Critical role for hyperpolarization-activated cyclic nucleotide-gated channel 2 in the AIF-mediated apoptosis

EMBO Journal

Volumn 29, Issue 22, 2010, Pages 3869-3878

  Norberg, Erik ^a   Karlsson, Marie ^a   Korenovska, Olga ^a   Szydlowski, Susanne ^a   Silberberg, Gilad ^a   Uhlén, Per ^a   Orrenius, Sten ^a   Zhivotovsky, Boris ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

apoptosis; apoptosis inducing factor; calcium signalling; calpain; HCN channel

Indexed keywords

APOPTOSIS INDUCING FACTOR; CYCLIC NUCLEOTIDE GATED CHANNEL; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL 2; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONTROLLED STUDY; DOWN REGULATION; LUNG CARCINOMA; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; SITE DIRECTED MUTAGENESIS;

ANIMALS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; CALCIUM; CALPAIN; CASPASES; CELL LINE; CELL LINE, TUMOR; CELLS, CULTURED; ENZYME INHIBITORS; GENE EXPRESSION; HEK293 CELLS; HUMANS; ION CHANNELS; NEURONS; PHOSPHORYLATION; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; STAUROSPORINE;

EID: 78449291827     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2010.253     Document Type: Article

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