Effect of duramycin on chloride transport and intracellular calcium concentration in cystic fibrosis and non-cystic fibrosis epithelia

APMIS

Volumn 118, Issue 12, 2010, Pages 982-990

  Oliynyk, Igor ^a,b   Varelogianni, Georgia ^a,b   Roomans, Godfried M ^a   Johannesson, Marie ^a,c  

^a ÖREBRO UNIVERSITY HOSPITAL   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Airway epithelium; Chloride efflux; Cystic fibrosis; Duramycin; Intracellular calcium

Indexed keywords

CALCIUM; DURAMYCIN; GADOLINIUM CHLORIDE;

ARTICLE; BRONCHUS MUCOSA; CALCIUM CELL LEVEL; CHLORIDE TRANSPORT; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG ANTAGONISM; DRUG CHOICE; DRUG MECHANISM; EPITHELIUM CELL; HUMAN; HUMAN CELL; PANCREAS CELL; PRIORITY JOURNAL;

BACTERIOCINS; CALCIUM; CELL LINE; CHLORIDES; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EPITHELIAL CELLS; HUMANS; ION TRANSPORT; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; PEPTIDES;

EID: 78649506897     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/j.1600-0463.2010.02680.x     Document Type: Article

References (33)

1. Ratjen F, Doring G. Cystic fibrosis. Lancet 2003;361:681-9.
2. Clunes MT, Boucher RC. Front-runners for pharmacotherapeutic correction of the airway ion transport defect in cystic fibrosis. Curr Opin Pharmacol 2008;8:292-9.
3. Ratjen F. New pulmonary therapies for cystic fibrosis. Curr Opin Pulm Med 2007;13:541-6.
4. Shotwell OL, Stodola FH, Michael WR, Lindenfelser LA, Dworschack RG, Pridham TG. Antibiotics against plant disease. III. Duramycin, a new antibiotic from Streptomyces cinnamomeus forma azacoluta2. J Am Chem Soc 1958;80:3912-15.
5. Cloutier MM, Guernsey L, Mattes P, Koeppen B. Duramycin enhances chloride secretion in airway epithelium. Am J Physiol 1990;259(3 Pt 1):C450-4.
6. Zeitlin PL, Boyle MP, Guggino WB, Molina L. A phase I trial of intranasal Moli1901 for cystic fibrosis. Chest 2004;125:143-9.
7. Cloutier MM, Guernsey L, Sha'afi RI. Duramycin increases intracellular calcium in airway epithelium. Membr Biochem 1993;10:107-18.
8. Roberts M, Hladky SB, Pickles RJ, Cuthbert AW. Stimulation of sodium transport by duramycin in cultured human colonic epithelia. J Pharmacol Exp Ther 1991;259:1050-8.
9. Navarro J, Chabot J, Sherrill K, Aneja R, Zahler SA, Racker E. Interaction of duramycin with artificial and natural membranes. Biochemistry 1985;24:4645-50.
10. Chen L, Tai PC. Effects of antibiotics and other inhibitors on ATP-dependent protein translocation into membrane vesicles. J Bacteriol 1987;169:2373-9.
11. McNulty MJ, Hutabarat RH, Findlay JW, Devereux K, Knick VC, Harvey RJ, et al. Pharmacokinetics and tissue distribution of the nonadecapeptide Moli1901 in rats and mice. Xenobiotica 2003;33:197-210.
12. Grasemann H, Stehling F, Brunar H, Widmann R, Laliberte TW, Molina L, et al. Inhalation of Moli1901 in patients with cystic fibrosis. Chest 2007;131:1461-6.
13. Steiner I, Errhalt P, Kubesch K, Hubner M, Holy M, Bauer M, et al. Pulmonary pharmacokinetics and safety of nebulized duramycin in healthy male volunteers. Naunyn Schmiedebergs Arch Pharmacol 2008;378:323-33.
14. Zebedin E, Koenig X, Radenkovic M, Pankevych H, Todt H, Freissmuth M, et al. Effects of duramycin on cardiac voltage-gated ion channels. Naunyn Schmiedebergs Arch Pharmacol 2008;377:87-100.
15. Munkonge F, Alton EW, Andersson C, Davidson H, Dragomir A, Edelman A, et al. Measurement of halide efflux from cultured and primary airway epithelial cells using fluorescence indicators. J Cyst Fibros 2004;3(Suppl 2):171-6.
16. Gee KR, Brown KA, Chen WN, Bishop-Stewart J, Gray D, Johnson I. Chemical and physiological characterization of fluo-4 Ca(2+)-indicator dyes. Cell Calcium 2000;27:97-106.
17. Ma T, Thiagarajah JR, Yang H, Sonawane ND, Folli C, Galietta LJ, et al. Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion. J Clin Invest 2002;110:1651-8.
18. 2+ entry mechanism in rat A7r5 smooth muscle cells stimulated with low concentrations of vasopressin. J Physiol 1999;517:121-34.
19. Pressman BC. Biological applications of ionophores. Annu Rev Biochem 1976;45:501-30.
20. 2+-activated K+ channel in human airway Calu-3 cells. Am J Respir Cell Mol Biol 2004;30:388-95.
21. Oliynyk I, Varelogianni G, Schalling M, Asplund MS, Roomans GM, Johannesson M. Azithromycin increases chloride efflux from cystic fibrosis airway epithelial cells. Exp Lung Res 2009;35:210-21.
22. Anderson MP, Gregory RJ, Thompson S, Souza DW, Paul S, Mulligan RC, et al. Demonstration that CFTR is a chloride channel by alteration of its anion selectivity. Science 1991;253:202-5.
23. Petersen OH. Stimulus-secretion coupling: cytoplasmic calcium signals and the control of ion channels in exocrine acinar cells. J Physiol 1992;448:1-51.
24. Kalin N, Claass A, Sommer M, Puchelle E, Tummler B. DeltaF508 CFTR protein expression in tissues from patients with cystic fibrosis. J Clin Invest 1999;103:1379-89.
25. Frizzell RA, Rechkemmer G, Shoemaker RL. Altered regulation of airway epithelial cell chloride channels in cystic fibrosis. Science 1986;233:558-60.
26. Winpenny JP, Harris A, Hollingsworth MA, Argent BE, Gray MA. Calcium-activated chloride conductance in a pancreatic adenocarcinoma cell line of ductal origin (HPAF) and in freshly isolated human pancreatic duct cells. Pflugers Arch 1998;435:796-803.
27. Nakamura S, Racker E. Inhibitory effect of duramycin on partial reactions catalyzed by (Na+, K+)-adenosinetriphosphatase from dog kidney. Biochemistry 1984;23:385-9.
28. Iwamoto K, Hayakawa T, Murate M, Makino A, Ito K, Fujisawa T, et al. Curvature-dependent recognition of ethanolamine phospholipids by duramycin and cinnamycin. Biophys J 2007;93:1608-19.
29. Matsunaga S, Matsunaga T, Iwamoto K, Yamada T, Shibayama M, Kawai M, et al. Visualization of phospholipid particle fusion induced by duramycin. Langmuir 2009;25:8200-7.
30. Sheth TR, Henderson RM, Hladky SB, Cuthbert AW. Ion channel formation by duramycin. Biochim Biophys Acta 1992;1107:179-85.
31. Racker E, Riegler C, Abdel-Ghany M. Stimulation of glycolysis by placental polypeptides and inhibition by duramycin. Cancer Res 1984;44:1364-7.
32. Weibel ER, Gomez DM. Architecture of the human lung. Use of quantitative methods establishes fundamental relations between size and number of lung structures. Science 1962;137:577-85.
33. Tarran R. Regulation of airway surface liquid volume and mucus transport by active ion transport. Proc Am Thorac Soc 2004;1:42-6.