Age-related alteration of vitamin D metabolism in response to low-phosphate diet in rats

British Journal of Nutrition

Volumn 93, Issue 3, 2005, Pages 299-307

  Chau, Tsui Shan ^a   Lai, Wan Ping ^a   Cheung, Pik Yuen ^a   Favus, Murray J ^b   Wong, Man Sau ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

25 Hydroxyvitamin D3 1 hydroxylase; 25 Hydroxyvitamin D3 24 hydroxylase; Adult rats; Low phosphate diet; Vitamin D receptor

Indexed keywords

CALCITRIOL; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; PHOSPHATE; VITAMIN D; VITAMIN D RECEPTOR; 1,25-DIHYDROXYVITAMIN D; CALCITRIOL RECEPTOR; CALCIUM; CYTOCHROME P450; DRUG DERIVATIVE; STEROID MONOOXYGENASE; VITAMIN D 24 HYDROXYLASE; VITAMIN D 24-HYDROXYLASE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIET; ENZYME REPRESSION; GENE EXPRESSION; KIDNEY METABOLISM; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; VITAMIN METABOLISM; AGE; AGING; ANIMAL; BLOOD; DOWN REGULATION; GENETICS; KIDNEY; METABOLISM; SPRAGUE DAWLEY RAT; WEIGHT GAIN;

ANIMALIA;

AGE FACTORS; AGING; ANIMALS; CALCIUM; CYTOCHROME P-450 ENZYME SYSTEM; DIET; DOWN-REGULATION; KIDNEY; MALE; PHOSPHATES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CALCITRIOL; RNA, MESSENGER; STEROID HYDROXYLASES; VITAMIN D; WEIGHT GAIN;

EID: 22144493865     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1079/BJN20041325     Document Type: Article

References (43)

1. Akiyoshi-Shibata M, Sakaki T, Ohyama Y, Noshiro M, Okuda K & Yabusaki Y (1994) Further oxidation of hydroxycalcidiol by calcidiol 24-hydroxylase. Eur J Biochem 224, 335-343.
2. Armbrecht HJ, Forte LR & Halloran BP (1984) Effect of age and dietary calcium on renal 25(OH)D metabolism, serum 1,25(OH)2D, and PTH. Am J Physiol 246, E266-E270.
3. 3 production in adult rats. Am J Physiol Renal Physiol 284, F1032-F1036.
4. Armbrecht HJ, Hodam TL, Boltz MA & Kumar VB (1999) Capacity of a low calcium diet to induce the renal vitamin D 1α-hydroxylase is decreased in adult rats. Biochem Biophys Res Commun 255, 731-734.
5. 3 production of young and adult rats. Endocrinology 111, 1339-1344.
6. Armbrecht HJ, Zenser TV & Davis BB (1980) Effect of age on the conversion of 25-hydroxyvitamin D3 to 1,25-dihydroxyvitamin D3 by kidney of rat. J Clin Invest 66, 1118-1123.
7. 47Ca absorption in postmenopausal women. J Clin Invest 44, 1960-1967.
8. Beckman MJ & DeLuca HK (2002) Regulation of renal vitamin D receptor is an important determinant of 1alpha,25-dihydroxyvitamin D(3) levels in vivo. Arch Biochem Biophys 401, 44-52.
9. Clemens TL, Zhou XY, Myles M, Endres D & Lindsay R (1986) Serum vitamin D2 and vitamin D3 metabolite concentrations and absorption of vitamin D2 in elderly subjects. J Clin Endocrinol Metab 63, 656-660.
10. Condamine L, Vrtovsnik F, Friedlander G & Garabedian M (1994) Local action of phosphate depletion and insulin-like growth factor 1 on in vitro production of 1,25-dihydroxyvitamin D by cultured mammalian kidney cells. J Clin Invest 94, 1673-1679.
11. Dick IM, Retallack R & Prince RL (1990) Rapid nongenomic inhibition of renal 25-hydroxyvitamin D3 1-hydroxylase by 1,25-dihydroxyvitamin D3. Am J Physiol 259, E272-E277.
12. Favus MJ & Tembe V (1992) The use of pharmacologic agents to study mechanisms of intestinal calcium transport. J Nutr 122, Suppl., 683-686.
13. 3 production in aging does not involve protein kinase A or protein kinase C pathways. J Bone Miner Res 9, 339-345.
14. Gallagher JC, Riggs BL, Eisman JA, Hamstra A, Arnaud SB & Deluca HF (1979) Intestinal calcium absorption and serum vitamin D metabolites in normal subjects and osteoporotic patients. J Clin Invest 64, 729-736.
15. Garabedian M, Holick MF, DeLuca HF & Boyle BL (1972) Control of 25-hydroxycholecalciferol metabolism by parathyroid glands. Proc Natl Acad Sci USA 69, 1673-1676.
16. 3 level in rats. Endocrinology 121, 504-512.
17. 2 vitamin D in the rat. Age 5, 54-56.
18. Gray RW & Garthwaite TL (1985) Activation of renal 1,25-dihydroxyvitamin D3 synthesis by phosphate deprivation: evidence for a role for growth hormone. Endocrinology 116, 189-193.
19. Healy KD, Zella JB, Prahl JM & DeLuca HF (2003) Regulation of the murine renal vitamin D receptor by 1,25-dihydroxyvitamin D3 and calcium. Proc Natl Acad Sci USA 100, 9733-9737.
20. Halloran BP & Spencer EM (1988) Dietary phosphorus and 1,25-dihydroxyvitamin D metabolism: influence of insulin-like growth factor I. Endocrinology 123, 1225-1229.
21. Henry HL & Norman AW (1974) Studies on calciferol metabolism. IX. Renal 25-hydroxy-vitamin D3-1 hydroxylase. Involvement of cytochrome P-450 and other properties. J Biol Chem 249, 7529-7535.
22. 3 by calcium and phosphate in the rat. Science 190, 578-579.
23. Jones G, Strugnell SA & DeLuca HF (1998) Current understanding of the molecular actions of vitamin D. Physiol Rev 78, 1193-1231.
24. 3 1-alpha hydroxylase expression to dietary phosphate restriction in young and adult rats. Biochim Biophys Acta 1639, 34-42.
25. Lee DBN, Brautbar N, Walling MW, Silis V, Oburn CJW & Kleeman CR (1979) Effect of phosphorus depletion on intestinal calcium and phosphorus absorption. Am J Physiol 236, E451-E457.
26. Malm OJ, Nickolaysen R & Skjelkvale L (1955) Calcium metabolism in old age as related to ageing of the skeleton. In Ageing - General Aspects, Ciba Foundation Colloquia on Ageing, pp. 109-125 [GEW Wolstenholme and MR Cameron, editors]. Boston: Little, Brown.
27. 3 in intact animals. Endocrinology 140, 2224-2231.
28. National Research Council (1996) Guide for the care and use of laboratory animals. National Academy Press, Washington D.C.
29. Nesbitt T & Drezner MK (1993) Insulin-like growth factor-I regulation of renal 25-hydroxyvitamin D-1-hydroxylase activity. Endocrinology 132, 133-138.
30. Pike JW, Spanos E, Colston KW, Macintyre I & Haussler MR (1978) Influence of estrogen on renal vitamin D hydroxylases and serum 1alpha,25-(OH)2D3 in chicks. Am J Physiol 235, E338-E343.
31. 3. Endocrinology 137, 2938-2946.
32. Shimada T, Hasegawa H, Yamazaki Y, Muto T, Hino R, Takeuchi Y, Fujita T, Nakahara K, Fukumoto S & Yamashita T (2004) FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis. J Bone Miner Res 19, 429-435.
33. Spanos E, Barrett D, MacIntyre I, Pike JW, Safilian WF & Haussler MR (1978) Effect of growth hormone on vitamin D metabolism. Nature 273, 246-247.
34. Tanaka Y & Deluca HF (1975) The control of 25-hydroxyvitamin D metabolism by inorganic phosphorus. Arch Biochem Biophys 154, 566-574.
35. Takeda E, Yamamoto H, Nashiki K, Sato T, Arai H & Taketani Y (2004) Inorganic phosphate homeostasis and the role of dietary phosphorus. J Cell Mol Med 8, 191-200.
36. Tenenhouse HS, Martel J, Gauthier C, Zhang MYH & Portale AA (2001) Renal expression of the sodium/phosphate cotransporter gene, Npt2, is not required for regulation of renal 1a-hydroxylase by phosphate. Endocrinology 142, 1124-1129.
37. Tsai KS, Heath HIII, Kumar R & Riggs BL (1984) Impaired vitamin D metabolism with aging in women. Possible role in pathogenesis of senile osteoporosis. J Clin Invest 73, 1668-1672.
38. Wilz DR, Gray RW, Dominguez JH & Lemann J Jr (1979) Plasma 1,25-(OH)2-vitamin D concentrations and net intestinal calcium, phosphate, and magnesium absorption in humans. Am J Clin Nutr 10, 2052-2060.
39. 3 biosynthesis during low-P diet in adult rats. Am J Physiol 272, F698-F703.
40. Wong MS, Tembe VA & Favus MJ (2000) Insulin-like growth factor-I stimulates renal 1,25-dihydroxycholecalciferol synthesis in old rats fed a low calcium diet. J Nutr 130, 1147-1152.
41. Wu S, Finch J, Zhong M, Slatopolsky E, Grieff M & Brown AJ (1996) Expression of the renal 25-hydroxyvitamin D-24-hydroxylase gene: regulation by dietary phosphate. Am J Physiol 271, F203-F208.
42. 3 1α-hydroxylase gene expression. Endocrinology 142, 1720-1726.
43. Zhang MYH, Wang X, Wang JT, Compagnone NA, Mellon SH, Olson JL, Tenenhouse HS, Miller WL & Portale AA (2002) Dietary phosphorus transcriptionally regulates 25-hydroxyvitamin D-1α-hydroxylase gene expression in the proximal renal tubule. Endocrinology 143, 587-595.