Developing tools for risk assessment in protected species: Relative potencies inferred from competitive binding of halogenated aromatic hydrocarbons to aryl hydrocarbon receptors from beluga (Delphinapterus leucas) and mouse

Aquatic Toxicology

Volumn 100, Issue 3, 2010, Pages 238-245

  Jensen, Brenda A ^a,b   Reddy, Christopher M ^a   Nelson, Robert K ^a   Hahn, Mark E ^a  

^a WOODS HOLE OCEANOGRAPHIC INSTITUTION   (United States)

^b HAWAII PACIFIC UNIVERSITY   (United States)

Author keywords

AHR; Beluga; Cetacean; Dioxin; PCB; Relative potencies; Risk assessment; Species specific; Structure activity relationships; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; COMPLEMENTARY DNA; HALOGENATED AROMATIC HYDROCARBON DERIVATIVE; ORGANIC COMPOUND; POLYCHLORINATED BIPHENYL; POLYCHLORINATED BIPHENYL 105; POLYCHLORINATED BIPHENYL 118; POLYCHLORINATED BIPHENYL 126; POLYCHLORINATED BIPHENYL 128; POLYCHLORINATED BIPHENYL 156; POLYCHLORINATED BIPHENYL 169; POLYCHLORINATED BIPHENYL 77; POLYCHLORINATED BIPHENYL 81; POLYCHLORINATED BIPHENYL DERIVATIVE; UNCLASSIFIED DRUG;

BIOACCUMULATION; BIOCHEMISTRY; CETACEAN; ECOTOXICOLOGY; PAH; PCB; POLLUTION EFFECT; RISK ASSESSMENT; RODENT; TCDD;

ANALYTIC METHOD; ARTICLE; BELUGA WHALE; BINDING AFFINITY; CETACEA; CHEMICAL STRUCTURE; CONTROLLED STUDY; IC 50; MOLECULAR CLONING; MOUSE STRAIN; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; RISK ASSESSMENT; TOXIN ANALYSIS; WORLD HEALTH ORGANIZATION;

ANIMALS; BELUGA WHALE; BENZOFURANS; BINDING, COMPETITIVE; ENDANGERED SPECIES; ENVIRONMENTAL POLLUTANTS; HYDROCARBONS, AROMATIC; MICE; POLYCHLORINATED BIPHENYLS; RECEPTORS, ARYL HYDROCARBON; RISK ASSESSMENT; TETRACHLORODIBENZODIOXIN;

CETACEA; DELPHINAPTERUS LEUCAS; MAMMALIA; ODONTOCETI; RODENTIA;

EID: 78449268048     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2010.07.021     Document Type: Article

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