메뉴 건너뛰기




Volumn 139, Issue 6, 2010, Pages

Up-regulation of krüppel-like factor 8 promotes tumor invasion and indicates poor prognosis for hepatocellular carcinoma

Author keywords

Liver Cancer; Metastatic Liver Cancer; siRNA; Small Interfering RNA; Tumor Microenvironment

Indexed keywords

FIBRONECTIN; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 8; NERVE CELL ADHESION MOLECULE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN;

EID: 78649710234     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2010.08.004     Document Type: Article
Times cited : (85)

References (49)
  • 2
    • 0037218312 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Present status and future prospects
    • J.M. Llovet, and M. Beaugrand Hepatocellular carcinoma: present status and future prospects J Hepatol 38 Suppl 2003 136 149
    • (2003) J Hepatol , vol.38 , Issue.SUPPL. , pp. 136-149
    • Llovet, J.M.1    Beaugrand, M.2
  • 3
    • 11144356989 scopus 로고    scopus 로고
    • A decade's studies on metastasis of hepatocellular carcinoma
    • Z.Y. Tang, S.L. Ye, and Y.K. Liu A decade's studies on metastasis of hepatocellular carcinoma J Cancer Res Clin Oncol 130 2004 187 196
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 187-196
    • Tang, Z.Y.1    Ye, S.L.2    Liu, Y.K.3
  • 4
    • 54449083925 scopus 로고    scopus 로고
    • Molecular targeted therapies in hepatocellular carcinoma
    • J.M. Llovet, and J. Bruix Molecular targeted therapies in hepatocellular carcinoma Hepatology 48 2008 1312 1327
    • (2008) Hepatology , vol.48 , pp. 1312-1327
    • Llovet, J.M.1    Bruix, J.2
  • 5
    • 0036782706 scopus 로고    scopus 로고
    • Transcription factors as targets for cancer therapy
    • J.E. Darnell Jr Transcription factors as targets for cancer therapy Nat Rev Cancer 2 2002 740 749
    • (2002) Nat Rev Cancer , vol.2 , pp. 740-749
    • Darnell Jr., J.E.1
  • 6
    • 36148977159 scopus 로고    scopus 로고
    • Nuclear receptor-mediated transactivation through interaction with Sp proteins
    • S. Safe, and K. Kim Nuclear receptor-mediated transactivation through interaction with Sp proteins Prog Nucleic Acid Res Mol Biol 77 2004 1 36
    • (2004) Prog Nucleic Acid Res Mol Biol , vol.77 , pp. 1-36
    • Safe, S.1    Kim, K.2
  • 7
    • 27544439766 scopus 로고    scopus 로고
    • Sp transcription factor family and its role in cancer
    • S. Safe, and M. Abdelrahim Sp transcription factor family and its role in cancer Eur J Cancer 41 2005 2438 2448
    • (2005) Eur J Cancer , vol.41 , pp. 2438-2448
    • Safe, S.1    Abdelrahim, M.2
  • 8
    • 33646435815 scopus 로고    scopus 로고
    • KLF4 and KLF5 regulate proliferation, apoptosis and invasion in esophageal cancer cells
    • Y. Yang, B.G. Goldstein, and H.H. Chao KLF4 and KLF5 regulate proliferation, apoptosis and invasion in esophageal cancer cells Cancer Biol Ther 4 2005 1216 1221
    • (2005) Cancer Biol Ther , vol.4 , pp. 1216-1221
    • Yang, Y.1    Goldstein, B.G.2    Chao, H.H.3
  • 9
    • 8844286089 scopus 로고    scopus 로고
    • A new role for the Kruppel-like transcription factor KLF6 as an inhibitor of c-Jun proto-oncoprotein function
    • D.A. Slavin, N.P. Koritschoner, and C.C. Prieto A new role for the Kruppel-like transcription factor KLF6 as an inhibitor of c-Jun proto-oncoprotein function Oncogene 23 2004 8196 8205
    • (2004) Oncogene , vol.23 , pp. 8196-8205
    • Slavin, D.A.1    Koritschoner, N.P.2    Prieto, C.C.3
  • 10
    • 34347358573 scopus 로고    scopus 로고
    • In vivo regulation of p21 by the Kruppel-like factor 6 tumor-suppressor gene in mouse liver and human hepatocellular carcinoma
    • G. Narla, S. Kremer-Tal, and N. Matsumoto In vivo regulation of p21 by the Kruppel-like factor 6 tumor-suppressor gene in mouse liver and human hepatocellular carcinoma Oncogene 26 2007 4428 4434
    • (2007) Oncogene , vol.26 , pp. 4428-4434
    • Narla, G.1    Kremer-Tal, S.2    Matsumoto, N.3
  • 11
    • 4143069155 scopus 로고    scopus 로고
    • KLF11 mediates a critical mechanism in TGF-β signaling that is inactivated by ERK-MAPK in pancreatic cancer cells
    • V. Ellenrieder, A. Buck, and A. Harth KLF11 mediates a critical mechanism in TGF-β signaling that is inactivated by ERK-MAPK in pancreatic cancer cells Gastroenterology 127 2004 607 620
    • (2004) Gastroenterology , vol.127 , pp. 607-620
    • Ellenrieder, V.1    Buck, A.2    Harth, A.3
  • 12
    • 0034178250 scopus 로고    scopus 로고
    • Human Kruppel-like factor 8: A CACCC-box binding protein that associates with CtBP and represses transcription
    • J. van Vliet, J. Turner, and M. Crossley Human Kruppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcription Nucleic Acids Res 28 2000 1955 1962
    • (2000) Nucleic Acids Res , vol.28 , pp. 1955-1962
    • Van Vliet, J.1    Turner, J.2    Crossley, M.3
  • 13
    • 34547620873 scopus 로고    scopus 로고
    • Kruppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion
    • X. Wang, M. Zheng, and G. Liu Kruppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion Cancer Res 67 2007 7184 7193
    • (2007) Cancer Res , vol.67 , pp. 7184-7193
    • Wang, X.1    Zheng, M.2    Liu, G.3
  • 14
    • 4344589523 scopus 로고    scopus 로고
    • Stepwise metastatic human hepatocellular carcinoma cell model system with multiple metastatic potentials established through consecutive in vivo selection and studies on metastatic characteristics
    • Y. Li, B. Tian, and J. Yang Stepwise metastatic human hepatocellular carcinoma cell model system with multiple metastatic potentials established through consecutive in vivo selection and studies on metastatic characteristics J Cancer Res Clin Oncol 130 2004 460 468
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 460-468
    • Li, Y.1    Tian, B.2    Yang, J.3
  • 15
    • 33845228344 scopus 로고    scopus 로고
    • Identification of metastasis candidate proteins among HCC cell lines by comparative proteome and biological function analysis of S100A4 in metastasis
    • J.F. Cui, Y.K. Liu, and L.J. Zhang Identification of metastasis candidate proteins among HCC cell lines by comparative proteome and biological function analysis of S100A4 in metastasis Proteomics 6 2006 5953 5961
    • (2006) Proteomics , vol.6 , pp. 5953-5961
    • Cui, J.F.1    Liu, Y.K.2    Zhang, L.J.3
  • 16
    • 0037391756 scopus 로고    scopus 로고
    • Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning
    • Q.H. Ye, L.X. Qin, and M. Forgues Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning Nat Med 9 2003 416 423
    • (2003) Nat Med , vol.9 , pp. 416-423
    • Ye, Q.H.1    Qin, L.X.2    Forgues, M.3
  • 17
    • 69949097533 scopus 로고    scopus 로고
    • CD24 is a novel predictor for poor prognosis of hepatocellular carcinoma after surgery
    • X.R. Yang, Y. Xu, and B. Yu CD24 is a novel predictor for poor prognosis of hepatocellular carcinoma after surgery Clin Cancer Res 15 2009 5518 5527
    • (2009) Clin Cancer Res , vol.15 , pp. 5518-5527
    • Yang, X.R.1    Xu, Y.2    Yu, B.3
  • 18
    • 34447277894 scopus 로고    scopus 로고
    • Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection
    • Q. Gao, S.J. Qiu, and J. Fan Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection J Clin Oncol 25 2007 2586 2593
    • (2007) J Clin Oncol , vol.25 , pp. 2586-2593
    • Gao, Q.1    Qiu, S.J.2    Fan, J.3
  • 19
    • 34848870566 scopus 로고    scopus 로고
    • Positive serum hepatitis B e antigen is associated with higher risk of early recurrence and poorer survival in patients after curative resection of hepatitis B-related hepatocellular carcinoma
    • H.C. Sun, W. Zhang, and L.X. Qin Positive serum hepatitis B e antigen is associated with higher risk of early recurrence and poorer survival in patients after curative resection of hepatitis B-related hepatocellular carcinoma J Hepatol 47 2007 684 690
    • (2007) J Hepatol , vol.47 , pp. 684-690
    • Sun, H.C.1    Zhang, W.2    Qin, L.X.3
  • 20
    • 52449093970 scopus 로고    scopus 로고
    • Cytokeratin 10 and cytokeratin 19: Predictive markers for poor prognosis in hepatocellular carcinoma patients after curative resection
    • X.Y. Yang, Y. Xu, and G.M. Shi Cytokeratin 10 and cytokeratin 19: predictive markers for poor prognosis in hepatocellular carcinoma patients after curative resection Clin Cancer Res 14 2008 3850 3859
    • (2008) Clin Cancer Res , vol.14 , pp. 3850-3859
    • Yang, X.Y.1    Xu, Y.2    Shi, G.M.3
  • 21
    • 44449085884 scopus 로고    scopus 로고
    • Design and endpoints of clinical trials in hepatocellular carcinoma
    • J.M. Llovet, A.M. Di Bisceglie, and J. Bruix Design and endpoints of clinical trials in hepatocellular carcinoma J Natl Cancer Inst 100 2008 698 711
    • (2008) J Natl Cancer Inst , vol.100 , pp. 698-711
    • Llovet, J.M.1    Di Bisceglie, A.M.2    Bruix, J.3
  • 22
    • 72949120827 scopus 로고    scopus 로고
    • Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma
    • M.H. Yang, C.L. Chen, and G.Y. Chau Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma Hepatology 50 2009 1464 1474
    • (2009) Hepatology , vol.50 , pp. 1464-1474
    • Yang, M.H.1    Chen, C.L.2    Chau, G.Y.3
  • 23
    • 38149015554 scopus 로고    scopus 로고
    • Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo
    • J. Sjolund, M. Johansson, and S. Manna Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo J Clin Invest 118 2008 217 228
    • (2008) J Clin Invest , vol.118 , pp. 217-228
    • Sjolund, J.1    Johansson, M.2    Manna, S.3
  • 24
    • 33748491718 scopus 로고    scopus 로고
    • Performance comparison of one-color and two-color platforms within the MicroArray Quality Control (MAQC) project
    • T.A. Patterson, E.K. Lobenhofer, and S.B. Fulmer-Smentek Performance comparison of one-color and two-color platforms within the MicroArray Quality Control (MAQC) project Nat Biotechnol 24 2006 1140 1150
    • (2006) Nat Biotechnol , vol.24 , pp. 1140-1150
    • Patterson, T.A.1    Lobenhofer, E.K.2    Fulmer-Smentek, S.B.3
  • 25
    • 0348223971 scopus 로고    scopus 로고
    • Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer
    • L. Wang, D. Wei, and S. Huang Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer Clin Cancer Res 9 2003 6371 6380
    • (2003) Clin Cancer Res , vol.9 , pp. 6371-6380
    • Wang, L.1    Wei, D.2    Huang, S.3
  • 26
    • 42049116522 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition and integrin-linked kinase mediate sensitivity to epidermal growth factor receptor inhibition in human hepatoma cells
    • B.C. Fuchs, T. Fujii, and J.D. Dorfman Epithelial-to-mesenchymal transition and integrin-linked kinase mediate sensitivity to epidermal growth factor receptor inhibition in human hepatoma cells Cancer Res 68 2008 2391 2399
    • (2008) Cancer Res , vol.68 , pp. 2391-2399
    • Fuchs, B.C.1    Fujii, T.2    Dorfman, J.D.3
  • 27
    • 33745297408 scopus 로고    scopus 로고
    • New signals from the invasive front
    • G. Christofori New signals from the invasive front Nature 441 2006 444 450
    • (2006) Nature , vol.441 , pp. 444-450
    • Christofori, G.1
  • 28
    • 28544446695 scopus 로고    scopus 로고
    • Biomarkers in cancer staging, prognosis and treatment selection
    • J.A. Ludwig, and J.N. Weinstein Biomarkers in cancer staging, prognosis and treatment selection Nat Rev Cancer 5 2005 845 856
    • (2005) Nat Rev Cancer , vol.5 , pp. 845-856
    • Ludwig, J.A.1    Weinstein, J.N.2
  • 29
    • 4544301860 scopus 로고    scopus 로고
    • High α-fetoprotein level correlates with high stage, early recurrence and poor prognosis of hepatocellular carcinoma: Significance of hepatitis virus infection, age, p53 and β-catenin mutations
    • S.Y. Peng, W.J. Chen, and P.L. Lai High α-fetoprotein level correlates with high stage, early recurrence and poor prognosis of hepatocellular carcinoma: significance of hepatitis virus infection, age, p53 and β-catenin mutations Int J Cancer 112 2004 44 50
    • (2004) Int J Cancer , vol.112 , pp. 44-50
    • Peng, S.Y.1    Chen, W.J.2    Lai, P.L.3
  • 30
    • 4344590372 scopus 로고    scopus 로고
    • Recent progress in predictive biomarkers for metastatic recurrence of human hepatocellular carcinoma: A review of the literature
    • L.X. Qin, and Z.Y. Tang Recent progress in predictive biomarkers for metastatic recurrence of human hepatocellular carcinoma: a review of the literature J Cancer Res Clin Oncol 130 2004 497 513
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 497-513
    • Qin, L.X.1    Tang, Z.Y.2
  • 31
    • 20144388992 scopus 로고    scopus 로고
    • Signaling pathways associated with colonic mucosa hyperproliferation in mice overexpressing gastrin precursors
    • A. Ferrand, C. Bertrand, and G. Portolan Signaling pathways associated with colonic mucosa hyperproliferation in mice overexpressing gastrin precursors Cancer Res 65 2005 2770 2777
    • (2005) Cancer Res , vol.65 , pp. 2770-2777
    • Ferrand, A.1    Bertrand, C.2    Portolan, G.3
  • 32
    • 37549029111 scopus 로고    scopus 로고
    • Inhibition of membrane-type 1 matrix metalloproteinase at cell-matrix adhesions
    • T. Takino, H. Saeki, and H. Miyamori Inhibition of membrane-type 1 matrix metalloproteinase at cell-matrix adhesions Cancer Res 67 2007 11621 11629
    • (2007) Cancer Res , vol.67 , pp. 11621-11629
    • Takino, T.1    Saeki, H.2    Miyamori, H.3
  • 33
    • 34547122752 scopus 로고    scopus 로고
    • Matrix metalloproteinase 7 mediates mammary epithelial cell tumorigenesis through the ErbB4 receptor
    • C.C. Lynch, T. Vargo-Gogola, and M.D. Martin Matrix metalloproteinase 7 mediates mammary epithelial cell tumorigenesis through the ErbB4 receptor Cancer Res 67 2007 6760 6767
    • (2007) Cancer Res , vol.67 , pp. 6760-6767
    • Lynch, C.C.1    Vargo-Gogola, T.2    Martin, M.D.3
  • 34
    • 18844394310 scopus 로고    scopus 로고
    • The Ras suppressor Rsu-1 binds to the LIM 5 domain of the adaptor protein PINCH1 and participates in adhesion-related functions
    • G.W. Dougherty, T. Chopp, and S.M. Qi The Ras suppressor Rsu-1 binds to the LIM 5 domain of the adaptor protein PINCH1 and participates in adhesion-related functions Exp Cell Res 306 2005 168 179
    • (2005) Exp Cell Res , vol.306 , pp. 168-179
    • Dougherty, G.W.1    Chopp, T.2    Qi, S.M.3
  • 35
    • 33751301603 scopus 로고    scopus 로고
    • Distinct roles for IFN regulatory factor (IRF)-3 and IRF-7 in the activation of antitumor properties of human macrophages
    • R. Romieu-Mourez, M. Solis, and A. Nardin Distinct roles for IFN regulatory factor (IRF)-3 and IRF-7 in the activation of antitumor properties of human macrophages Cancer Res 66 2006 10576 10585
    • (2006) Cancer Res , vol.66 , pp. 10576-10585
    • Romieu-Mourez, R.1    Solis, M.2    Nardin, A.3
  • 36
    • 10844253962 scopus 로고    scopus 로고
    • Cyclin G2 dysregulation in human oral cancer
    • Y. Kim, S. Shintani, and Y. Kohno Cyclin G2 dysregulation in human oral cancer Cancer Res 64 2004 8980 8986
    • (2004) Cancer Res , vol.64 , pp. 8980-8986
    • Kim, Y.1    Shintani, S.2    Kohno, Y.3
  • 37
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
    • H.B. El-Serag, and K.L. Rudolph Hepatocellular carcinoma: epidemiology and molecular carcinogenesis Gastroenterology 132 2007 2557 2576
    • (2007) Gastroenterology , vol.132 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 38
    • 69949097533 scopus 로고    scopus 로고
    • CD24 is a novel predictor for poor prognosis of hepatocellular carcinoma after surgery
    • X.R. Yang, Y. Xu, and B. Yu CD24 is a novel predictor for poor prognosis of hepatocellular carcinoma after surgery Clin Cancer Res 15 2009 5518 5527
    • (2009) Clin Cancer Res , vol.15 , pp. 5518-5527
    • Yang, X.R.1    Xu, Y.2    Yu, B.3
  • 39
    • 34447277894 scopus 로고    scopus 로고
    • Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection
    • Q. Gao, S.J. Qiu, and J. Fan Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection J Clin Oncol 25 2007 2586 2593
    • (2007) J Clin Oncol , vol.25 , pp. 2586-2593
    • Gao, Q.1    Qiu, S.J.2    Fan, J.3
  • 40
    • 0036534375 scopus 로고    scopus 로고
    • Tumor microvessel density as a predictor of recurrence after resection of hepatocellular carcinoma: A prospective study
    • R.T. Poon, I.O. Ng, and C. Lau Tumor microvessel density as a predictor of recurrence after resection of hepatocellular carcinoma: a prospective study J Clin Oncol 20 2002 1775 1785
    • (2002) J Clin Oncol , vol.20 , pp. 1775-1785
    • Poon, R.T.1    Ng, I.O.2    Lau, C.3
  • 42
    • 33745684092 scopus 로고    scopus 로고
    • Pitfalls in the classification of liver tumors
    • C. Wittekind Pitfalls in the classification of liver tumors Pathologe 27 2006 289 293
    • (2006) Pathologe , vol.27 , pp. 289-293
    • Wittekind, C.1
  • 44
    • 44449085884 scopus 로고    scopus 로고
    • Design and endpoints of clinical trials in hepatocellular carcinoma
    • J.M. Llovet, A.M. Di Bisceglie, and J. Bruix Design and endpoints of clinical trials in hepatocellular carcinoma J Natl Cancer Inst 100 2008 698 711
    • (2008) J Natl Cancer Inst , vol.100 , pp. 698-711
    • Llovet, J.M.1    Di Bisceglie, A.M.2    Bruix, J.3
  • 45
    • 52449093970 scopus 로고    scopus 로고
    • Cytokeratin 10 and cytokeratin 19: Predictive markers for poor prognosis in hepatocellular carcinoma patients after curative resection
    • X.R. Yang, Y. Xu, and G.M. Shi Cytokeratin 10 and cytokeratin 19: predictive markers for poor prognosis in hepatocellular carcinoma patients after curative resection Clin Cancer Res 14 2008 3850 3859
    • (2008) Clin Cancer Res , vol.14 , pp. 3850-3859
    • Yang, X.R.1    Xu, Y.2    Shi, G.M.3
  • 46
    • 34848870566 scopus 로고    scopus 로고
    • Positive serum hepatitis B e antigen is associated with higher risk of early recurrence and poorer survival in patients after curative resection of hepatitis B-related hepatocellular carcinoma
    • H.C. Sun, W. Zhang, and L.X. Qin Positive serum hepatitis B e antigen is associated with higher risk of early recurrence and poorer survival in patients after curative resection of hepatitis B-related hepatocellular carcinoma J Hepatol 47 2007 684 690
    • (2007) J Hepatol , vol.47 , pp. 684-690
    • Sun, H.C.1    Zhang, W.2    Qin, L.X.3
  • 47
    • 72949120827 scopus 로고    scopus 로고
    • Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma
    • M.H. Yang, C.L. Chen, and G.Y. Chau Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma Hepatology 50 2009 1464 1474
    • (2009) Hepatology , vol.50 , pp. 1464-1474
    • Yang, M.H.1    Chen, C.L.2    Chau, G.Y.3
  • 48
    • 38149015554 scopus 로고    scopus 로고
    • Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo
    • J. Sjolund, M. Johansson, and S. Manna Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo J Clin Invest 118 2008 217 228
    • (2008) J Clin Invest , vol.118 , pp. 217-228
    • Sjolund, J.1    Johansson, M.2    Manna, S.3
  • 49
    • 34547620873 scopus 로고    scopus 로고
    • Kruppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion
    • X. Wang, M. Zheng, and G. Liu Kruppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion Cancer Res 67 2007 7184 7193
    • (2007) Cancer Res , vol.67 , pp. 7184-7193
    • Wang, X.1    Zheng, M.2    Liu, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.