An evolutionary conserved motif is responsible for Immunoglobulin heavy chain packing in the B cell membrane

Molecular Phylogenetics and Evolution

Volumn 57, Issue 3, 2010, Pages 1238-1244

  Varriale, Sonia ^a,b   Merlino, Antonello ^b,c   Coscia, Maria Rosaria ^a   Mazzarella, Lelio ^b,c   Oreste, Umberto ^a  

^a INSTITUTE OF PROTEIN BIOCHEMISTRY   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c CNR   (Italy)

Author keywords

Immunoglobulin evolution; Immunoglobulin heavy chain; Immunoglobulin isotypes; Molecular dynamics; POPC lipid bilayer; Purifying selection; Transmembrane helix

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; B LYMPHOCYTE; CHEMICAL STRUCTURE; COMPUTER SIMULATION; GENETIC SELECTION; GENETICS; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYLOGENY; PROTEIN TERTIARY STRUCTURE; SEQUENCE ANALYSIS; VERTEBRATE;

AMINO ACID SEQUENCE; ANIMALS; B-LYMPHOCYTES; COMPUTER SIMULATION; CONSERVED SEQUENCE; IMMUNOGLOBULIN HEAVY CHAINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; SELECTION, GENETIC; SEQUENCE ANALYSIS, PROTEIN; VERTEBRATES;

CHONDRICHTHYES; MAMMALIA; VERTEBRATA;

EID: 78649661317     PISSN: 10557903     EISSN: 10959513     Source Type: Journal    
DOI: 10.1016/j.ympev.2010.09.022     Document Type: Article

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