Clinicopathological features of canine neuroaxonal dystrophy and cerebellar cortical abiotrophy in papillon and papillon-related dogs

Journal of Veterinary Medical Science

Volumn 69, Issue 10, 2007, Pages 1047-1052

  Nibe, Kazumi ^a   Kita, Chiaki ^a   Morozumi, Motoji ^b   Awamura, Yuichi ^c   Tamura, Shinji ^d   Okuno, Seiichi ^e   Kobayashi, Takayuki ^e   Uchida, Kazuyuki ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b Togasaki Animal Hospital   (Japan)

^c Totsuka Animal Hospital   (Japan)

^d Tamura Animal Clinic   (Japan)

^e Animal Clinic Kobayashi   (Japan)

Author keywords

Canine; Cerebellar abiotrophy; Neuroaxonal dystrophy; Papillon; Spheroid

Indexed keywords

ANIMAL; ANIMAL DISEASE; ARTICLE; CASE REPORT; CEREBELLUM DISEASE; DOG; DOG DISEASE; FEMALE; GENETIC PREDISPOSITION; GENETICS; MALE; NEUROAXONAL DYSTROPHY; PATHOLOGY;

ANIMALS; CEREBELLAR DISEASES; DOG DISEASES; DOGS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; MALE; NEUROAXONAL DYSTROPHIES;

CANIS FAMILIARIS;

EID: 36248996532     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.69.1047     Document Type: Article

References (27)

1. Berry, M.L. and Blas-Machado, U. 2003. Cerebellar abiotrophy in a miniature schnauzer. Can. Vet. J. 44: 657-659.
2. Blakemore, W.F. and Palmer, A.C. 1985. Nervous disease in the chihuahua characterized by axonal swellings. Vet. Rec. 117: 498-499.
3. Bouley, D.M., McIntire, J.J., Harris, B.T., Tolwani, R.J., Otto, G.M., DeKruyff, R.H. and Hayflick, S.J. 2006. Spontaneous murine neuroaxonal dystrophy: a model of infantile neuroaxonal dystrophy. J. Comp. Pathol. 134: 161-170.
4. Carmichael, K.P., Howerth, E.W., Oliver, J.E. Jr. and Klappenbach, K.J. 1993 Neuroaxonal dystrophy in a group of related cats. J. Vet. Diagn. Invest. 5: 585-590.
5. Chrisman, C.L., Cork, L.C. and Gamble, D.A. 1984. Neuroaxonal dystrophy of Rottweiler dogs. J. Am. Vet. Med. Assoc. 184: 464-467.
6. Clark, R.G., Hartley, W.J., Burgess, G.S., Cameron, J.S. and Mitchell, G. 1982. Suspected inherited cerebellar neuroaxonal dystrophy in collie sheep dogs. N.Z. Vet. J. 30: 102-103.
7. de Lahunta, A. 1990. Abiotrophy in domestic animals: review. Can. J. Vet. Res. 54: 65-76.
8. Evans, M.G., Mullaney, T.P. and Lowrie, C.T. 1988. Neuroaxonal dystrophy in a rottweiler pup. J. Am. Vet. Med. Assoc. 192: 1560-1562.
9. Franklin, R.J., Jeffery, N.D. and Ramsey, I.K. 1995. Neuroax-onal dystrophy in a litter of papillon pups. J. Small Anim. Pract. 36: 441-444.
10. Gazulla, J. and Tintore, M.A. 2007. The P/Q-type voltagedependent calcium channel as pharmacological target in spinocerebellar ataxia type 6: gabapentin and pregabalin may be of therapeutic benefit. Med. Hypotheses 68: 131-136.
11. Gordon, N. 2002. Pantothenate kinase-associated neurodegeneration (Hallervorden-Spatz syndrome). Eur. J. Paediatr. Neurol. 6: 243-247.
12. Hayflick, S.J. 2003. Pantothenate kinase-associated neurodegeneration (formerly Hallervorden-Spatz syndrome). J. Neurol. Sci. 207: 106-107.
13. Jolly, R.D. and Walkley, S.U. 1997. Lysosomal storage diseases of animals: an essay in comparative pathology. Vet. Pathol. 34: 527-548.
14. Koeppen, A.H. 2005. The pathogenesis of spinocerebellar ataxia. Cerebellum 4: 62-73.
15. Koeppen, A.H. and Dickson, A.C. 2001. Iron in the Hallervorden-Spatz syndrome. Pediatr. Neurol. 25: 148-155.
16. 2+ channel alpha1A subunits translocate to nuclei and promote polyglutamine-mediated toxicity. Hum. Mol. Genet. 15: 1587-1599.
17. Kyllerman, M., Mansson, J.E., Lichtenstein, M., Percy, A.K. and Nordborg, C. 2001. Distal infantile neuroaxonal dystrophy-a new familial variant with perineuronal argyrophilic bodies. Acta Neuropathol. (Berl.) 102: 83-88.
18. McLellan, G.J., Cappello, R., Mayhew, I.G., Elks, R., Lybaert, P., Watte, C. and Bedford, P.G. 2003. Clinical and pathological observations in English cocker spaniels with primary metabolic vitamin E deficiency and retinal pigment epithelial dystrophy. Vet. Rec. 153: 287-292.
19. Muller, G., Alldinger, S., Moritz, A., Zurbriggen, A., Kirchhof, N., Sewell, A. and Baumgartner, W. 2001. GM1-gangliosidosis in Alaskan huskies: clinical and pathologic findings. Vet. Pathol. 38: 281-290.
20. Resibois, A. and Poncelet, L. 2004. Purkinje cell neuroaxonal dystrophy similar to nervous mutant mice phenotype in two sibling kittens. Acta Neuropathol. (Berl.) 107: 553-558.
21. Rodriguez, F., Espinosa de los Monteros, A., Morales, M., Herraez, P., Jaber, J.R. and Fernandez, A. 1996. Neuroaxonal dystrophy in two siamese kitten littermates. Vet. Rec. 138: 548-549.
22. Sacre, B.J., Cummings, J.F. and de Lahunta, A. 1993. Neuroaxonal dystrophy in a Jack Russell terrier pup resembling human infantile neuroaxonal dystrophy. Cornell Vet. 83: 133-142.
23. Sandy, J.R., Slocombe, R.E., Mitten, R.W. and Jedwab, D. 2002. Cerebellar abiotrophy in a family of Border Collie dogs. Vet. Pathol. 39: 736-738.
24. Siso, S., Ferrer, I. and Pumarola, M. Juvenile neuroaxonal dystrophy in a Rottweiler: accumulation of synaptic proteins in dystrophic axons. 2001. Acta Neuropathol. (Berl.) 102: 501-504.
25. Summers, B.A., Cummings, J.F. and de Lahunta, A. 1995. Degenerative disease of the central nervous system. pp. 208-350. In: Veterinary Neuropathology (Summers, B.A., Cummings, J.F. and de Lahunta, A. eds.), Mosby-Year Book, St. Louis.
26. 2+ channel alpha1A subunit gene and exhibits absence seizures. Brain Res. 1133: 168-177.
27. Takeuchi, I.K., Aoki, E. and Takeuchi, Y.K. 1994. Age-related and region-specific increase in number of concentric lamellar bodies in axon terminals and presynaptic axons in central nervous system of groggy mutant rat. Acta Neuropathol (Berl). 87: 628-634.