Ovariectomy worsens secondary hyperparathyroidism in mature rats during low-Ca diet

American Journal of Physiology - Endocrinology and Metabolism

Volumn 292, Issue 3, 2007, Pages

  Zhang, Yan ^a,b   Lai, Wan Ping ^a,c   Wu, Chun Fu ^b   Favus, Murray J ^d   Leung, Ping Chung ^e   Wong, Man Sau ^a,c  

^a State Key Laboratory of Chinese Medicine and Molecular Pharmacology   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^d UNIVERSITY OF CHICAGO   (United States)

^e CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Dietary Ca restriction; Parathyroid hormone; Renal 25 hydroxyvitamin D1 hydroxylase; Renal vitamin D receptor

Indexed keywords

CALBINDIN; CALCIDIOL 1 MONOOXYGENASE; CALCITRIOL; CALCIUM; CALCIUM TRANSPORTER 1; CARRIER PROTEIN; MESSENGER RNA; PARATHYROID HORMONE; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE STRENGTH; CALCIUM ABSORPTION; CALCIUM BONE LEVEL; CONTROLLED STUDY; DIET RESTRICTION; FEMALE; INTESTINE ABSORPTION; METAPHYSIS; NONHUMAN; OVARIECTOMY; PARATHYROID HORMONE BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SECONDARY HYPERPARATHYROIDISM; VITAMIN BLOOD LEVEL;

25-HYDROXYVITAMIN D3 1-ALPHA-HYDROXYLASE; ANIMALS; BODY WEIGHT; CALCITRIOL; CALCIUM; CALCIUM, DIETARY; ESTROGENS; FEMALE; HYPERPARATHYROIDISM, SECONDARY; KIDNEY; OVARIECTOMY; PARATHYROID HORMONE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CALCITRIOL; UTERUS;

EID: 33947100420     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00445.2006     Document Type: Article

References (45)

1. Albright F, Smith PH, Richardson AM. Postmenopausal osteoporosis. JAMA 116: 2465-2474, 1941.
2. Arjamndi BH, Hollis BW, Kalu DN. In vivo effect of 17b-estradiol on intestinal calcium absorption in rats. Bone Miner 26: 181-189, 1994.
3. Arjmandi BH, Salih MA, Herbert DC, Sims SH, Kalu DN. Evidence for estrogen receptor-linked calcium transport in the intestine. Bone Miner 21: 63-74, 1993.
4. Armbrecht HJ, Boltz MA, Bruns ME. Effect of age and dietary calcium on intestinal calbindin D-9K expression in the rat. Arch Biochem Biophys 420: 194-200, 2003.
5. 2D, and PTH. Am J Physiol Endocrinol Metab 246: E266-E270, 1984.
6. Armbrecht HJ, Hodam TL, Boltz MA, Kumar VB. Capacity of a low calcium diet to induce the renal vitamin D 1α-hydroxylase is decreased in adult rats. Biochem Biophys Res Commun 255: 731-734, 1999.
7. Ash SL, Goldin BR. Effects of age and estrogen on renal vitamin D metabolism in the female rat. Am J Clin Nutr 47: 694-699, 1988.
8. 3 metabolism in immature Japanese quail: effects of ovarian hormones. Endocrinology 101: 2701-2705, 1977.
9. Bolscher MT, Netelenbos JC, Barto R, Van Burren LM, Van der Vijgh WJF. Estrogen regulation of intestinal calcium absorption in the intact and ovariectomized adult rat. J Bone Miner Res 14: 1197-1202, 1999.
10. Bouillon R, Cromphaut SV, Carmeliet G. Intestinal calcium absorption: molecular vitamin D mediated mechanisms. J Cell Biochem 88: 332-339, 2003.
11. 3 1-α-hydroxylase gene promoter. Proc Natl Acad Sci USA 95: 1387-1391, 1998.
12. Chau TS, Lai WP, Cheung PK, Favus MJ, Wong MS. Age-related alteration of vitamin D metabolism in response to low phosphate diet in rats. Br J Nutr 93: 299-307, 2005.
13. Cheema C, Grant BF, Marcus R. Effects of estrogen on circulating "free" and total 1,25-dihydroxyvitamin D and on the parathyroid-vitamin D axis in postmenopausal women. J Clin Invest 83: 537-542, 1989.
14. 3 level in the rat. J Bone Miner Res 14: 57-64, 1999.
15. Cosman F, Shen V, Xie F, Seibel M, Ratcliffe A, Lindsay R. Estrogen protection against bone resorbing effects of parathyroid hormone infusion. Ann Intern Med 118: 337-343, 1993.
16. Cotter AA, Cashman KD. Effect of 17β-oestradiol on transepithelial calcium transport in human intestinal-like Caco-2 cells and its interactions with 1,25-dihydroxycholecalciferol and 9-cis retinoic acid. Eur J Nutr 45: 234-241, 2006.
17. Dick IM, St John A, Heal S, Prince RL. The effect of estrogen deficiency on bone mineral density, renal calcium and phosphorus handling and calcitropic hormones in the rat. Calcif Tissue Int 59: 174-178, 1996.
18. 3 production in aging does not involve protein kinase A or protein kinase C pathways. J Bone Miner Res 9: 339-345, 1994.
19. Gallagher JC, Riggs BL, DeLuca HK. Effect of estrogen on calcium absorption and serum vitamin D metabolites in postmenopausal osteoporosis. J Clin Endocrinol Metab 51: 1359-1364, 1980.
20. Geng W, DeMoss DL, Wright GL. Effect of calcium stress on the skeleton mass of intact and ovariectomized rats. Life Sci 66: 2309-2321, 2000.
21. Healy KD, Vanhooke JL, Prahol JM, DeLuca HF. Parathyroid hormone decreases renal vitamin D receptor expression in vivo. Proc Natl Acad Sci USA 102: 4724-4728, 2005.
22. 3 and calcium. Proc Natl Acad Sci USA 100: 9733-9737, 2003.
23. Heaney RP, Recker RR, Stegman MR, Moy AJ. Calcium absorption in women: relationships to calcium intake, estrogen status and age. J Bone Miner Res 4: 469-475, 1989.
24. 3 metabolism in kidney cell cultures: lack of a direct effect of estradiol. Am J Physiol Endocrinol Metab 240: E119-E124, 1981.
25. Henry HL. The 25-hydroxyvitamin D3 1α-hydroxylase In: Vitamin D, edited by Feldman D, Glorieux FH, Pike JW. San Diego, CA: Academic, 1997, p. 57-68.
26. Kalu DN, Orhii PB. Calcium absorption and bone loss in ovariectomized rats fed varying levels of dietary calcium. Calcif Tissue Int 65: 73-77, 1999.
27. Khosla S, Atkinson EJ, Melton J 3rd, Riggs BL. Effects of age and estrogen status on serum parathyroid hormone levels and biochemical markers of bone turnover in women: a population-based study. J Clin Endocrinol Metab 82: 1522-1527, 1997.
28. Lai WP, Chau TS, Cheung PK, Chen WF, Lo SCL, Favus MJ, Wong MS. Adaptive responses of 25-hydroxyvitamin D3 1-alpha hydroxylase expression to dietary phosphate restriction in young and adult rats. Biochim Biophys Acta 1639: 34-42, 2003.
29. Liel Y, Shany S, Smirnoff P, Schwartz B. Estrogen increases 1,25-dihydroxyvitamin D receptors expression and bioresponse in the rat duodenal mucosa. Endocrinology 140: 280-285, 1999.
30. Lindsay R, Altkin JM, Anderson JB, Hart DM, MacDonald EB, Clarke AC. Long-term prevention of postmenopausal osteoporosis by oestrogen. Evidence for an increased bone mass after delayed onset of oestrogen treatment. Lancet 1: 1038-1041, 1976.
31. McKane WR, Khosla S, Egan KS, Robins SP, Burritt MF, Riggs BL. Role of calcium intake in modulating age-related increases in parathyroid function and bone resorption. J Clin Endocrinol Metab 81: 1699-1703, 1996.
32. McKane WR, Khosla S, Risteli J, Robins SP, Muhs JM, Riggs BL. Role of estrogen deficiency in pathogenesis of secondary hyperparathyroidism and increased bone resorption in elderly women. Proc Assoc Am Physicians 109: 174-180, 1997.
33. 3 in intact animals. Endocrinology 140: 2224-2231, 1999.
34. 3 in chicks. Am J Physiol Endocrinol Metab Gastrointest Physiol 235: E119-E124, 1978.
35. Prince RL. Estrogen effects on calcitropic hormones and calcium homeostasis. Endocr Rev 15: 301-309, 1994.
36. Prince RL, Dick I, Garcia-Webb P, Retallack RW. The effects of the menopause on calcitriol and parathyroid hormone: responses to a low dietary calcium stress test. J Clin Endocrinol Metab 70: 1119-1123, 1990.
37. Raisz LG. Pathogenesis of osteoporosis: concepts, conflicts and prospects. J Clin Invest 115: 3318-3325, 2005.
38. Riggs BL. Role of the vitamin D-endocrine system in the pathophysiology of postmenopausal osteoporosis. J Cell Biochem 88: 209-215, 2003.
39. Riggs BL, Khosla S, Melton LJ. A unitary model for involutional osteoporosis: estrogen deficiency causes both Type I and Type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. J Bone Miner Res 13: 763-773, 1998.
40. Sapnos E, Barrett DI, Chong KT, MacIntyre I. Effect of oestrogen and 1,25-dihydroxycholecalciferol metabolism in primary chick kidney cell cultures. Biochem J 174: 231-236, 1978.
41. Song Y, Fleet JC. 1,25-Dihydroxycholecalciferol-mediated calcium absorption and gene expression are higher in female than in male mice. J Nutr 134: 1857-1861, 2004.
42. 3 in the intestine and kidney of mice. Endocrinology 144: 3885-3894, 2003.
43. Tanaka Y, Castillo L, Deluca HF. Control of renal vitamin D hydroxylases in birds by sex hormones. Proc Natl Acad Sci USA 73: 2701-2705, 1976.
44. Trechsel U, Bonjour JP, Fleisch H. Regulation of the metabolism of 25-hydroxyvitamin D3 in primary cultures of chick kidney cells. J Clin Invest 64: 206-217, 1979.
45. Wong MS, Tembe VA, Favus MJ. Insulin-like growth factor-I stimulates renal 1,25-dihydroxycholecalciferol synthesis in old rats fed a low calcium diet. J Nutr 130: 1147-1152, 2000.