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Volumn 120, Issue 25, 2009, Pages 2567-2576

Endothelial estrogen receptor-α plays a crucial role in the atheroprotective action of 17β-estradiol in low-density lipoprotein receptor-deficient mice

Author keywords

Atherosclerosis; Endothelium; Estrogens; Hormones; Receptors

Indexed keywords

ANGIOPOIETIN RECEPTOR; CRE RECOMBINASE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; LOW DENSITY LIPOPROTEIN RECEPTOR; INTEGRASE; PROTEIN TYROSINE KINASE; TEK PROTEIN, MOUSE;

EID: 73949135461     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.109.898445     Document Type: Article
Times cited : (98)

References (46)
  • 4
    • 0035571660 scopus 로고    scopus 로고
    • Hormone replacement therapy and endothelial function: The exception that proves the rule?
    • Vita JA, Keaney JF Jr. Hormone replacement therapy and endothelial function: the exception that proves the rule? Arterioscler Thromb Vasc Biol. 2001;21:1867-1869.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1867-1869
    • Vita, J.A.1    Keaney Jr, J.F.2
  • 5
    • 18844393948 scopus 로고    scopus 로고
    • Controversies about HRT: Lessons from monkey models
    • Clarkson TB, Appt SE. Controversies about HRT: lessons from monkey models. Maturitas. 2005;51:64-74.
    • (2005) Maturitas , vol.51 , pp. 64-74
    • Clarkson, T.B.1    Appt, S.E.2
  • 6
    • 0036801741 scopus 로고    scopus 로고
    • Estrogen inhibits the initiation of fatty streaks throughout the vasculature but does not inhibit intra-plaque hemorrhage and the progression of established lesions in apolipoprotein e deficient mice
    • Rosenfeld ME, Kauser K, Martin-McNulty B, Polinsky P, Schwartz SM, Rubanyi GM. Estrogen inhibits the initiation of fatty streaks throughout the vasculature but does not inhibit intra-plaque hemorrhage and the progression of established lesions in apolipoprotein E deficient mice. Atherosclerosis. 2002;164:251-259.
    • (2002) Atherosclerosis , vol.164 , pp. 251-259
    • Rosenfeld, M.E.1    Kauser, K.2    Martin-Mcnulty, B.3    Polinsky, P.4    Schwartz, S.M.5    Rubanyi, G.M.6
  • 8
    • 0035936528 scopus 로고    scopus 로고
    • Estradiol accelerates reendothelialization in mouse carotid artery through estrogen receptor-alpha but not estrogen receptor-beta
    • Brouchet L, Krust A, Dupont S, Chambon P, Bayard F, Arnal JF. Estradiol accelerates reendothelialization in mouse carotid artery through estrogen receptor-alpha but not estrogen receptor-beta. Circulation. 2001; 103:423-428.
    • (2001) Circulation , vol.103 , pp. 423-428
    • Brouchet, L.1    Krust, A.2    Dupont, S.3    Chambon, P.4    Bayard, F.5    Arnal, J.F.6
  • 10
    • 0027429548 scopus 로고
    • Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene
    • Lubahn DB, Moyer JS, Golding TS, Couse JF, Korach KS, Smithies O. Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene. Proc Natl Acad Sci USA. 1993;90:11162-11166.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11162-11166
    • Lubahn, D.B.1    Moyer, J.S.2    Golding, T.S.3    Couse, J.F.4    Korach, K.S.5    Smithies, O.6
  • 11
    • 0035132187 scopus 로고    scopus 로고
    • Estrogen receptor alpha is a major mediator of 17beta-estradiol's athero-protective effects on lesion size in Apoe\-/\-mice
    • Hodgin JB, Krege JH, Reddick RL, Korach KS, Smithies O, Maeda N. Estrogen receptor alpha is a major mediator of 17beta-estradiol's athero-protective effects on lesion size in Apoe\-/\-mice. J Clin Invest. 2001; 107:333-340.
    • (2001) J Clin Invest , vol.107 , pp. 333-340
    • Hodgin, J.B.1    Krege, J.H.2    Reddick, R.L.3    Korach, K.S.4    Smithies, O.5    Maeda, N.6
  • 12
    • 0033767836 scopus 로고    scopus 로고
    • Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes
    • Dupont S, Krust A, Gansmuller A, Dierich A, Chambon P, Mark M. Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes. Development. 2000;127:4277-4291.
    • (2000) Development , vol.127 , pp. 4277-4291
    • Dupont, S.1    Krust, A.2    Gansmuller, A.3    Dierich, A.4    Chambon, P.5    Mark, M.6
  • 14
    • 0033584721 scopus 로고    scopus 로고
    • The direct antiatherogenic effect of estrogen is present, absent, or reversed, depending on the state of the arterial endothelium: A time course study in cholesterol-clamped rabbits
    • Holm P, Andersen HL, Andersen MR, Erhardtsen E, Stender S. The direct antiatherogenic effect of estrogen is present, absent, or reversed, depending on the state of the arterial endothelium: a time course study in cholesterol-clamped rabbits. Circulation. 1999;100:1727-1733.
    • (1999) Circulation , vol.100 , pp. 1727-1733
    • Holm, P.1    Andersen, H.L.2    Andersen, M.R.3    Erhardtsen, E.4    Stender, S.5
  • 15
    • 0032945571 scopus 로고    scopus 로고
    • Protection against atherosclerosis by estrogen is independent of plasma cholesterol levels in LDL receptor-deficient mice
    • Marsh MM, Walker VR, Curtiss LK, Banka CL. Protection against atherosclerosis by estrogen is independent of plasma cholesterol levels in LDL receptor-deficient mice. J Lipid Res. 1999;40:893-900.
    • (1999) J Lipid Res , vol.40 , pp. 893-900
    • Marsh, M.M.1    Walker, V.R.2    Curtiss, L.K.3    Banka, C.L.4
  • 16
    • 52949118482 scopus 로고    scopus 로고
    • The multifaceted contributions of leukocyte subsets to atherosclerosis: Lessons from mouse models
    • Weber C, Zernecke A, Libby P. The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models. Nat Rev Immunol. 2008;8:802-815.
    • (2008) Nat Rev Immunol , vol.8 , pp. 802-815
    • Weber, C.1    Zernecke, A.2    Libby, P.3
  • 17
    • 33645891172 scopus 로고    scopus 로고
    • Cytokines in atherosclerosis: Pathogenic and regulatory pathways
    • Tedgui A, Mallat Z. Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol Rev. 2006;86:515-581.
    • (2006) Physiol Rev , vol.86 , pp. 515-581
    • Tedgui, A.1    Mallat, Z.2
  • 18
    • 34547792318 scopus 로고    scopus 로고
    • The complex role of estrogens in inflammation
    • Straub RH. The complex role of estrogens in inflammation. Endocr Rev. 2007;28:521-574.
    • (2007) Endocr Rev , vol.28 , pp. 521-574
    • Straub, R.H.1
  • 19
    • 0030901474 scopus 로고    scopus 로고
    • Estrogen-receptor-mediated inhibition of human endothelial cell apopto-sis: Estradiol as a survival factor
    • Spyridopoulos I, Sullivan AB, Kearney M, Isner JM, Losordo DW. Estrogen-receptor-mediated inhibition of human endothelial cell apopto-sis: estradiol as a survival factor. Circulation. 1997;95:1505-1514.
    • (1997) Circulation , vol.95 , pp. 1505-1514
    • Spyridopoulos, I.1    Sullivan, A.B.2    Kearney, M.3    Isner, J.M.4    Losordo, D.W.5
  • 22
    • 0035911253 scopus 로고    scopus 로고
    • Conditional vascular cell adhesion molecule 1 deletion in mice: Impaired lymphocyte migration to bone marrow
    • Koni PA, Joshi SK, Temann UA, Olson D, Burkly L, Flavell RA. Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrow. J Exp Med. 2001;193:741-754.
    • (2001) J Exp Med , vol.193 , pp. 741-754
    • Koni, P.A.1    Joshi, S.K.2    Temann, U.A.3    Olson, D.4    Burkly, L.5    Flavell, R.A.6
  • 24
    • 0037133190 scopus 로고    scopus 로고
    • The AF-1 activation-function of ERalpha may be dispensable to mediate the effect of estradiol on endothelial NO production in mice
    • Pendaries C, Darblade B, Rochaix P, Krust A, Chambon P, Korach KS, Bayard F, Arnal JF. The AF-1 activation-function of ERalpha may be dispensable to mediate the effect of estradiol on endothelial NO production in mice. Proc Natl Acad Sci USA. 2002;99:2205-2210.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 2205-2210
    • Pendaries, C.1    Darblade, B.2    Rochaix, P.3    Krust, A.4    Chambon, P.5    Korach, K.S.6    Bayard, F.7    Arnal, J.F.8
  • 26
    • 50949111554 scopus 로고    scopus 로고
    • Chronic estradiol administration in vivo promotes the proinflammatory response of macrophages to TLR4 activation: Involvement of the phosphatidylinositol 3-kinase pathway
    • Calippe B, Douin-Echinard V, Laffargue M, Laurell H, Rana-Poussine V, Pipy B, Guery JC, Bayard F, Arnal JF, Gourdy P. Chronic estradiol administration in vivo promotes the proinflammatory response of macrophages to TLR4 activation: involvement of the phosphatidylinositol 3-kinase pathway. J Immunol. 2008;180:7980-7988.
    • (2008) J Immunol , vol.180 , pp. 7980-7988
    • Calippe, B.1    Douin-Echinard, V.2    Laffargue, M.3    Laurell, H.4    Rana-Poussine, V.5    Pipy, B.6    Guery, J.C.7    Bayard, F.8    Arnal, J.F.9    Gourdy, P.10
  • 27
    • 28844476756 scopus 로고    scopus 로고
    • Bone marrow dysfunction in mice lacking the cytokine receptor gp130 in endothelial cells
    • Yao L, Yokota T, Xia L, Kincade PW, McEver RP. Bone marrow dysfunction in mice lacking the cytokine receptor gp130 in endothelial cells. Blood. 2005;106:4093-4101.
    • (2005) Blood , vol.106 , pp. 4093-4101
    • Yao, L.1    Yokota, T.2    Xia, L.3    Kincade, P.W.4    McEver, R.P.5
  • 29
    • 0035015769 scopus 로고    scopus 로고
    • Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line
    • Constien R, Forde A, Liliensiek B, Grone HJ, Nawroth P, Hammerling G, Arnold B. Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line. Genesis. 2001;30:36-44.
    • (2001) Genesis , vol.30 , pp. 36-44
    • Constien, R.1    Forde, A.2    Liliensiek, B.3    Grone, H.J.4    Nawroth, P.5    Hammerling, G.6    Arnold, B.7
  • 30
    • 0030610152 scopus 로고    scopus 로고
    • Significant reduction of the antiatherogenic effect of estrogen by long-term inhibition of nitric oxide synthesis in cholesterol-clamped rabbits
    • Holm P, Korsgaard N, Shalmi M, Andersen HL, Hougaard P, Skouby SO, Stender S. Significant reduction of the antiatherogenic effect of estrogen by long-term inhibition of nitric oxide synthesis in cholesterol-clamped rabbits. J Clin Invest. 1997;100:821-828.
    • (1997) J Clin Invest , vol.100 , pp. 821-828
    • Holm, P.1    Korsgaard, N.2    Shalmi, M.3    Andersen, H.L.4    Hougaard, P.5    Skouby, S.O.6    Stender, S.7
  • 32
    • 0029079926 scopus 로고
    • Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein e
    • Smith JD, Trogan E, Ginsberg M, Grigaux C, Tian J, Miyata M. Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E. Proc Natl Acad Sci USA. 1995;92:8264-8268.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8264-8268
    • Smith, J.D.1    Trogan, E.2    Ginsberg, M.3    Grigaux, C.4    Tian, J.5    Miyata, M.6
  • 34
    • 0030711556 scopus 로고    scopus 로고
    • Prevention of fatty streak formation of 17beta-estradiol is not mediated by the production of nitric oxide in apolipoprotein E-deficient mice
    • Elhage R, Bayard F, Richard V, Holvoet P, Duverger N, Fievet C, Arnal JF. Prevention of fatty streak formation of 17beta-estradiol is not mediated by the production of nitric oxide in apolipoprotein E-deficient mice. Circulation. 1997;96:3048-3052.
    • (1997) Circulation , vol.96 , pp. 3048-3052
    • Elhage, R.1    Bayard, F.2    Richard, V.3    Holvoet, P.4    Duverger, N.5    Fievet, C.6    Arnal, J.F.7
  • 36
    • 0033588352 scopus 로고    scopus 로고
    • Estradiol inhibits leukocyte adhesion and transendothelial migration in rabbits in vivo: Possible mechanisms for gender differences in atherosclerosis
    • Nathan L, Pervin S, Singh R, Rosenfeld M, Chaudhuri G. Estradiol inhibits leukocyte adhesion and transendothelial migration in rabbits in vivo: possible mechanisms for gender differences in atherosclerosis. Circ Res. 1999;85:377-385.
    • (1999) Circ Res , vol.85 , pp. 377-385
    • Nathan, L.1    Pervin, S.2    Singh, R.3    Rosenfeld, M.4    Chaudhuri, G.5
  • 39
    • 0030901474 scopus 로고    scopus 로고
    • Estrogen-receptor-mediated inhibition of human endothelial cell apopto-sis: Estradiol as a survival factor
    • Spyridopoulos I, Sullivan AB, Kearney M, Isner JM, Losordo DW. Estrogen-receptor-mediated inhibition of human endothelial cell apopto-sis: estradiol as a survival factor. Circulation. 1997;95:1505-1514.
    • (1997) Circulation , vol.95 , pp. 1505-1514
    • Spyridopoulos, I.1    Sullivan, A.B.2    Kearney, M.3    Isner, J.M.4    Losordo, D.W.5
  • 40
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: A double-edged sword
    • Hansson GK, Libby P. The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol. 2006;6:508-519.
    • (2006) Nat Rev Immunol , vol.6 , pp. 508-519
    • Hansson, G.K.1    Libby, P.2
  • 43
    • 0346157997 scopus 로고    scopus 로고
    • Estrogen-mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow-derived endo-thelial progenitor cells contributes to reendothelialization after arterial injury
    • Iwakura A, Luedemann C, Shastry S, Hanley A, Kearney M, Aikawa R, Isner JM, Asahara T, Losordo DW. Estrogen-mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow-derived endo-thelial progenitor cells contributes to reendothelialization after arterial injury. Circulation. 2003;108:3115-3121.
    • (2003) Circulation , vol.108 , pp. 3115-3121
    • Iwakura, A.1    Luedemann, C.2    Shastry, S.3    Hanley, A.4    Kearney, M.5    Aikawa, R.6    Isner, J.M.7    Asahara, T.8    Losordo, D.W.9
  • 44
  • 45
    • 0035687170 scopus 로고    scopus 로고
    • The past, present, and future of selective estrogen receptor modulation
    • Jordan VC. The past, present, and future of selective estrogen receptor modulation. Ann N Y Acad Sci. 2001;949:72-79.
    • (2001) Ann N y Acad Sci , vol.949 , pp. 72-79
    • Jordan, V.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.