Emergence of 16S rRNA methylase gene armA and cocarriage of blaIMP-1 in Pseudomonas aeruginosa isolates from South Korea

Diagnostic Microbiology and Infectious Disease

Volumn 68, Issue 4, 2010, Pages 468-470

  Gurung, Mamata ^a   Moon, Dong Chan ^a   Tamang, Migma Dorji ^a   Kim, Jungmin ^a   Lee, Yoo Chul ^a   Seol, Sung Yong ^a   Cho, Dong Taek ^a   Lee, Je Chul ^a  

^a Kyungpook National University School of Medicine   (South Korea)

Author keywords

Lactamase; 16S rRNA methylase; Aminoglycoside modifying enzyme; Carbapenemase

Indexed keywords

AMIKACIN; AZTREONAM; BETA LACTAMASE; BETA LACTAMASE IMP 1; CARBENICILLIN; CEFEPIME; CEFOPERAZONE; CEFOTAXIME; CEFTAZIDIME; CHLORAMPHENICOL; CIPROFLOXACIN; COLISTIN; GATIFLOXACIN; GENTAMICIN; IMIPENEM; ISEPAMICIN; KANAMYCIN; MEROPENEM; MINOCYCLINE; NETILMICIN; NORFLOXACIN; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; RNA 16S; RNA METHYLTRANSFERASE; RNA METHYLTRANSFERASE ARMA; SPECTINOMYCIN; TETRACYCLINE; TOBRAMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; PULSED FIELD GEL ELECTROPHORESIS; SOUTH KOREA;

ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; DRUG RESISTANCE, MULTIPLE, BACTERIAL; HOSPITALS, UNIVERSITY; HUMANS; METHYLTRANSFERASES; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PREVALENCE; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; REPUBLIC OF KOREA; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, DNA;

EID: 78649317056     PISSN: 07328893     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2010.07.021     Document Type: Article

References (16)

1. Bert F., Branger C., Lambert-Zechovsky N. Identification of PSE and OXA β-lactamase genes in Pseudomonas aeruginosa using PCR restriction fragment length polymorphism. J. Antimicrob. Chemother. 2002, 50:11-18.
2. Cho Y.J., Moon D.C., Jin J.S., Choi C.H., Lee Y.C., Lee J.C. Genetic basis of resistance to aminoglycosides in Acinetobacter spp. and spread of armA in Acinetobacter baumannii sequence group 1 in Korean hospitals. Diagn. Microbiol. Infect. Dis. 2009, 64:185-190.
3. Clinical and Laboratory Standards Institute (CLSI) Performance standards for antimicrobial susceptibility testing: 17th informational supplement (M100-S17) 2007, CLSI., Wayne, PA.
4. Doi Y., Yokoyama K., Yamane K., Wachino J., Shibata N., Yagi T., Shibayama K., Kato H., Arakawa Y. Plasmid-mediated 16S rRNA methylase in Serratia marcescens conferring high-level resistance to aminoglycosides. Antimicrob. Agents. Chemother. 2004, 48:491-496.
5. Doi Y., de Oliveira Garcia D., Adams J., Paterson D.L. Coproduction of novel 16S rRNA methylase RmtD and metallo-β-lactamase SPM-1 in a panresistant Pseudomonas aeruginosa isolate from Brazil. Antimicrob. Agents. Chemother. 2007, 51:852-856.
6. Galimand M., Courvalin P., Lambert T. Plasmid-mediated high level resistance to aminoglycosides in Enterobacteriaceae due to 16S rRNA methylation. Antimicrob. Agents. Chemother. 2003, 47:2565-2571.
7. Jeon B.C., Jeong S.H., Bae I.K., Kwon S.B., Lee K., Young D., Lee J.H., Song J.S., Lee S.H. Investigation of a nosocomial outbreak of imipenem-resistant Acinetobacter baumannii producing the OXA-23 β-lactamase in Korea. J. Clin. Microbiol. 2005, 43:2241-2245.
8. Jin J.S., Kwon K.T., Moon D.C., Lee J.C. Emergence of 16S rRNA methylase rmtA in colistin-only-sensitive Pseudomonas aeruginosa in South Korea. Int. J. Antimicrob. Agents. 2009, 33:490-491.
9. Kang H.Y., Kim K.Y., Kim J., Lee J.C., Lee Y.C., Cho D.T., Seol S.Y. Distribution of conjugative-plasmid-mediated 16S rRNA methylase genes among amikacin-resistant Enterobacteriaceae isolates collected in 1995 to 1998 and 2001 to 2006 at a university hospital in South Korea and identification of conjugative plasmids mediating dissemination of 16S rRNA Methylase. J. Clin. Microbiol. 2008, 46:700-706.
10. Lee H., Yong D., Yum J.H., Roh K.H., Lee K., Yamane K., Arakawa Y., Chong Y. Dissemination of 16S rRNA methylase-mediated highly amikacin-resistant isolates of Klebsiella pneumoniae and Acinetobacter baumannii in Korea. Diagn. Microbiol. Infect. Dis. 2006, 56:305-312.
11. Noppe-Leclercq I., Wallet F., Haentjens S., Courcol R., Simonet M. PCR detection of aminoglycoside resistance genes: a rapid molecular typing method for Acinetobacter baumannii. Res. Microbiol. 1999, 150:317-322. Giveup.
12. Pai H., Kim J., Kim J., Lee J.H., Choe K.W., Gotoh N. Carbapenem resistance mechanisms in Pseudomonas aeruginosa clinical isolates. Antimicrob. Agents. Chemother. 2001, 45:480-484.
13. Shi W.F., Jiang J.P., Mi Z.H. Relationship between antimicrobial resistance and aminoglycoside-modifying enzyme gene expressions in Acinetobacter baumannii. Chin. Med. J. 2005, 118:141-145.
14. Wachino J., Yamane K., Shibayama K., Kurokawa H., Shibata N., Suzuki S., Doi Y., Kimura K., Ike Y., Arakawa Y. Novel plasmid-mediated 16S rRNA methylase, RmtC, found in a Proteus mirabilis isolate demonstrating extraordinary high-level resistance against various aminoglycosides. Antimicrob. Agents. Chemother. 2006, 50:178-184.
15. Yan J.J., Wu J.J., Ko W.C., Tsai S.H., Chuang C.L., Wu H.M., Lu Y.J., Li J.D. Plasmid-mediated 16S rRNA methylases conferring high-level aminoglycoside resistance in Escherichia coli and Klebsiella pneumoniae isolates from Taiwanese hospitals. J. Antimicrob. Chemother. 2004, 54:1007-1012.
16. Yokoyama K., Doi Y., Yamane K., Kurokawa H., Shibata N., Shibayama K., Yagi T., Kato H., Arakawa Y. Acquisition of 16S rRNA methylase gene in Pseudomonas aeruginosa. Lancet 2003, 362:1888-1893.