Thrombomodulin is upregulated in cardiomyocytes during cardiac hypertrophy and prevents the progression of contractile dysfunction

Journal of Cardiac Failure

Volumn 16, Issue 12, 2010, Pages 980-990

  Li, Yi Heng ^a   Chung, Hsing Chun ^a   Luo, Chawn Yau ^a   Chao, Ting Hsing ^a   Shyu, Kou Gi ^b   Shi, Guey Yueh ^a   Wu, Hua Lin ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cardiac hypertrophy; Heart failure; Thrombomodulin

Indexed keywords

ATRIAL NATRIURETIC FACTOR; DOXORUBICIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; RECOMBINANT THROMBOMODULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CONSTRICTION; APOPTOSIS; ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DISEASE COURSE; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CARDIOMEGALY; CARDIOTONIC AGENTS; CELLS, CULTURED; DISEASE PROGRESSION; HUMANS; MICE; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; RATS; RATS, WISTAR; THROMBOMODULIN; UP-REGULATION;

EID: 78649446628     PISSN: 10719164     EISSN: 15328414     Source Type: Journal    
DOI: 10.1016/j.cardfail.2010.06.415     Document Type: Article

References (31)

1. B.A. Vakili, P.M. Okin, and R.B. Devereux Prognostic implications of left ventricular hypertrophy Am Heart J 141 2001 334 341
2. E. Teiger, V.D. Than, L. Richard, C. Wisnewsky, B.S. Tea, and L. Gaboury Apoptosis in pressure overload-induced heart hypertrophy in the rat J Clin Invest 97 1996 2891 2897
3. G. Condorelli, C. Morisco, G. Stassi, A. Notte, F. Farina, and G. Sgaramella Increased cardiomyocyte apoptosis and changes in proapoptotic and antiapoptotic genes bax and bcl-2 during left ventricular adaptations to chronic pressure overload in the rat Circulation 99 1999 3071 3078
4. C.T. Esmon The roles of protein C and thrombomodulin in the regulation of blood coagulation J Biol Chem 264 1989 4743 4746
5. G. Tohda, K. Oida, Y. Okada, S. Kosaka, E. Okada, and S. Takahashi Expression of thrombomodulin in atherosclerotic lesions and mitogenic activity of recombinant thrombomodulin in vascular smooth muscle cells Arterioscler Thromb Vasc Biol 18 1998 1861 1869
6. J. Hu, I. Higuchi, M. Inose, T. Niiyama, Y. Uchida, and M. Osame Characteristic expression of thrombomodulin in the muscle sarcoplasm in patients with the acute phase of rhabdomyolysis Eur Neurol 43 2000 174 180
7. T. Suehiro, M. Shimada, T. Matsumata, A. Taketomi, K. Yamamoto, and K. Sugimachi Thrombomodulin inhibits intrahepatic spread in human hepatocellular carcinoma Hepatology 21 1995 1285 1290
8. A.M. Hanly, M. Redmond, D.C. Winter, S. Brophy, J.M. Deasy, and D.J. Bouchier-Hayes Thrombomodulin expression in colorectal carcinoma is protective and correlates with survival Br J Cancer 94 2006 1320 1325
9. H. Ishii, and P.W. Majerus Thrombomodulin is present in human plasma and urine J Clin Invest 76 1985 2178 2181
10. C.S. Shi, G.Y. Shi, Y.S. Chang, H.S. Han, C.H. Kuo, and C. Liu Evidence of human thrombomodulin domain as a novel angiogenic factor Circulation 111 2005 1627 1636
11. H. Hamada, H. Ishii, K. Sakyo, S. Horie, K. Nishiki, and M. Kazama The epidermal growth factor-like domain of recombinant human thrombomodulin exhibits mitogenic activity for Swiss 3T3 cells Blood 86 1995 225 233
12. Y.H. Li, C.Y. Hsieh, D.L. Wang, H.C. Chung, S.L. Liu, and T.H. Chao Remodeling of carotid arteries is associated with increased expression of thrombomodulin in a mouse transverse aortic constriction model Thromb Haemost 97 2007 658 664
13. B.W. Wang, H.F. Hung, H. Chang, P. Kuan, and K.G. Shyu Mechanical stretch enhances the expression of resistin gene in cultured cardiomyocytes via tumor necrosis factor-α Am J Physiol Heart Circ Physiol 293 2007 H2305 H2312
14. Y.H. Li, S.L. Liu, G.Y. Shi, G.H. Tseng, P.Y. Liu, and H.L. Wu Thrombomodulin plays an important role in arterial remodeling and neointima formation in mouse carotid ligation model Thromb Haemost 95 2006 128 133
15. L.E. Teichholz, T. Kreulen, M.V. Herman, and R. Gorlin Problems in echocardiographic volume determinations: echocardiographic-angiographic correlations in the presence of absence of asynergy Am J Cardiol 37 1976 7 11
16. B. Ding, R.L. Price, E.C. Goldsmith, T.K. Borg, X. Yan, and P.S. Douglas Left ventricular hypertrophy in ascending aortic stenosis mice: anoikis and the progression to early failure Circulation 101 2000 2854 2862
17. S. Hein, E. Arnon, S. Kostin, M. Schönburg, A. Elsässer, and V. Polyakova Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: structural deterioration and compensatory mechanisms Circulation 107 2003 984 991
18. T. Ozaki, C. Anas, S. Maruyama, T. Yamamoto, K. Yasuda, and Y. Morita Intrarenal administration of recombinant human soluble thrombomodulin ameliorates ischaemic acute renal failure Nephrol Dial Transplant 23 2008 110 119
19. B.W. Festoff, S. Ameenuddin, K. Santacruz, J. Morser, Z. Suo, and P.M. Arnold Neuroprotective effects of recombinant thrombomodulin in controlled contusion spinal cord injury implicates thrombin signaling J Neurotrauma 21 2004 907 922
20. A. Leri, P.P. Claudio, Q. Li, A. Leri, P.P. Claudio, and Q. Li Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the bcl-2-to-Bax protein ratio in the cell J Clin Invest 101 1998 1326 1342
21. O.F. Bueno, L.J. De Windt, K.M. Tymitz, S.A. Witt, T.R. Kimball, and R. Klevitsky The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice EMBO J 19 2000 6341 6350
22. I.S. Harris, S. Zhang, I. Treskov, A. Kovacs, C. Weinheimer, and A.J. Muslin Raf-1 kinase is required for cardiac hypertrophy and cardiomyocyte survival in response to pressure overload Circulation 110 2004 718 723
23. Y. Fujio, T. Nguyen, D. Wencker, R.N. Kitsis, and K. Walsh Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart Circulation 101 2000 660 667
24. F.B. Mehrhof, F.U. Müller, M.W. Bergmann, P. Li, Y. Wang, and W. Schmitz In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein Circulation 104 2001 2088 2094
25. A.A. Sharfuddin, R.M. Sandoval, D.T. Berg, G.E. McDougal, S.B. Campos, and C.L. Phillips Soluble thrombomodulin protects ischemic kidneys J Am Soc Nephrol 20 2009 524 534
26. M. Wolfgang, J. Boehme, and W. Stremmel Comparison of three commercially available thrombomodulin ELISA kits J Immunol Methods 286 2004 231 240
27. G. Sakaguchi, K. Tambara, Y. Sakakibara, M. Ozeki, M. Yamamoto, and G. Premaratne Control-released hepatocyte growth factor prevents the progression of heart failure in stroke-prone spontaneously hypertensive rats Ann Thorac Surg 79 2005 1627 1634
28. I. Friehs, R. Barillas, N.V. Vasilyev, N. Roy, F.X. McGowan, and P.J. del Nido Vascular endothelial growth factor prevents apoptosis and preserves contractile function in hypertrophied infant heart Circulation 114 Suppl I 2006 I290 I295
29. R.L. Duerr, S. Huang, H.R. Miraliakbar, R. Clark, K.R. Chien, and J. Ross Jr. Insulin-like growth factor-1 enhances ventricular hypertrophy and function during the onset of experimental cardiac failure J Clin Invest 95 1995 619 627
30. D. Béchard, T. Gentina, M. Delehedde, A. Scherpereel, M. Lyon, and M. Aumercier Endocan is a novel chondroitin sulfate/dermatan sulfate proteoglycan that promotes hepatocyte growth factor/scatter factor mitogenic activity J Biol Chem 276 2001 48341 48349
31. J. Tapon-Bretaudire, D. Chabut, M. Zierer, S. Matou, D. Helley, and A. Bros A fucosylated chondroitin sulfate from echinoderm modulates in vitro fibroblast growth factor 2-dependent angiogenesis Mol Cancer Res 1 2002 96 102