-
1
-
-
70349302892
-
-
AIHW (Australian Institute of Health and Welfare) & AACR (Australasian Association of Cancer Registries) Cancer series no. 46. Cat. no. CAN 42. Canberra: AIHW
-
AIHW (Australian Institute of Health and Welfare) & AACR (Australasian Association of Cancer Registries) 2008. Cancer in Australia: an overview. 2008. Cancer series no. 46. Cat. no. CAN 42. Canberra: AIHW.
-
(2008)
2008 Cancer in Australia: An Overview
-
-
-
2
-
-
0037103424
-
Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
-
DOI 10.1056/NEJMoa020461
-
Demetri GD, von Mehren M, Blanke CD, Van den Abbeele AD, Eisenberg B, Roberts PJ, et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med. 2002;Aug 15;347(7):472-80. (Pubitemid 34879334)
-
(2002)
New England Journal of Medicine
, vol.347
, Issue.7
, pp. 472-480
-
-
Demetri, G.D.1
Von Mehren, M.2
Blanke, C.D.3
Van Den Abbeele, A.D.4
Eisenberg, B.5
Roberts, P.J.6
Heinrich, M.C.7
Tuveson, D.A.8
Singer, S.9
Janicek, M.10
Fletcher, J.A.11
Silverman, S.G.12
Silberman, S.L.13
Capdeville, R.14
Kiese, B.15
Peng, B.16
Dimitrijevic, S.17
Druker, B.J.18
Corless, C.19
Fletcher, C.D.M.20
Joensuu, H.21
more..
-
3
-
-
20844433223
-
Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: Randomised trial
-
Sep 25-Oct 1
-
Verweij J, Casali PG, Zalcberg J, LeCesne A, Reichardt P, Blay JY, et al. Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial. Lancet 2004; Sep 25-Oct 1;364(9440):1127-34.
-
(2004)
Lancet
, vol.364
, Issue.9440
, pp. 1127-1134
-
-
Verweij, J.1
Casali, P.G.2
Zalcberg, J.3
LeCesne, A.4
Reichardt, P.5
Blay, J.Y.6
-
4
-
-
39149127634
-
Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the kit receptor tyrosine kinase: S0033
-
DOI 10.1200/JCO.2007.13.4452
-
Blanke CD, Rankin C, Demetri GD, Ryan CW, von Mehren M, Benjamin RS, et al. Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the kit receptor tyrosine kinase: S0033. J Clin Oncol. 2008; Feb 1;26(4):626-32. (Pubitemid 351264358)
-
(2008)
Journal of Clinical Oncology
, vol.26
, Issue.4
, pp. 626-632
-
-
Blanke, C.D.1
Rankin, C.2
Demetri, G.D.3
Ryan, C.W.4
Von Mehren, M.5
Benjamin, R.S.6
Raymond, A.K.7
Bramwell, V.H.C.8
Baker, L.H.9
Maki, R.G.10
Tanaka, M.11
Hecht, J.R.12
Heinrich, M.C.13
Fletcher, C.D.M.14
Crowley, J.J.15
Borden, E.C.16
-
5
-
-
78649395548
-
Importance of molecular genetics of sarcomas
-
Thomas D. Importance of molecular genetics of sarcomas. Cancer Forum. 2010;34(3):154-156
-
(2010)
Cancer Forum
, vol.34
, Issue.3
, pp. 154-156
-
-
Thomas, D.1
-
6
-
-
18844475615
-
Randomised phase II trial of pegylated liposomal doxorubicin (DOXIL/CAELYX) versus doxorubicin in the treatment of advanced or metastatic soft tissue sarcoma: A study by the EORTC Soft Tissue and Bone Sarcoma Group
-
DOI 10.1016/S0959-8049(01)00050-8, PII S0959804901000508
-
Judson I, Radford JA, Harris M, Blay JY, van Hoesel Q, le Cesne A, et al. Randomised phase II trial of pegylated liposomal doxorubicin (DOXIL/CAELYX) versus doxorubicin in the treatment of advanced or metastatic soft tissue sarcoma: a study by the EORTC Soft Tissue and Bone Sarcoma Group. Eur J Cancer. 2001; May;37(7):870-7. (Pubitemid 32323965)
-
(2001)
European Journal of Cancer
, vol.37
, Issue.7
, pp. 870-877
-
-
Judson, I.1
Radford, J.A.2
Harris, M.3
Blay, J.-Y.4
Van Hoesel, Q.5
Le Cesne, A.6
Van Oosterom, A.T.7
Clemons, M.J.8
Kamby, C.9
Hermans, C.10
Whittaker, J.11
Donato Di Paola, E.12
Verweij, J.13
Nielsen, S.14
-
7
-
-
0023176119
-
Randomized comparison of three adriamycin regimens for metastatic soft tissue sarcomas
-
Borden EC, Amato DA, Rosenbaum C, Enterline HT, Shiraki MJ, Creech RH, et al. Randomized comparison of three adriamycin regimens for metastatic soft tissue sarcomas. J Clin Oncol. 1987; Jun;5(6):840-50. (Pubitemid 17119988)
-
(1987)
Journal of Clinical Oncology
, vol.5
, Issue.6
, pp. 840-850
-
-
Borden, E.C.1
Amato, D.A.2
Rosenbaum, C.3
-
8
-
-
0027256397
-
Randomized comparison of doxorubicin alone versus ifosfamide plus doxorubicin or mitomycin, doxorubicin, and cisplatin against advanced soft tissue sarcomas
-
Jul
-
Edmonson JH, Ryan LM, Blum RH, Brooks JS, Shiraki M, Frytak S, et al. Randomized comparison of doxorubicin alone versus ifosfamide plus doxorubicin or mitomycin, doxorubicin, and cisplatin against advanced soft tissue sarcomas. J Clin Oncol. 1993; Jul;11(7):1269-75.
-
(1993)
J Clin Oncol
, vol.11
, Issue.7
, pp. 1269-1275
-
-
Edmonson, J.H.1
Ryan, L.M.2
Blum, R.H.3
Brooks, J.S.4
Shiraki, M.5
Frytak, S.6
-
9
-
-
0029005580
-
Doxorubicin versus CYVADIC versus doxorubicin plus ifosfamide in first-line treatment of advanced soft tissue sarcomas: A randomized study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
-
Jul
-
Santoro A, Tursz T, Mouridsen H, Verweij J, Steward W, Somers R, et al. Doxorubicin versus CYVADIC versus doxorubicin plus ifosfamide in first-line treatment of advanced soft tissue sarcomas: a randomized study of the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group. J Clin Oncol. 1995; Jul;13(7):1537-45.
-
(1995)
J Clin Oncol.
, vol.13
, Issue.7
, pp. 1537-1545
-
-
Santoro, A.1
Tursz, T.2
Mouridsen, H.3
Verweij, J.4
Steward, W.5
Somers, R.6
-
10
-
-
0033566150
-
Ecteinascidin 743: A minor groove alkylator that bends DNA toward the major groove
-
DOI 10.1021/jm990241l
-
Zewail-Foote M, Hurley LH. Ecteinascidin 743: a minor groove alkylator that bends DNA toward the major groove. J Med Chem. 1999; Jul 15;42(14):2493-7. (Pubitemid 29344290)
-
(1999)
Journal of Medicinal Chemistry
, vol.42
, Issue.14
, pp. 2493-2497
-
-
Zewail-Foote, M.1
Hurley, L.H.2
-
11
-
-
17944374027
-
Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair
-
Aug
-
Takebayashi Y, Pourquier P, Zimonjic DB, Nakayama K, Emmert S, Ueda T, et al. Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair. Nat Med. 2001; Aug;7(8):961-6.
-
(2001)
Nat Med
, vol.7
, Issue.8
, pp. 961-966
-
-
Takebayashi, Y.1
Pourquier, P.2
Zimonjic, D.B.3
Nakayama, K.4
Emmert, S.5
Ueda, T.6
-
12
-
-
0035146702
-
Ecteinascidin-743 (ET-743), a natural marine compound, with a unique mechanism of action
-
PII S0959804900003579
-
Erba E, Bergamaschi D, Bassano L, Damia G, Ronzoni S, Faircloth GT, et al. Ecteinascidin-743 (ET-743), a natural marine compound, with a unique mechanism of action. Eur J Cancer. 2001; Jan;37(1):97-105. (Pubitemid 32119366)
-
(2001)
European Journal of Cancer
, vol.37
, Issue.1
, pp. 97-105
-
-
Erba, E.1
Bergamaschi, D.2
Bassano, L.3
Damia, G.4
Ronzoni, S.5
Faircloth, G.T.6
D'Incalci, M.7
-
13
-
-
0031766324
-
In vitro antitumor activity of the novel marine agent, ecteinascidin-743 (ET-743, NSC-648766) against human tumors explanted from patients
-
Sep
-
Izbicka E, Lawrence R, Raymond E, Eckhardt G, Faircloth G, Jimeno J, et al. In vitro antitumor activity of the novel marine agent, ecteinascidin-743 (ET-743, NSC-648766) against human tumors explanted from patients. Ann Oncol. 1998; Sep;9(9):981-7.
-
(1998)
Ann Oncol
, vol.9
, Issue.9
, pp. 981-987
-
-
Izbicka, E.1
Lawrence, R.2
Raymond, E.3
Eckhardt, G.4
Faircloth, G.5
Jimeno, J.6
-
14
-
-
0034813203
-
Sensitivity of soft tissue sarcoma cell lines to chemotherapeutic agents: Identification of ecteinascidin-743 as a potent cytotoxic agent
-
Sep
-
Li WW, Takahashi N, Jhanwar S, Cordon-Cardo C, Elisseyeff Y, Jimeno J, et al. Sensitivity of soft tissue sarcoma cell lines to chemotherapeutic agents: identification of ecteinascidin-743 as a potent cytotoxic agent. Clin Cancer Res. 2001; Sep;7(9):2908-11.
-
(2001)
Clin Cancer Res
, vol.7
, Issue.9
, pp. 2908-2911
-
-
Li, W.W.1
Takahashi, N.2
Jhanwar, S.3
Cordon-Cardo, C.4
Elisseyeff, Y.5
Jimeno, J.6
-
15
-
-
0032693607
-
High antitumour activity of ET743 against human tumour xenografts from melanoma, non-small-cell lung and ovarian cancer
-
Oct
-
Hendriks HR, Fiebig HH, Giavazzi R, Langdon SP, Jimeno JM, Faircloth GT. High antitumour activity of ET743 against human tumour xenografts from melanoma, non-small-cell lung and ovarian cancer. Ann Oncol. 1999; Oct;10(10):1233-40.
-
(1999)
Ann Oncol
, vol.10
, Issue.10
, pp. 1233-1240
-
-
Hendriks, H.R.1
Fiebig, H.H.2
Giavazzi, R.3
Langdon, S.P.4
Jimeno, J.M.5
Faircloth, G.T.6
-
16
-
-
0036239748
-
Clinical pharmacology of the novel marine-derived anticancer agent Ecteinascidin 743 administered as a 1- And 3-h infusion in a phase I study
-
Apr
-
van Kesteren C, Twelves C, Bowman A, Hoekman K, Lopez-Lazaro L, Jimeno J, et al. Clinical pharmacology of the novel marine-derived anticancer agent Ecteinascidin 743 administered as a 1- and 3-h infusion in a phase I study. Anticancer Drugs. 2002; Apr;13(4):381-93.
-
(2002)
Anticancer Drugs
, vol.13
, Issue.4
, pp. 381-393
-
-
Van Kesteren, C.1
Twelves, C.2
Bowman, A.3
Hoekman, K.4
Lopez-Lazaro, L.5
Jimeno, J.6
-
17
-
-
0035281641
-
Phase I and pharmacokinetic study of ecteinascidin-743, a new marine compound, administered as a 24-hour continuous infusion in patients with solid tumors
-
Mar 1
-
Taamma A, Misset JL, Riofrio M, Guzman C, Brain E, Lopez Lazaro L, et al. Phase I and pharmacokinetic study of ecteinascidin-743, a new marine compound, administered as a 24-hour continuous infusion in patients with solid tumors. J Clin Oncol. 2001; Mar 1;19(5):1256-65.
-
(2001)
J Clin Oncol
, vol.19
, Issue.5
, pp. 1256-1265
-
-
Taamma, A.1
Misset, J.L.2
Riofrio, M.3
Guzman, C.4
Brain, E.5
Lopez Lazaro, L.6
-
18
-
-
0036154945
-
A phase I and pharmacokinetic study of ecteinascidin-743 on a daily x 5 schedule in patients with solid malignancies
-
Jan
-
Villalona-Calero MA, Eckhardt SG, Weiss G, Hidalgo M, Beijnen JH, van Kesteren C, et al. A phase I and pharmacokinetic study of ecteinascidin-743 on a daily x 5 schedule in patients with solid malignancies. Clin Cancer Res. 2002; Jan;8(1):75-85.
-
(2002)
Clin Cancer Res
, vol.8
, Issue.1
, pp. 75-85
-
-
Villalona-Calero, M.A.1
Eckhardt, S.G.2
Weiss, G.3
Hidalgo, M.4
Beijnen, J.H.5
Van Kesteren, C.6
-
19
-
-
0035127175
-
Phase I and pharmacokinetic study of ecteinascidin 743 administered as a 72-hour continuous intravenous infusion in patients with solid malignancies
-
Feb
-
Ryan DP, Supko JG, Eder JP, Seiden MV, Demetri G, Lynch TJ, et al. Phase I and pharmacokinetic study of ecteinascidin 743 administered as a 72-hour continuous intravenous infusion in patients with solid malignancies. Clin Cancer Res. 2001; Feb;7(2):231-42.
-
(2001)
Clin Cancer Res
, vol.7
, Issue.2
, pp. 231-242
-
-
Ryan, D.P.1
Supko, J.G.2
Eder, J.P.3
Seiden, M.V.4
Demetri, G.5
Lynch, T.J.6
-
20
-
-
2342461682
-
Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy
-
Apr 15
-
Garcia-Carbonero R, Supko JG, Manola J, Seiden MV, Harmon D, Ryan DP, et al. Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy. J Clin Oncol. 2004; Apr 15;22(8):1480-90.
-
(2004)
J Clin Oncol
, vol.22
, Issue.8
, pp. 1480-1490
-
-
Garcia-Carbonero, R.1
Supko, J.G.2
Manola, J.3
Seiden, M.V.4
Harmon, D.5
Ryan, D.P.6
-
21
-
-
20044372153
-
Phase II study of ET-743 in advanced soft tissue sarcomas: A European Organisation for the Research and Treatment of Cancer (EORTC) soft tissue and bone sarcoma group trial
-
Jan 20
-
Le Cesne A, Blay JY, Judson I, Van Oosterom A, Verweij J, Radford J, et al. Phase II study of ET-743 in advanced soft tissue sarcomas: a European Organisation for the Research and Treatment of Cancer (EORTC) soft tissue and bone sarcoma group trial. J Clin Oncol. 2005; Jan 20;23(3):576-84.
-
(2005)
J Clin Oncol
, vol.23
, Issue.3
, pp. 576-584
-
-
Le Cesne, A.1
Blay, J.Y.2
Judson, I.3
Van Oosterom, A.4
Verweij, J.5
Radford, J.6
-
22
-
-
1542398698
-
Phase II study of ecteinascidin-743 in advanced pretreated soft tissue sarcoma patients
-
Mar 1
-
Yovine A, Riofrio M, Blay JY, Brain E, Alexandre J, Kahatt C, et al. Phase II study of ecteinascidin-743 in advanced pretreated soft tissue sarcoma patients. J Clin Oncol. 2004; Mar 1;22(5):890-9.
-
(2004)
J Clin Oncol
, vol.22
, Issue.5
, pp. 890-899
-
-
Yovine, A.1
Riofrio, M.2
Blay, J.Y.3
Brain, E.4
Alexandre, J.5
Kahatt, C.6
-
23
-
-
70249101414
-
Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: Results of a randomized phase II study of two different schedules
-
Sep 1
-
Demetri GD, Chawla SP, von Mehren M, Ritch P, Baker LH, Blay JY, et al. Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules. J Clin Oncol. 2009; Sep 1;27(25):4188-96.
-
(2009)
J Clin Oncol
, vol.27
, Issue.25
, pp. 4188-4196
-
-
Demetri, G.D.1
Chawla, S.P.2
Von Mehren, M.3
Ritch, P.4
Baker, L.H.5
Blay, J.Y.6
-
24
-
-
24944460785
-
Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: Multicenter phase II and pharmacokinetic study
-
Aug 20
-
Garcia-Carbonero R, Supko JG, Maki RG, Manola J, Ryan DP, Harmon D, et al. Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: multicenter phase II and pharmacokinetic study. J Clin Oncol. 2005; Aug 20;23(24):5484-92.
-
(2005)
J Clin Oncol
, vol.23
, Issue.24
, pp. 5484-5492
-
-
Garcia-Carbonero, R.1
Supko, J.G.2
Maki, R.G.3
Manola, J.4
Ryan, D.P.5
Harmon, D.6
-
25
-
-
0036189675
-
Progression-free rate as the principal end-point for phase II trials in soft-tissue sarcomas
-
Mar
-
Van Glabbeke M, Verweij J, Judson I, Nielsen OS. Progression-free rate as the principal end-point for phase II trials in soft-tissue sarcomas. Eur J Cancer. 2002; Mar;38(4):543-9.
-
(2002)
Eur J Cancer
, vol.38
, Issue.4
, pp. 543-549
-
-
Van Glabbeke, M.1
Verweij, J.2
Judson, I.3
Nielsen, O.S.4
-
26
-
-
34347214071
-
Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: A retrospective study
-
Jul
-
Grosso F, Jones RL, Demetri GD, Judson IR, Blay JY, Le Cesne A, et al. Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study. Lancet Oncol. 2007; Jul;8(7):595-602.
-
(2007)
Lancet Oncol
, vol.8
, Issue.7
, pp. 595-602
-
-
Grosso, F.1
Jones, R.L.2
Demetri, G.D.3
Judson, I.R.4
Blay, J.Y.5
Le Cesne, A.6
-
27
-
-
78649405108
-
Trabectedin (Tr) in the treatment of advanced uterine leiomyosarcomas (U-LMS). Results of a pooled analysis of five single-agent phase II studies using the recommended dose
-
May 20; abstr 10028
-
Judson IR, Blay J, Chawla SP, Radford JA, Le Cesne A, Verweij J, et al. Trabectedin (Tr) in the treatment of advanced uterine leiomyosarcomas (U-LMS). Results of a pooled analysis of five single-agent phase II studies using the recommended dose. J Clin Oncol. 2010; May 20;28, 15s (suppl; abstr 10028).
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL.
-
-
Judson, I.R.1
Blay, J.2
Chawla, S.P.3
Radford, J.A.4
Le Cesne, A.5
Verweij, J.6
-
28
-
-
34447572873
-
Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas: Results of sarcoma alliance for research through collaboration study 002
-
[corrected]. Jul 1
-
Maki RG, Wathen JK, Patel SR, Priebat DA, Okuno SH, Samuels B, et al. Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas: results of sarcoma alliance for research through collaboration study 002 [corrected]. J Clin Oncol. 2007; Jul 1;25(19):2755-63.
-
(2007)
J Clin Oncol
, vol.25
, Issue.19
, pp. 2755-2763
-
-
Maki, R.G.1
Wathen, J.K.2
Patel, S.R.3
Priebat, D.A.4
Okuno, S.H.5
Samuels, B.6
-
29
-
-
2442635522
-
Laboratory and clinical evidence of synergistic cytotoxicity of sequential treatment with gemcitabine followed by docetaxel in the treatment of sarcoma
-
May 1
-
Leu KM, Ostruszka LJ, Shewach D, Zalupski M, Sondak V, Biermann JS, et al. Laboratory and clinical evidence of synergistic cytotoxicity of sequential treatment with gemcitabine followed by docetaxel in the treatment of sarcoma. J Clin Oncol. 2004; May 1;22(9):1706-12.
-
(2004)
J Clin Oncol
, vol.22
, Issue.9
, pp. 1706-1712
-
-
Leu, K.M.1
Ostruszka, L.J.2
Shewach, D.3
Zalupski, M.4
Sondak, V.5
Biermann, J.S.6
-
30
-
-
33745444832
-
Docetaxel and gemcitabine combination in 133 advanced soft-tissue sarcomas: A retrospective analysis
-
Aug 1
-
Bay JO, Ray-Coquard I, Fayette J, Leyvraz S, Cherix S, Piperno-Neumann S, et al. Docetaxel and gemcitabine combination in 133 advanced soft-tissue sarcomas: a retrospective analysis. Int J Cancer. 2006; Aug 1;119(3):706-11.
-
(2006)
Int J Cancer
, vol.119
, Issue.3
, pp. 706-711
-
-
Bay, J.O.1
Ray-Coquard, I.2
Fayette, J.3
Leyvraz, S.4
Cherix, S.5
Piperno-Neumann, S.6
-
31
-
-
0037096747
-
Gemcitabine and docetaxel in patients with unresectable leiomyosarcoma: Results of a phase II trial
-
Jun 15
-
Hensley ML, Maki R, Venkatraman E, Geller G, Lovegren M, Aghajanian C, et al. Gemcitabine and docetaxel in patients with unresectable leiomyosarcoma: results of a phase II trial. J Clin Oncol. 2002; Jun 15;20(12):2824-31.
-
(2002)
J Clin Oncol
, vol.20
, Issue.12
, pp. 2824-2831
-
-
Hensley, M.L.1
Maki, R.2
Venkatraman, E.3
Geller, G.4
Lovegren, M.5
Aghajanian, C.6
-
32
-
-
0142121290
-
Randomized phase II comparison of dose-intense gemcitabine: Thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma
-
Sep 15
-
Tempero M, Plunkett W, Ruiz Van Haperen V, Hainsworth J, Hochster H, Lenzi R, et al. Randomized phase II comparison of dose-intense gemcitabine: thirty-minute infusion and fixed dose rate infusion in patients with pancreatic adenocarcinoma. J Clin Oncol. 2003; Sep 15;21(18):3402-8.
-
(2003)
J Clin Oncol
, vol.21
, Issue.18
, pp. 3402-3408
-
-
Tempero, M.1
Plunkett, W.2
Van Ruiz Haperen, V.3
Hainsworth, J.4
Hochster, H.5
Lenzi, R.6
-
33
-
-
0035424877
-
Phase II clinical investigation of gemcitabine in advanced soft tissue sarcomas and window evaluation of dose rate on gemcitabine triphosphate accumulation
-
Aug 1
-
Patel SR, Gandhi V, Jenkins J, Papadopolous N, Burgess MA, Plager C, et al. Phase II clinical investigation of gemcitabine in advanced soft tissue sarcomas and window evaluation of dose rate on gemcitabine triphosphate accumulation. J Clin Oncol. 2001; Aug 1;19(15):3483-9.
-
(2001)
J Clin Oncol
, vol.19
, Issue.15
, pp. 3483-3489
-
-
Patel, S.R.1
Gandhi, V.2
Jenkins, J.3
Papadopolous, N.4
Burgess, M.A.5
Plager, C.6
-
34
-
-
53149109402
-
Gemcitabine at fixed dose-rate in patients with advanced soft-tissue sarcomas: A mono-institutional phase II study
-
Dec
-
Ferraresi V, Ciccarese M, Cercato MC, Nuzzo C, Zeuli M, Di Filippo F, et al. Gemcitabine at fixed dose-rate in patients with advanced soft-tissue sarcomas: a mono-institutional phase II study. Cancer Chemother Pharmacol. 2008; Dec;63(1):149-55.
-
(2008)
Cancer Chemother Pharmacol
, vol.63
, Issue.1
, pp. 149-155
-
-
Ferraresi, V.1
Ciccarese, M.2
Cercato, M.C.3
Nuzzo, C.4
Zeuli, M.5
Di Filippo, F.6
-
35
-
-
0344839034
-
Phase II trial of gemcitabine in patients wrth advanced sarcomas (E1797). A trial of the Eastern Cooperative Oncology Group
-
Apr 15
-
Okuno S, Ryan LM, Edmonson JH, Priebat DA, Blum RH. Phase II trial of gemcitabine in patients wrth advanced sarcomas (E1797). a trial of the Eastern Cooperative Oncology Group Cancer. 2003; Apr 15;97(8):1969-73.
-
(2003)
Cancer
, vol.97
, Issue.8
, pp. 1969-1973
-
-
Okuno, S.1
Ryan, L.M.2
Edmonson, J.H.3
Priebat, D.A.4
Blum, R.H.5
-
36
-
-
33644869706
-
Phase II trial of gemcitabine as first line chemotherapy in patients with metastatic or unresectable soft tissue sarcoma
-
Feb
-
Von Burton G, Rankin C, Zalupski MM, Mills GM, Borden EC, Karen A Phase II trial of gemcitabine as first line chemotherapy in patients with metastatic or unresectable soft tissue sarcoma. Am J Clin Oncol. 2006; Feb;29(1):59-61.
-
(2006)
Am J Clin Oncol
, vol.29
, Issue.1
, pp. 59-61
-
-
Von Burton, G.1
Rankin, C.2
Zalupski, M.M.3
Mills, G.M.4
Borden, E.C.5
Karen, A.6
-
37
-
-
33646567780
-
An open label, non-comparative phase II study of gemcitabine as salvage treatment for patients with pretreated adult type soft tissue sarcoma
-
May
-
Hartmann JT, Oechsle K, Huober J, Jakob A, Azemar M, Horger M, et al. An open label, non-comparative phase II study of gemcitabine as salvage treatment for patients with pretreated adult type soft tissue sarcoma. Invest New Drugs. 2006; May;24(3):249-53.
-
(2006)
Invest New Drugs
, vol.24
, Issue.3
, pp. 249-253
-
-
Hartmann, J.T.1
Oechsle, K.2
Huober, J.3
Jakob, A.4
Azemar, M.5
Horger, M.6
-
38
-
-
0033952086
-
Gemcitabine in soft tissue or bone sarcoma resistant to standard chemotherapy: A phase II study
-
Merimsky O, Meller I, Flusser G, Kollender Y, Issakov J, Weil-Ben-Arush M, et al. Gemcitabine in soft tissue or bone sarcoma resistant to standard chemotherapy: a phase II study. Cancer Chemother Pharmacol. 2000;45(2):177-81.
-
(2000)
Cancer Chemother Pharmacol
, vol.45
, Issue.2
, pp. 177-181
-
-
Merimsky, O.1
Meller, I.2
Flusser, G.3
Kollender, Y.4
Issakov, J.5
Weil-Ben-Arush, M.6
-
39
-
-
0036192160
-
Gemcitabine in advanced adult soft-tissue sarcomas. A phase II study of the EORTC Soft Tissue and Bone Sarcoma Group
-
Mar
-
Svancarova L, Blay JY, Judson IR, van Hoesel QG, van Oosterom AT, le Cesne A, et al. Gemcitabine in advanced adult soft-tissue sarcomas. A phase II study of the EORTC Soft Tissue and Bone Sarcoma Group. Eur J Cancer. 2002; Mar;38(4):556-9.
-
(2002)
Eur J Cancer
, vol.38
, Issue.4
, pp. 556-559
-
-
Svancarova, L.1
Blay, J.Y.2
Judson, I.R.3
Van Hoesel, Q.G.4
Van Oosterom, A.T.5
Le Cesne, A.6
-
40
-
-
0028335697
-
Phase II study with docetaxel (Taxotere) in advanced soft tissue sarcomas of the adult
-
EORTC Soft Tissue and Bone Sarcoma Group Jul
-
van Hoesel QG, Verweij J, Catimel G, Clavel M, Kerbrat P, van Oosterom AT, et al. Phase II study with docetaxel (Taxotere) in advanced soft tissue sarcomas of the adult. EORTC Soft Tissue and Bone Sarcoma Group. Ann Oncol. 1994; Jul;5(6):539-42.
-
(1994)
Ann Oncol
, vol.5
, Issue.6
, pp. 539-542
-
-
Van Hoesel, Q.G.1
Verweij, J.2
Catimel, G.3
Clavel, M.4
Kerbrat, P.5
Van Oosterom, A.T.6
-
41
-
-
18144448739
-
Randomized phase II study of docetaxel versus doxorubicin in first- And second-line chemotherapy for locally advanced or metastatic soft tissue sarcomas in adults: A study of the european organization for research and treatment of cancer soft tissue and bone sarcoma group
-
May
-
Verweij J, Lee SM, Ruka W, Buesa J, Coleman R, van Hoessel R, et al. Randomized phase II study of docetaxel versus doxorubicin in first- and second-line chemotherapy for locally advanced or metastatic soft tissue sarcomas in adults: a study of the european organization for research and treatment of cancer soft tissue and bone sarcoma group. J Clin Oncol. 2000; May;18(10):2081-6.
-
(2000)
J Clin Oncol
, vol.18
, Issue.10
, pp. 2081-2086
-
-
Verweij, J.1
Lee, S.M.2
Ruka, W.3
Buesa, J.4
Coleman, R.5
Van Hoessel, R.6
-
42
-
-
0037314665
-
In vitro schedule-dependent interaction between docetaxel and gemcitabine in human gastric cancer cell lines
-
Feb
-
Ricotti L, Tesei A, De Paola F, Ulivi P, Frassineti GL, Milandri C, et al. In vitro schedule-dependent interaction between docetaxel and gemcitabine in human gastric cancer cell lines. Clin Cancer Res. 2003; Feb;9(2):900-5.
-
(2003)
Clin Cancer Res
, vol.9
, Issue.2
, pp. 900-905
-
-
Ricotti, L.1
Tesei, A.2
De Paola, F.3
Ulivi, P.4
Frassineti, G.L.5
Milandri, C.6
-
43
-
-
0031915353
-
Interaction of gemcitabine with paclitaxel and cisplatin in human tumor cell lines
-
Apr
-
Theodossiou C, Cook JA, Fisher J, Teague D, Liebmann JE, Russo A, et al. Interaction of gemcitabine with paclitaxel and cisplatin in human tumor cell lines. Int J Oncol. 1998; Apr;12(4):825-32.
-
(1998)
Int J Oncol
, vol.12
, Issue.4
, pp. 825-832
-
-
Theodossiou, C.1
Cook, J.A.2
Fisher, J.3
Teague, D.4
Liebmann, J.E.5
Russo, A.6
-
44
-
-
0033778922
-
Sequence dependent effect of paclitaxel on gemcitabine metabolism in relation to cell cycle and cytotoxicity in non-small-cell lung cancer cell lines
-
Oct
-
Kroep JR, Giaccone G, Tolis C, Voorn DA, Loves WJ, Groeningen CJ, et al. Sequence dependent effect of paclitaxel on gemcitabine metabolism in relation to cell cycle and cytotoxicity in non-small-cell lung cancer cell lines. Br J Cancer. 2000; Oct;83(8):1069-76.
-
(2000)
Br J Cancer
, vol.83
, Issue.8
, pp. 1069-1076
-
-
Kroep, J.R.1
Giaccone, G.2
Tolis, C.3
Voorn, D.A.4
Loves, W.J.5
Groeningen, C.J.6
-
45
-
-
33644858419
-
Giant cell tumor of bone
-
Feb
-
Mendenhall WM, Zlotecki RA, Scarborough MT, Gibbs CP, Mendenhall NP. Giant cell tumor of bone. Am J Clin Oncol. 2006; Feb;29(1):96-9.
-
(2006)
Am J Clin Oncol
, vol.29
, Issue.1
, pp. 96-99
-
-
Mendenhall, W.M.1
Zlotecki, R.A.2
Scarborough, M.T.3
Gibbs, C.P.4
Mendenhall, N.P.5
-
46
-
-
0034078583
-
Expression of osteoclast differentiation signals by stromal elements of giant cell tumors
-
Apr
-
Atkins GJ, Haynes DR, Graves SE, Evdokiou A, Hay S, Bouralexis S, et al. Expression of osteoclast differentiation signals by stromal elements of giant cell tumors. J Bone Miner Res. 2000; Apr;15(4):640-9.
-
(2000)
J Bone Miner Res
, vol.15
, Issue.4
, pp. 640-649
-
-
Atkins, G.J.1
Haynes, D.R.2
Graves, S.E.3
Evdokiou, A.4
Hay, S.5
Bouralexis, S.6
-
47
-
-
0033873632
-
Gene expression of osteoprotegerin ligand, osteoprotegerin, and receptor activator of NF-kappaB in giant cell tumor of bone: Possible involvement in tumor cell-induced osteoclast-like cell formation
-
Mar
-
Huang L, Xu J, Wood DJ, Zheng MH. Gene expression of osteoprotegerin ligand, osteoprotegerin, and receptor activator of NF-kappaB in giant cell tumor of bone: possible involvement in tumor cell-induced osteoclast-like cell formation. Am J Pathol. 2000; Mar;156(3):761-7.
-
(2000)
Am J Pathol
, vol.156
, Issue.3
, pp. 761-767
-
-
Huang, L.1
Xu, J.2
Wood, D.J.3
Zheng, M.H.4
-
48
-
-
0036329036
-
RANK (receptor activator of nuclear factor kappa B) and RANK ligand are expressed in giant cell tumors of bone
-
Feb
-
Roux S, Amazit L, Meduri G, Guiochon-Mantel A, Milgrom E, Mariette X RANK (receptor activator of nuclear factor kappa B) and RANK ligand are expressed in giant cell tumors of bone. Am J Clin Pathol. 2002; Feb;117(2):210-6.
-
(2002)
Am J Clin Pathol
, vol.117
, Issue.2
, pp. 210-216
-
-
Roux, S.1
Amazit, L.2
Meduri, G.3
Guiochon-Mantel, A.4
Milgrom, E.5
Mariette, X.6
-
49
-
-
24344444472
-
Phenotypic and molecular studies of giant-cell tumors of bone and soft tissue
-
Sep
-
Lau YS, Sabokbar A, Gibbons CL, Giele H, Athanasou N. Phenotypic and molecular studies of giant-cell tumors of bone and soft tissue. Hum Pathol. 2005; Sep;36(9):945-54.
-
(2005)
Hum Pathol
, vol.36
, Issue.9
, pp. 945-954
-
-
Lau, Y.S.1
Sabokbar, A.2
Gibbons, C.L.3
Giele, H.4
Athanasou, N.5
-
50
-
-
77349120482
-
Denosumab in patients with giant-cell tumour of bone: An open-label, phase 2 study
-
Mar
-
Thomas D, Henshaw R, Skubitz K, Chawla S, Staddon A, Blay JY, et al. Denosumab in patients with giant-cell tumour of bone: an open-label, phase 2 study. Lancet Oncol. 2010; Mar;11(3):275-80.
-
(2010)
Lancet Oncol
, vol.11
, Issue.3
, pp. 275-280
-
-
Thomas, D.1
Henshaw, R.2
Skubitz, K.3
Chawla, S.4
Staddon, A.5
Blay, J.Y.6
-
51
-
-
2342559981
-
The TOR pathway: A target for cancer therapy
-
May
-
Bjornsti MA, Houghton PJ. The TOR pathway: a target for cancer therapy. Nat Rev Cancer. 2004; May;4(5):335-48.
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.5
, pp. 335-348
-
-
Bjornsti, M.A.1
Houghton, P.J.2
-
52
-
-
0028360374
-
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
-
Jun 30
-
Brown EJ, Albers MW, Shin TB, Ichikawa K, Keith CT, Lane WS, et al. A mammalian protein targeted by G1-arresting rapamycin-receptor complex. Nature. 1994; Jun 30;369(6483):756-8.
-
(1994)
Nature
, vol.369
, Issue.6483
, pp. 756-758
-
-
Brown, E.J.1
Albers, M.W.2
Shin, T.B.3
Ichikawa, K.4
Keith, C.T.5
Lane, W.S.6
-
53
-
-
0034644525
-
TOR, a central controller of cell growth
-
Oct 13
-
Schmelzle T, Hall MN TOR, a central controller of cell growth. Cell 2000; Oct 13;103(2):253-62.
-
(2000)
Cell
, vol.103
, Issue.2
, pp. 253-262
-
-
Schmelzle, T.1
Hall, M.N.2
-
54
-
-
33745307617
-
Ras, PI(3)K and mTOR signalling controls tumour cell growth
-
May 25
-
Shaw RJ, Cantley LC. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature. 2006; May 25;441(7092):424-30.
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 424-430
-
-
Shaw, R.J.1
Cantley, L.C.2
-
55
-
-
7944223834
-
Targeting the mammalian target of rapamycin (mTOR): A new approach to treating cancer
-
Oct 18
-
Chan S. Targeting the mammalian target of rapamycin (mTOR): a new approach to treating cancer. Br J Cancer. 2004; Oct 18;91(8):1420-4.
-
(2004)
Br J Cancer
, vol.91
, Issue.8
, pp. 1420-1424
-
-
Chan, S.1
-
56
-
-
32044466838
-
Exploiting the PI3K/AKT pathway for cancer drug discovery
-
Dec
-
Hennessy BT, Smith DL, Ram PT, Lu Y, Mills GB. Exploiting the PI3K/AKT pathway for cancer drug discovery. Nat Rev Drug Discov. 2005; Dec;4(12):988-1004.
-
(2005)
Nat Rev Drug Discov
, vol.4
, Issue.12
, pp. 988-1004
-
-
Hennessy, B.T.1
Smith, D.L.2
Ram, P.T.3
Lu, Y.4
Mills, G.B.5
-
57
-
-
38649140450
-
Phase I trial of the novel mammalian target of rapamycin inhibitor deforolimus (AP23573, MK-8669) administered intravenously daily for 5 days every 2 weeks to patients with advanced malignancies
-
Jan 20
-
Mita MM, Mita AC, Chu QS, Rowinsky EK, Fetterly GJ, Goldston M, et al. Phase I trial of the novel mammalian target of rapamycin inhibitor deforolimus (AP23573, MK-8669) administered intravenously daily for 5 days every 2 weeks to patients with advanced malignancies. J Clin Oncol. 2008; Jan 20;26(3):361-7.
-
(2008)
J Clin Oncol
, vol.26
, Issue.3
, pp. 361-367
-
-
Mita, M.M.1
Mita, A.C.2
Chu, Q.S.3
Rowinsky, E.K.4
Fetterly, G.J.5
Goldston, M.6
-
58
-
-
37149033966
-
Survival results with AP23573, a novel mTOR inhibitor, in patients (pts) with advanced soft tissue or bone sarcomas: Update of phase II trial
-
Jun 20; abstr 10076
-
Chawla SP, Staddon AP, Schuetze SM, D'Amato GZ, Blay JY, Sankhala KK, et al. Survival results with AP23573, a novel mTOR inhibitor, in patients (pts) with advanced soft tissue or bone sarcomas: Update of phase II trial. J Clin Oncol. 2007; Jun 20;2418s (suppl. abstr 10076).
-
(2007)
J Clin Oncol
, vol.24
, Issue.SUPPL.
-
-
Chawla, S.P.1
Staddon, A.P.2
Schuetze, S.M.3
D'Amato, G.Z.4
Blay, J.Y.5
Sankhala, K.K.6
-
59
-
-
33750238350
-
Updated results of a phase II trial of AP23573, a novel mTOR inhibitor, in patients (pts) with advanced soft tissue or bone sarcomas
-
Jun 20; abstr 9505
-
Chawla SP, Staddon AP, Schuetze SM, D'Amato GZ, Blay JY, Sankhala KK, et al. Updated results of a phase II trial of AP23573, a novel mTOR inhibitor, in patients (pts) with advanced soft tissue or bone sarcomas. J Clin Oncol. 2006; Jun 20;24:18s (suppl: abstr 9505).
-
(2006)
J Clin Oncol
, vol.24
, Issue.SUPPL.
-
-
Chawla, S.P.1
Staddon, A.P.2
Schuetze, S.M.3
D'Amato, G.Z.4
Blay, J.Y.5
Sankhala, K.K.6
-
60
-
-
33746840153
-
IGF-I mediated survival pathways in normal and malignant cells
-
Aug
-
Kurmasheva RT, Houghton PJ. IGF-I mediated survival pathways in normal and malignant cells. Biochim Biophys Acta. 2006; Aug;1766(1):1-22.
-
(2006)
Biochim Biophys Acta
, vol.1766
, Issue.1
, pp. 1-22
-
-
Kurmasheva, R.T.1
Houghton, P.J.2
-
61
-
-
54349093798
-
Insulin, insulin-like growth factors and neoplasia
-
Aug
-
Pollak M. Insulin, insulin-like growth factors and neoplasia. Best Pract Res Clin Endocrinol Metab. 2008; Aug;22(4):625-38.
-
(2008)
Best Pract Res Clin Endocrinol Metab
, vol.22
, Issue.4
, pp. 625-638
-
-
Pollak, M.1
-
62
-
-
33846874575
-
The role of the IGF system in cancer growth and metastasis: Overview and recent insights
-
Feb
-
Samani AA, Yakar S, LeRoith D, Brodt P. The role of the IGF system in cancer growth and metastasis: overview and recent insights. Endocr Rev 2007; Feb;28(1):20-47.
-
(2007)
Endocr Rev
, vol.28
, Issue.1
, pp. 20-47
-
-
Samani, A.A.1
Yakar, S.2
LeRoith, D.3
Brodt, P.4
-
63
-
-
17744417798
-
Blockage of insulin-like growth factor-I receptor inhibits the growth of Ewing's sarcoma in athymic mice
-
Sep 15
-
Scotlandi K, Benini S, Nanni P, Lollini PL, Nicoletti G, Landuzzi L, et al. Blockage of insulin-like growth factor-I receptor inhibits the growth of Ewing's sarcoma in athymic mice. Cancer Res. 1998; Sep 15;58(18):4127-31.
-
(1998)
Cancer Res
, vol.58
, Issue.18
, pp. 4127-4131
-
-
Scotlandi, K.1
Benini, S.2
Nanni, P.3
Lollini, P.L.4
Nicoletti, G.5
Landuzzi, L.6
-
64
-
-
0031785253
-
Inhibition of tumor growth by a dominant negative mutant of the insulin-like growth factor I receptor with a bystander effect
-
Nov
-
Reiss K, D'Ambrosio C, Tu X, Tu C, Baserga R. Inhibition of tumor growth by a dominant negative mutant of the insulin-like growth factor I receptor with a bystander effect. Clin Cancer Res. 1998; Nov;4(11):2647-55.
-
(1998)
Clin Cancer Res
, vol.4
, Issue.11
, pp. 2647-2655
-
-
Reiss, K.1
D'Ambrosio, C.2
Tu, X.3
Tu, C.4
Baserga, R.5
-
65
-
-
20144386856
-
Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871
-
Mar 1
-
Cohen BD, Baker DA, Soderstrom C, Tkalcevic G, Rossi AM, Miller PE, et al. Combination therapy enhances the inhibition of tumor growth with the fully human anti-type 1 insulin-like growth factor receptor monoclonal antibody CP-751,871. Clin Cancer Res. 2005; Mar 1;11(5):2063-73.
-
(2005)
Clin Cancer Res
, vol.11
, Issue.5
, pp. 2063-2073
-
-
Cohen, B.D.1
Baker, D.A.2
Soderstrom, C.3
Tkalcevic, G.4
Rossi, A.M.5
Miller, P.E.6
-
66
-
-
62849105383
-
The insulin-like growth factor system and sarcomas
-
Mar
-
Rikhof B, de Jong S, Suurmeijer AJ, Meijer C, van der Graaf WT. The insulin-like growth factor system and sarcomas. J Pathol. 2009; Mar;217(4):469-82.
-
(2009)
J Pathol
, vol.217
, Issue.4
, pp. 469-482
-
-
Rikhof, B.1
De Jong, S.2
Suurmeijer, A.J.3
Meijer, C.4
Van Der Graaf, W.T.5
-
67
-
-
78650750911
-
AMG 479 in relapsed or refractory Ewing's family tumours (EFT) or desmoplastic small round cell tumours (DSRCT). Phase II results
-
May 20; abstr 10001
-
Tap WD, Demetri GD, Barnette P, Desai J, Kavan P, Tozer R, et al. AMG 479 in relapsed or refractory Ewing's family tumours (EFT) or desmoplastic small round cell tumours (DSRCT). Phase II results. J Clin Oncol. 2010; May 20;28 15s (suppl; abstr 10001).
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL.
-
-
Tap, W.D.1
Demetri, G.D.2
Barnette, P.3
Desai, J.4
Kavan, P.5
Tozer, R.6
-
68
-
-
78649438066
-
Activity of R1507, a monoclonal antibody to the insulin-like growth factor-1 receptor (IGF1R), in patients (pts) with recurrent or refractory Ewing's sarcoma family of tumours (ESFT): Results of a Phase II SARC study
-
May 20; abstr 10000
-
Pappo AS, Patel S, Crowley J, Reinke DK, Staddon AP, Kuenkele K, et al. Activity of R1507, a monoclonal antibody to the insulin-like growth factor-1 receptor (IGF1R), in patients (pts) with recurrent or refractory Ewing's sarcoma family of tumours (ESFT): Results of a Phase II SARC study. J Clin Oncol. 2010, May 20;28: 15s (suppl; abstr 10000).
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL.
-
-
Pappo, A.S.1
Patel, S.2
Crowley, J.3
Reinke, D.K.4
Staddon, A.P.5
Kuenkele, K.6
-
69
-
-
75249097799
-
Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: A phase 1 expansion cohort study
-
Feb
-
Olmos D, Postel-Vinay S, Molife LR, Okuno SH, Schuetze SM, Paccagnella ML, et al. Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort study. Lancet Oncol. 2010; Feb;11(2):129-35.
-
(2010)
Lancet Oncol
, vol.11
, Issue.2
, pp. 129-135
-
-
Olmos, D.1
Postel-Vinay, S.2
Molife, L.R.3
Okuno, S.H.4
Schuetze, S.M.5
Paccagnella, M.L.6
-
70
-
-
33745212417
-
Insulin-like growth factor I receptor pathway inhibition by ADW742, alone or in combination with imatinib, doxorubicin, or vincristine, is a novel therapeutic approach in Ewing tumor
-
Jun 1
-
Martins AS, Mackintosh C, Martin DH, Campos M, Hernandez T, Ordonez JL, et al. Insulin-like growth factor I receptor pathway inhibition by ADW742, alone or in combination with imatinib, doxorubicin, or vincristine, is a novel therapeutic approach in Ewing tumor. Clin Cancer Res. 2006; Jun 1;12(11 Pt 1):3532-40.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.11 PART 1
, pp. 3532-3540
-
-
Martins, A.S.1
Mackintosh, C.2
Martin, D.H.3
Campos, M.4
Hernandez, T.5
Ordonez, J.L.6
-
71
-
-
20244364227
-
Inhibition of insulin-like growth factor I receptor increases the antitumor activity of doxorubicin and vincristine against Ewing's sarcoma cells
-
Jun
-
Benini S, Manara MC, Baldini N, Censano V, Massimo S, Mercuri M, et al. Inhibition of insulin-like growth factor I receptor increases the antitumor activity of doxorubicin and vincristine against Ewing's sarcoma cells. Clin Cancer Res. 2001; Jun;7(6):1790-7.
-
(2001)
Clin Cancer Res
, vol.7
, Issue.6
, pp. 1790-1797
-
-
Benini, S.1
Manara, M.C.2
Baldini, N.3
Censano, V.4
Massimo, S.5
Mercuri, M.6
-
72
-
-
78650992941
-
Alveolar Soft Part Sarcoma. Clinical Presentation, Treatment, and Outcome in a Series of 33 Patients at a Single Institution
-
Jul 1 [Epub ahead of print]
-
Pennacchioli E, Fiore M, Collini P, Radaelli S, Dileo P, Stacchiotti S, et al. Alveolar Soft Part Sarcoma. Clinical Presentation, Treatment, and Outcome in a Series of 33 Patients at a Single Institution. Ann Surg Oncol. 2010; Jul 1 [Epub ahead of print].
-
(2010)
Ann Surg Oncol
-
-
Pennacchioli, E.1
Fiore, M.2
Collini, P.3
Radaelli, S.4
Dileo, P.5
Stacchiotti, S.6
-
73
-
-
0035253488
-
Alveolar soft part sarcoma clinical course and patterns of metastasis in 70 patients treated at a single institution
-
Feb 1
-
Portera CA, Jr., Ho V, Patel SR, Hunt KK, Feig BW, Respondek PM, et al. Alveolar soft part sarcoma clinical course and patterns of metastasis in 70 patients treated at a single institution. Cancer 2001; Feb 1;91(3):585-91.
-
(2001)
Cancer
, vol.91
, Issue.3
, pp. 585-591
-
-
Portera Jr., C.A.1
Ho, V.2
Patel, S.R.3
Hunt, K.K.4
Feig, B.W.5
Respondek, P.M.6
-
74
-
-
0038307762
-
Chemotherapy in alveolar soft part sarcomas. What do we know?
-
Jul
-
Reichardt P, Lindner T, Pink D, Thuss-Patience PC, Kretzschmar A, Dorken B. Chemotherapy in alveolar soft part sarcomas. What do we know? Eur J Cancer. 2003; Jul;39(11):1511-6.
-
(2003)
Eur J Cancer
, vol.39
, Issue.11
, pp. 1511-1516
-
-
Reichardt, P.1
Lindner, T.2
Pink, D.3
Thuss-Patience, P.C.4
Kretzschmar, A.5
Dorken, B.6
-
75
-
-
0035804224
-
The der(17)t(X;17)(p11,q25) of human alveolar soft part sarcoma fuses the TFE3 transcription factor gene to ASPL, a novel gene at 17q25
-
Jan 4
-
Ladanyi M, Lui MY, Antonescu CR, Krause-Boehm A, Meindl A, Argani P, et al. The der(17)t(X;17)(p11,q25) of human alveolar soft part sarcoma fuses the TFE3 transcription factor gene to ASPL, a novel gene at 17q25. Oncogene. 2001; Jan 4;20(1):48-57.
-
(2001)
Oncogene
, vol.20
, Issue.1
, pp. 48-57
-
-
Ladanyi, M.1
Lui, M.Y.2
Antonescu, C.R.3
Krause-Boehm, A.4
Meindl, A.5
Argani, P.6
-
76
-
-
37549023043
-
Angiogenesis-promoting gene patterns in alveolar soft part sarcoma
-
Dec 15
-
Lazar AJ, Das P, Tuvin D, Korchin B, Zhu Q, Jin Z, et al. Angiogenesis-promoting gene patterns in alveolar soft part sarcoma. Clin Cancer Res. 2007; Dec 15;13(24):7314-21.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.24
, pp. 7314-7321
-
-
Lazar, A.J.1
Das, P.2
Tuvin, D.3
Korchin, B.4
Zhu, Q.5
Jin, Z.6
-
77
-
-
33847066415
-
TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition
-
Feb 1
-
Tsuda M, Davis IJ, Argani P, Shukla N, McGill GG, Nagai M, Saito T, Lae M, Fisher DE, Ladanyi M. TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition. Cancer Res. 2007; Feb 1;67(3):919-29.
-
(2007)
Cancer Res
, vol.67
, Issue.3
, pp. 919-929
-
-
Tsuda, M.1
Davis, I.J.2
Argani, P.3
Shukla, N.4
McGill, G.G.5
Nagai, M.6
Saito, T.7
Lae, M.8
Fisher, D.E.9
Ladanyi, M.10
-
78
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
-
Jan
-
Mendel DB, Laird AD, Xin X, Louie SG, Christensen JG, Li G, et al. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res. 2003; Jan;9(1):327-37.
-
(2003)
Clin Cancer Res
, vol.9
, Issue.1
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
Louie, S.G.4
Christensen, J.G.5
Li, G.6
-
79
-
-
0038204144
-
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
-
May 1
-
O'Farrell AM, Abrams TJ, Yuen HA, Ngai TJ, Louie SG, Yee KW, et al. SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo. Blood 2003; May 1;101(9):3597-605.
-
(2003)
Blood
, vol.101
, Issue.9
, pp. 3597-3605
-
-
O'Farrell, A.M.1
Abrams, T.J.2
Yuen, H.A.3
Ngai, T.J.4
Louie, S.G.5
Yee, K.W.6
-
80
-
-
78649396910
-
Sunitinib malate (SM) in alveolar soft part sarcoma (ASPS)
-
May 20; abstr 10014
-
Palassini E, Stacchiotti S, Negri T, Brich S, Marrari A, Morosi C, et al. Sunitinib malate (SM) in alveolar soft part sarcoma (ASPS). J Clin Oncol. 2010; May 20;28: 7s (suppl; abstr 10014).
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL.
-
-
Palassini, E.1
Stacchiotti, S.2
Negri, T.3
Brich, S.4
Marrari, A.5
Morosi, C.6
-
81
-
-
76749118404
-
Activity of cediranib, a highly potent and selective VEGF signaling inhibitor, in alveolar soft part sarcoma
-
May 20; suppl abstr 10523
-
Gardner K, Judson I, Leahy M, Barquin E, Marotti M, Collins B, et al. Activity of cediranib, a highly potent and selective VEGF signaling inhibitor, in alveolar soft part sarcoma. J Clin Oncol. 2009; May 20;27: 15s (suppl; abstr 10523).
-
(2009)
J Clin Oncol
, vol.27
-
-
Gardner, K.1
Judson, I.2
Leahy, M.3
Barquin, E.4
Marotti, M.5
Collins, B.6
-
82
-
-
76749121298
-
Preliminary results from a Phase II study of ARQ 197 in patients with microphthalmia transcription factor family (MiT)-associated tumors
-
May 20; suppl abstr 10502
-
Goldberg J, Demetri GD, Choy E, Rosen L, Pappo A, Dubois S, et al. Preliminary results from a Phase II study of ARQ 197 in patients with microphthalmia transcription factor family (MiT)-associated tumors. J Clin Oncol. 2009; May 20;27: 15s (suppl; abstr 10502).
-
(2009)
J Clin Oncol
, vol.27
-
-
Goldberg, J.1
Demetri, G.D.2
Choy, E.3
Rosen, L.4
Pappo, A.5
Dubois, S.6
-
83
-
-
67650337802
-
Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: A phase II study from the European organisation for research and treatment of cancer-soft tissue and bone sarcoma group (EORTC study 62043)
-
Jul 1
-
Sleijfer S, Ray-Coquard I, Papai Z, Le Cesne A, Scurr M, Schoffski P, et al. Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: a phase II study from the European organisation for research and treatment of cancer-soft tissue and bone sarcoma group (EORTC study 62043). J Clin Oncol 2009; Jul 1;27(19):3126-32.
-
(2009)
J Clin Oncol
, vol.27
, Issue.19
, pp. 3126-3132
-
-
Sleijfer, S.1
Ray-Coquard, I.2
Papai, Z.3
Le Cesne, A.4
Scurr, M.5
Schoffski, P.6
|