development. 28: 462-465.
2. Balsinde, J. and Balboa, M.A. 2005. Cellular regulation and proposed biological functions of group VIA calcium-independent phospholipase A2 in activated cells. Cell. Signaling 17: 1052-1062.
3. Biancheri, R., Rossi, A., Alpigiani, G., Filocamo, M., Gan-dolfo, C., Lorini, R. and Minetti, C. 2007. Cerebellar atrophy without cerebellar cortex hyperintensity in infantile neuroax-onal dystrophy (INAD) due to PLA2G6 mutation. Eur. J. Pae-diatr. Neurol. 11: 175-177.
4. Chrisman, C.L., Cork, L.C. and Gamble, D.A. 1984. Neuroax-onal dystrophy of Rottweiler dogs. J. Am. Vet. Med. Assoc. 184: 464-467.
5. deLahunta, A. 1990. Abiotrophy in domestic animals: review. Can. J. Vet. Res. 54: 65-76.
6. Dueñas, A.M., Goold, R. and Giunti, P. 2006. Molecular pathogenesis of spinocerebellar ataxias. Brain 129: 1357-1370.
7. Evans, M.G., Mullaney, T.P. and Lowrie, C.T. 1988. Neuroax-onal dystrophy in a rottweiler pup. J. Am. Vet. Med. Assoc. 192: 1560-1562.
8. Flegel, T., Matiasek, K., Henke, D. and Grevel, V. 2007. Cere-bellar cortical degeneration with selective granule cell loss in Bavarian mountain dogs. J. Small Anim. Pract. 48: 462-465.
9. Franklin, R.J., Jeffery, N.D. and Ramsey, I.K. 1995. Neuroax-onal dystrophy in a litter of papillon pups. J. Small Anim. Pract. 36: 441-444.
10. Franks, J.N., Dewey, C.W., Walker, M.A. and Storts, R.W. 1999. Computed tomographic findings of ceroid lipofuscinosis in a dog. J. Am. Vet. Med. Assoc. 35: 430-435.
11. Gordon, N. 2002. Pantothenate kinase-associated neurodegen-eration (Hallervorden-Spatz syndrome). Eur. J. Paediatr. Neu-rol. 6: 243-247.
12. Hachiya, Y., Hayashi, M., Kumada, S., Uchiyama, A., Tsuchiya, K. and Kurata, K. 2006. Mechanisms of neurodegen-eration in neuronal ceroid-lipofuscinoses. Acta Neuropathol. 111: 168-177.
13. Hayflick, S.J. 2003. Pantothenate kinase-associated neurode-generation (formerly Hallervorden-Spatz syndrome). J. Neu-rol. Sci. 207: 106-107.
14. Jolly, R.D. and Walkley, S.U. 1997. Lysosomal storage diseases of animals: an essay in comparative pathology. Vet. Pathol. 34: 527-548.
15. Katz, M.L., Khan, S., Awano, T., Shahid, S.A., Siakotos, A.N. and Johnson, G.S. 2005. A mutation in the CLN8 gene in English Setter dogs with neuronal ceroid-lipofuscinosis. Bio-chem. Biophys. Res. Commun. 327: 541-517.
16. Khateeb, S., Flusser, H., Ofir, R., Shelef, I., Narkis, G., Vardi, G., Shorer, Z., Levy, R., Galil, A., Elbedour, K. and Birk, O.S. 2006. PLA2G6 mutation underlies infantile neuroaxonal dystrophy. Am. J. Hum. Genet. 79: 942-948.
17. Kuo, Y.M., Duncan, J.L., Westaway, S.K., Yang, H., Nune, G., Xu, E.Y., Hayflick, S.J. and Gitschier, J. 2005. Deficiency of pantothenate kinase 2 (Pank2) in mice leads to retinal degeneration and azoospermia. Hum. Mol. Genet. 14: 49-57.
18. Lane, S.C., Jolly, R.D., Schmechel, D.E., Alroy, J. and Boust-any, R.M. 1996. Apoptosis as the mechanism of neurodegener-ation in Batten's disease. J. Neurochem. 67: 677-683.
19. Leonardi, R., Zhang, Y.M., Lykidis, A., Rock, C.O. and Jack-owski, S. 2007. Localization and regulation of mouse pantoth-enate kinase 2. FEBS Letters. 581: 4639-4644.
20. Malik, I., Turk, J., Mancuso, D.J., Montier, L., Wohltmann, M., Wozniak, D.F., Schmidt, R.E., Gross, R.W. and Kotzbauer, P.T. 2008. Disrupted membrane homeostasis and accumulation of ubiquitinated proteins in a mouse model of infantile neu-roaxonal dystrophy caused by PLA2G6 mutations. Am. J. Pathol. 172: 406-416.
21. Melville, S.A., Wilson, C.L., Chiang, C.S., Studdert, V.P., Lin-gaas, F. and Wilton, A.N. 2005. A mutation in canine CLN5 causes neuronal ceroid lipofuscinosis in Border collie dogs. Genomics 86: 287-294.
22. Nakamoto, Y., Yamato, O., Uchida, K., Nibe, K., Tamura, S., Ozawa, T., Veoka, S., Nakaya, A., Yabuki, A. and Nakaichi, M. Neuronal ceroid-lipofuscinosis in long haired Chihuahas: Clinical, Pathological and Magnetic resonance imaging findings. J. Am. Anim. Hosp. Assoc. (In press).
23. Nibe, K., Kita, C., Morozumi, M., Awamura, Y., Tamura, S., Okuno, S., Kobayashi, T. and Uchida, K. 2007. Clinicopatho-logical features of canine neuroaxonal dystrophy and cerebellar cortical abiotrophy in Papillon and Papillon-related dogs. J. Vet. Med. Sci. 69: 1047-1052.
24. Nibe, K., Nakayama, H. and Uchida, K. 2009. Immunohis-tochemical features of dystrophic axons in Papillon dogs with neuroaxonal dystrophy. Vet. Pathol. 46: 474-483.
25. Persaud-Sawin, D.A. and Boustany, R.M. 2005. Cell death pathways in juvenile Batten disease. Apoptosis 10: 973-985.
26. Sacre, B.J., Cummings, J.F. and deLahunta, A. 1993. Neuroax-onal dystrophy in a Jack Russell terrier pup resembling human infantile neuroaxonal dystrophy. Cornell Vet. 83: 133-142.
27. Sandy, J.R., Slocombe, R.E., Mitten, R.W. and Jedwab, D. 2002. Cerebellar abiotrophy in a family of Border Collie dogs. Vet. Pathol. 39: 736-738.
28. Settembre, C., Fraldi, A., Rubinsztein, D.C. and Ballabio, A. 2008. Lysosomal storage diseases as disorders of autophagy. Autophagy 4: 113-114.
29. Shinzawa, K., Sumi, H., Ikawa, M., Matsuoka, Y., Okabe, M., Sakoda, S. and Tsujimoto, Y. 2008. Neuroaxonal dystrophy caused by group VIA phospholipase A2 deficiency in mice: a model of human neurodegenerative disease. J. Neurosci. 28: 2212-2220.
30. Six, D.A. and Dennis, E.A. 2000. The expanding superfamily of phospholipase A(2) enzymes: classification and characterization. Biochim. Biophys. Acta 1488: 1-19.
31. Summers, B.A., Cummings, J.F. and de Lahunta, A. 1995. Degenerative disease of the central nervous system. pp. 208-350. In: Veterinary Neuropathology (Summers, B.A., Cum-mings, J.F. and de Lahunta, A. eds.), Mosby-Year Book, St. Louis.
32. Tamura, S., Tamura, Y. and Uchida, K. 2007. Magnetic resonance imaging findings of neuroaxonal dystrophy in a papillon puppy. J. Small Anim. Pract. 48: 458-461.
33. Zhong, N. 2000. Neuronal ceroid lipofuscinoses and possible pathogenic mechanism. Mol. Genet. Metab. 71: 195-206.
34. Ross, C.A. 2002. Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders. Neuron 35: 819-822.
35. Kiselyov, K., Jennigs, J.J. Jr., Rbaibi, Y. and Chu, C.T. 2007. Autophagy, mitochondria and cell death in lysosomal storage diseases. Autophagy 3: 259-262.
36. Settembre, C., Fraldi, A., Rubinsztein, D.C. and Ballabio, A. 2008. Lysosomal storage diseases as disorders of autophagy. Autophagy 4: 113-114.