Butyrate and propionate, short chain fatty acids, attenuate myocardial damages by inhibition of apoptosis in a rat model of ischemia-reperfusion

Journal of Applied Biological Chemistry

Volumn 53, Issue 5, 2010, Pages 570-577

  Lim, Sun Ha ^a   Song, Kyung Sik ^b   Lee, Jongwon ^a  

^a Catholic University of Daegu   (South Korea)

^b Kyungpook National University   (South Korea)

Author keywords

Aoptosis; Butyrate; Histone deacetylase inhibitor; Myocardial infarction; Propionate; Short chain fatty acids

Indexed keywords

RATTUS;

EID: 78549264525     PISSN: 19760442     EISSN: None     Source Type: Journal    
DOI: 10.3839/jksabc.2010.088     Document Type: Article

References (37)

1. Abbate A, Bussani R, Amin MS, Vetrovec GW, and Baldi A (2006) Acute myocardial infarction and heart failure: role of apoptosis. Int J Biochem Cell Biol 38, 1834-1840.
2. Adams JM and Cory S (2001) Life-or-death decisions by the Bcl-2 protein family. Trends Biochem Sci 26, 61-66.
3. Breves G and Stuck K (1995) Short-chain fatty acids in the hindgut. In Physiological and Clinical Aspects of Short-Chain Fatty Acids, Cummings JH, Rombeau JL, and Sakata T (eds.), pp. 73-85. Cambridge University Press, Cambridge, UK.
4. Chen YF, Kobayashi S, Chen J, Redetzke RA, Said S, Liang Q, and Gerdes AM (2008) Short term triiodo-L-thyronine treatment inhibits cardiac myocyte apoptosis in border area after myocardial infarction in rats. J Mol Cell Cardiol 44, 180-187.
5. Crow MT, Mani K, Nam YJ, and Kitsis RN (2004) The mitochondrial death pathway and cardiac myocyte apoptosis. Circ Res 95, 957-970.
6. Davie JR (2003) Inhibition of histone deacetylase activity by butyrate. J Nutr 133, 2485S-2493S.
7. Empel VPM, Bertrand ATA, Hofstra L, Crijins HJ, Doevendans PA, and Windt LJ (2005) Myocyte apoptosis in heart failure. Cardiovasc Res 67, 21-29.
8. Granger A, Abdullah I, Heubner F, Stout A, Wang T, Huebner T, Epstein JA, and Gruber PJ (2008) Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice. The FASEB J 22, 3549-3560.
9. Han HS, Choi JS, Kim YJ, Lim SH, Lee HK, Jang JH, Moon YS, and Lee JW (2008) Protective effect of Triticum aestivum L. extract and its component, starch, in rat focal cerebral ischemia. Curr Topics Nutr Res 6, 47-54.
10. Harada M, Qin Y, Takano H, Minamino T, Zou Y, Toko H, Ohtsuka M, Matsuura K, Sano M, Nishi J, Iwanaga K, Akazawa H, Kunieda T, Zhu W, Hasegawa H, Kunisada K, Nagai T, Nakaya H, Yamauchi-Takihara K, and Komuro I (2005) G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes. Nat Med 11, 305-311.
11. Hengartner MO (2000) The biochemistry of apoptosis. Nature 407, 770-776.
12. Kim HJ, Rowe M, Ren M, Hong JS, Chen PS, and Chuang DM (2007) Histone deacetylase inhibitors exhibit antiinflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action. J Pharmacol Exp Ther 321, 892-901.
13. Knudsen KEB, Jensen BB, and Hansen I (1993) Oat bran but not a beta-glucan-enriched oat fraction enhances butyrate production in the large intestine of pigs. J Nutr 123, 1235-1247.
14. Knudsen KEB, Serena A, Canibe N, and Juntunen KS (2003) New insight into butyrate metabolism. Proc Nutr Soc 62, 81-86.
15. Knudsen KEB, Serena A, Kjr AKB, Jørgensen H, and Engberg R (2005) Rye bread enhances the production and plasma concentration of butyrate but not the plasma concentrations of glucose and insulin in pigs. J Nutr 135, 1696-1704.
16. Krijnen PAJ, Nijmeijer R, Meijer CJLM, Visser CA, Hack CE, and Niessen HWM (2002) Apoptosis in myocardial ischemia and infarction. J Clin Pathol 55, 801-811.
17. Lakhani SA, Masud A, Kuida K, Porter Jr. GA, Booth CJ, Mehal WZ, Inayat I, and Flavell RA (2006) Caspases 3 and 7: key mediators of mitochondrial events of apoptosis. Science 311, 847-851.
18. Lee Y and Gustafsson AB (2009) Role of apoptosis in cardiovascular disease. Apoptosis 14, 536-548.
19. Lukas G, Brindle SD, and Green P (1971) The route of absorption of intraperitoneally administered compounds. J Pharmacol Exp Ther 178(3), 562-566.
20. Muir JG, Yeow EGW, Keogh J, Pizzey C, Bird AR, Sharpe K, O'Dea K, and Macrae FA (2004) Combining wheat bran with resistant starch has more beneficial effects on fecal indexes than does wheat bran alone. Am J Clin Nutr 79, 1020-1028.
21. Oltvai ZN, Milliman CL, and Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74, 609-619.
22. Pfeffer MA and Braunwald E (1990) Ventricular remodeling after myocardial infarction. Circulation 81, 1161-1172.
23. Rabkin SW (2009) Apoptosis in human acute myocardial infarction: the rationale for clinical trials of apoptosis inhibition in acute myocardial infarction. Scholarly Research Exchange doi:10.3814/2009/979318.
24. Ren J, Babcock SA, Li QE., Huff AF, Li SY, and Doser TA (2009) Aldehyde dehydrogenase-2 transgene ameliorates chronic alcohol ingestion-induced apoptosis in cerebral cortex. Toxicol Lett 187, 149-156.
25. Saulnier L, Peneau N, and Thibault JF (1995) Variability in grain extract viscosity and water-soluble arabinoxylan content in wheat. J Cereal Sci 22, 259-264.
26. Sengupta N and Seto E (2004) Regulation of histone deacetylase activities. J Cell Biochem 93, 57-67.
27. Shibata R, Sato K, Pimentel DR, Takemura Y, Kihara S, Ohashi K, Funahashi T, Ouchi N, and Walsh K (2005) Adiponectin protects against myocardial ischemiareperfusion injury through AMPK-and COX-2-dependent mechanisms. Nat Med 11(10), 1096-1103.
28. Spierings D, McStay G, Saleh M, Bender C, Chipuk J, Mauer U, and Green DR (2005) Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis. Science 310, 66-67.
29. Sramkova Z, Gregov E, and Sturdik E (2009) Chemical composition and nutritional quality of wheat grain. Acta Chimica Slovaca 2(1), 115-139.
30. Tao L, Gao E, Bryan NS, Qu Y, Liu HR, Hu A, Christopher TA, Lopez BL, Yodoi J, Koch WJ, Feelisch M, and Ma XL (2004) Cardioprotective effects of thioredoxin in myocardial ischemia and reperfusion: role of S-nitrosation. Proc Natl Acad Sci 101(31), 11471-11476.
31. Taylor RC, Cullen SP, and Martin SJ (2008) Apoptosis: controlled demolition at the cellular level. Nat Rev Mol Cell Biol 9, 231-241.
32. Topping DL and Clifton PM (2001) Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. Physiol Rev 81(3), 1031-1064.
33. Waldecker M, Kautenburger T, Daumann H, Bushc C, and Schrenk D (2008) Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon. J Nutr Biochem 19, 587-593.
34. Wong JMW, Souza R, Kendall CWC, Emam A, and Jenkins DJA (2006) Colonic health: fermentation and short chain fatty acids. J Clin Gastroenterol 40(3), 235-243.
35. Yee JC, Leon Gatti M, Philp RJ, Yap M, and Hu WS (2008) Genomic and proteomic exploration of CHO and hybridoma cells under sodium butyrate treatment. Biotechnol Bioeng 99, 1186-1204.
36. Zhao TC, Cheng G, Zhang LX, Tseng YT, and Padbury JF (2007) Inhibition of histone deacetylases triggers pharmacologic preconditioning effects against myocardial ischemic injury. Cardiovasc Res 76, 473-481.
37. Zidar N, Dolenc-Strazar Z, Jeruc J, and Stajer D (2006) Immunohistochemical expression of activated caspase-3 in human myocardial infarction. Virchows Arch 448, 75-79.