Adjuvant chemotherapy versus radiation therapy after radical surgery in high-risk positive node Stage IB/IIA cervical cancer

European Journal of Gynaecological Oncology

Volumn 31, Issue 5, 2010, Pages 545-550

  Mossa, B ^a,c   Mossa, S ^b   Marziani, R ^a,c  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c SAN CAMILLO FORLANINI HOSPITAL   (Italy)

Author keywords

Adjuvant chemotherapy; Cervical cancer; Lymph node metastasis

Indexed keywords

BLEOMYCIN; CISPLATIN; VINBLASTINE;

ADJUVANT CHEMOTHERAPY; ADULT; ARTICLE; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; HIGH RISK PATIENT; HUMAN; INTERMETHOD COMPARISON; LYMPH NODE METASTASIS; LYMPHADENECTOMY; MAJOR CLINICAL STUDY; RADICAL HYSTERECTOMY; TREATMENT OUTCOME; UTERINE CERVIX CANCER;

ADULT; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; CHEMOTHERAPY, ADJUVANT; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYSTERECTOMY; MIDDLE AGED; NEOPLASM STAGING; RADIOTHERAPY, ADJUVANT; SENTINEL LYMPH NODE BIOPSY; UTERINE CERVICAL NEOPLASMS;

EID: 78549257423     PISSN: 03922936     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Peters W.A., Barret R.J., Stock R.J., Monk B.J., Berek J.S., Souhami L. et al.: "Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix". J. Clin. Oncol., 2000, 18, 1606.
2. Landoni F., Maneo A., Colombo A., Placa F., Milani R., Perego P. et al.: "Randomized study of radical surgery versus radiotherapy for Stage IB, IIA cervical cancer". Lancet, 1997, 350, 535.
3. Tinga D.J., Timmer P.R., Bouma J., Aalder J.G.: "Prognostic significance of single versus multiple lymph node metastases in cervical carcinoma Stage IB". Gynecol. Oncol., 1990, 39, 175.
4. Liu M.T., Hsu J.C., Liu W.S., Wang A.Y. Ghang T.H., Pi C.P. et al.: "Prognostic factors affecting the outcomes of early cervical cancer treated with radical hysterectomy and post operative adjuvant therapy". Eur. J. Cancer Care, 2008, 17, 174.
5. Hsu C.T., Cheng Y.S., Su S.C.: "Prognosis of uterine cervical cancer with extensive lymph node metastasis. Special emphasis on the value of pelvic lymphadenectomy in the surgical treatment of uterine cervical carcinoma". Am. J. Obstet. Gynecol., 1972, 114, 954.
6. Pilleron J., Durand J., Hamelin J.: "Prognostic value of node metastasis in cancer of the uterine cervix". Am. J. Obstet. Gynecol, 1974, 119, 458.
7. Inoue T., Morita K.: "The prognostic significance of number of positive nodes in cervical carcinoma Stages IB, IIA, and IIB". Cancer, 1990, 65, 1923.
8. Yuan C., Wang P., Lai C., Tsu E., Yen M., Ng H.: "Recurrence and survival analysis of 1,115 cervical cancer patients treated with radical hysterectomy". Gynecol. Obstet. Invest., 1999, 47, 127.
9. Nakanishi T., Ishikawa H., Suzuki Y., Inoue T., Nakamura S., Kuzuya K.: "A comparison of prognosis of pathologic stage IB adenocarcinoma and squamous cell carcinoma of the uterine cervix". Gynecol. Oncol., 2000, 79, 289.
10. Atlan D., Touboul E., Deniaud-Alexandre E., Lefranc J.P., Antoine J.M., Jannet D. et al.: "Operable Stages IB and II cervical carcinomas: a retrospective study comparing preoperative uterovaginal brachitherapy and postoperative radiotherapy". Int. J. Rad. Oncol. Biol. Phys., 2002, 54, 780.
11. Piver M.S., Chung W.S.: "Prognostic significance of cervical lesion size and pelvic node metastasis in cervical carcinoma". Obstet. Gynecol., 1975, 46, 507.
12. Sedlis A., Bundy B.N., Rotman M.Z., Lentz S.S., Muderspach L.I., Zaino R.J.: "A randomized trial of pelvic radiation therapy versus no further therapy in selected patients with stage IB carcinoma of the cervix after radical hysterectomy and pelvic lymphadenectomy. A Gynecologic Oncology Group Study". Gynecol. Oncol., 1999, 73, 177.
13. Aoki Y., Sasaki M., Watanabe M., Sato T., Tsuncki L.I., Aida H., Tanaka K.: "High-risk group in node-positive patients with Stage IB, IIA, and IIB cervical carcinoma after radical hysterectomy and postoperative pelvic irradiation". Gynecol. Oncol., 2000, 77, 305.
14. Monk B.J., Cha D.S., Walker J.L., Burger R.A., Ramsinghani N.S., Manetta A. et al.: "Extend of disease as an indication for pelvic radiation following radical hysterectomy and bilateral pelvic lymph node dissection in the treatment of Stage IB and IIA cervical carcinoma". Gynecol. Oncol., 1994, 54, 4.
15. Lahousen M., Haas J., Pickel H., Hackl A., Kurz C., Ogris H.: "Chemotherapy versus radiotherapy versus observation for high-risk cervical carcinoma after radical hysterectomy: a randomized, prospective, multicenter trial". Gynecol. Oncol., 1999, 73, 196.
16. Lin H., ChangChien C.C., Huang E.Y., Eng H.L., Huang C.C.: "The role of radical surgery followed by adjuvant therapy for high-risk early-stage cervical carcinoma patients with pelvic lymph node metastasis". Eur. J. Obstet. Gynecol. Reprod. Biol., 2000, 93, 85.
17. Lin H., ChangChien C.C., Chang S.Y., Leung S.W.: "Survival advantages and complications of adjuvant therapy in early-stage cervical cancer with pelvic node metastasis". Chang Gung Med., 1998, 21, 383.
18. Martinbeau P., Kjorstad K., Iversen T.: "Stage Ib of the cervix: the Norwegian Radium Hospital. Results when pelvic nodes are involved". Obstet. Gynecol, 1982, 60, 215.
19. Morton G.C., Thomas G.M.: "Does adjuvant chemotherapy change the prognosis of cervical cancer?". Curr. Opin. Obstet. Gynecol., 1996, 8, 17.
20. Ng H.T., Yuan C.C., Kan Y.Y., Ho E.S.C., Yen M.S., Chao K.C.: "An evaluation of chemotherapy in patients with cancer of the cervix and lymph node metastases". Arch. Gynecol. Obstet., 1995, 256, 1.
21. Park R.C., Thigpen J.T.: "Chemotherapy in advanced and recurrent cervical cancer. A Review". Cancer (suppl.), 1993, 71, 1446.
22. Morrow P.C.: "Panel report. Is pelvic radiation beneficial in the postoperative management of Stage IB squamous cell carcinoma of the cervix with pelvic node metastasis treated by radical hysterectomy and pelvic lymphadenectomy?". Gynecol. Oncol., 1980, 10, 105.
23. Kinney W.K., Alvarez R.D., Reid G.C., Schray M.F., Soong S.J., Moreley G.W.: "Value of adjuvant whole-pelvis irradiation after Wertheim hysterectomy for early stage squamous carcinoma of the cervix with pelvic nodal metastasis: a matched-control study". Gynecol. Oncol., 1989, 34, 258.
24. Inoue T., Morita K.: "Five-years results of postoperative extended field irradiation on 76 patients with nodal metastases from cervical carcinoma Stages IB to IIIB". Cancer, 1988, 61, 2009.
25. Tanaka Y., Sawada S., Murata T.: "Relationship between lymph node metastases and prognosis in patients irradiated postoperatively for carcinoma of the uterine cervix". Acta Radiol. Oncol., 1984, 23, 455.
26. Sivanesaratnam V., Jayalakshmi P.: "Mitomycin C adjuvant chemotherapy after Wertheim's hysterectomy for Stage Ib cervical cancer". Cancer, 1989, 64, 798.
27. Lai C.H., Lin T.S., Soong Y.K., Chen S.F.: "Adjuvant chemotherapy after radical hysterectomy for cervical carcinoma". Gynecol. Oncol., 1989, 35, 193.
28. Fuller A.F., Elliott N., Kosloff C., Lewis J.L.: "Lymph node metastases from carcinoma of the cervix, Stage IB and IIA: implications for prognosis and treatment". Gynecol. Oncol., 1982, 13, 165.
29. Tattersall M.H.N., Ramirez C., Coppleson M.: "A randomized trial of adjuvant chemotherapy after radical hysterectomy in Stage IB-IIA cervical cancer patients with pelvic lymph node metastases". Gynecol. Oncol., 1992, 46, 176.
30. Valle G., Napolitano C.: "Linfadenectomia lombo-pelvica e linfadenectomia convenzionale: confronto delle sopravvivenze in due serie contemporanee di cervicocarcinomi trattati con Wertheim o eviscerazione". Atti del 54° Congresso Nazionale della Società Italiana di Ostetricia e Ginecologia Milano, 16-19 Sett., 1970.
31. Piver M.S., Rutledge F., Smith J.P.: "Five classes of extended hysterectomy for women with cervical cancer". Obstet. Gynecol., 1974, 44, 265.
32. Hoskins W.J., Ford J.H., Lutz M.H., Averette H.E.: "Radical hysterectomy and pelvic lymphadenectomy for the management of early invasive cervical cancer". Gynecol. Oncol., 1976, 4, 278.
33. Artman L.E., Hoskins W.J., Bibro M.C.: "Radical hysterectomy and pelvic lymphadenectomy for Stage IB carcinoma of the cervix". Gynecol. Oncol., 1987, 25, 8.
34. Napolitano C.: "Management of invasive cervical carcinoma: our experience from 1961 to 1979". New trends in Gynecology and Obstetrics, 1986, 2.
35. Havrilesky L.J., Leath C.A., Huh W., Calingaert B., Bentley R.C., Soper J.T., Alvarez S.A.: "Radical hysterectomy and pelvic lymphadenectomy for Stage IB2 cervical cancer". Gynecol. Oncol., 2004, 93, 420.
36. Mossa B., Pramarino M.L., Napolitano C., Marziani R., Imperato F., Marzetti L.: "Does adjuvant chemotherapy improve the prognosis of cervical carcinoma with lymph-node metastasis? A long term follow-up". Eur. J. Gynaecol. Oncol., 2003, 24, 33.
37. Nadereh B., Mojgan K.Z., Maryam D.: "Adjuvant therapy influence in early stage cervical cancer patients in Iran". Asian Pacific J. Cancer Prev., 2009, 10, 613.
38. Kinney W.K., Alvarez R.D., Reid G.C., Schray M.F., Soong S.J., Morley G.W.: "Value of adjuvant whole-pelvis irradiation after Wertheim hysterectomy for early stage squamous carcinoma of the cervix with pelvic nodal metastasis: a matched-control study". Gynecol. Oncol., 1989, 34, 258.
39. Levi J.A., Wheeler H.R., Friedlander M., Tattersall M.H.N., Kefford R., Dalley D.: "Dual sequential non-cross resistant chemotherapy for advanced stage squamous cell carcinoma of the cervix". Gynecol. Oncol., 1992, 45, 329.
40. Ho C.M., Chien T.Y., Hung S.H.: "Multivariate analysis of the prognostic factors and outcomes in early cervical cancers patients undergoing radical hysterectomy". Gynecol. Oncol., 2004, 93, 458.
41. Sardi J.E., di Paola G.R., Cachau A., Ortiz O.C., Sananes C., Giaroli A. et al.: "A possibile new trend in the management of the carcinoma of the cervix uteri". Gynecol. Oncol., 1986, 25, 139.
42. Lai C.H., Hong J.H., Hsueh S., Ng K.K., Chang T.C., Tseng C.J. et al.: "Preoperative prognostic variables and the impact of post-operative adjuvant therapy on the outcomes of Stage IB or II cervical carcinoma patients with or without pelvic lymph node metastases. An analysis of 891 cases". Cancer, 1999, 85, 1537.
43. Weiss G.R., Green S., Hannigan E.V., Boutselis J.G., Surwit E.A., Albert D.S.: "A phase III trial of cisplatin and 5-fluorouracil with allopurinol for recurrent or metastatic carcinoma of the uterine cervix: a southwest ocology group trial". Gynecol. Oncol., 1990, 37, 354.
44. Omura G.A.: "Chemotherapy for Stage IVB or recurrent cancer of the uterine cervix". J. Nat. Cancer Instit., 1996, 21, 123.
45. Mainero C., Napolitano C., Crosara B.: "Gli errori di classificazione del carcinoma della portio". Aggiornamenti in ostetricia e ginecologia, 1972, 5, 200.
46. Kenter G.G., Hellebrekers B.W.J., Zwinderman K.H., Van der Vijver M., Peters L.A.W., Trimbos J.B: "The case for completing the lymphadenectomy when positive lymph nodes are found during radical hysterectomy for cervical carcinoma". Acta Obstet. Gynecol. Scand., 2000, 79, 72.
47. Samlal R.A.K., Van der Velden J.: "Early cervical carcinoma: How to manage high-risk patients after radical hysterectomy". Eur. J. Obstet. Gynecol. Reprod. Biol., 1999, 85, 137.