-
1
-
-
0031561476
-
Protein tyrosine kinases and cancer
-
Dec. 9
-
Kolibaba, K. S.; Druker, B. J. Protein tyrosine kinases and cancer. Biochim Biophys Acta 1997 Dec. 9, 1333 (3), F217-F248.
-
(1997)
Biochim. Biophys. Acta
, vol.1333
, Issue.3
-
-
Kolibaba, K.S.1
Druker, B.J.2
-
2
-
-
0032478998
-
Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival
-
Jun. 3
-
Rubin Grandis, J.; Melhem, M. F.; Gooding, W. E.; Day, R.; Holst, V. A.; Wagener, M. M.; Drenning, S. D.; Tweardy, D. J. Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival. J Natl Cancer Inst 1998 Jun. 3, 90 (11), 824-832.
-
(1998)
J. Natl. Cancer Inst.
, vol.90
, Issue.11
, pp. 824-832
-
-
Grandis, R.J.1
Melhem, M.F.2
Gooding, W.E.3
Day, R.4
Holst, V.A.5
Wagener, M.M.6
Drenning, S.D.7
Tweardy, D.J.8
-
3
-
-
0037115674
-
Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma
-
Dec. 15
-
Ang, K. K.; Berkey, B. A.; Tu, X.; Zhang, H. Z.; Katz, R.; Hammond, E. H.; Fu, K. K.; Milas, L. Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma. Cancer Res 2002 Dec. 15, 62 (24), 7350-7356.
-
(2002)
Cancer Res.
, vol.62
, Issue.24
, pp. 7350-7356
-
-
Ang, K.K.1
Berkey, B.A.2
Tu, X.3
Zhang, H.Z.4
Katz, R.5
Hammond, E.H.6
Fu, K.K.7
Milas, L.8
-
4
-
-
33645048171
-
Prognostic value of an activation state marker for epidermal growth factor receptor in tissue microarrays of head and neck cancer
-
Mar. 1
-
Kong, A.; Leboucher, P.; Leek, R.; Calleja, V.; Winter, S.; Harris, A.; Parker, P. J.; Larijani, B. Prognostic value of an activation state marker for epidermal growth factor receptor in tissue microarrays of head and neck cancer. Cancer Res 2006 Mar. 1, 66 (5), 2834-2843.
-
(2006)
Cancer Res.
, vol.66
, Issue.5
, pp. 2834-2843
-
-
Kong, A.1
Leboucher, P.2
Leek, R.3
Calleja, V.4
Winter, S.5
Harris, A.6
Parker, P.J.7
Larijani, B.8
-
5
-
-
33746929465
-
Immunohistochemical expression of EGFR and p-EGFR in oral squamous cell carcinomas
-
Hiraishi, Y.; Wada, T.; Nakatani, K.; Negoro, K.; Fujita, S. Immunohistochemical expression of EGFR and p-EGFR in oral squamous cell carcinomas. Pathol Oncol Res 2006, 12 (2), 87-91.
-
(2006)
Pathol. Oncol. Res.
, vol.12
, Issue.2
, pp. 87-91
-
-
Hiraishi, Y.1
Wada, T.2
Nakatani, K.3
Negoro, K.4
Fujita, S.5
-
6
-
-
33749035470
-
Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting
-
Sep. 1
-
Sok, J. C.; Coppelli, F. M.; Thomas, S. M.; Lango, M. N.; Xi, S.; Hunt, J. L.; Freilino, M. L.; Graner, M. W.; Wikstrand, C. J.; Bigner, D. D.; Gooding, W. E.; Furnari, F. B.; Grandis, J. R. Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting. Clin Cancer Res 2006 Sep. 1, 12 (17), 5064-5073.
-
(2006)
Clin. Cancer Res.
, vol.12
, Issue.17
, pp. 5064-5073
-
-
Sok, J.C.1
Coppelli, F.M.2
Thomas, S.M.3
Lango, M.N.4
Xi, S.5
Hunt, J.L.6
Freilino, M.L.7
Graner, M.W.8
Wikstrand, C.J.9
Bigner, D.D.10
Gooding, W.E.11
Furnari, F.B.12
Grandis, J.R.13
-
7
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
May 12
-
Slamon, D. J.; Godolphin, W.; Jones, L. A.; Holt, J. A.; Wong, S. G.; Keith, D. E.; Levin, W. J.; Stuart, S. G.; Udove, J.; Ullrich, A.; Press, M. F. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 1989 May 12, 244 (4905), 707-712.
-
(1989)
Science
, vol.244
, Issue.4905
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
Press, M.F.11
-
8
-
-
0142059890
-
Molecular mechanism for a role of SHP2 in epidermal growth factor receptor signaling
-
Nov
-
Agazie, Y. M.; Hayman, M. J. Molecular mechanism for a role of SHP2 in epidermal growth factor receptor signaling. Mol Cell Biol 2003 Nov, 23 (21), 7875-7886.
-
(2003)
Mol Cell. Biol.
, vol.23
, Issue.21
, pp. 7875-7886
-
-
Agazie, Y.M.1
Hayman, M.J.2
-
9
-
-
33645301012
-
Mutations in the tyrosine kinase domain of the EGFR gene are rare in synovial sarcoma
-
Apr
-
Bode, B.; Frigerio, S.; Behnke, S.; Senn, B.; Odermatt, B.; Zimmermann, D. R.; Moch, H. Mutations in the tyrosine kinase domain of the EGFR gene are rare in synovial sarcoma. Mod Pathol 2006 Apr, 19 (4), 541-547.
-
(2006)
Mod Pathol.
, vol.19
, Issue.4
, pp. 541-547
-
-
Bode, B.1
Frigerio, S.2
Behnke, S.3
Senn, B.4
Odermatt, B.5
Zimmermann, D.R.6
Moch, H.7
-
10
-
-
70349436013
-
Prognostic significance of epidermal growth factor receptor phosphorylation and mutation in head and neck squamous cell carcinoma
-
Sep
-
Hama, T.; Yuza, Y.; Saito, Y.; Ou, J.; Kondo, S.; Okabe, M.; Yamada, H.; Kato, T.; Moriyama, H.; Kurihara, S.; Urashima, M. Prognostic significance of epidermal growth factor receptor phosphorylation and mutation in head and neck squamous cell carcinoma. Oncologist 2009 Sep, 14 (9), 900-908.
-
(2009)
Oncologist
, vol.14
, Issue.9
, pp. 900-908
-
-
Hama, T.1
Yuza, Y.2
Saito, Y.3
Ou, J.4
Kondo, S.5
Okabe, M.6
Yamada, H.7
Kato, T.8
Moriyama, H.9
Kurihara, S.10
Urashima, M.11
-
11
-
-
0035176636
-
Potential molecular prognostic markers in head and neck squamous cell carcinomas
-
Feb
-
Quon, H.; Liu, F. F.; Cummings, B. J. Potential molecular prognostic markers in head and neck squamous cell carcinomas. Head Neck 2001 Feb, 23 (2), 147-159.
-
(2001)
Head Neck
, vol.23
, Issue.2
, pp. 147-159
-
-
Quon, H.1
Liu, F.F.2
Cummings, B.J.3
-
12
-
-
0037215106
-
Targeting epidermal growth factor receptor in head and neck cancer
-
Jan
-
Ford, A. C.; Grandis, J. R. Targeting epidermal growth factor receptor in head and neck cancer. Head Neck 2003 Jan, 25 (1), 67-73.
-
(2003)
Head Neck
, vol.25
, Issue.1
, pp. 67-73
-
-
Ford, A.C.1
Grandis, J.R.2
-
13
-
-
0033056070
-
A multifactorial approach including tumoural epidermal growth factor receptor, p53, thymidylate synthase and dihydropyrimidine dehydrogenase to predict treatment outcome in head and neck cancer patients receiving 5-fluorouracil
-
Apr
-
Etienne, M. C.; Pivot, X.; Formento, J. L.; Bensadoun, R. J.; Formento, P.; Dassonville, O.; Francoual, M.; Poissonnet, G.; Fontana, X.; Schneider, M.; Demard, F.; Milano, G. A multifactorial approach including tumoural epidermal growth factor receptor, p53, thymidylate synthase and dihydropyrimidine dehydrogenase to predict treatment outcome in head and neck cancer patients receiving 5-fluorouracil. Br J Cancer 1999 Apr, 79 (11-12), 1864-1869.
-
(1999)
Br. J. Cancer
, vol.79
, Issue.11-12
, pp. 1864-1869
-
-
Etienne, M.C.1
Pivot, X.2
Formento, J.L.3
Bensadoun, R.J.4
Formento, P.5
Dassonville, O.6
Francoual, M.7
Poissonnet, G.8
Fontana, X.9
Schneider, M.10
Demard, F.11
Milano, G.12
-
14
-
-
0037674062
-
Phase-II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck
-
May 15
-
Cohen, E. E.; Rosen, F.; Stadler, W. M.; Recant, W.; Stenson, K.; Huo, D.; Vokes, D. E. Phase-II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck. J Clin Oncol 2003 May 15, 21 (10), 1980-1987.
-
(2003)
J. Clin. Oncol.
, vol.21
, Issue.10
, pp. 1980-1987
-
-
Cohen, E.E.1
Rosen, F.2
Stadler, W.M.3
Recant, W.4
Stenson, K.5
Huo, D.6
Vokes, D.E.7
-
15
-
-
1842772526
-
Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck
-
Jan 1
-
Soulieres, D.; Senzer, N. N.; Vokes, E. E.; Hidalgo, M.; Agarwala, S. S.; Siu, L. L. Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck. J Clin Oncol 2004 Jan 1, 22 (1), 77-85.
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.1
, pp. 77-85
-
-
Soulieres, D.1
Senzer, N.N.2
Vokes, E.E.3
Hidalgo, M.4
Agarwala, S.S.5
Siu, L.L.6
-
16
-
-
23844523253
-
Phase II multicenter study of the antiepidermal growth factor receptor monoclonal antibody cetuximab in combination with platinum-based chemotherapy in patients with platinum-refractory metastatic and/or recurrent squamous cell carcinoma of the head and neck
-
Aug. 20
-
Baselga, J.; Trigo, J. M.; Bourhis, J.; Tortochaux, J.; Cortes-Funes, H.; Hitt, R.; Gascon, P.; Amellal, N.; Harstrick, A.; Eckhardt, A. Phase II multicenter study of the antiepidermal growth factor receptor monoclonal antibody cetuximab in combination with platinum-based chemotherapy in patients with platinum-refractory metastatic and/or recurrent squamous cell carcinoma of the head and neck. J Clin Oncol 2005 Aug. 20, 23 (24), 5568-5577.
-
(2005)
J. Clin. Oncol.
, vol.23
, Issue.24
, pp. 5568-5577
-
-
Baselga, J.1
Trigo, J.M.2
Bourhis, J.3
Tortochaux, J.4
Cortes-Funes, H.5
Hitt, R.6
Gascon, P.7
Amellal, N.8
Harstrick, A.9
Eckhardt, A.10
-
17
-
-
32144433159
-
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
-
Feb. 9
-
Bonner, J. A.; Harari, P. M.; Giralt, J.; Azarnia, N.; Shin, D. M.; Cohen, R. B.; Jones, C. U.; Sur, R.; Raben, D.; Jassem, J.; Ove, R.; Kies, M. S.; Baselga, J.; Youssoufian, H.; Amellal, N.; Rowinsky, E. K.; Ang, K. K. Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med 2006 Feb. 9, 354 (6), 567-578.
-
(2006)
N Engl. J. Med.
, vol.354
, Issue.6
, pp. 567-578
-
-
Bonner, J.A.1
Harari, P.M.2
Giralt, J.3
Azarnia, N.4
Shin, D.M.5
Cohen, R.B.6
Jones, C.U.7
Sur, R.8
Raben, D.9
Jassem, J.10
Ove, R.11
Kies, M.S.12
Baselga, J.13
Youssoufian, H.14
Amellal, N.15
Rowinsky, E.K.16
Ang, K.K.17
-
18
-
-
0034954124
-
The type-III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy
-
Jun
-
Pedersen, M. W.; Meltorn, M.; Damstrup, L.; Poulsen, H. S. The type-III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy. Ann Oncol 2001 Jun, 12 (6), 745-760.
-
(2001)
Ann. Oncol.
, vol.12
, Issue.6
, pp. 745-760
-
-
Pedersen, M.W.1
Meltorn, M.2
Damstrup, L.3
Poulsen, H.S.4
-
19
-
-
33646716077
-
Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors
-
May 16
-
Ji, H.; Zhao, X.; Yuza, Y.; Shimamura, T.; Li, D.; Protopopov, A.; Jung, B. L.; McNamara, K.; Xia, H.; Glatt, K. A.; Thomas, R. K.; Sasaki, H.; Horner, J. W.; Eck, M.; Mitchell, A.; Sun, Y.; Al-Hashem, R.; Bronson, R. T.; Rabindran, S. K.; Discafani, C. M.; Maher, E.; Shapiro, G. I.; Meyerson, M.; Wong, K. K. Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors. Proc Natl Acad Sci USA 2006 May 16, 103 (20), 7817-7822.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, Issue.20
, pp. 7817-7822
-
-
Ji, H.1
Zhao, X.2
Yuza, Y.3
Shimamura, T.4
Li, D.5
Protopopov, A.6
Jung, B.L.7
McNamara, K.8
Xia, H.9
Glatt, K.A.10
Thomas, R.K.11
Sasaki, H.12
Horner, J.W.13
Eck, M.14
Mitchell, A.15
Sun, Y.16
Al-Hashem, R.17
Bronson, R.T.18
Rabindran, S.K.19
Discafani, C.M.20
Maher, E.21
Shapiro, G.I.22
Meyerson, M.23
Wong, K.K.24
more..
-
20
-
-
0034163550
-
Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas
-
Mar. 1
-
Frederick, L.; Wang, X. Y.; Eley, G.; James, C. D. Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas. Cancer Res 2000 Mar. 1, 60 (5), 1383-1387.
-
(2000)
Cancer Res.
, vol.60
, Issue.5
, pp. 1383-1387
-
-
Frederick, L.1
Wang, X.Y.2
Eley, G.3
James, C.D.4
-
21
-
-
0034231944
-
Analysis of genomic rearrangements associated with EGRFvIII expression suggests involvement of Alu repeat elements
-
Jul
-
Frederick, L.; Eley, G.; Wang, X. Y.; James, C. D. Analysis of genomic rearrangements associated with EGRFvIII expression suggests involvement of Alu repeat elements. Neuro Oncol 2000 Jul, 2 (3), 159-163.
-
(2000)
Neuro Oncol.
, vol.2
, Issue.3
, pp. 159-163
-
-
Frederick, L.1
Eley, G.2
Wang, X.Y.3
James, C.D.4
-
22
-
-
29144520704
-
Low incidence of mutations in EGFR kinase domain in Caucasian patients with head and neck squamous cell carcinoma
-
Jan
-
Loeffler-Ragg, J.; Witsch-Baumgartner, M.; Tzankov, A.; Hilbe, W.; Schwentner, I.; Sprinzl, G. M.; Utermann, G.; Zwierzina, H. Low incidence of mutations in EGFR kinase domain in Caucasian patients with head and neck squamous cell carcinoma. Eur J Cancer 2006 Jan, 42 (1), 109-111.
-
(2006)
Eur. J. Cancer
, vol.42
, Issue.1
, pp. 109-111
-
-
Loeffler-Ragg, J.1
Witsch-Baumgartner, M.2
Tzankov, A.3
Hilbe, W.4
Schwentner, I.5
Sprinzl, G.M.6
Utermann, G.7
Zwierzina, H.8
-
23
-
-
20244389231
-
Somatic mutations of EGFR gene in squamous cell carcinoma of the head and neck
-
Apr. 15
-
Lee, J. W.; Soung, Y. H.; Kim, S. Y.; Nam, H. K.; Park, W. S.; Nam, S. W.; Kim, M. S.; Sun, D. I.; Lee, Y. S.; Jang, J. J.; Lee, J. Y.; Yoo, N. J.; Lee, S. H. Somatic mutations of EGFR gene in squamous cell carcinoma of the head and neck. Clin Cancer Res 2005 Apr. 15, 11 (8), 2879-2882.
-
(2005)
Clin. Cancer Res.
, vol.11
, Issue.8
, pp. 2879-2882
-
-
Lee, J.W.1
Soung, Y.H.2
Kim, S.Y.3
Nam, H.K.4
Park, W.S.5
Nam, S.W.6
Kim, M.S.7
Sun, D.I.8
Lee, Y.S.9
Jang, J.J.10
Lee, J.Y.11
Yoo, N.J.12
Lee, S.H.13
-
24
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
May 20
-
Lynch, T. J.; Bell, D. W.; Sordella, R.; Gurubhagavatula, S.; Okimoto, R. A.; Brannigan, B. W.; Harris, P. L.; Haserlat, S. M.; Supko, J. G.; Haluska, F. G.; Louis, D. N.; Christiani, D. C.; Settleman, J.; Haber, D. A. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004 May 20, 350 (21), 2129-2139.
-
(2004)
N Engl. J. Med.
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Haserlat, S.M.8
Supko, J.G.9
Haluska, F.G.10
Louis, D.N.11
Christiani, D.C.12
Settleman, J.13
Haber, D.A.14
|