Pigment epithelium-derived factor protects cultured retinal neurons against hydrogen peroxide-induced cell death

Journal of Neuroscience Research

Volumn 57, Issue 6, 1999, Pages 789-800

  Cao, W ^a,c   Tombran Tink, J ^b   Chen, W ^a   Mrazek, D ^b   Elias, R ^a   McGinnis, J F ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

Apoptosis; Basic fibroblast growth factor; Brain derived neurotrophic factor; Ciliary neurotrophic factor; Cytotoxicity; Hydrogen peroxide; Photoreceptors; Pigment epithelium derived factor; Retinal neuronal culture

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CILIARY NEUROTROPHIC FACTOR; FIBROBLAST GROWTH FACTOR; GLUTAMIC ACID; HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; NEUROTROPHIC FACTOR; TETRAZOLIUM;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO DEVELOPMENT; IMMUNOCYTOCHEMISTRY; NERVE CELL DIFFERENTIATION; NEUROPROTECTION; NONHUMAN; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RAT; RETINA DEGENERATION; RETINA NERVE CELL;

ANIMALS; APOPTOSIS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DEATH; CELLS, CULTURED; CILIARY NEUROTROPHIC FACTOR; EYE PROTEINS; FIBROBLAST GROWTH FACTOR 2; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RETINA; SERPINS;

EID: 0033568388     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19990915)57:6<789::AID-JNR4>3.0.CO;2-M     Document Type: Article

References (46)

1. Araki T, Taniwaki T, Becerra SP, Chader GJ, Schwartz JP. 1998. Pigment epithelium-derived factor (PEDF) differentially protects immature but not mature cerebellar granule cells against apoptotic cell death. J Neurosci Res 53:7-15.
2. Becker E, Soler RM, Yuste VJ, Gine E, Sanz-Rodriguez C, Egea J, Martin-Zanca D, Comella JX. 1998. Development of survival responsiveness to brain-derived neurotrophic factor, neurotrophin 3 and neurotrophin 4/5, but not to nerve growth factor, in cultured motoneurons from chick embryo spinal cord. J Neurosci 18:7903-7911.
3. Berglin L, Algvere PV, Seregard S. 1997. Photoreceptor decay over time and apoptosis in experimental retinal detachment. Graefes Arch Clin Exp Ophthalmol 235:306-312.
4. Blanks JC, Pickford MS, Organisciak DT. 1992. Ascorbate treatment prevents accumulation of phagosomes in RPE in light damage. Invest Ophthalmol Vis Sci 33:2814-2821.
5. Bottenstein J, Hayashi I, Hutchings S, Masui H, Mather J, McClure DB, Ohasa S, Rizzino A, Sato G, Serrero G, Wolfe R, Wu R. 1979. The growth of cells in serum-free hormone-supplemented media. Methods Enzymol 58:94-109.
6. Cao W, Wen R, Li F, Cheng T, Steinberg RH. 1997. Induction of basic fibroblast growth factor mRNA by basic fibroblast growth factor in Muller cells. Invest Ophthalmol Vis Sci 38:1358-1366.
7. Chang JY, Liu LZ. 1998. Toxicity of cholesterol oxides on cultured neuroretinal cells. Curr Eye Res 17:95-103.
8. Clement MV, Ponton A, Pervaiz S. 1998. Apoptosis induced by hydrogen peroxide is mediated by decreased superoxide anion concentration and reduction of intracellular milieu. FEBS Lett 440:13-18.
9. Faktorovich EG, Steinberg RH, Yasumura D, Matthes MT, LaVail MM. 1990. Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor. Nature 347:83-86.
10. Gao H, Qiao X, Hefti F, Hollyfield JG, Knusel B. 1997. Elevated mRNA expression of brain-derived neurotrophic factor in retinal ganglion cell layer after optic nerve injury. Invest Ophthalmol Vis Sci 38:1840-1847.
11. Goliath R, Tombran-Tink J, Rodriquez IR, Chader G, Ramesar R, Greenberg J. 1996. The gene for PEDF, a retinal growth factor is a prime candidate for retinitis pigmentosa and is tightly linked to the RP13 locus on chromosome 17p13.3. Mol Vis 2:5:5
12. Gupta SK, Jollimore CA, McLaren MJ, Inana G, Kelly ME. 1997. Mammalian retinal pigment epithelial cells in vitro respond to the neurokines ciliary neurotrophic factor and leukemia inhibitory factor. Biochem Cell Biol 75:119-125.
13. Halliwell B. 1992. Reactive oxygen species and the central nervous system. J Neurochem 59:1609-1623.
14. Hivert B, Cerruti C, Camu W. 1998. Hydrogen peroxide-induced motoneuron apoptosis is prevented by poly ADP ribosyl synthetase inhibitors. NeuroReport 9:1835-1838.
15. Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ. 1993. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75:241-251.
16. Iwata E, Miyazaki I, Asanuma M, Iida A, Ogawa N. 1998. Protective effects of nicergoline against hydrogen peroxide toxicity in rat neuronal cell line. Neurosci Lett 251:49-52.
17. 2-induced apoptosis in PC12 cells by glutathione independent mechanism. Neurosci Lett 212:179-182.
18. Kerrigan LA, Zack DJ, Quigley HA, Smith SD, Pease ME. 1997. TUNEL-positive ganglion cells in human primary open-angle glaucoma. Arch Ophthalmol 115:1031-1035.
19. Kitamura Y, Ota T, Matsuoka Y, Tooyama I, Kimura H, Shimohama S, Nomura Y, Gebicke-Haerter PJ, Taniguchi T. 1999. Hydrogen peroxide-induced apoptosis mediated by p53 protein in glial cells. Glia 25:154-164.
20. LaVail MM, Unoki K, Yasumura D, Matthes MT, Yancopoulos GD, Steinberg RH. 1992. Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light. Proc Natl Acad Sci USA 89:11249-11253.
21. Lenaz G, Cavazzoni M, Genova ML, D'Aurelio M, Pich MM, Pallotti F, Formiggini G, Marchetti M, Castelli GP, Bovina C. 1998. Oxidative stress, antioxidant defences and aging. Biofactors 8:195-204.
22. Lillien L, Cepko C. 1992. Control of proliferation in the retina: temporal changes in responsiveness to FGF and TGF alpha. Development 115:253-266.
23. Madesh M, Benard O, Balasubramanian KA. 1999. Apoptotic process in the monkey small intestinal epithelium: 2. Possible role of oxidative stress. Free Rad Biol Med 26:431-438.
24. Malchiodi-Albedi F, Feher J, Caiazza S, Formisano G, Perilli R, Falchi M, Petrucci TC, Scorcia G, Tombran-Tink J. 1998. PEDF (pigment epithelium-derived factor) promotes increase and maturation of pigment granules in pigment epithelial cells in neonatal albino rat retinal cultures. Int J Dev Neurosci 16:423-432.
25. McGinnis JF, Stepanik PL, Chen W, Elias R, Cao W, Lerious V. 1999. Unique retina cell phenotypes revealed by immunological analysis of recoverin expression in rat retina cells. J Neurosci Res 55:252-260.
26. Organisciak DT, Darrow RM, Barsalou L, Darrow RA, Kutty RK, Kutty G, Wiggert B. 1998. Light history and age-related changes in retinal light damage. Invest Ophthalmol Vis Sci 39:1107-1116.
27. Ramachandran S, Morris SM, Devamanoharan P, Henein M, Varma SD. 1991. Radio-isotopic determination of hydrogen peroxide in aqueous humor and urine. Exp Eye Res 53:503-506.
28. Reme CE, Grimm C, Hafezi F, Marti A, Wenzel A. 1998. Apoptotic cell death in retinal degenerations. Prog Retina Eye Res 17:443-464.
29. Rosenbaum DM, Rosenbaum PS, Gupta A, Michaelson MD, Hall DH, Kessler JA. 1997. Retinal ischemia leads to apoptosis which is ameliorated by aurintricarboxylic acid. Vis Res 37:3445-3451.
30. Seigel GM, Tombran-Tink J, Becerra SP, Chader GJ, Diloreto DAJ, del Cerro C, Lazar ES, del Cerro M. 1994. Differentiation of Y79 retinoblastoma cells with pigment epithelial-derived factor and interphotoreceptor matrix wash: effects on tumorigenicity. Growth Factors 10:289-297.
31. Skaper SD, Floreani M, Negro A, Facci L, Giusti P. 1998. Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway. J Neurochem 70:1859-1868.
32. 2. Invest Ophthalmol Vis Sci 39:1188-1197.
33. Steele FR, Chader OJ, Johnson LV, Tombran-Tink J. 1993. Pigment epithelium-derived factor: neurotrophic activity and identification as a member of the serine protease inhibitor gene family. Proc Natl Acad Sci USA 90:1526-1530.
34. Stoyanovsky DA, Goldman R, Darrow RM, Organisciak DT, Kagan VE. 1995. Endogenous ascorbate regenerates vitamin E in the retina directly and in combination with exogenous dihydrolipoic acid. Curr Eye Res 14:181-189.
35. Taguchi H, Ogura Y, Takanashi T, Hashizoe M, Honda Y. 1996. In vivo quantitation of peroxides in the vitreous humor by fluorophotometry. Invest Ophthalmol Vis Sci 37:1444-1450.
36. Tan S, Wood M, Maher P. 1998. Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells. J Neurochem 71:95-105.
37. Taniwaki T, Becerra SP, Chader GJ, Schwartz JP. 1995. Pigment epithelium-derived factor is a survival factor for cerebellar granule cells in culture. J Neurochem 64:2509-2517.
38. Taniwaki T, Hirashima N, Becerra SP, Chader GJ, Etcheberrigaray R, Schwartz JP. 1997. Pigment epithelium-derived factor protects cultured cerebellar granule cells against glutamate-induced neurotoxicity. J Neurochem 68:26-32.
39. Tombran-Tink J, Chader GG, Johnson LV. 1991. PEDF: a pigment epithelium-derived factor with potent neuronal differentiative activity [letter]. Exp Eye Res 53:411-414.
40. Tombran-Tink J, Pawar H, Swaroop A, Rodriguez I, Chader GJ. 1994. Localization of the gene for pigment epithelium-derived factor (PEDF) to chromosome 17p13.1 and expression in cultured human retinoblastoma cells. Genomics 19:266-272.
41. Tombran-Tink J, Shivaram SM, Chader GJ, Johnson LV, Bok D. 1995. Expression, secretion, and age-related downregulation of pigment epithelium-derived factor, a serpin with neurotrophic activity. J Neurosci 15:4992-5003.
42. Tombran-Tink J, Mazuruk K, Rodriguez IR, Chung D, Linker T, Englander E, Chader GJ. 1996. Organization, evolutionary conservation, expression and unusual Alu density of the human gene for pigment epithelium-derived factor, a unique neurotrophic serpin. Mol Vis 2:11:11
43. Travis GH. 1998. Mechanisms of cell death in the inherited retinal degenerations. Am J Hum Genet 62:503-508.
44. Weibel D, Kreutzberg GW, Schwab ME. 1995. Brain-derived neurotrophic factor (BDNF) prevents lesion-induced axonal die-back in young rat optic nerve. Brain Res 679:249-254.
45. Yamashita H, Horie K, Yamamoto T, Nagano T, Hirano T. 1992. Light-induced retinal damage in mice. Hydrogen peroxide production and superoxide dismutase activity in retina. Retina 12:59-66.
46. 2-induced apoptosis in human neuronal cells. Biochem Biophys Res Commun 235:845-848.