Gene expression reprogramming protects macrophage from septic-induced cell death

Molecular Immunology

Volumn 47, Issue 16, 2010, Pages 2587-2593

  Melo, Edielle Sant'Anna ^a   Barbeiro, Denise F ^a   Gorjão, Renata ^a   Rios, Ester Correia Sarmento ^a   Vasconcelos, Dewton ^a   Velasco, Irineu T ^a   Szabo, Csaba ^b   Curi, Rui ^a   De Lima Salgado, Thais Martins ^a   Soriano, Francisco Garcia ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

Author keywords

Apoptosis; Gene expression; Immunoparalysia; Macrophage; Necrosis; Sepsis

Indexed keywords

CASPASE 3; FAS LIGAND; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CELL ISOLATION; CELL PROTECTION; CONTROLLED STUDY; ENDOTOXEMIA; FLOW CYTOMETRY; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; MACROPHAGE; MALE; MICROARRAY ANALYSIS; MOUSE; NECROSIS; NONHUMAN; NUCLEAR REPROGRAMMING; PRIORITY JOURNAL; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPSIS; SURVIVAL;

ANIMALS; APOPTOSIS; CELL LINEAGE; CELLS, CULTURED; CYTOKINES; GENE EXPRESSION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED BALB C; SEPSIS;

ANIMALIA; MUS;

EID: 78649320055     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2010.06.011     Document Type: Article

References (32)

1. Aldinucci A., Gerlini G., Fossati S., et al. A key role for poly(ADP-ribose) polymerase-1 activity during human dendritic cell maturation. J. Immunol. 2007, 179:305-312.
2. Benjamim C.F., Ferreira S.H., Cunha F.Q. Role of nitric oxide in the failure of neutrophil migration in sepsis. J. Infect. Dis. 2000, 182:214-223.
3. Bergsbaken T., Fink S.L., Cookson B.T. Pyroptosis: host cell death and inflammation. Nat. Rev. 2009, 7:99-109.
4. Bonig H., Packeisen J., Rohne B., et al. Interaction between interleukin 10 and interleukin 6 in human B-cell differentiation. Immunol. Invest. 1998, 27:267-280.
5. Brun-Buisson C. The epidemiology of the systemic inflammatory response. Intensive Care Med. 2000, 26(Suppl. 1):S64-S74.
6. Byrne A., Reen D.J. Lipopolysaccharide induces rapid production of IL-10 by monocytes in the presence of apoptotic neutrophils. J. Immunol. 2002, 168:1968-1977.
7. Carrithers M, Tandon S., Canosa S., et al. Enhanced susceptibility to endotoxic shock and impaired STAT3 signaling in CD31-deficient mice. Am. J. Pathol. 2005, 166:185-196.
8. Cerutti A., Zan H., Schaffer A., et al. CD40 ligand and appropriate cytokines induce switching to IgG, IgA, and IgE and coordinated germinal center and plasmacytoid phenotypic differentiation in a human monoclonal IgM+IgD+ B cell line. J. Immunol. 1998, 160:2145-2157.
9. Chang K.C., Unsinger J., Davis C.G., et al. Multiple triggers of cell death in sepsis: death receptor and mitochondrial-mediated apoptosis. FASEB J. 2007, 21:708-719.
10. Chen M., Zsengeller Z., Xiao C.Y., et al. Mitochondrial-to-nuclear translocation of apoptosis-inducing factor in cardiac myocytes during oxidant stress: potential role of poly (ADP-ribose) polymerase-1. Cardiovasc. Res. 2004, 63:682-688.
11. Coopersmith C.M., Stromberg P.E., Davis C.G., et al. Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and induces gut epithelial cell cycle arrest. Crit. Care Med. 2003, 31:1630-1637.
12. Deng J.C., Cheng G., Newstead M.W., et al. Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M. J. Clin. Invest. 2006, 116:2532-2542.
13. Duddy M.E., Alter A., Bar-Or A. Distinct profiles of human B cell effector cytokines: a role in immune regulation?. J. Immunol. 2004, 172:3422-3427.
14. Fan H., Cook J.A. Molecular mechanisms of endotoxin tolerance. J. Endotoxin Res. 2004, 10:71-84.
15. Fink S.L., Cookson B.T. Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells. Infect. Immun. 2005, 73:1907-1916.
16. Foster S.L., Hargreaves D.C., Medzhitov R. Gene-specific control of inflammation by TLR-induced chromatin modifications. Nature 2007, 447:972-978.
17. Garcia Soriano F., Virag L., Jagtap P., et al. Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat. Med. 2001, 7:108-113.
18. Hoffmann J.A., Kafatos F.C., Janeway C.A., et al. Phylogenetic perspectives in innate immunity. Science 1999, 284:1313-1318.
19. Hotchkiss R.S., Nicholson D.W. Apoptosis and caspases regulate death and inflammation in sepsis. Nat. Rev. Immunol. 2006, 6:813-822.
20. Kobayashi K., Hernandez L.D., Galan J.E., et al. IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 2002, 110:191-202.
21. Lamkanfi M., Festjens N., Declercq W., et al. Caspases in cell survival, proliferation and differentiation. Cell Death Differ. 2007, 14:44-55.
22. McDunn J.E., Muenzer J.T., Rachdi L., et al. Peptide-mediated activation of Akt and extracellular regulated kinase signaling prevents lymphocyte apoptosis. FASEB J. 2007, 22:561-568.
23. Pacher P., Schulz R., Liaudet L., et al. Nitrosative stress and pharmacological modulation of heart failure. Trends Pharmacol. Sci. 2005, 26:302-310.
24. Rios-Santos F., Alves-Filho J.C., Souto F.O., et al. Down-regulation of CXCR2 on neutrophils in severe sepsis is mediated by inducible nitric oxide synthase-derived nitric oxide. Am. J. Respir. Crit. Care Med. 2007, 175:490-497.
25. Roth P., Bartocci A., Stanley E.R. Lipopolysaccharide induces synthesis of mouse colony-stimulating factor-1 in vivo. J. Immunol. 1997, 158:3874-3880.
26. Schultze J.L., Michalak S., Lowne J., et al. Human non-germinal center B cell interleukin (IL)-12 production is primarily regulated by T cell signals CD40 ligand, interferon gamma, and IL-10: role of B cells in the maintenance of T cell responses. J. Exp. Med. 1999, 189:1-12.
27. Soriano F.G., Liaudet L., Szabo E., et al. Resistance to acute septic peritonitis in poly(ADP-ribose) polymerase-1-deficient mice. Shock 2002, 17:286-292.
28. Szabo C., Zingarelli B., O'Connor M., et al. DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:1753-1758.
29. Texereau J., Pene F., Chiche J.D., et al. Importance of hemostatic gene polymorphisms for susceptibility to and outcome of severe sepsis. Crit. Care Med. 2004, 32:S313-319.
30. Torres-Duenas D., Celes M.R., Freitas A., et al. Peroxynitrite mediates the failure of neutrophil migration in severe polymicrobial sepsis in mice. Br. J. Pharmacol. 2007, 152:341-352.
31. Tyurina Y.Y., Basova L.V., Konduru N.V., et al. Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalization and macrophage engulfment: implications for the resolution of inflammation. J. Biol. Chem. 2007, 282:8498-8509.
32. Voll R.E., Herrmann M., Roth E.A., et al. Immunosuppressive effects of apoptotic cells. Nature 1997, 390:350-351.