-
2
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A, Siegel R, Ward E, Hao Y, Thun MJ. Cancer statistics, 2009. Cancer J Clin 2009;59:225-49.
-
(2009)
Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Thun, M.J.5
-
3
-
-
67650741782
-
Management of breast cancer in the genome era
-
Morrow PK, Hortobagyi GN. Management of breast cancer in the genome era. Annu Rev Med 2009;60:153-65.
-
(2009)
Annu Rev Med
, vol.60
, pp. 153-165
-
-
Morrow, P.K.1
Hortobagyi, G.N.2
-
5
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S, et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001;344:783-92.
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
6
-
-
0037429725
-
The ErbB receptors and their role in cancer progression
-
Holbro T, Civenni G, Hynes NE. The ErbB receptors and their role in cancer progression. Exp Cell Res 2003;284:99-110.
-
(2003)
Exp Cell Res
, vol.284
, pp. 99-110
-
-
Holbro, T.1
Civenni, G.2
Hynes, N.E.3
-
7
-
-
18344390418
-
ERBB receptors and cancer: The complexity of target inhibitors
-
Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of target inhibitors. Nat Rev Cancer 2005;5:341-54.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 341-354
-
-
Hynes, N.E.1
Lane, H.A.2
-
8
-
-
0022588467
-
Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor
-
Yamamoto T, Ikawa S, Akiyama T, et al. Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor. Nature 1986;319:230-4.
-
(1986)
Nature
, vol.319
, pp. 230-234
-
-
Yamamoto, T.1
Ikawa, S.2
Akiyama, T.3
-
9
-
-
0242468905
-
Dysregulation of cellular signaling by HER2/neu in breast cancer
-
Zhou BP, Hung MC. Dysregulation of cellular signaling by HER2/neu in breast cancer. Semin Oncol 2003;30:38-48.
-
(2003)
Semin Oncol
, vol.30
, pp. 38-48
-
-
Zhou, B.P.1
Hung, M.C.2
-
10
-
-
0037429779
-
The deaf and dumb: The biology of ErbB-2 and ErbB-3
-
Citri A, Skaria KB, Yarden Y. The deaf and dumb: the biology of ErbB-2 and ErbB-3. Exp Cell Res 2003;284:54-65.
-
(2003)
Exp Cell Res
, vol.284
, pp. 54-65
-
-
Citri, A.1
Skaria, K.B.2
Yarden, Y.3
-
11
-
-
38849199203
-
Shared principles in NF-κB signaling
-
Hayden MS, Ghosh S. Shared principles in NF-κB signaling. Cell 2008;132:344-62.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
12
-
-
65649107679
-
Nuclear factor-κB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo
-
Liu M, Ju X, Willmarth NE, et al. Nuclear factor-κB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo. Am J Pathol 2009;174:1910-20.
-
(2009)
Am J Pathol
, vol.174
, pp. 1910-1920
-
-
Liu, M.1
Ju, X.2
Willmarth, N.E.3
-
13
-
-
68149164966
-
The canonical NF-κB pathway is required for formation of luminal mammary neoplasias and is activated in the mammary progenitor population
-
Pratt MA, Tobbo E, Robertson SJ, et al. The canonical NF-κB pathway is required for formation of luminal mammary neoplasias and is activated in the mammary progenitor population. Oncogene 2009;28: 2710-22.
-
(2009)
Oncogene
, vol.28
, pp. 2710-2722
-
-
Pratt, M.A.1
Tobbo, E.2
Robertson, S.J.3
-
14
-
-
33644877161
-
Crossroads of estrogen receptor and NF-κB signaling
-
Biswas DK, Singh S, Shi Q, Pardee AB, Iglehart JD. Crossroads of estrogen receptor and NF-κB signaling. Sci STKE 2005;2005:e27.
-
(2005)
Sci STKE
, vol.2005
-
-
Biswas, D.K.1
Singh, S.2
Shi, Q.3
Pardee, A.B.4
Iglehart, J.D.5
-
15
-
-
0029851287
-
Interaction of D-type cyclins with a novel myb-like transcription factor, DMP1
-
Hirai H, Sherr CJ. Interaction of D-type cyclins with a novel myb-like transcription factor, DMP1. Mol Cell Biol 1996;16:6457-67.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6457-6467
-
-
Hirai, H.1
Sherr, C.J.2
-
16
-
-
0031937638
-
Gene expression and cell cycle arrest mediated by transcription factor DMP1 is antagonized by D-type cyclins through a cyclin-dependent-kinase- independent mechanism
-
Inoue K, Sherr CJ. Gene expression and cell cycle arrest mediated by transcription factor DMP1 is antagonized by D-type cyclins through a cyclin-dependent-kinase-independent mechanism. Mol Cell Biol 1998;18:1590-600.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 1590-1600
-
-
Inoue, K.1
Sherr, C.J.2
-
17
-
-
0033616608
-
Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1
-
Inoue K, Roussel MF, Sherr CJ. Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1. Proc Natl Acad Sci U S A 1999;96:3993-8.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3993-3998
-
-
Inoue, K.1
Roussel, M.F.2
Sherr, C.J.3
-
19
-
-
33747819484
-
Divorcing ARF and p53: An unsettled case
-
Sherr CJ. Divorcing ARF and p53: an unsettled case. Nat Rev Cancer 2006;6:663-73.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 663-673
-
-
Sherr, C.J.1
-
20
-
-
0034661167
-
Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis
-
Inoue K, Wen R, Rehg JE, et al. Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis. Genes Dev 2000;14:1797-809.
-
(2000)
Genes Dev
, vol.14
, pp. 1797-1809
-
-
Inoue, K.1
Wen, R.2
Rehg, J.E.3
-
21
-
-
0035890273
-
Dmp1 is haplo-insufficient for tumor suppression and modifies the frequencies of Arf and p53 mutations in Myc-induced lymphomas
-
Inoue K, Zindy F, Randle DH, Rehg JE, Sherr CJ. Dmp1 is haplo-insufficient for tumor suppression and modifies the frequencies of Arf and p53 mutations in Myc-induced lymphomas. Genes Dev 2001;15:2934-9.
-
(2001)
Genes Dev
, vol.15
, pp. 2934-2939
-
-
Inoue, K.1
Zindy, F.2
Randle, D.H.3
Rehg, J.E.4
Sherr, C.J.5
-
22
-
-
11144256284
-
Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor
-
Sreeramaneni R, Chaudhry A, McMahon M, Sherr CJ, Inoue K. Ras-Raf-Arf signaling critically depends on the Dmp1 transcription factor. Mol Cell Biol 2005;25:220-32.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 220-232
-
-
Sreeramaneni, R.1
Chaudhry, A.2
McMahon, M.3
Sherr, C.J.4
Inoue, K.5
-
23
-
-
33845709782
-
Expression of Dmp1 in specific differentiated, nonproliferating cells and its repression by E2Fs
-
Mallakin A, Taneja P, Matise LA, Willingham MC, Inoue K. Expression of Dmp1 in specific differentiated, nonproliferating cells and its repression by E2Fs. Oncogene 2006;25:7703-13.
-
(2006)
Oncogene
, vol.25
, pp. 7703-7713
-
-
Mallakin, A.1
Taneja, P.2
Matise, L.A.3
Willingham, M.C.4
Inoue, K.5
-
24
-
-
35148866681
-
Repression of Dmp1 and Arf transcription by anthracyclins: Critical roles of the NF-κB subunit p65
-
Taneja P, Mallakin A, Matise LA, Frazier DP, Choudhary M, Inoue K. Repression of Dmp1 and Arf transcription by anthracyclins: critical roles of the NF-κB subunit p65. Oncogene 2007;26:7457-66.
-
(2007)
Oncogene
, vol.26
, pp. 7457-7466
-
-
Taneja, P.1
Mallakin, A.2
Matise, L.A.3
Frazier, D.P.4
Choudhary, M.5
Inoue, K.6
-
26
-
-
35148886223
-
Mutually exclusive inactivation of DMP1 and ARF/p53 in lung cancer
-
Mallakin A, Sugiyama T, Taneja P, et al. Mutually exclusive inactivation of DMP1 and ARF/p53 in lung cancer. Cancer Cell 2007;12: 381-94.
-
(2007)
Cancer Cell
, vol.12
, pp. 381-394
-
-
Mallakin, A.1
Sugiyama, T.2
Taneja, P.3
-
27
-
-
49649092472
-
Emerging roles of DMP1 in lung cancer
-
Inoue K, Sugiyama T, Taneja P, Morgan RL, Frazier DP. Emerging roles of DMP1 in lung cancer. Cancer Res 2008;68:4487-90.
-
(2008)
Cancer Res
, vol.68
, pp. 4487-4490
-
-
Inoue, K.1
Sugiyama, T.2
Taneja, P.3
Morgan, R.L.4
Frazier, D.P.5
-
28
-
-
47049103853
-
Role of DMP1 and its future in lung cancer diagnostics
-
Sugiyama T, Frazier DP, Taneja P, Morgan RL, Willingham MC, Inoue K. Role of DMP1 and its future in lung cancer diagnostics. Expert Rev Mol Diagn 2008;8:435-47.
-
(2008)
Expert Rev Mol Diagn
, vol.8
, pp. 435-447
-
-
Sugiyama, T.1
Frazier, D.P.2
Taneja, P.3
Morgan, R.L.4
Willingham, M.C.5
Inoue, K.6
-
29
-
-
0033580429
-
Cloning and chromosomal localization of the gene encoding human cyclin D-binding Myb-like protein (hDMP1)
-
Bodner SM, Naeve CW, Rakestraw KM, et al. Cloning and chromosomal localization of the gene encoding human cyclin D-binding Myb-like protein (hDMP1). Gene 1999;229:223-8.
-
(1999)
Gene
, vol.229
, pp. 223-228
-
-
Bodner, S.M.1
Naeve, C.W.2
Rakestraw, K.M.3
-
30
-
-
0242384942
-
Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns
-
Tschan MP, Fisher KM, Fung VS, et al. Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns. J Biol Chem 2003;278:42750-60.
-
(2003)
J Biol Chem
, vol.278
, pp. 42750-42760
-
-
Tschan, M.P.1
Fisher, K.M.2
Fung, V.S.3
-
31
-
-
84920218738
-
Loss of heterozygosity on chromosome 7q and aggressive primary breast cancer
-
BiecheI,ChampemeMH,MatifasF,HaceneK,CallahanR,LindereauR. Loss of heterozygosity on chromosome 7q and aggressive primary breast cancer. Lancet 1992;339:139-43.
-
(1992)
Lancet
, vol.339
, pp. 139-143
-
-
Bieche, I.1
Champeme, M.H.2
Matifas, F.3
Hacene, K.4
Callahan, R.5
Lindereau, R.6
-
32
-
-
0031048452
-
Loss of heterozygosity at chromosome 7q in human breast cancer: Association with clinical variables
-
Kristjansson AK, Eiriksdottir G, Ragnarsson G, et al. Loss of heterozygosity at chromosome 7q in human breast cancer: association with clinical variables. Anticancer Res 1997;17:93-8.
-
(1997)
Anticancer Res
, vol.17
, pp. 93-98
-
-
Kristjansson, A.K.1
Eiriksdottir, G.2
Ragnarsson, G.3
-
33
-
-
0035853729
-
Role of p53 in HER2-induced proliferation or apoptosis
-
Casalini P, Botta L, Menard S. Role of p53 in HER2-induced proliferation or apoptosis. J Biol Chem 2001;276:12449-53.
-
(2001)
J Biol Chem
, vol.276
, pp. 12449-12453
-
-
Casalini, P.1
Botta, L.2
Menard, S.3
-
34
-
-
0023713558
-
Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene
-
Muller WJ, Sinn E, Pattengale PK, Wallace R, Leder P. Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell 1988;54:105-15.
-
(1988)
Cell
, vol.54
, pp. 105-115
-
-
Muller, W.J.1
Sinn, E.2
Pattengale, P.K.3
Wallace, R.4
Leder, P.5
-
35
-
-
59449093003
-
The possible involvement of virus in breast cancer
-
Amarante MK, Watanabe MA. The possible involvement of virus in breast cancer. J Cancer Res Clin Oncol 2009;135:329-37.
-
(2009)
J Cancer Res Clin Oncol
, vol.135
, pp. 329-337
-
-
Amarante, M.K.1
Watanabe, M.A.2
-
36
-
-
0028835250
-
Detection of mammary tumor virus env gene-like sequences in human breast cancer
-
Wang Y, Holland JF, Bleiweiss IJ, et al. Detection of mammary tumor virus env gene-like sequences in human breast cancer. Cancer Res 1995;55:5173-9.
-
(1995)
Cancer Res
, vol.55
, pp. 5173-5179
-
-
Wang, Y.1
Holland, J.F.2
Bleiweiss, I.J.3
-
37
-
-
74949144054
-
The Arf-inducing transcription factor Dmp1 encodes transcriptional activator of amphiregulin, thrombospondin-1, JunB and Egr1
-
Mallakin A, Sugiyama T, Kai F, et al. The Arf-inducing transcription factor Dmp1 encodes transcriptional activator of amphiregulin, thrombospondin-1, JunB and Egr1. Int J Cancer 2010;126: 1403-16.
-
(2010)
Int J Cancer
, vol.126
, pp. 1403-1416
-
-
Mallakin, A.1
Sugiyama, T.2
Kai, F.3
-
38
-
-
0038520079
-
Hormonal and dietary modulation of mammary carcinogenesis in mouse mammary tumor virus-c-erbB-2 transgenic mice
-
Yang X, Edgerton SM, Kosanke SD, et al. Hormonal and dietary modulation of mammary carcinogenesis in mouse mammary tumor virus-c-erbB-2 transgenic mice. Cancer Res 2003;63:2425-33.
-
(2003)
Cancer Res
, vol.63
, pp. 2425-2433
-
-
Yang, X.1
Edgerton, S.M.2
Kosanke, S.D.3
-
39
-
-
11144348206
-
Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu-overexpressing breast cancer cells
-
Faltus T, Yuan J, Zimmer B, et al. Silencing of the HER2/neu gene by siRNA inhibits proliferation and induces apoptosis in HER2/neu-overexpressing breast cancer cells. Neoplasia 2004;6: 786-95.
-
(2004)
Neoplasia
, vol.6
, pp. 786-795
-
-
Faltus, T.1
Yuan, J.2
Zimmer, B.3
-
40
-
-
33750457370
-
Post-translational modifications regulating the activity and function of the nuclear factor κ B pathway
-
Review
-
Perkins ND. Post-translational modifications regulating the activity and function of the nuclear factor κ B pathway. Oncogene 2006; 25:6717-30, Review.
-
(2006)
Oncogene
, vol.25
, pp. 6717-6730
-
-
Perkins, N.D.1
-
41
-
-
1842526076
-
Active repression of antiapoptotic gene expression by RelA(p65) NF-κ B
-
Campbell KJ, Rocha S, Perkins ND. Active repression of antiapoptotic gene expression by RelA(p65) NF-κ B. Mol Cell 2004;13:853-65.
-
(2004)
Mol Cell
, vol.13
, pp. 853-865
-
-
Campbell, K.J.1
Rocha, S.2
Perkins, N.D.3
-
42
-
-
17144422434
-
Regulation of NF-κB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor
-
Rocha S, Garrett MD, Campbell KJ, Schumm K, Perkins ND. Regulation of NF-κB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor. EMBO J 2005;24:1157-69.
-
(2005)
EMBO J
, vol.24
, pp. 1157-1169
-
-
Rocha, S.1
Garrett, M.D.2
Campbell, K.J.3
Schumm, K.4
Perkins, N.D.5
-
43
-
-
4844231449
-
Tumor suppressor ARF inhibits HER-2/neu-mediated oncogenic growth
-
Zhang Y, Yang HY, Zhang XC, Yang H, Tsai M, Lee MH. Tumor suppressor ARF inhibits HER-2/neu-mediated oncogenic growth. Oncogene 2004;23:7132-43.
-
(2004)
Oncogene
, vol.23
, pp. 7132-7143
-
-
Zhang, Y.1
Yang, H.Y.2
Zhang, X.C.3
Yang, H.4
Tsai, M.5
Lee, M.H.6
-
44
-
-
33846214693
-
Regulation of the Arf tumor suppressor in Emicro-Myc transgenic mice: Longitudinal study of Myc-induced lymphomagenesis
-
Bertwistle D, Sherr CJ. Regulation of the Arf tumor suppressor in Emicro-Myc transgenic mice: longitudinal study of Myc-induced lymphomagenesis. Blood 2007;109:792-4.
-
(2007)
Blood
, vol.109
, pp. 792-794
-
-
Bertwistle, D.1
Sherr, C.J.2
-
46
-
-
38949083839
-
Ectopic Tbx2 expression results in polyploidy and cisplatin resistance
-
Davis E, Teng H, Bilican B, et al. Ectopic Tbx2 expression results in polyploidy and cisplatin resistance. Oncogene 2008;27:976-84.
-
(2008)
Oncogene
, vol.27
, pp. 976-984
-
-
Davis, E.1
Teng, H.2
Bilican, B.3
-
47
-
-
33750848203
-
Regulation of the p14ARF-Mdm2-53 pathway: An overview in breast cancer
-
Agrawal A, Yang J, Murphy RF, Agrawal DK. Regulation of the p14ARF-Mdm2-53 pathway: an overview in breast cancer. Exp Mol Pathol 2006;81:115-22.
-
(2006)
Exp Mol Pathol
, vol.81
, pp. 115-122
-
-
Agrawal, A.1
Yang, J.2
Murphy, R.F.3
Agrawal, D.K.4
-
48
-
-
0035931859
-
Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
-
Ohtani N, Zebedee Z, Huot TJ, et al. Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence. Nature 2001;409:1067-70.
-
(2001)
Nature
, vol.409
, pp. 1067-1070
-
-
Ohtani, N.1
Zebedee, Z.2
Huot, T.J.3
|