NAADP as an intracellular messenger regulating lysosomal calcium-release channels

Biochemical Society Transactions

Volumn 38, Issue 6, 2010, Pages 1424-1431

  Galione, Antony ^a   Morgan, Anthony J ^a   Arredouani, Abdelilah ^a   Davis, Lianne C ^a   Rietdorf, Katja ^a   Ruas, Margarida ^a   Parrington, John ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Calcium release channel; Endolysosomal system; Lysosome; Nicotinic acid adenine dinucleotide phosphate (NAADP); Two pore channel (TPC)

Indexed keywords

ANGIOTENSIN 2 RECEPTOR; CALCIUM CHANNEL; CALCIUM ION; CD38 ANTIGEN; CYCLIC ADENOSINE DIPHOSPHATE RIBOSE; ENDOTHELIN 1; FAS LIGAND; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; GLUTAMIC ACID; HISTAMINE; INSULIN; INTERLEUKIN 8; ISOPRENALINE; NICOTINIC ACID ADENINE DINUCLEOTIDE PHOSPHATE; NORADRENALIN; OXYTOCIN; THROMBIN;

CALCIUM TRANSPORT; CONFERENCE PAPER; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; ENDOSOME; HUMAN; HYPOXIA; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CALCIUM SIGNALING; ENDOSOMES; LYSOSOMES; NADP;

EID: 78649721315     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0381424     Document Type: Conference Paper

References (81)

1. 2+ from acidic stores. Biochem. Soc. Trans. 34, 922-926
2. Calcraft, P.J., Ruas, M., Pan, Z., Cheng, X., Arredouani, A., Hao, X., Tang, J., Rietdorf, K., Teboul, L., Chuang, K.T. et al. (2009) NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature 459, 596-600
3. 2+ from reserve granules, lysosome-related organelles, in sea urchin eggs. Cell 111, 703-708
4. Naylor, E., Arredouani, A., Vasudevan, S.R., Lewis, A.M., Parkesh, R., Mizote, A., Rosen, D., Thomas, J.M., Izumi, M., Ganesan, A. et al. (2009) Identification of a chemical probe for NAADP by virtual screening. Nat. Chem. Biol. 5, 220-226
5. Rosen, D., Lewis, A.M., Mizote, A., Thomas, J.M., Aley, P.K., Vasudevan, S.R., Parkesh, R., Galione, A., Izumi, M., Ganesan, A. and Churchill, G.C. (2009) Analogues of the nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist Ned-19 indicate two binding sites on the NAADP receptor. J. Biol. Chem. 284, 34930-34934
6. 2+ release channels. Pflügers Arch. 458, 869-876
7. Clapper, D.L., Walseth, T.F., Dargie, P.J. and Lee, H.C. (1987) Pyridine nucleotide metabolites stimulate calcium release from sea urchin egg microsomes desensitized to inositol trisphosphate. J. Biol. Chem. 262, 9561-9568
8. Epel, D., Patton, C., Wallace, R.W. and Cheung, W.Y. (1981) Calmodulin activates NAD kinase of sea urchin eggs: an early event of fertilization. Cell 23, 543-549 (Pubitemid 11096348)
9. 2+ mobilizing activities of cyclic ADP-ribose and inositol trisphosphate. Cell Regul. 1, 279-290
10. 2+ release in sea urchin egg homogenates: modulation by cyclic ADP-ribose. Science 253, 1143-1146
11. Lee, H.C. and Aarhus, R. (1995) A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-ribose. J. Biol. Chem. 270, 2152-2157
12. Lee, H.C. (1997) Mechanisms of calcium signaling by cyclic ADP-ribose and NAADP. Physiol. Rev. 77, 1133-1164
13. Lee, H.C. (2003) Calcium signaling: NAADP ascends as a new messenger. Curr. Biol. 13, R186-R188
14. 2+ releasing messengers. EMBO J. 21, 909-919
15. 2+ spiking in mouse pancreatic acinar cells. Curr. Biol. 15, 874-878
16. Aley, P.K., Noh, H.J., Gao, X., Tica, A.A., Brailoiu, E. and Churchill, G.C. (2010) A functional role for nicotinic acid adenine dinucleotide phosphate (NAADP) in oxytocin-mediated contraction of uterine smooth muscle from rat. J. Pharmacol. Exp. Ther. 333, 726-735
17. Aarhus, R., Graeff, R.M., Dickey, D.M., Walseth, T.F. and Lee, H.C. (1995) ADP-ribosyl cyclase and CD38 catalyze the synthesis of a calcium-mobilizing metabolite from NADP. J. Biol. Chem. 270, 30327-30333
18. 2+ signal that is essential for insulin secretion in mouse pancreatic islets. Diabetes 57, 868-878
19. 2+ signaling occurs via second messenger release from intraorganelle synthesis sites. Curr. Biol. 18, 1612-1618
20. 2+ signaling contributes to angiotensin II-induced activation of hepatic stellate cells: attenuation of hepatic fibrosis by CD38 ablation. J. Biol. Chem. 285, 576-582
21. 2+ release response to Fas activation in coronary arterial myocytes through NAADP: evidence from CD38 gene knockouts. Am. J. Physiol. Cell Physiol. 298, C1209-C1216
22. 2+ signaling in interleukin-8-treated lymphokine-activated killer cells. J. Biol. Chem. 285, 21877-21887
23. 2+ from a thapsigargin-insensitive pool. Biochem. J. 315, 721-725
24. 2+ stores. EMBO J. 20, 2666-2671
25. Lee, H.C. and Aarhus, R. (2000) Functional visualization of the separate but interacting calcium stores sensitive to NAADP and cyclic ADP-ribose. J. Cell Sci. 113, 4413-4420
26. 2+ signaling. Trends Cell Biol. 20, 277-286
27. Ramos, I.B., Miranda, K., Pace, D.A., Verbist, K.C., Lin, F.Y., Zhang, Y., Oldfield, E., Machado, E.A., de Souza, W. and Docampo, R. (2010) Calcium and polyphosphate-containing acidic granules of sea urchin eggs are similar to acidocalcisomes but are not the targets for NAADP. Biochem. J. 429, 485-495
28. 2+ stores. Biochem. J. 402, 301-310
29. 2+ release from insulin-containing vesicles in living pancreatic β-cells (MIN6). J. Biol. Chem. 278, 11057-11064
30. 2+ signals in pancreatic acinar and β cells. J. Biol. Chem 279, 7234-7240
31. Kinnear, N.P., Boittin, F.X., Thomas, J.M., Galione, A. and Evans, A.M. (2004) Lysosome-sarcoplasmic reticulum junctions: a trigger zone for calcium signaling by nicotinic acid adenine dinucleotide phosphate and endothelin-1. J. Biol. Chem. 279, 54319-54326
32. 2+ release from both the endoplasmic reticulum and acidic intracellular calcium stores through activation of inositol trisphosphate receptors and ryanodine receptors. J. Biol. Chem. 281, 40154-40163
33. 2+ stores and endocytosis by differential coupling to messengers. Curr. Biol. 16, 1931-1937
34. 2+ mobilization associated with lysosomes in coronary arterial myocytes. Am. J. Physiol. Heart Circ. Physiol. 291, H274-H282
35. 2+ stores in the heart. J. Biol. Chem. 282, 15302-15311
36. 2+ signaling in response to endothelin is via the receptor subtype B and requires the integrity of lipid rafts/caveolae. J. Cell. Physiol. 216, 396-404
37. Jardin, I., Lopez, J.J., Pariente, J.A., Salido, G.M. and Rosado, J.A. (2008) Intracellular calcium release from human platelets: different messengers for multiple stores. Trends Cardiovasc. Med 18, 57-61 (Pubitemid 351282494)
38. Lloyd-Evans, E., Morgan, A.J., He, X., Smith, D.A., Elliot-Smith, E., Sillence, D.J., Churchill, G.C., Schuchman, E.H., Galione, A. and Platt, F.M. (2008) Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium. Nat. Med. 14, 1247-1255
39. Thai, T.L., Churchill, G.C. and Arendshorst, W.J. (2009) NAADP receptors mediate calcium signaling stimulated by endothelin-1 and norepinephrine in renal afferent arterioles. Am. J. Physiol. Renal Physiol. 297, F510-F516
40. Brailoiu, G.C., Brailoiu, E., Parkesh, R., Galione, A., Churchill, G.C., Patel, S. and Dun, N.J. (2009) NAADP-mediated channel 'chatter' in neurons of the rat medulla oblongata. Biochem. J. 419, 91-97
41. 2+ stores by glutamate. Biochem. J. 422, 503-512
42. 2+-signalling upon lysosome proliferation. J. Biol. Chem. 285, 13321-13325
43. 2+-signalling patterns by NAADP in pancreatic acinar cells. Nature 398, 74-76
44. 2+ signalling by NAADP. Trends Biochem. Sci. 26, 482-489
45. 2+ trigger. Sci. Signaling 1, re10
46. 2+ signaling in T-lymphocytes. J. Biol. Chem. 280, 21394-21399
47. 2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist. Proc. Natl. Acad. Sci. U.S.A. 106, 10678-10683
48. 2+ signaling and endo-lysosomal trafficking. Curr. Biol. 20, 703-709
49. Galione, A. and Petersen, O.H. (2005) The NAADP receptor: new receptors or new regulation? Mol. Interv. 5, 73-79 (Pubitemid 40590506)
50. Ishibashi, K., Suzuki, M. and Imai, M. (2000) Molecular cloning of a novel form (two-repeat) protein related to voltage-gated sodium and calcium channels. Biochem. Biophys. Res. Commun. 270, 370-376
51. 2+ flux in Arabidopsis leaf cells. Plant Cell Physiol. 42, 900-905
52. 2+ -activated channel TPC1 regulates germination and stomatal movement. Nature 434, 404-408
53. Casey, T.M., Meade, J.L. and Hewitt, E.W. (2007) Organelle proteomics: identification of the exocytic machinery associated with the natural killer cell secretory lysosome. Mol. Cell. Proteomics 6, 767-780
54. 2+ -release from lysosomal stores. Pflügers Arch. 458, 891-899
55. Brailoiu, E., Churamani, D., Cai, X., Schrlau, M.G., Brailoiu, G.C., Gao, X., Hooper, R., Boulware, M.J., Dun, N.J., Marchant, J.S. and Patel, S. (2009) Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling. J Cell Biol. 186, 201-209
56. Durlu-Kandilci, N.T., Ruas, M., Cheng, K.T., Brading, A., Parrington, J. and Galione, A. (2010) TPC2 proteins mediate NAADP and agonist-evoked contractions of smooth muscle. J. Biol. Chem. 285, 24925-24932
57. 2+ currents in isolated lysosomes. J. Biol. Chem. 285, 21219-21222
58. 2+ is a major sensitiser of two-pore channels to NAADP. Biophys. J. 98, 682a-683a
59. Christensen, K.A., Myers, J.T. and Swanson, J.A. (2002) pH-dependent regulation of lysosomal calcium in macrophages. J. Cell Sci. 115, 599-607
60. Dong, X.P., Wang, X. and Xu, H. (2010) TRP channels of intracellular membranes. J. Neurochem. 113, 313-328
61. Qureshi, O.S., Paramasivam, A., Yu, J.C. and Murrell-Lagnado, R.D. (2007) Regulation of P2x4 receptors by lysosomal targeting, glycan protection and exocytosis. J. Cell Sci. 120, 3838-3849
62. 2+-release channel in β cells. Sci. Signaling 2, ra23
63. Beck, A., Kolisek, M., Bagley, L.A., Fleig, A. and Penner, R. (2006) Nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose regulate TRPM2 channels in T lymphocytes. FASEB J. 20, 962-964
64. Pryor, P.R., Reimann, F., Gribble, F.M. and Luzio, J.P. (2006) Mucolipin-1 Is a lysosomal membrane protein required for intracellular lactosylceramide traffic. Traffic 7, 1388-1398
65. Lloyd-Evans, E., Waller-Evans, H., Peterneva, K. and Platt, F.M. (2010) Endoslysosomal calcium regulation and disease. Biochem. Soc. Trans. 38, 1458-1464
66. Piper, R.C. and Luzio, J.P. (2004) CUPpling calcium to lysosomal biogenesis. Trends Cell Biol. 14, 471-473
67. Luzio, J.P., Bright, N.A. and Pryor, P.R. (2007) The role of calcium and other ions in sorting and delivery in the late endocytic pathway. Biochem. Soc. Trans. 35, 1088-1091
68. Yamasaki, M., Churchill, G.C. and Galione, A. (2005) Calcium signalling by nicotinic acid adenine dinucleotide phosphate (NAADP). FEBS J. 272, 4598-4606
69. 2+ signals and contraction in arterial smooth muscle via a two-pool mechanism. Circ. Res. 91, 1168-1175
70. 2+ responses in clonal pancreatic β cells. Curr. Biol. 13, 247-251
71. Soares, S., Thompson, M., White, T., Isbell, A., Yamasaki, M., Prakash, Y., Lund, F.E., Galione, A. and Chini, E.N. (2007) NAADP as a second messenger: neither CD38 nor base-exchange reaction are necessary for in vivo generation of NAADP in myometrial cells. Am. J. Physiol. Cell Physiol. 292, C227-C239
72. Hwang, G.S., Jian, C.Y., Chen, T.J., Chen, S.T. and Wang, S.W. (2009) Effects of hypoxia on testosterone release in rat Leydig cells. Am. J. Physiol. Endocrinol. Metab. 297, E1039-E1045
73. Johnson, J.D. and Misler, S. (2002) Nicotinic acid-adenine dinucleotide phosphate-sensitive calcium stores initiate insulin signaling in human β cells. Proc. Natl. Acad. Sci. U.S.A. 99, 14566-14571
74. Alejandro, E.U., Kalynyak, T.B., Taghizadeh, F., Gwiazda, K.S., Rawstron, E.K., Jacob, K.J. and Johnson, J.D. (2010) Acute insulin signaling in pancreatic β-cells is mediated by multiple Raf-1 dependent pathways. Endocrinology 151, 502-512
75. 2+ signaling. J. Cell Biol. 150, 581-588
76. Gasser, A., Bruhn, S. and Guse, A.H. (2006) Second messenger function of nicotinic acid adenine dinucleotide phosphate revealed by an improved enzymatic cycling assay. J. Biol. Chem. 281, 16906-16913
77. Churchill, G.C., O'Neill, J.S., Masgrau, R., Patel, S., Thomas, J.M., Genazzani, A.A. and Galione, A. (2003) Sperm deliver a new second messenger: NAADP. Curr. Biol. 13, 125-128
78. +-ATPases in human platelets. Biochem. J. 390, 243-252
79. 2+ compartments show differential sensitivity to thrombin, ADP and vasopressin in human platelets. Cell. Signalling 18, 373-381
80. Blott, E.J. and Griffiths, G.M. (2002) Secretory lysosomes. Nat. Rev. Mol. Cell Biol. 3, 122-131
81. Vasudevan, S.R., Lewis, A.M., Chan, J.W., Machin, C.L., Sinha, D., Galione, A. and Churchill, G.C. (2010) The calcium-mobilizing messenger nicotinic acid adenine dinucleotide phosphate participates in sperm activation by mediating the acrosome reaction. J. Biol. Chem. 285, 18262-18269