Activin A induces a non-fibrotic phenotype in smooth muscle cells in contrast to TGF-β

Experimental Cell Research

Volumn 317, Issue 2, 2011, Pages 131-142

  Groenendijk, Bianca C W ^a,c   Benus, Germaine F J D ^a   Klous, Anita ^a   Pacheco, Yolanda M ^a,d   Volger, Oscar L ^a   Fledderus, Joost O ^a,f   Ferreira, Valerie ^a   Engelse, Marten A ^a   Pannekoek, Hans ^a   ten Dijke, Peter ^b   Horrevoets, Anton J G ^a,e   de Vries, Carlie J M ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d INSTITUTO DE LA GRASA   (Spain)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^f UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Activin A; Extracellular matrix; Smad1; Smad2; Transforming growth factor (TGF ); Vascular smooth muscle cells

Indexed keywords

ACTIVIN A; ACTIVIN RECEPTOR LIKE KINASE 1; ACTIVIN RECEPTOR LIKE KINASE 4; CD51 ANTIGEN; CELL SURFACE RECEPTOR; COLLAGEN; ENDOGLIN; FIBRONECTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN SERINE THREONINE KINASE; SMAD PROTEIN; SMAD1 PROTEIN; SMAD2 PROTEIN; TRANSCRIPTOME; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

AORTA; ARTICLE; CELL DIFFERENTIATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; EXTRACELLULAR MATRIX; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MICROARRAY ANALYSIS; MOLECULAR DYNAMICS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR LESION; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

EID: 78649463586     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2010.10.007     Document Type: Article

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