PLGA based drug delivery systems (DDS) for the sustained release of insulin: Insight into the protein/polyester interactions and the insulin release behavior

Journal of Chemical Technology and Biotechnology

Volumn 85, Issue 12, 2010, Pages 1588-1596

  Lassalle, Verónica ^a   Ferreira, María Luján ^b  

^a INQUISUR   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

Biomaterials; Insulin; PLGA; Protein delivery; Release mechanism

Indexed keywords

ANOMALOUS TRANSPORT; ASSOCIATION EFFICIENCY; AVERAGE MOLECULAR WEIGHT; COMPUTATIONAL ANALYSIS; COPOLYESTERS; DRUG DELIVERY SYSTEM; ENERGY DISPERSIVE X-RAY; FOURIER TRANSFORM INFRARED; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IN-VITRO; INSULIN RELEASE; MODEL DRUGS; NUMBER AVERAGE MOLECULAR WEIGHT; PLGA; POLYMERIC MATRICES; POLYMERIC NETWORKS; PROTEIN DELIVERY; RELEASE MECHANISM; RELEASE PROFILES; SPECTROSCOPIC TOOL; SUSTAINED RELEASE; X-RAY FLUORESCENCE SPECTROSCOPY;

BIOLOGICAL MATERIALS; COMPUTATIONAL METHODS; COPOLYMERIZATION; DRUG DELIVERY; DRUG INTERACTIONS; FLUORESCENCE SPECTROSCOPY; FOURIER TRANSFORMS; HYDROPHILICITY; MATHEMATICAL MODELS; MOLECULAR WEIGHT; OLIGOMERS; POLYMERS; PROTEINS;

INSULIN;

COPOLYMER; INSULIN; POLY(LACTIC CO GLYCOLIC)COPOLYMER; POLYESTER; UNCLASSIFIED DRUG;

ARTICLE; DRUG DELIVERY SYSTEM; ENERGY DISPERSIVE X RAY; INFRARED SPECTROSCOPY; PROTEIN INTERACTION; SUSTAINED DRUG RELEASE; X RAY; X RAY FLUORESCENCE;

EID: 78449263194     PISSN: 02682575     EISSN: 10974660     Source Type: Journal    
DOI: 10.1002/jctb.2470     Document Type: Article

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