Investigation of a nosocomial outbreak of imipenem-resistant Acinetobacter baumannii producing the OXA-23 β-lactamase in Korea

Journal of Clinical Microbiology

Volumn 43, Issue 5, 2005, Pages 2241-2245

  Jeon, Byung Chan ^a   Jeong, Seok Hoon ^a   Bae, Il Kwon ^a   Kwon, Su Bong ^a   Lee, Kyungwon ^b   Young, Dongeun ^b   Lee, Jung Hun ^c   Song, Jae Seok ^c   Lee, Sang Hee ^c  

^a Kosin University College of Medicine   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

^c Myong Ji University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMPICILLIN; ANTIBIOTIC AGENT; AZTREONAM; CARBAPENEM DERIVATIVE; CEFALOTIN; CEFEPIME; CEFOPERAZONE; CEFOTAXIME; CEFOXITIN; CEFTAZIDIME; CEPHALOSPORIN DERIVATIVE; CEPHAMYCIN DERIVATIVE; CIPROFLOXACIN; COTRIMOXAZOLE; GENTAMICIN; IMIPENEM; MONOBACTAM DERIVATIVE; NITROCEFIN; PENICILLIN DERIVATIVE; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; SULTAMICILLIN; TETRACYCLINE; TOBRAMYCIN;

ACINETOBACTER BAUMANNII; AMPLICON; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; CLOVERLEAF SYNERGY TEST; EPIDEMIC; GENE SEQUENCE; HOSPITAL INFECTION; INTENSIVE CARE UNIT; ISOELECTRIC FOCUSING; MEDICINE; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NEUROLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; SEQUENCE ANALYSIS; SOUTH KOREA; SURGICAL WARD; UROLOGY;

ACINETOBACTER BAUMANNII; BASE SEQUENCE; BETA-LACTAMASES; CONJUGATION, GENETIC; CROSS INFECTION; DNA PRIMERS; DRUG RESISTANCE, MICROBIAL; GENOTYPE; HUMANS; IMIPENEM; KOREA; MICROBIAL SENSITIVITY TESTS;

ACINETOBACTER BAUMANNII; BACTERIA (MICROORGANISMS);

EID: 18544386411     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.43.5.2241-2245.2005     Document Type: Article

References (22)

1. Afzal-Shah, M., N. Woodford, and D. M. Livermore. 2001. Characterization of OXA-25, OXA-26, and OXA-27 molecular class D β-lactamase associated with carbapenem resistance in clinical isolates of Acinetobacter baumannii. Antimicrob. Agents Chemother. 45:583-588.
2. Bonnet, R., H. Marchandin, C. Chanal, D. Sirot, R. Labia, C. De Champs, E. Jumas-Bilak, and J. Sirot. 2002. Chromosome-encoded class D-lactamase OXA-23 in Proteus mirabilis. Antimicrob. Agents Chemother. 46:2004-2006.
3. Bou, G., A. Oliver, and J. Martínez-Beltrán. 2000. OXA-24, a novel class D β-lactamase with carbapenemase activity in an Acinetobacter baumannii clinical strain. Antimicrob. Agents Chemother. 44:1556-1561.
4. Chastre, J., and J. L. Trouillet. 2000. Problem pathogens (Pseudomonas aeruginosa and Acinetobacter). Semin. Respir. Infect. 15:287-298.
5. Dalla-Costa, L. M., J. M. Coelho, H. A. P. H. M. Souza, M. E. S. Castro, C. J. N. Stier, K. L. Bragagnolo, A. Rea-Neto, S. R. Penteado-Filho, D. M. Livermore, and N. Woodford. 2003. Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil. J. Clin. Microbiol. 41:3403-3406.
6. Donald, H. M., W. Scaife, S. G. B. Amyes, and H.-K. Young. 2000. Sequence analysis of ARI-1, a novel OXA β-lactamase, responsible for imipenem resistance in Acinetobacter baumannii 6B92. Antimicrob. Agents Chemother. 44:196-199.
7. Héritier, C., L. Poirel, D. Aubert, and P. Nordmann. 2003. Genetic and functional analysis of the chromosome-encoded carbapenem-hydrolyzing oxacillinase OXA-40 of Acinetobacter baumannii. Antimicrob. Agents Chemother. 47:268-273.
8. Hornstein, M., C. Sautjeau-Rostoker, J. Péduzzi, A. Vessières, L. T. H. Hong, M. Barthélémy, M. Scavizzi, and R. Labia. 1997. Oxacillin-hydrolyzing β-lactamase involved in resistance to imipenem in Acinetobacter baumannii. FEMS Microbiol. Lett. 153:333-339.
9. Jeong, S. H., I. K. Bae, J. H. Lee, S. H. Sohn, G. H. Kang, G. J. Jeon, Y. H. Kim, B. C. Jeong, and S. H. Lee. 2004. Molecular characterization of extended-spectrum β-lactamases produced by clinical isolates of Klebsiella pneumoniae and Escherichia coli from a Korean nationwide survey. J. Clin. Microbiol. 42:2902-2906.
10. Jeong, S. H., K. Lee, Y. Chong, J. H. Yum, S. H. Lee, H. J. Choi, J. M. Kim, K. H. Park, B. H. Han, S. W. Lee, and T. S. Jeong. 2003. Characterization of a new integron containing VIM-2, a metallo-β-lactamase gene cassette, in a clinical isolate of Enterobacter cloacae. J. Antimicrob. Chemother. 51:397-400.
11. Lee, K., Y. Chong, H. B. Shin, Y. A. Kim, D. Young, and J. H. Yum. 2000. Modified Hodhe and EDTA-disk synergy tests to screen metallo-β-lactamase- producing strains of Pseudomonas and Acinetobacter species. Clin. Microbiol. Infect. 7:88-102.
12. CMY-11, an AmpC-type plasmid-mediated β-lactamase gene in a Korean clinical isolate of Escherichia coli. J. Antimicrob. Chemother. 49:269-273.
13. Lee, S. H., J. Y. Kim, S. H. Shin, S. K. Lee, M. M. Choi, I. Y. Lee, Y. B. Kim, J. Y. Cho, W. Jin, and K. J. Lee. 2001. Restriction fragment length dimorphism-PCR method for the detection of extended-spectrum β-lactamases unrelated to TEM- and SHV-types. FEMS Microbiol. Lett. 200:157-161.
14. Livermore, D. M. 2002. The impact of carbapenemases on antimicrobial development and therapy. Curr. Opin. Investig. Drugs 3:218-224.
15. National Committee for Clinical Laboratory Standards. 2003. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standards, 6th ed. Document M7-A6. National Committee for Clinical Laboratory Standards, Wayne, Pa.
16. Sambrook, J., and D. W. Russell. 2001. Extraction and purification of plasmid and screening of bacterial colonies by hybridization, p. 1.40-1.92. In J. Argentine, N. Irwin, K. A. Jassen, S. C. M. Zierler, N. McInerny, D. Brown, and S. Schaefer (ed.), Molecular cloning: a laboratory manual, 3rd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
17. Schreckenberger, P. C., and A. Von Graevenitz. 1999. Acinetobacter, Achromobacter, Alcaligenes, Moraxella, Methylobacterium, and other non-fermentative gram-negative rods, p. 539-560. In P. R. Murray, E. J. Baron, M. A. Pfaller, F. C. Tenover, and R. H. Yolken (ed.), Manual of clinical microbiology, 7th ed. American Society for Microbiology, Washington, D.C.
18. Silva, G. J., S. Quinteira, E. Bértolo, J. C. Sousa, L. Gallego, A. Duarte, and L. Peixe. 2004. Long-term dissemination of an OXA-40 carbapenemase-producing Acinetobacter baumannii clone in the Iberian Peninsula. J. Antimicrob. Chemother. 54:255-258.
19. Simor, A. E., S. F. Bradley, L. J. Strausbaugh, K. Crossley, and L. E. Nicolle. 2002. An outbreak due to multiresistant Acinetobacter baumannii in a burn unit: risk factors for acquisition and management. Infect. Control Hosp. Epidemiol. 23:261-267.
20. Tenover, F. C., R. D. Arbeit, R. V. Goering, P. A. Mickelsen, B. E. Murray, D. H. Persing, and B. Swaminathan. 1995. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis criteria for bacterial strain typing. J. Clin. Microbiol. 33:2233-2239.
21. Yong, D., J. H. Shin, S. Kim, S. Kim, Y. Lim, H. H. Yum, K. Lee, Y. Chong, and A. Bauernfeind. 2003. High prevalence of PER-1 extended-spectrum β-lactamase-producing Acinetobacter spp. in Korea. Antimicrob. Agents Chemother. 47:1749-1751.
22. Zarrilli, R., M. Crispino, M. Bagattini, E. Barretta, A. D. Popolo, M. Triassi, and P. Vollari. 2004. Molecular epidemiology of sequential outbreaks of Acinetobacter baumannii in an intensive care unit shows the emergence of carbapenem resistance. J. Clin. Microbiol. 42:946-953.