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Volumn 299, Issue 6, 2010, Pages

Voltage-gated potassium channel Kv1.3 blocker as a potential treatment for rat anti-glomerular basement membrane glomerulonephritis

Author keywords

Crescentic glomerulonephritis; Flow cytometric analysis; WKY rats

Indexed keywords

5 (4 PHENYLBUTOXY)PSORALEN; GLOMERULUS BASEMENT MEMBRANE ANTIBODY; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KV1.3; PSORALEN DERIVATIVE; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

EID: 78649313283     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00374.2010     Document Type: Article
Times cited : (31)

References (62)
  • 1
    • 69449091010 scopus 로고    scopus 로고
    • Urinary CD4+ effector memory T cells reflect renal disease activity in antineutrophil cytoplasmic antibody-associated vasculitis
    • Abdulahad WH, Kallenberg CG, Limburg PC, Stegeman CA. Urinary CD4+ effector memory T cells reflect renal disease activity in antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheum 60: 2830-2838, 2009.
    • (2009) Arthritis Rheum , vol.60 , pp. 2830-2838
    • Abdulahad, W.H.1    Kallenberg, C.G.2    Limburg, P.C.3    Stegeman, C.A.4
  • 2
    • 34648846035 scopus 로고    scopus 로고
    • CD4- positive effector memory T cells participate in disease expression in ANCA-associated vasculitis
    • Abdulahad WH, Stegeman CA, Limburg PC, Kallenberg CG. CD4- positive effector memory T cells participate in disease expression in ANCA-associated vasculitis. Ann NY Acad Sci 1107: 22-31, 2007.
    • (2007) Ann NY Acad Sci , vol.1107 , pp. 22-31
    • Abdulahad, W.H.1    Stegeman, C.A.2    Limburg, P.C.3    Kallenberg, C.G.4
  • 3
    • 0035470835 scopus 로고    scopus 로고
    • Infiltration of canonical Vgamma4/Vdelta1 gammadelta T cells in an adriamycin-induced progressive renal failure model
    • Ando T, Wu H, Watson D, Hirano T, Hirakata H, Fujishima M, Knight JF. Infiltration of canonical Vgamma4/Vdelta1 gammadelta T cells in an adriamycin-induced progressive renal failure model. J Immunol 167: 3740-3745, 2001. (Pubitemid 32910819)
    • (2001) Journal of Immunology , vol.167 , Issue.7 , pp. 3740-3745
    • Ando, T.1    Wu, H.2    Watson, D.3    Hirano, T.4    Hirakata, H.5    Fujishima, M.6    Knight, J.F.7
  • 4
    • 46049093364 scopus 로고    scopus 로고
    • Th17 Cells and autoimmune encephalomyelitis (EAE/MS)
    • Aranami T, Yamamura T. Th17 Cells and autoimmune encephalomyelitis (EAE/MS). Allergol Int 57: 115-120, 2008.
    • (2008) Allergol Int , vol.57 , pp. 115-120
    • Aranami, T.1    Yamamura, T.2
  • 5
    • 60749095669 scopus 로고    scopus 로고
    • Renal ischemia-reperfusion leads to long term infiltration of activated and effector-memory T lymphocytes
    • Ascon M, Ascon DB, Liu M, Cheadle C, Sarkar C, Racusen L, Hassoun HT, Rabb H. Renal ischemia-reperfusion leads to long term infiltration of activated and effector-memory T lymphocytes. Kidney Int 75: 526-535, 2009.
    • (2009) Kidney Int , vol.75 , pp. 526-535
    • Ascon, M.1    Ascon, D.B.2    Liu, M.3    Cheadle, C.4    Sarkar, C.5    Racusen, L.6    Hassoun, H.T.7    Rabb, H.8
  • 7
    • 34248599015 scopus 로고    scopus 로고
    • Targeting effector memory T cells with the small molecule Kv1.3 blocker PAP-1 suppresses allergic contact dermatitis
    • Azam P, Sankaranarayanan A, Homerick D, Griffey S, Wulff H. Targeting effector memory T cells with the small molecule Kv1.3 blocker PAP-1 suppresses allergic contact dermatitis. J Invest Dermatol 127: 1419-1429, 2007.
    • (2007) J Invest Dermatol , vol.127 , pp. 1419-1429
    • Azam, P.1    Sankaranarayanan, A.2    Homerick, D.3    Griffey, S.4    Wulff, H.5
  • 12
    • 0030720015 scopus 로고    scopus 로고
    • Ion channels in the immune system as targets for immunosuppression
    • DOI 10.1016/S0958-1669(97)80130-9
    • Cahalan MD, Chandy KG. Ion channels in the immune system as targets for immunosuppression. Curr Opin Biotechnol 8: 749-756, 1997. (Pubitemid 27517253)
    • (1997) Current Opinion in Biotechnology , vol.8 , Issue.6 , pp. 749-756
    • Cahalan, M.D.1    Chandy, K.G.2
  • 14
    • 33748945382 scopus 로고    scopus 로고
    • Binding site of a novel Kv1.5 blocker: A "foot in the door" against atrial fibrillation
    • Decher N, Kumar P, Gonzalez T, Pirard B, Sanguinetti MC. Binding site of a novel Kv1.5 blocker: a "foot in the door" against atrial fibrillation. Mol Pharmacol 70: 1204-1211, 2006.
    • (2006) Mol Pharmacol , vol.70 , pp. 1204-1211
    • Decher, N.1    Kumar, P.2    Gonzalez, T.3    Pirard, B.4    Sanguinetti, M.C.5
  • 16
    • 55249118612 scopus 로고    scopus 로고
    • Dendritic cells facilitate accumulation of IL-17 T cells in the kidney following acute renal obstruction
    • Dong X, Bachman LA, Miller MN, Nath KA, Griffin MD. Dendritic cells facilitate accumulation of IL-17 T cells in the kidney following acute renal obstruction. Kidney Int 74: 1294-1309, 2008.
    • (2008) Kidney Int , vol.74 , pp. 1294-1309
    • Dong, X.1    Bachman, L.A.2    Miller, M.N.3    Nath, K.A.4    Griffin, M.D.5
  • 17
    • 0034502715 scopus 로고    scopus 로고
    • Flow cytometric characterization of lesional T cells in psoriasis: Intracellular cytokine and surface antigen expression indicates an activated, memory/effector type 1 immunophenotype
    • DOI 10.1007/s004030000167
    • Friedrich M, Krammig S, Henze M, Docke WD, Sterry W, Asadullah K. Flow cytometric characterization of lesional T cells in psoriasis: intracellular cytokine and surface antigen expression indicates an activated, memory/effector type 1 immunophenotype. Arch Dermatol Res 292: 519-521, 2000. (Pubitemid 32112810)
    • (2000) Archives of Dermatological Research , vol.292 , Issue.10 , pp. 519-521
    • Friedrich, M.1    Krammig, S.2    Henze, M.3    Docke, W.-D.4    Sterry, W.5    Asadullah, K.6
  • 19
    • 0031570101 scopus 로고    scopus 로고
    • Crucial role of CD8- positive lymphocytes in glomerular expression of ICAM-1 and cytokines in crescentic glomerulonephritis of WKY rats
    • Fujinaka H, Yamamoto T, Feng L, Kawasaki K, Yaoita E, Hirose S, Goto S, Wilson CB, Uchiyama M, Kihara I. Crucial role of CD8- positive lymphocytes in glomerular expression of ICAM-1 and cytokines in crescentic glomerulonephritis of WKY rats. J Immunol 158: 4978-4983, 1997.
    • (1997) J Immunol , vol.158 , pp. 4978-4983
    • Fujinaka, H.1    Yamamoto, T.2    Feng, L.3    Kawasaki, K.4    Yaoita, E.5    Hirose, S.6    Goto, S.7    Wilson, C.B.8    Uchiyama, M.9    Kihara, I.10
  • 21
    • 0035995341 scopus 로고    scopus 로고
    • Decreased CD4 lymphocyte count as a marker predicting high mortality rate in managing ANCA related rapidly progressive glomerulonephritis
    • Furuta T, Hotta O, Horigome I, Chiba S, Noshiro H, Miyazaki M, Satoh M, Honda S, Taguma Y. Decreased CD4 lymphocyte count as a marker predicting high mortality rate in managing ANCA related rapidly progressive glomerulonephritis. Nephron 91: 601-605, 2002.
    • (2002) Nephron , vol.91 , pp. 601-605
    • Furuta, T.1    Hotta, O.2    Horigome, I.3    Chiba, S.4    Noshiro, H.5    Miyazaki, M.6    Satoh, M.7    Honda, S.8    Taguma, Y.9
  • 23
    • 68949208498 scopus 로고    scopus 로고
    • Blockade of T-lymphocyte KCa3.1 and Kv13 channels as novel immunosuppression strategy to prevent kidney allograft rejection
    • Grgic I, Wulff H, Eichler I, Flothmann C, Kohler R, Hoyer J. Blockade of T-lymphocyte KCa3.1 and Kv13 channels as novel immunosuppression strategy to prevent kidney allograft rejection. Transplant Proc 41: 2601-2606, 2009.
    • (2009) Transplant Proc , vol.41 , pp. 2601-2606
    • Grgic, I.1    Wulff, H.2    Eichler, I.3    Flothmann, C.4    Kohler, R.5    Hoyer, J.6
  • 24
    • 77951250058 scopus 로고    scopus 로고
    • KCNQ potassium channels: New targets for pulmonary vasodilator drugs?
    • Gurney AM, Joshi S, Manoury B. KCNQ potassium channels: new targets for pulmonary vasodilator drugs? Adv Exp Med Biol 661: 405-417.
    • Adv Exp Med Biol , vol.661 , pp. 405-417
    • Gurney, A.M.1    Joshi, S.2    Manoury, B.3
  • 26
    • 0031155269 scopus 로고    scopus 로고
    • IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/Ipr mice
    • Haas C, Ryffel B, Le Hir M. IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/Ipr mice. J Immunol 158: 5484-5491, 1997.
    • (1997) J Immunol , vol.158 , pp. 5484-5491
    • Haas, C.1    Ryffel, B.2    Le Hir, M.3
  • 27
    • 0032522778 scopus 로고    scopus 로고
    • IFN-gamma receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB X NZW)F1 mice
    • Haas C, Ryffel B, Le Hir M. IFN-gamma receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB X NZW)F1 mice. J Immunol 160: 3713-3718, 1998.
    • (1998) J Immunol , vol.160 , pp. 3713-3718
    • Haas, C.1    Ryffel, B.2    Le Hir, M.3
  • 28
    • 1842525944 scopus 로고    scopus 로고
    • + channel Kv1.3 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid inducible kinase SGK1
    • + channel Kv1.3 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid inducible kinase SGK1. J Cell Physiol 199: 194-199, 2004.
    • (2004) J Cell Physiol , vol.199 , pp. 194-199
    • Henke, G.1    Maier, G.2    Wallisch, S.3    Boehmer, C.4    Lang, F.5
  • 29
    • 0019371079 scopus 로고
    • Abrogation of macrophage-dependent injury in experimental glomerulonephritis in the rabbit. Use of an antimacrophage serum
    • Holdsworth SR, Neale TJ, Wilson CB. Abrogation of macrophage-dependent injury in experimental glomerulonephritis in the rabbit. Use of an antimacrophage serum. J Clin Invest 68: 686-698, 1981.
    • (1981) J Clin Invest , vol.68 , pp. 686-698
    • Holdsworth, S.R.1    Neale, T.J.2    Wilson, C.B.3
  • 31
    • 0037378759 scopus 로고    scopus 로고
    • Interferon-gamma augments acute macrophage-mediated renal injury via a glucocorticoid-sensitive mechanism
    • Ikezumi Y, Atkins RC, Nikolic-Paterson DJ. Interferon-gamma augments acute macrophage-mediated renal injury via a glucocorticoid-sensitive mechanism. J Am Soc Nephrol 14: 888-898, 2003.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 888-898
    • Ikezumi, Y.1    Atkins, R.C.2    Nikolic-Paterson, D.J.3
  • 32
  • 33
    • 0032984190 scopus 로고    scopus 로고
    • IFN-gamma mediates crescent formation and cell-mediated immune injury in murine glomerulonephritis
    • Kitching AR, Holdsworth SR, Tipping PG. IFN-gamma mediates crescent formation and cell-mediated immune injury in murine glomerulonephritis. J Am Soc Nephrol 10: 752-759, 1999.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 752-759
    • Kitching, A.R.1    Holdsworth, S.R.2    Tipping, P.G.3
  • 35
    • 50949116632 scopus 로고    scopus 로고
    • Regulation of IL-17 in human CCR6+ effector memory T cells
    • Liu H, Rohowsky-Kochan C. Regulation of IL-17 in human CCR6+ effector memory T cells. J Immunol 180: 7948-7957, 2008.
    • (2008) J Immunol , vol.180 , pp. 7948-7957
    • Liu, H.1    Rohowsky-Kochan, C.2
  • 37
    • 0035336183 scopus 로고    scopus 로고
    • Mechanisms of the antimetastatic effect in the liver and of the hepatocyte injury induced by alpha-galactosylceramide in mice
    • Nakagawa R, Nagafune I, Tazunoki Y, Ehara H, Tomura H, Iijima R, Motoki K, Kamishohara M, Seki S. Mechanisms of the antimetastatic effect in the liver and of the hepatocyte injury induced by alpha-galactosylceramide in mice. J Immunol 166: 6578-6584, 2001.
    • (2001) J Immunol , vol.166 , pp. 6578-6584
    • Nakagawa, R.1    Nagafune, I.2    Tazunoki, Y.3    Ehara, H.4    Tomura, H.5    Iijima, R.6    Motoki, K.7    Kamishohara, M.8    Seki, S.9
  • 40
    • 35548988104 scopus 로고    scopus 로고
    • Pharmacokinetics, toxicity, and functional studies of the selective Kv1.3 channel blocker 5-(4-phenoxybutoxy)psoralen in rhesus macaques
    • Pereira LE, Villinger F, Wulff H, Sankaranarayanan A, Raman G, Ansari AA. Pharmacokinetics, toxicity, and functional studies of the selective Kv1.3 channel blocker 5-(4-phenoxybutoxy)psoralen in rhesus macaques. Exp Biol Med (Maywood) 232: 1338-1354, 2007.
    • (2007) Exp Biol Med (Maywood) , vol.232 , pp. 1338-1354
    • Pereira, L.E.1    Villinger, F.2    Wulff, H.3    Sankaranarayanan, A.4    Raman, G.5    Ansari, A.A.6
  • 41
    • 68049086921 scopus 로고    scopus 로고
    • SnapShot: Effector and memory T cell differentiation
    • Pipkin ME, Rao A. SnapShot: effector and memory T cell differentiation. Cell 138: 606 e601-602, 2009.
    • (2009) Cell , vol.138
    • Pipkin, M.E.1    Rao, A.2
  • 42
    • 0033567013 scopus 로고    scopus 로고
    • Increased susceptibility to immunologically mediated glomerulonephritis in IFN-gamma- deficient mice
    • Ring GH, Dai Z, Saleem S, Baddoura FK, Lakkis FG. Increased susceptibility to immunologically mediated glomerulonephritis in IFN-gamma- deficient mice. J Immunol 163: 2243-2248, 1999.
    • (1999) J Immunol , vol.163 , pp. 2243-2248
    • Ring, G.H.1    Dai, Z.2    Saleem, S.3    Baddoura, F.K.4    Lakkis, F.G.5
  • 44
    • 0037338619 scopus 로고    scopus 로고
    • Effector T cells and macrophages in urine as a hallmark of systemic vasculitis accompanied by crescentic glomerulonephritis
    • Sakatsume M, Gejyo F. Effector T cells and macrophages in urine as a hallmark of systemic vasculitis accompanied by crescentic glomerulonephritis. Nephrol Dial Transplant 18: 607-609, 2003.
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 607-609
    • Sakatsume, M.1    Gejyo, F.2
  • 46
    • 35549003579 scopus 로고    scopus 로고
    • Regulation of interferon-gamma during innate and adaptive immune responses
    • Schoenborn JR, Wilson CB. Regulation of interferon-gamma during innate and adaptive immune responses. Adv Immunol 96: 41-101, 2007.
    • (2007) Adv Immunol , vol.96 , pp. 41-101
    • Schoenborn, J.R.1    Wilson, C.B.2
  • 47
    • 0017884764 scopus 로고
    • A mononuclear cell component in experimental immunological glomerulonephritis
    • Schreiner GF, Cotran RS, Pardo V, Unanue ER. A mononuclear cell component in experimental immunological glomerulonephritis. J Exp Med 147: 369-384, 1978.
    • (1978) J Exp Med , vol.147 , pp. 369-384
    • Schreiner, G.F.1    Cotran, R.S.2    Pardo, V.3    Unanue, E.R.4
  • 48
    • 0041381363 scopus 로고    scopus 로고
    • + effector and memory T cell generation
    • DOI 10.1038/ni969
    • Seder RA, Ahmed R. Similarities and differences in CD4+ and CD8+ effector and memory T cell generation. Nat Immunol 4: 835-842, 2003. (Pubitemid 37098653)
    • (2003) Nature Immunology , vol.4 , Issue.9 , pp. 835-842
    • Seder, R.A.1    Ahmed, R.2
  • 50
    • 0028084439 scopus 로고
    • Interleukin-1 receptor antagonist ameliorates experimental anti-glomerular basement membrane antibody-associated glomerulonephritis
    • Tang WW, Feng L, Vannice JL, Wilson CB. Interleukin-1 receptor antagonist ameliorates experimental anti-glomerular basement membrane antibody-associated glomerulonephritis. J Clin Invest 93: 273-279, 1994.
    • (1994) J Clin Invest , vol.93 , pp. 273-279
    • Tang, W.W.1    Feng, L.2    Vannice, J.L.3    Wilson, C.B.4
  • 51
    • 33646370482 scopus 로고    scopus 로고
    • T cells in crescentic glomerulonephritis
    • Tipping PG, Holdsworth SR. T cells in crescentic glomerulonephritis. J Am Soc Nephrol 17: 1253-1263, 2006.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1253-1263
    • Tipping, P.G.1    Holdsworth, S.R.2
  • 52
    • 0024565924 scopus 로고
    • Modulation of antibody-mediated glomerular injury in vivo by bacterial lipopolysaccharide, tumor necrosis factor, and IL-1
    • Tomosugi NI, Cashman SJ, Hay H, Pusey CD, Evans DJ, Shaw A, Rees AJ. Modulation of antibody-mediated glomerular injury in vivo by bacterial lipopolysaccharide, tumor necrosis factor, and IL-1. J Immunol 142: 3083-3090, 1989.
    • (1989) J Immunol , vol.142 , pp. 3083-3090
    • Tomosugi, N.I.1    Cashman, S.J.2    Hay, H.3    Pusey, C.D.4    Evans, D.J.5    Shaw, A.6    Rees, A.J.7
  • 54
    • 0036263328 scopus 로고    scopus 로고
    • Characterization of the T-cell response to coxsackievirus B4: Evidence that effector memory cells predominate in patients with type 1 diabetes
    • Varela-Calvino R, Ellis R, Sgarbi G, Dayan CM, Peakman M. Characterization of the T-cell response to coxsackievirus B4: evidence that effector memory cells predominate in patients with type 1 diabetes. Diabetes 51: 1745-1753, 2002.
    • (2002) Diabetes , vol.51 , pp. 1745-1753
    • Varela-Calvino, R.1    Ellis, R.2    Sgarbi, G.3    Dayan, C.M.4    Peakman, M.5
  • 60
    • 33750276090 scopus 로고    scopus 로고
    • Novel anticonvulsant drugs targeting voltage-dependent ion channels
    • Wuttke TV, Lerche H. Novel anticonvulsant drugs targeting voltage-dependent ion channels. Expert Opin Investig Drugs 15: 1167-1177, 2006.
    • (2006) Expert Opin Investig Drugs , vol.15 , pp. 1167-1177
    • Wuttke, T.V.1    Lerche, H.2
  • 61
    • 0029977755 scopus 로고    scopus 로고
    • Molecular cloning of a glibenclamide-sensitive, voltage-gated potassium channel expressed in rabbit kidney
    • Yao X, Chang AY, Boulpaep EL, Segal AS, Desir GV. Molecular cloning of a glibenclamide-sensitive, voltage-gated potassium channel expressed in rabbit kidney. J Clin Invest 97: 2525-2533, 1996.
    • (1996) J Clin Invest , vol.97 , pp. 2525-2533
    • Yao, X.1    Chang, A.Y.2    Boulpaep, E.L.3    Segal, A.S.4    Desir, G.V.5


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