High-content screening for compounds that affect mtDNA-encoded protein levels in eukaryotic cells

Journal of Biomolecular Screening

Volumn 15, Issue 8, 2010, Pages 937-948

  Nadanaciva, Sashi ^a   Dillman, Keith ^a   Gebhard, David F ^a   Shrikhande, Alka ^a   Will, Yvonne ^a  

^a PFIZER INC   (United States)

Author keywords

antibiotic; antiretroviral; high content screening; mitochondrial; ribosome

Indexed keywords

ABACAVIR; AMIKACIN; AMOXICILLIN; AZITHROMYCIN; AZTREONAM; CEFTAZIDIME; CHLORAMPHENICOL; CIPROFLOXACIN; CLINDAMYCIN; CYTOCHROME C OXIDASE; DOXYCYCLINE; ERYTHROMYCIN; GENTAMICIN; IMIPENEM; JOSAMYCIN; KANAMYCIN; LAMIVUDINE; LEVOFLOXACIN; LINEZOLID; MARBOFLOXACIN; MINOCYCLINE; NEOMYCIN; NETILMICIN; NORFLOXACIN; OFLOXACIN; POLYMYXIN B; TELITHROMYCIN; TETRACYCLINE; TOBRAMYCIN; TROVAFLOXACIN;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; EPITHELIUM CELL; EUKARYOTIC CELL; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RIBOSOME; SCREENING;

ANTI-BACTERIAL AGENTS; ANTI-RETROVIRAL AGENTS; CELL LINE, TRANSFORMED; DNA, MITOCHONDRIAL; EFFICIENCY; ELECTRON TRANSPORT COMPLEX IV; EPITHELIAL CELLS; EUKARYOTIC CELLS; FLUOROQUINOLONES; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; JOSAMYCIN; LIVER; MITOCHONDRIAL PROTEINS; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; OXIDATIVE PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITORS;

EUKARYOTA;

EID: 78449283897     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057110373547     Document Type: Article

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