메뉴 건너뛰기




Volumn 152, Issue 1-3, 2009, Pages 1-7

Weight-dependent differential contribution of insulin secretion and clearance to hyperinsulinemia of obesity

Author keywords

Insulin secretion; Insulin resistance; Obesity

Indexed keywords

C PEPTIDE; GLUCOSE; INSULIN;

EID: 57249104708     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2008.10.008     Document Type: Article
Times cited : (27)

References (35)
  • 1
    • 0029037649 scopus 로고
    • Pathophysiology of insulin resistance in human disease
    • Reaven G.M. Pathophysiology of insulin resistance in human disease. Physiol Rev 75 (1995) 473-486
    • (1995) Physiol Rev , vol.75 , pp. 473-486
    • Reaven, G.M.1
  • 3
    • 0027434701 scopus 로고
    • Plasma insulin, C-peptide, and proinsulin concentrations in obese and nonobese individuals with varying degrees of glucose tolerance
    • Reaven G.M., Chen Y.D., Hollenbeck C.B., Sheu W.H., Ostrega D., and Polonsky K.S. Plasma insulin, C-peptide, and proinsulin concentrations in obese and nonobese individuals with varying degrees of glucose tolerance. J Clin Endocrinol Metab 76 (1993) 44-48
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 44-48
    • Reaven, G.M.1    Chen, Y.D.2    Hollenbeck, C.B.3    Sheu, W.H.4    Ostrega, D.5    Polonsky, K.S.6
  • 4
    • 17844403548 scopus 로고    scopus 로고
    • Differential association of basal and postprandial plasma ghrelin with leptin, insulin, and type 2 diabetes
    • Erdmann J., Lippl F., Wagenpfeil S., and Schusdziarra V. Differential association of basal and postprandial plasma ghrelin with leptin, insulin, and type 2 diabetes. Diabetes 54 (2005) 1371-1378
    • (2005) Diabetes , vol.54 , pp. 1371-1378
    • Erdmann, J.1    Lippl, F.2    Wagenpfeil, S.3    Schusdziarra, V.4
  • 5
    • 78651132915 scopus 로고
    • Excessive insulin response to glucose in obese subjects as measured by immunochemical assay
    • Karam J.H., Grodsky G.M., and Forsham P.H. Excessive insulin response to glucose in obese subjects as measured by immunochemical assay. Diabetes 12 (1963) 197-204
    • (1963) Diabetes , vol.12 , pp. 197-204
    • Karam, J.H.1    Grodsky, G.M.2    Forsham, P.H.3
  • 6
    • 0013990334 scopus 로고
    • Plasma insulin responses to glucose and tolbutamide of normal weight and obese diabetic and nondiabetic subjects
    • Perley M., and Kipnis D.M. Plasma insulin responses to glucose and tolbutamide of normal weight and obese diabetic and nondiabetic subjects. Diabetes 15 (1966) 867-874
    • (1966) Diabetes , vol.15 , pp. 867-874
    • Perley, M.1    Kipnis, D.M.2
  • 11
    • 73649168830 scopus 로고
    • Forearm metabolism in obesity and its response to intra-arterial insulin. Characterization of insulin resistance and evidence for adaptive hyperinsulinism
    • Rabinowitz D., and Zierler K.L. Forearm metabolism in obesity and its response to intra-arterial insulin. Characterization of insulin resistance and evidence for adaptive hyperinsulinism. J Clin Invest 41 (1962) 2173-2181
    • (1962) J Clin Invest , vol.41 , pp. 2173-2181
    • Rabinowitz, D.1    Zierler, K.L.2
  • 12
    • 0030884698 scopus 로고    scopus 로고
    • Insulin resistance and hypersecretion in obesity. European Group for the Study of Insulin Resistance (EGIR)
    • Ferrannini E., Natali A., Bell P., Cavallo-Perin P., Lalic N., and Mingrone G. Insulin resistance and hypersecretion in obesity. European Group for the Study of Insulin Resistance (EGIR). J Clin Invest 100 (1997) 1166-1173
    • (1997) J Clin Invest , vol.100 , pp. 1166-1173
    • Ferrannini, E.1    Natali, A.2    Bell, P.3    Cavallo-Perin, P.4    Lalic, N.5    Mingrone, G.6
  • 13
    • 0031154101 scopus 로고    scopus 로고
    • Alterations in the glucose-stimulated insulin secretory dose-response curve and in insulin clearance in nondiabetic insulin-resistant individuals
    • Jones C.N., Pei D., Staris P., Polonsky K.S., Chen Y.D., and Reaven G.M. Alterations in the glucose-stimulated insulin secretory dose-response curve and in insulin clearance in nondiabetic insulin-resistant individuals. J Clin Endocrinol Metab 82 (1997) 1834-1838
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1834-1838
    • Jones, C.N.1    Pei, D.2    Staris, P.3    Polonsky, K.S.4    Chen, Y.D.5    Reaven, G.M.6
  • 14
    • 0026776703 scopus 로고
    • Effect of body mass index and fat distribution on insulin sensitivity, secretion, and clearance in nonobese healthy men
    • Walton C., Godsland I.F., Proudler A.J., Felton C.V., and Wynn V. Effect of body mass index and fat distribution on insulin sensitivity, secretion, and clearance in nonobese healthy men. J Clin Endocrinol Metab 75 (1992) 170-175
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 170-175
    • Walton, C.1    Godsland, I.F.2    Proudler, A.J.3    Felton, C.V.4    Wynn, V.5
  • 15
    • 0020806693 scopus 로고
    • Hyperinsulinemia of obesity is due to decreased clearance of insulin
    • Meistas M.T., Margolis S., and Kowarski A.A. Hyperinsulinemia of obesity is due to decreased clearance of insulin. Am J Physiol 245 (1983) E155-E159
    • (1983) Am J Physiol , vol.245
    • Meistas, M.T.1    Margolis, S.2    Kowarski, A.A.3
  • 16
    • 0022624911 scopus 로고
    • Effects of massive obesity on insulin sensitivity and insulin clearance and the metabolic response to insulin as assessed by the euglycemic clamp technique
    • Zuniga-Guajardo S., Jimenez J., Angel A., and Zinman B. Effects of massive obesity on insulin sensitivity and insulin clearance and the metabolic response to insulin as assessed by the euglycemic clamp technique. Metabolism 35 (1986) 278-282
    • (1986) Metabolism , vol.35 , pp. 278-282
    • Zuniga-Guajardo, S.1    Jimenez, J.2    Angel, A.3    Zinman, B.4
  • 19
    • 0028851809 scopus 로고
    • Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee
    • Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee. World Health Organ Tech. Rep. Ser. 854 (1995) 368-369
    • (1995) World Health Organ Tech. Rep. Ser. , vol.854 , pp. 368-369
  • 20
    • 0021813187 scopus 로고
    • Homeostasis model assessment: insulin resistance and ß-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., and Turner R.C. Homeostasis model assessment: insulin resistance and ß-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1985) 412-419
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 21
    • 0018956367 scopus 로고
    • Prehepatic insulin production in man: kinetic analysis using peripheral connecting peptide behaviour
    • Eaton R.P., Allen R.C., Schade D.S., Erickson K.M., and Standefer J. Prehepatic insulin production in man: kinetic analysis using peripheral connecting peptide behaviour. J Clin Endocrinol Metab 51 (1980) 520-528
    • (1980) J Clin Endocrinol Metab , vol.51 , pp. 520-528
    • Eaton, R.P.1    Allen, R.C.2    Schade, D.S.3    Erickson, K.M.4    Standefer, J.5
  • 24
    • 0026504160 scopus 로고
    • Estimation of insulin secretion rates from C-peptide levels - comparison of individual and standard kinetic parameters for C-peptide clearance
    • Van Cauter E., Metrez F., Sturis J., and Polonsky K.S. Estimation of insulin secretion rates from C-peptide levels - comparison of individual and standard kinetic parameters for C-peptide clearance. Diabetes 41 (1992) 368-377
    • (1992) Diabetes , vol.41 , pp. 368-377
    • Van Cauter, E.1    Metrez, F.2    Sturis, J.3    Polonsky, K.S.4
  • 25
    • 0016764063 scopus 로고
    • Drug therapy: clinical pharmacokinetics
    • Greenblatt D.J., and Kochweser J. Drug therapy: clinical pharmacokinetics. N Engl J Med 293 (1975) 702-705
    • (1975) N Engl J Med , vol.293 , pp. 702-705
    • Greenblatt, D.J.1    Kochweser, J.2
  • 26
    • 0023836241 scopus 로고
    • Incretin effect due to increased secretion and decreased clearance of insulin in normal humans
    • Shuster L.T., Go V.L., Rizza R.A., O'Brien P.C., and Service F.J. Incretin effect due to increased secretion and decreased clearance of insulin in normal humans. Diabetes 37 (1988) 200-203
    • (1988) Diabetes , vol.37 , pp. 200-203
    • Shuster, L.T.1    Go, V.L.2    Rizza, R.A.3    O'Brien, P.C.4    Service, F.J.5
  • 28
    • 0023136220 scopus 로고
    • The kinetics of insulin in man. II. The role of the liver
    • Ferrannini E., and Cobelli C. The kinetics of insulin in man. II. The role of the liver. Diabetes Metab Rev 3 (1987) 364-375
    • (1987) Diabetes Metab Rev , vol.3 , pp. 364-375
    • Ferrannini, E.1    Cobelli, C.2
  • 29
    • 0024205602 scopus 로고
    • Reduction of insulin clearance during hyperglycemic clamp. Dose-response study in normal humans
    • Tillil H., Shapiro E.T., Rubenstein A.H., Galloway J.A., and Polonsky K.S. Reduction of insulin clearance during hyperglycemic clamp. Dose-response study in normal humans. Diabetes 37 (1988) 1351-1357
    • (1988) Diabetes , vol.37 , pp. 1351-1357
    • Tillil, H.1    Shapiro, E.T.2    Rubenstein, A.H.3    Galloway, J.A.4    Polonsky, K.S.5
  • 30
    • 0025761974 scopus 로고
    • Cellular trafficking and processing of the insulin receptor
    • Knutson V.P. Cellular trafficking and processing of the insulin receptor. FASEB J 5 (1991) 2130-2138
    • (1991) FASEB J , vol.5 , pp. 2130-2138
    • Knutson, V.P.1
  • 31
    • 20044368667 scopus 로고    scopus 로고
    • Pulsatile insulin secretion dictates systemic delivery by regulating hepatic insulin extraction in humans
    • Meier J.J., Veldhuis J.D., and Butler P.C. Pulsatile insulin secretion dictates systemic delivery by regulating hepatic insulin extraction in humans. Diabetes 54 (2005) 1649-1656
    • (2005) Diabetes , vol.54 , pp. 1649-1656
    • Meier, J.J.1    Veldhuis, J.D.2    Butler, P.C.3
  • 32
    • 34548389205 scopus 로고    scopus 로고
    • Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by glucagon-like peptide 1 or gastric inhibitory polypeptide in humans
    • Meier J.J., Holst J.J., Schmidt W.E., and Nauck M.A. Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by glucagon-like peptide 1 or gastric inhibitory polypeptide in humans. Am J Physiol Endocrinol Metab 293 (2007) E849-E856
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Meier, J.J.1    Holst, J.J.2    Schmidt, W.E.3    Nauck, M.A.4
  • 33
    • 0030008060 scopus 로고    scopus 로고
    • Fatty acids and insulin resistance (review)
    • Boden G. Fatty acids and insulin resistance (review). Diabetes Care 19 (1996) 394-395
    • (1996) Diabetes Care , vol.19 , pp. 394-395
    • Boden, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.