Ethanol extract of Fructus Ligustri Lucidi increases circulating 1,25-dihydroxyvitamin D3 by inducing renal 25-hydroxyvitamin D-1α hydroxylase activity

Menopause

Volumn 17, Issue 6, 2010, Pages 1174-1181

  Dong, Xiao Li ^a,b   Zhang, Yan ^a,c   Favus, Murray J ^c   Che, Chun Tao ^d   Wong, Man Sau ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b QINGDAO UNIVERSITY MEDICAL COLLEGE   (China)

^c UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGY   (China)

^d CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

25 Hydroxyvitamin D 1 hydroxylase; Fructus Ligustri Lucidi; Vitamin D metabolism; Vitamin D receptor

Indexed keywords

25 HYDROXYVITAMIN D OXYGENASE; ALCOHOL; CALCITRIOL; CALCIUM; LIGUSTRUM LUCIDUM EXTRACT; MESSENGER RNA; OXYGENASE; PARATHYROID HORMONE; PHOSPHATE; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM BALANCE; CALCIUM BLOOD LEVEL; CALCIUM INTAKE; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; ENZYME IMMUNOASSAY; ENZYME INDUCTION; FEMALE; FRUIT; GENE EXPRESSION REGULATION; KIDNEY PROXIMAL TUBULE; MONOLAYER CULTURE; NONHUMAN; OVARIECTOMY; PARATHYROID HORMONE BLOOD LEVEL; PHOSPHATE BLOOD LEVEL; POSTMENOPAUSE OSTEOPOROSIS; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; TREATMENT DURATION; VITAMIN BLOOD LEVEL; VITAMIN D METABOLISM; WESTERN BLOTTING;

EID: 78649673025     PISSN: 10723714     EISSN: None     Source Type: Journal    
DOI: 10.1097/gme.0b013e3181e39a2b     Document Type: Article

References (39)

1. Wang T, Zeng Y, Xu M. Studies on quality control of Gushuling capsule. Tradit Chin Drug Res Clin Pharmacol 2003;14:403-405.
2. Shi LF, Yuan YF, Yuan HJ. TLC studies on the active constituents of Fructus Ligustri Lucidi and derivatives of the constituents. Pharm Care Res 2006;6:48-50.
3. Xu H, Lawson D, Kras A, Ryan D. The use of preventive strategies for bone loss. Am J Chin Med 2005;33:299-306.
4. Zhang Y, Lai WP, Leung PC, Che CT, Wong MS. Improvement of Ca balance by Fructus Ligustri Lucidi extract in aged female rats. Osteoporos Int 2008;19:235-242.
5. Zhang Y, Lai WP, Leung PC, Wu CF, Yao XS, Wong MS. Effects of Fructus Ligustri Lucidi extract on bone turnover and calcium balance in ovariectomized rats. Biol Pharm Bull 2006;29:291-296. (Pubitemid 43200899)
6. Eeleen G. Molecular Modes of Action of 1>,25-Dihydroxyvitamin D3 and Analogs. Leuven, Belgium: Leuven University Press, 2005.
7. Feldman D, Glorieux FH, Pike JW. Vitamin D. San Diego, CA: Academic Press, 1997.
8. Dusso AS, Brown AJ, Slatopolsky E. Vitamin D. Am J Physiol Renal Physiol 2005;289:F8-F28.
9. Tissandie E, Gueguen Y, Lobaccaro JM, et al. In vivo effects of chronic contamination with depleted uranium on vitamin D3 metabolism in rat. Biochim Biophys Acta 2007;1770:266-272.
10. Friedlander J, Janulis M, Tembe V, Ro HK, Wong MS, Favus MJ. Loss of parathyroid hormoneYstimulated 1,25-dihydroxyvitamin D3 production in aging does not involve protein kinase A or C pathways. J Bone Miner Res 1994;9:339-345.
11. Laktasic-Zerjavic N, Korsic M, Crncevic-Orlic Z, Kovac Z, Polasek O, Soldo-Juresa D. Vitamin D status, dependence on age, and seasonal variations in the concentration of vitamin D in Croatian postmeno-pausal women initially screened for osteoporosis [e-pub]. Clin Rheumatol 2010.
12. Wu S, Ren S, Nguyen L, Adams JS, Hewison M. Splice variants of the CYP27b1 gene and the regulation of 1,25-dihydroxyvitamin D3 production. Endocrinology 2007;148:3410-3418.
13. Rost CR, Bikle DD, Kaplan RA. In vitro stimulation of 25-hydroxycholecalciferol 1>-hydroxylation by parathyroid hormone in chick kidney slices: evidence for a role for adenosine 3¶,5¶-monophosphate. Endocrinology 1981;108:1002-1006.
14. Kremer R, Goltzman D. Parathyroid hormone stimulates mammalian renal 25-hydroxyvitamin D3-1>-hydroxylase in vitro. Endocrinology 1982;110:294-296.
15. Murayama A, Takeyama K, Kitanaka S, et al. Positive and negative regulations of the renal 25-hydroxyvitamin D3 1>-hydroxylase gene by parathyroid hormone, calcitonin, and 1>,25(OH)2D3 in intact animals. Endocrinology 1999;140:2224-2231.
16. Avila E, Diaz L, Barrera D, et al. Regulation of Vitamin D hydroxylases gene expression by 1,25-dihydroxyvitamin D3 and cyclic AMP in cultured human syncytiotrophoblasts. J Steroid Biochem Mol Biol 2007; 103:90-96.
17. Portale AA, Halloran BP, Morris RC Jr. Physiologic regulation of the serum concentration of 1,25-dihydroxyvitamin D by phosphorus in normal men. J Clin Invest 1989;83:1494-1499.
18. Baksi SN, Kenny AD. Estradiol-induced stimulation of 25-hydroxyvitamin D3-1-hydroxylase in vitamin DYdeficient Japanese quail. Pharmacology 1980;20:298-303.
19. Lechner D, Bajna E, Adlercreutz H, Cross HS. Genistein and 17A-estradiol, but not equol, regulate vitamin D synthesis in human colon and breast cancer cells. Anticancer Res 2006;26:2597-2603.
20. Healy KD, Zella JB, Prahl JM, DeLuca HF. Regulation of the murine renal vitamin D receptor by 1,25-dihydroxyvitamin D3 and calcium. Proc Natl Acad Sci USA 2003;100:9733-9737.
21. 3 levels in vivo. Arch Biochem Biophys 2002;401:44-52.
22. Bajwa A, Horst RL, Beckman MJ. Gene profiling the effects of calcium deficiency versus 1,25-dihydroxyvitamin D induced hypercalcemia in rat kidney cortex. Arch Biochem Biophys 2005;438:182-194.
23. Healy KD, Frahm MA, DeLuca HF. 1,25-Dihydroxyvitamin D3 up-regulates the renal vitamin D receptor through indirect gene activation and receptor stabilization. Arch Biochem Biophys 2005;433:466-473.
24. Ross TK, Darwish HM, DeLuca HF. Molecular biology of vitamin D action. Vitam Horm 1994;49:281-326.
25. Brown AJ, Zhong M, Finch J, Ritter C, Slatopolsky E. The roles of calcium and 1,25-dihydroxyvitamin D3 in the regulation of vitamin D receptor expression by rat parathyroid glands. Endocrinology 1995;136: 1419-1425.
26. Zhang Y, Dong XL, Leung PC, Che CT, Wong MS. Fructus Ligustri Lucidi extract improves calcium balance and modulates the calciotropic hormone level and vitamin D-dependent gene expression in aged ovari-ectomized rats. Menopause 2008;15:558Y565.
27. Zhang Y, Leung PC, Che CT, Chow HK, Wu CF, Wong MS. Improvement of bone properties and enhancement of mineralization by ethanol extract of Fructus Ligustri Lucidi. Br J Nutr 2008;99:494-502.
28. National Research Council. Guide for the Care and the Use of Laboratory Animals. Washington, DC: National Academy Press 2006.
29. Vinay P, Gougoux A, Lemieux G. Isolation of a pure suspension of rat proximal tubules. Am J Physiol 1981;241:F403-F411.
30. Wong MS, Tembe VA, Favus MJ. Insulin-like growth factor-I stimulates renal 1,25-dihydroxycholecalciferol synthesis in old rats fed a low calcium diet. J Nutr 2000;130:1147-1152.
31. Bland R, Walker EA, Hughes SV, Stewart PM, Hewison M. Constitutive expression of 25-hydroxyvitamine D3-1>-hydroxylase in a transformed human proximal tubule cell line: evidence for direct regulation of vitamin D metabolism by calcium. Endocrinology 1999;140:2027-2034.
32. Schwartz GG, Whitlatch LW, Chen TC, Lokeshwar BL, Holick MF. Human prostate cells synthesize 1,25-dihydroxyvitamine D3 from 25-hydroxyvitamin D3. Cancer Epidemiol Biomarkers Prev 1998;7:391-395.
33. Zhang Y, Lai WP, Wu CF, Favus MJ, Leung PC, Wong MS. Ovariec-tomy worsens secondary hyperparathyroidism in mature rats during low-Ca diet. Am J Physiol Endocrinol Metab 2007;292:E723-E731.
34. Hewison M, Zehnder D, Bland R, Stewart PM. 1>-Hydroxylase and the action of vitamin D. J Mol Endocrinol 2000;25:141-148.
35. Chau TS, Lai WP, Cheung PY, Favus MJ, Wong MS. Age-related alteration of vitamin D metabolism in response to low-phosphate diet in rats. Br J Nutr 2005;93:299-307.
36. Radermacher J, Diesel B, Seifert M, et al. Expression analysis of CYP27B1 in tumor biopsies and cell cultures. Anticancer Res 2006; 26:2683-2686.
37. Perwad F, Zhang MY, Tenenhouse HS, Portale AA. Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1>-hydroxylase expression in vitro. Am J Physiol Renal Physiol 2007;293:F1577-F1583.
38. 3 metabolism in human glioblastoma multiforme: functionality of CYP27B1 splice variants, metabolism of calcidiol, and effect of calcitriol. Clin Cancer Res 2005;11:5370-5380.
39. Holick MF. Optimal vitamin D status for the prevention and treatment of osteoporosis. Drugs Aging 2007;24:1017-1029.