CH05-10, a novel indinavir analog, is a broad-spectrum antitumor agent that induces cell cycle arrest, apoptosis, endoplasmic reticulum stress and autophagy

Cancer Science

Volumn 101, Issue 12, 2010, Pages 2644-2651

  You, Jianlan ^a   He, Zhengxiang ^a   Chen, Lili ^a   Deng, Gang ^b   Liu, Wei ^b   Qin, Li ^a   Qiu, Fayang ^b   Chen, Xiaoping ^a  

^a State Key Laboratory of Respiratory Disease   (China)

^b GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE; CH 05 0; CH 05 10; INDINAVIR; NELFINAVIR; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL STRAIN K 562; CELL STRAIN MCF 7; CENTRAL NERVOUS SYSTEM TUMOR; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; ENDOPLASMIC RETICULUM STRESS; HELA CELL; HUMAN; HUMAN CELL; IC 50; KIDNEY CANCER; LEUKEMIA CELL; LUNG CANCER; MELANOMA CELL; PRIORITY JOURNAL; PROSTATE CANCER;

ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; ENDOPLASMIC RETICULUM; HUMANS; INDINAVIR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 78449304135     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2010.01724.x     Document Type: Article

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