메뉴 건너뛰기




Volumn 30, Issue 6, 2010, Pages 702-705

Combined HTR2C-LEP genotype as a determinant of obesity in patients using antipsychotic medication

Author keywords

antipsychotic; leptin; obesity; pharmacogenetic

Indexed keywords

ANTIDIABETIC AGENT; ANTILIPEMIC AGENT; CLOZAPINE; LEPTIN; NEUROLEPTIC AGENT; OLANZAPINE; QUETIAPINE; RISPERIDONE; SEROTONIN 2 RECEPTOR;

EID: 78649341319     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/JCP.0b013e3181fa05a2     Document Type: Article
Times cited : (19)

References (26)
  • 1
    • 0032751075 scopus 로고    scopus 로고
    • Antipsychotic-induced weight gain: A comprehensive research synthesis
    • Allison DB, Mentore JL, Heo M, et al. Antipsychotic-induced weight gain: a comprehensive research synthesis. Am J Psychiatry. 1999;156: 1686-1696.
    • (1999) Am J Psychiatry. , vol.156 , pp. 1686-1696
    • Allison, D.B.1    Mentore, J.L.2    Heo, M.3
  • 2
    • 0035030227 scopus 로고    scopus 로고
    • Prevalence and extent of distress of adverse effects of antipsychotics among callers to a United Kingdom National Mental Health Helpline
    • Fakhoury WK, Wright D, Wallace M. Prevalence and extent of distress of adverse effects of antipsychotics among callers to a United Kingdom National Mental Health Helpline. Int Clin Psychopharmacol. 2001; 16:153-162.
    • (2001) Int Clin Psychopharmacol. , vol.16 , pp. 153-162
    • Fakhoury, W.K.1    Wright, D.2    Wallace, M.3
  • 3
    • 0035871492 scopus 로고    scopus 로고
    • Estimating the consequences of anti-psychotic induced weight gain on health and mortality rate
    • Fontaine KR, Heo M, Harrigan EP, et al. Estimating the consequences of anti-psychotic induced weight gain on health and mortality rate. Psychiatry Res. 2001;101:277-288.
    • (2001) Psychiatry Res. , vol.101 , pp. 277-288
    • Fontaine, K.R.1    Heo, M.2    Harrigan, E.P.3
  • 4
    • 0347596648 scopus 로고    scopus 로고
    • Obesity as a risk factor for antipsychotic noncompliance
    • Weiden PJ, Mackell JA, McDonnell DD. Obesity as a risk factor for antipsychotic noncompliance. Schizophr Res. 2004;66:51-57.
    • (2004) Schizophr Res. , vol.66 , pp. 51-57
    • Weiden, P.J.1    MacKell, J.A.2    McDonnell, D.D.3
  • 5
    • 22044438850 scopus 로고    scopus 로고
    • Reasons for switching between antipsychotics in daily clinical practice
    • Hugenholtz GW, Heerdink ER, Meijer WE, et al. Reasons for switching between antipsychotics in daily clinical practice. Pharmacopsychiatry. 2005;38:122-124.
    • (2005) Pharmacopsychiatry. , vol.38 , pp. 122-124
    • Hugenholtz, G.W.1    Heerdink, E.R.2    Meijer, W.E.3
  • 6
    • 33750057003 scopus 로고    scopus 로고
    • The 5-HT2C receptor and antipsychoticinduced weight gain - Mechanisms and genetics
    • Reynolds GP, Hill MJ, Kirk SL. The 5-HT2C receptor and antipsychoticinduced weight gain - mechanisms and genetics. J Psychopharmacol. 2006;20:15-18.
    • (2006) J Psychopharmacol. , vol.20 , pp. 15-18
    • Reynolds, G.P.1    Hill, M.J.2    Kirk, S.L.3
  • 7
    • 0037097014 scopus 로고    scopus 로고
    • Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism
    • Reynolds GP, Zhang ZJ, Zhang XB. Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism. Lancet. 2002;359:2086-2087.
    • (2002) Lancet. , vol.359 , pp. 2086-2087
    • Reynolds, G.P.1    Zhang, Z.J.2    Zhang, X.B.3
  • 8
    • 17644394540 scopus 로고    scopus 로고
    • Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis
    • Templeman LA, Reynolds GP, Arranz B, et al. Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis. Pharmacogenet Genomics. 2005;15: 195-200.
    • (2005) Pharmacogenet Genomics. , vol.15 , pp. 195-200
    • Templeman, L.A.1    Reynolds, G.P.2    Arranz, B.3
  • 9
    • 62649120576 scopus 로고    scopus 로고
    • Polymorphisms of the LEP- and LEPR gene and obesity in patients using antipsychotic medication
    • Gregoor JG, van der Weide J, Mulder H, et al. Polymorphisms of the LEP- and LEPR gene and obesity in patients using antipsychotic medication. J Clin Psychopharmacol. 2009;29:21-25.
    • (2009) J Clin Psychopharmacol. , vol.29 , pp. 21-25
    • Gregoor, J.G.1    Van Der Weide, J.2    Mulder, H.3
  • 10
    • 34748854911 scopus 로고    scopus 로고
    • The association between HTR2C polymorphisms and obesity in psychiatric patients using antipsychotics: A cross-sectional study
    • Mulder H, Franke B, van der-Beek van der AA, Arends J, et al. The association between HTR2C polymorphisms and obesity in psychiatric patients using antipsychotics: a cross-sectional study. Pharmacogenomics J. 2007;7:318-324.
    • (2007) Pharmacogenomics J. , vol.7 , pp. 318-324
    • Mulder, H.1    Franke, B.2    Van Der-Beek Van Der, A.A.3    Arends, J.4
  • 11
    • 62649090828 scopus 로고    scopus 로고
    • HTR2C gene polymorphisms and the metabolic syndrome in patients with schizophrenia: A replication study
    • Mulder H, Cohen D, Scheffer H, et al. HTR2C gene polymorphisms and the metabolic syndrome in patients with schizophrenia: a replication study. J Clin Psychopharmacol. 2009;29:16-20.
    • (2009) J Clin Psychopharmacol. , vol.29 , pp. 16-20
    • Mulder, H.1    Cohen, D.2    Scheffer, H.3
  • 12
    • 34248592726 scopus 로고    scopus 로고
    • Association of clozapine-induced weight gain with a polymorphism in the leptin promoter region in patients with chronic schizophrenia in a Chinese population
    • Zhang XY, Tan YL, Zhou DF, et al. Association of clozapine-induced weight gain with a polymorphism in the leptin promoter region in patients with chronic schizophrenia in a Chinese population. J Clin Psychopharmacol. 2007;27:246-251.
    • (2007) J Clin Psychopharmacol. , vol.27 , pp. 246-251
    • Zhang, X.Y.1    Tan, Y.L.2    Zhou, D.F.3
  • 13
    • 34548409611 scopus 로고    scopus 로고
    • Association of the HTR2C gene and antipsychotic induced weight gain: A meta-analysis
    • De Luca V, Mueller DJ, de Bartolomeis A, et al. Association of the HTR2C gene and antipsychotic induced weight gain: a meta-analysis. Int J Neuropsychopharmacol. 2007;10:697-704.
    • (2007) Int J Neuropsychopharmacol. , vol.10 , pp. 697-704
    • De Luca, V.1    Mueller, D.J.2    De Bartolomeis, A.3
  • 14
    • 38349056887 scopus 로고    scopus 로고
    • Possible association between the -2548A/G polymorphism of the leptin gene and olanzapine-induced weight gain
    • Kang SG, Lee HJ, Park YM, et al. Possible association between the -2548A/G polymorphism of the leptin gene and olanzapine-induced weight gain. Prog Neuropsychopharmacol Biol Psychiatry. 2008; 32:160-163.
    • (2008) Prog Neuropsychopharmacol Biol Psychiatry. , vol.32 , pp. 160-163
    • Kang, S.G.1    Lee, H.J.2    Park, Y.M.3
  • 15
    • 0033025753 scopus 로고    scopus 로고
    • Decreased plasma leptin levels in lean and obese Zucker rats after treatment with the serotonin reuptake inhibitor fluoxetine
    • Dryden S, Brown M, King P, et al. Decreased plasma leptin levels in lean and obese Zucker rats after treatment with the serotonin reuptake inhibitor fluoxetine. Horm Metab Res. 1999;31:363-366.
    • (1999) Horm Metab Res. , vol.31 , pp. 363-366
    • Dryden, S.1    Brown, M.2    King, P.3
  • 16
    • 0033592646 scopus 로고    scopus 로고
    • The serotonin precursor 5-hydroxytryptophan elevates serum leptin levels in mice
    • Yamada J, Sugimoto Y, Ujikawa M. The serotonin precursor 5-hydroxytryptophan elevates serum leptin levels in mice. Eur J Pharmacol. 1999;383:49-51.
    • (1999) Eur J Pharmacol. , vol.383 , pp. 49-51
    • Yamada, J.1    Sugimoto, Y.2    Ujikawa, M.3
  • 17
    • 33645212072 scopus 로고    scopus 로고
    • Involvement of leptin in hypophagia induced by the serotonin precursor 5-hydroxytryptophan (5-HTP) in mice
    • Yamada J, Sugimoto Y, Ujikawa M. Involvement of leptin in hypophagia induced by the serotonin precursor 5-hydroxytryptophan (5-HTP) in mice. Biol Pharm Bull. 2006;29:557-559.
    • (2006) Biol Pharm Bull. , vol.29 , pp. 557-559
    • Yamada, J.1    Sugimoto, Y.2    Ujikawa, M.3
  • 18
    • 0032718692 scopus 로고    scopus 로고
    • Leptin increases serotonin turnover by inhibition of brain nitric oxide synthesis
    • Calapai G, Corica F, Corsonello A, et al. Leptin increases serotonin turnover by inhibition of brain nitric oxide synthesis. J Clin Invest. 1999;104:975-982.
    • (1999) J Clin Invest. , vol.104 , pp. 975-982
    • Calapai, G.1    Corica, F.2    Corsonello, A.3
  • 19
    • 0034615847 scopus 로고    scopus 로고
    • Intracerebroventricular infusion of leptin decreases serotonin transporter binding sites in the frontal cortex of the rat
    • Charnay Y, Cusin I, Vallet PG, et al. Intracerebroventricular infusion of leptin decreases serotonin transporter binding sites in the frontal cortex of the rat. Neurosci Lett. 2000;283:89-92.
    • (2000) Neurosci Lett. , vol.283 , pp. 89-92
    • Charnay, Y.1    Cusin, I.2    Vallet, P.G.3
  • 20
    • 0035024713 scopus 로고    scopus 로고
    • Leptin receptor immunoreactivity is present in ascending serotonergic and catecholaminergic neurons of the rat
    • Hay-Schmidt A, Helboe L, Larsen PJ. Leptin receptor immunoreactivity is present in ascending serotonergic and catecholaminergic neurons of the rat. Neuroendocrinology. 2001;73:215-226.
    • (2001) Neuroendocrinology. , vol.73 , pp. 215-226
    • Hay-Schmidt, A.1    Helboe, L.2    Larsen, P.J.3
  • 21
    • 44949234587 scopus 로고    scopus 로고
    • Influence of 5-HT2C receptor and leptin gene polymorphisms, smoking and drug treatment on metabolic disturbances in patients with schizophrenia
    • Yevtushenko OO, Cooper SJ, O'Neill R, et al. Influence of 5-HT2C receptor and leptin gene polymorphisms, smoking and drug treatment on metabolic disturbances in patients with schizophrenia. Br J Psychiatry. 2008;192:424-428.
    • (2008) Br J Psychiatry. , vol.192 , pp. 424-428
    • Yevtushenko, O.O.1    Cooper, S.J.2    O'Neill, R.3
  • 23
    • 1842739590 scopus 로고    scopus 로고
    • Adverse metabolic effects associated with atypical antipsychotics: Literature review and clinical implications
    • Melkersson K, Dahl ML. Adverse metabolic effects associated with atypical antipsychotics: literature review and clinical implications. Drugs. 2004;64:701-723.
    • (2004) Drugs. , vol.64 , pp. 701-723
    • Melkersson, K.1    Dahl, M.L.2
  • 24
    • 44949234587 scopus 로고    scopus 로고
    • Influence of 5-HT2C receptor and leptin gene polymorphisms, smoking and drug treatment on metabolic disturbances in patients with schizophrenia
    • Yevtushenko O, Cooper S, O'Neill R, et al. Influence of 5-HT2C receptor and leptin gene polymorphisms, smoking and drug treatment on metabolic disturbances in patients with schizophrenia. Br J Psychiatry. 2008;192:424-428.
    • (2008) Br J Psychiatry. , vol.192 , pp. 424-428
    • Yevtushenko, O.1    Cooper, S.2    O'Neill, R.3
  • 25
    • 0034613398 scopus 로고    scopus 로고
    • Serum leptin levels after central and systemic injection of a serotonin precursor, 5-hydroxytryptophan, in mice
    • Yamada J, Ujikawa M, Sugimoto Y. Serum leptin levels after central and systemic injection of a serotonin precursor, 5-hydroxytryptophan, in mice. Eur J Pharmacol. 2000;406:159-162.
    • (2000) Eur J Pharmacol. , vol.406 , pp. 159-162
    • Yamada, J.1    Ujikawa, M.2    Sugimoto, Y.3
  • 26
    • 0037323842 scopus 로고    scopus 로고
    • Serum leptin levels in patients with premature ejaculation before and after citalopram treatment
    • Atmaca M, Kuloglu M, Tezcan E, et al. Serum leptin levels in patients with premature ejaculation before and after citalopram treatment. BJU Int. 2003;91:252-254.
    • (2003) BJU Int. , vol.91 , pp. 252-254
    • Atmaca, M.1    Kuloglu, M.2    Tezcan, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.