메뉴 건너뛰기




Volumn 6, Issue 10, 2010, Pages 1-12

Four novel loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation In vivo

(57)  Kamran Ikram, M a   Xueling, Sim b   Jensen, Richard A c,d   Cotch, Mary Frances e   Hewitt, Alex W f   Ikram, M Arfan a   Wang, Jie Jin f,g   Klein, Ronald h   Klein, Barbara E K h   Breteler, Monique M B a   Cheung, Ning f   Liew, Gerald g   Mitchell, Paul g   Uitterlinden, Andre G a   Rivadeneira, Fernando a   Hofman, Albert a   de Jong, Paulus T V M i,j   van Duijn, Cornelia M a   Kao, Linda k   Cheng, Ching Yu l,m   more..


Author keywords

[No Author keywords available]

Indexed keywords

ATAXIN 2; MYOCYTE ENHANCER FACTOR 2; NEUROMEDIN B; PROTEIN RASIP1; PROTEIN SH2B3; PROTEIN TYROSINE PHOSPHATASE SHP 2; PROTEIN VTA1; RAS PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 1;

EID: 78449249315     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1001184     Document Type: Article
Times cited : (120)

References (47)
  • 1
    • 33847231568 scopus 로고    scopus 로고
    • Coronary microvascular dysfunction
    • Camini PG, Crea F (2007) Coronary microvascular dysfunction. N Engl J Med 356: 830-840.
    • (2007) N Engl J Med , vol.356 , pp. 830-840
    • Camini, P.G.1    Crea, F.2
  • 2
    • 33644840046 scopus 로고    scopus 로고
    • Genetic susceptibility to coronary artery disease: From promise to progress
    • Watkins H, Farrall M (2006) Genetic susceptibility to coronary artery disease: from promise to progress. Nat Rev Genet 7: 163-173.
    • (2006) Nat Rev Genet , vol.7 , pp. 163-173
    • Watkins, H.1    Farrall, M.2
  • 3
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium (2007) Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447: 661-678.
    • (2007) Nature , vol.447 , pp. 661-678
  • 4
    • 0033503919 scopus 로고    scopus 로고
    • Methods for evaluation of retinal microvascular abnormalities associated with hypertension/ sclerosis in the Atherosclerosis Risk in Communities Study
    • Hubbard LD, Brothers RJ, King WN, Clegg LX, Klein R, et al. (1999) Methods for evaluation of retinal microvascular abnormalities associated with hypertension/ sclerosis in the Atherosclerosis Risk in Communities Study. Ophthalmology 106: 2269-2280.
    • (1999) Ophthalmology , vol.106 , pp. 2269-2280
    • Hubbard, L.D.1    Brothers, R.J.2    King, W.N.3    Clegg, L.X.4    Klein, R.5
  • 5
    • 3142616795 scopus 로고    scopus 로고
    • Are retinal arteriolar or venular diameters associated with markers for cardiovascular disorders? The Rotterdam Study
    • Ikram MK, De Jong FJ, Vingerling JR, Witteman JC, Hofman A, et al. (2004) Are retinal arteriolar or venular diameters associated with markers for cardiovascular disorders? The Rotterdam Study. Invest Ophthalmol Vis Sci 45: 2129-2134.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 2129-2134
    • Ikram, M.K.1    De Jong, F.J.2    Vingerling, J.R.3    Witteman, J.C.4    Hofman, A.5
  • 6
    • 9244261055 scopus 로고    scopus 로고
    • Hypertensive retinopathy
    • Wong TY, Mitchell P (2004) Hypertensive retinopathy. N Engl J Med 351: 2310-2317.
    • (2004) N Engl J Med , vol.351 , pp. 2310-2317
    • Wong, T.Y.1    Mitchell, P.2
  • 7
    • 1042276731 scopus 로고    scopus 로고
    • Atherosclerosis Risk in Communities Study. Retinal arteriolar diameter and risk for hypertension
    • Wong TY, Klein R, Sharrett AR, Duncan BB, Couper DJ, et al. (2004) Atherosclerosis Risk in Communities Study. Retinal arteriolar diameter and risk for hypertension. Ann Intern Med 140: 248-255.
    • (2004) Ann Intern Med , vol.140 , pp. 248-255
    • Wong, T.Y.1    Klein, R.2    Sharrett, A.R.3    Duncan, B.B.4    Couper, D.J.5
  • 8
    • 0037093011 scopus 로고    scopus 로고
    • Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons
    • Wong TY, Klein R, Sharrett AR, Schmidt MI, Pankow JS, et al. (2002) Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons. JAMA 287: 2528-2533.
    • (2002) JAMA , vol.287 , pp. 2528-2533
    • Wong, T.Y.1    Klein, R.2    Sharrett, A.R.3    Schmidt, M.I.4    Pankow, J.S.5
  • 9
    • 48249133296 scopus 로고    scopus 로고
    • Retinal and cerebral microvascular signs and diabetes: The age, gene/environment susceptibility-Reykjavik study
    • Qiu C, Cotch MF, Sigurdsson S, Garcia M, Klein R, et al. (2008) Retinal and cerebral microvascular signs and diabetes: the age, gene/environment susceptibility-Reykjavik study. Diabetes 57: 1645-1650.
    • (2008) Diabetes , vol.57 , pp. 1645-1650
    • Qiu, C.1    Cotch, M.F.2    Sigurdsson, S.3    Garcia, M.4    Klein, R.5
  • 10
    • 70849089543 scopus 로고    scopus 로고
    • Prediction of incident stroke events based on retinal vessel caliber: A systematic review and individual-participant meta-analysis
    • McGeeshan K, Liew G, Macaskill P, Irwig L, Klein R, et al. (2009) Prediction of incident stroke events based on retinal vessel caliber: a systematic review and individual-participant meta-analysis. Am J Epidemiol 170: 1323-1332.
    • (2009) Am J Epidemiol , vol.170 , pp. 1323-1332
    • McGeeshan, K.1    Liew, G.2    Macaskill, P.3    Irwig, L.4    Klein, R.5
  • 11
    • 70349086163 scopus 로고    scopus 로고
    • Metaanalysis: Retinal vessel caliber and risk for coronary heart disease
    • McGeechan K, Liew G, Macaskill P, Irwig L, Klein R, et al. (2009) Metaanalysis: retinal vessel caliber and risk for coronary heart disease. Ann Intern Med 151: 404-413.
    • (2009) Ann Intern Med , vol.151 , pp. 404-413
    • McGeechan, K.1    Liew, G.2    Macaskill, P.3    Irwig, L.4    Klein, R.5
  • 12
    • 30344486256 scopus 로고    scopus 로고
    • Retinal vessel diameters and cerebral small vessel disease: The Rotterdam Scan Study
    • Ikram MK, De Jong FJ, Van Dijk EJ, Prins ND, Hofman A, et al. (2006) Retinal vessel diameters and cerebral small vessel disease: The Rotterdam Scan Study. Brain 129: 182-188.
    • (2006) Brain , vol.129 , pp. 182-188
    • Ikram, M.K.1    De Jong, F.J.2    Van Dijk, E.J.3    Prins, N.D.4    Hofman, A.5
  • 13
    • 33845875714 scopus 로고    scopus 로고
    • Associations between findings on cranial magnetic resonance imaging and retinal photography in the elderly: The Cardiovascular Health Study
    • Longstreth W, Jr., Larsen EK, Klein R, Wong TY, Sharrett AR, et al. (2007) Associations between findings on cranial magnetic resonance imaging and retinal photography in the elderly: the Cardiovascular Health Study. Am J Epidemiol 165: 78-84.
    • (2007) Am J Epidemiol , vol.165 , pp. 78-84
    • Longstreth Jr., W.1    Larsen, E.K.2    Klein, R.3    Wong, T.Y.4    Sharrett, A.R.5
  • 14
    • 56249130741 scopus 로고    scopus 로고
    • Retinal vascular caliber and age-related macular degeneration: The Singapore Malay Eye Study
    • Jeganathan VS, Kawasaki R, Wang JJ, Aung T, Mitchell P, et al. (2008) Retinal vascular caliber and age-related macular degeneration: the Singapore Malay Eye Study. Am J Ophthalmol 146: 954-959.
    • (2008) Am J Ophthalmol , vol.146 , pp. 954-959
    • Jeganathan, V.S.1    Kawasaki, R.2    Wang, J.J.3    Aung, T.4    Mitchell, P.5
  • 15
    • 44449165625 scopus 로고    scopus 로고
    • Relationship of retinal vascular caliber with diabetes and retinopathy: The Multi- Ethnic Study of Atherosclerosis (MESA)
    • Nguyen TT, Wang JJ, Sharrett AR, Islam FM, Klein R, et al. (2008) Relationship of retinal vascular caliber with diabetes and retinopathy: the Multi- Ethnic Study of Atherosclerosis (MESA). Diabetes Care 31: 544-549.
    • (2008) Diabetes Care , vol.31 , pp. 544-549
    • Nguyen, T.T.1    Wang, J.J.2    Sharrett, A.R.3    Islam, F.M.4    Klein, R.5
  • 16
    • 34748903665 scopus 로고    scopus 로고
    • Retinal vessel caliber and microvascular and macrovascular disease in type 2 diabetes: XXI: The Wisconsin Epidemiologic Study of Diabetic Retinopathy
    • Klein R, Klein BE, Moss SE, Wong TY (2007) Retinal vessel caliber and microvascular and macrovascular disease in type 2 diabetes: XXI: the Wisconsin Epidemiologic Study of Diabetic Retinopathy. Ophthalmology 114: 1884-1892.
    • (2007) Ophthalmology , vol.114 , pp. 1884-1892
    • Klein, R.1    Klein, B.E.2    Moss, S.E.3    Wong, T.Y.4
  • 17
    • 33645834302 scopus 로고    scopus 로고
    • Genome-wide linkage study of retinal vessel diameters in the Beaver Dam Eye Study
    • Xing C, Klein BE, Klein R, Jun G, Lee KE, et al. (2006) Genome-wide linkage study of retinal vessel diameters in the Beaver Dam Eye Study. Hypertension 47: 797-802.
    • (2006) Hypertension , vol.47 , pp. 797-802
    • Xing, C.1    Klein, B.E.2    Klein, R.3    Jun, G.4    Lee, K.E.5
  • 18
    • 33645838828 scopus 로고    scopus 로고
    • Genetic determinants of retinal vascular caliber: Additional insights into hypertension pathogenesis
    • Wang JJ, Wong TY (2006) Genetic determinants of retinal vascular caliber: additional insights into hypertension pathogenesis. Hypertension 47: 644-645.
    • (2006) Hypertension , vol.47 , pp. 644-645
    • Wang, J.J.1    Wong, T.Y.2
  • 19
    • 34250305961 scopus 로고    scopus 로고
    • Apolipoprotein E gene polymorphisms and retinal vascular signs: The atherosclerosis risk in communities (ARIC) study
    • Liew G, Shankar A, Wang JJ, Klein R, Bray MS, et al. (2007) Apolipoprotein E gene polymorphisms and retinal vascular signs: the atherosclerosis risk in communities (ARIC) study. Arch Ophthalmol 125: 813-818.
    • (2007) Arch Ophthalmol , vol.125 , pp. 813-818
    • Liew, G.1    Shankar, A.2    Wang, J.J.3    Klein, R.4    Bray, M.S.5
  • 20
    • 34548058167 scopus 로고    scopus 로고
    • Complement factor h polymorphism, inflammatory mediators, and retinal vessel diameters: The rotterdam study
    • De Jong FJ, Ikram MK, Despriet DD, Uitterlinden AG, Hofman A, et al. (2007) Complement factor h polymorphism, inflammatory mediators, and retinal vessel diameters: the rotterdam study. Invest Ophthalmol Vis Sci 48: 3014-3018.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 3014-3018
    • De Jong, F.J.1    Ikram, M.K.2    Despriet, D.D.3    Uitterlinden, A.G.4    Hofman, A.5
  • 21
    • 63449100039 scopus 로고    scopus 로고
    • Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from five cohorts
    • Psaty BM, O'Donnell CJ, Gudnason V, Lunetta KL, Folsom AR, et al. (2009) Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from five cohorts. Circ Cardiovasc Genet 2: 73-80.
    • (2009) Circ Cardiovasc Genet , vol.2 , pp. 73-80
    • Psaty, B.M.1    O'Donnell, C.J.2    Gudnason, V.3    Lunetta, K.L.4    Folsom, A.R.5
  • 22
    • 34247126863 scopus 로고    scopus 로고
    • Age, Gene/Environment Susceptibility-Reykjavik Study: Multidisciplinary applied phenomics
    • Harris TB, Launer LJ, Eiriksdottir G, Kjartansson O, Jonsson PV, et al. (2007) Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomics. Am J Epidemiol 165: 1076-1087.
    • (2007) Am J Epidemiol , vol.165 , pp. 1076-1087
    • Harris, T.B.1    Launer, L.J.2    Eiriksdottir, G.3    Kjartansson, O.4    Jonsson, P.V.5
  • 23
    • 0007711060 scopus 로고
    • The ARIC investigators
    • The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives
    • The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives (1989) The ARIC investigators. Am J Epidemiol 129: 687-702.
    • (1989) Am J Epidemiol , vol.129 , pp. 687-702
  • 26
    • 74949122838 scopus 로고    scopus 로고
    • Twins Eye Study in Tasmania (TEST): Rationale and Methodology to Recruit and Examine Twins
    • Mackey DA, Mackinnon JR, Brown SA, Kearns LS, Ruddle JB, et al. (2009) Twins Eye Study in Tasmania (TEST): Rationale and Methodology to Recruit and Examine Twins. Twin Res Hum Genet 12: 441-454.
    • (2009) Twin Res Hum Genet , vol.12 , pp. 441-454
    • Mackey, D.A.1    Mackinnon, J.R.2    Brown, S.A.3    Kearns, L.S.4    Ruddle, J.B.5
  • 27
    • 0034659685 scopus 로고    scopus 로고
    • Genetic and environmental factors in age-related nuclear cataracts in monozygotic and dizygotic twins
    • Hammond CJ, Snieder H, Spector TD, Gilbert CE (2000) Genetic and environmental factors in age-related nuclear cataracts in monozygotic and dizygotic twins. N Engl J Med 342: 1786-1790.
    • (2000) N Engl J Med , vol.342 , pp. 1786-1790
    • Hammond, C.J.1    Snieder, H.2    Spector, T.D.3    Gilbert, C.E.4
  • 28
    • 0029161079 scopus 로고
    • The risk of myocardial infarction associated with antihypertensive drug therapies
    • Psaty BM, Heckbert SR, Koepsell TD, Siscovick DS, Raghunathan TE, et al. (1995) The risk of myocardial infarction associated with antihypertensive drug therapies. JAMA 274: 620-625.
    • (1995) JAMA , vol.274 , pp. 620-625
    • Psaty, B.M.1    Heckbert, S.R.2    Koepsell, T.D.3    Siscovick, D.S.4    Raghunathan, T.E.5
  • 30
    • 67349085063 scopus 로고    scopus 로고
    • Genome-wide association study identifies eight loci associated with blood pressure
    • Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, et al. (2009) Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet 41: 666-676.
    • (2009) Nat Genet , vol.41 , pp. 666-676
    • Newton-Cheh, C.1    Johnson, T.2    Gateva, V.3    Tobin, M.D.4    Bochud, M.5
  • 31
    • 77954143522 scopus 로고    scopus 로고
    • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
    • Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, et al. (2010) Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet 42: 579-589.
    • (2010) Nat Genet , vol.42 , pp. 579-589
    • Voight, B.F.1    Scott, L.J.2    Steinthorsdottir, V.3    Morris, A.P.4    Dina, C.5
  • 32
    • 0035996273 scopus 로고    scopus 로고
    • Lipid hydroperoxide stimulates leukocyte-endothelium interaction in the retinal microcirculation
    • Tamai K, Matsubara A, Tomida K, Matsuda Y, Morita H, et al. (2002) Lipid hydroperoxide stimulates leukocyte-endothelium interaction in the retinal microcirculation. Exp Eye Res 75: 69-75.
    • (2002) Exp Eye Res , vol.75 , pp. 69-75
    • Tamai, K.1    Matsubara, A.2    Tomida, K.3    Matsuda, Y.4    Morita, H.5
  • 33
    • 0032104473 scopus 로고    scopus 로고
    • Induction of nitric oxide synthase in human vascular smooth muscle: Interactions between proinflammatory cytokines
    • Chester AH, Borland JA, Buttery LD, Mitchell JA, Cunningham DA, et al. (1998) Induction of nitric oxide synthase in human vascular smooth muscle: interactions between proinflammatory cytokines. Cardiovasc Res 38: 814-821.
    • (1998) Cardiovasc Res , vol.38 , pp. 814-821
    • Chester, A.H.1    Borland, J.A.2    Buttery, L.D.3    Mitchell, J.A.4    Cunningham, D.A.5
  • 34
    • 33745644311 scopus 로고    scopus 로고
    • Retinal vascular caliber, cardiovascular risk factors and inflammation: The Multi-Ethnic Study of Atherosclerosis
    • Wong TY, Islam FM, Klein R, Klein BE, Cotch MF, et al. (2006) Retinal vascular caliber, cardiovascular risk factors and inflammation: the Multi-Ethnic Study of Atherosclerosis. Invest Ophthalmol Vis Sci 47: 2341-2350.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 2341-2350
    • Wong, T.Y.1    Islam, F.M.2    Klein, R.3    Klein, B.E.4    Cotch, M.F.5
  • 35
    • 67349093988 scopus 로고    scopus 로고
    • RASIP1 is required for endothelial cell motility, angiogenesis and vessel formation
    • Xu K, Chong DC, Rankin SA, Zorn AM, Cleaver O (2009) RASIP1 is required for endothelial cell motility, angiogenesis and vessel formation. Dev Biol 329: 269-279.
    • (2009) Dev Biol , vol.329 , pp. 269-279
    • Xu, K.1    Chong, D.C.2    Rankin, S.A.3    Zorn, A.M.4    Cleaver, O.5
  • 36
    • 37749011364 scopus 로고    scopus 로고
    • Structural Basis of Vta1 Function in the Multivesicular Body Sorting Pathway
    • Xiao J, Xia H, Zhou J, Azmi IF, Davies BA, et al. (2008) Structural Basis of Vta1 Function in the Multivesicular Body Sorting Pathway. Dev Cell 14: 37-49.
    • (2008) Dev Cell , vol.14 , pp. 37-49
    • Xiao, J.1    Xia, H.2    Zhou, J.3    Azmi, I.F.4    Davies, B.A.5
  • 37
    • 15244346716 scopus 로고    scopus 로고
    • Neuromedin B and its receptor are mitogens in both normal and malignant epithelial cells lining the colon
    • Matusiak D, Glover S, Nathaniel R, Matkowskyj K, Yang J, et al. (2005) Neuromedin B and its receptor are mitogens in both normal and malignant epithelial cells lining the colon. Am J Physiol Gastrointest Liver Physiol 288: 718-728.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.288 , pp. 718-728
    • Matusiak, D.1    Glover, S.2    Nathaniel, R.3    Matkowskyj, K.4    Yang, J.5
  • 38
    • 58149091678 scopus 로고    scopus 로고
    • Shared and distinct genetic variants in type 1 diabetes and celiac disease
    • Smyth DJ, Plagnol V, Walker NM, Cooper JD, Downes K, et al. (2008) Shared and distinct genetic variants in type 1 diabetes and celiac disease. N Engl J Med 359: 2767-2777.
    • (2008) N Engl J Med , vol.359 , pp. 2767-2777
    • Smyth, D.J.1    Plagnol, V.2    Walker, N.M.3    Cooper, J.D.4    Downes, K.5
  • 39
    • 70350644759 scopus 로고    scopus 로고
    • A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium
    • Soranzo N, Spector TD, Mangino M, Kühnel B, Rendon A, et al. (2009) A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet 41: 1182-1190.
    • (2009) Nat Genet , vol.41 , pp. 1182-1190
    • Soranzo, N.1    Spector, T.D.2    Mangino, M.3    Kühnel, B.4    Rendon, A.5
  • 40
    • 70350646902 scopus 로고    scopus 로고
    • Multiple loci influence erythrocyte phenotypes in the CHARGE consortium
    • Ganesh SK, Zakai NA, Van Rooij FJ, Soranzo N, Smith AV, et al. (2009) Multiple loci influence erythrocyte phenotypes in the CHARGE consortium. Nat Genet 41: 1191-1198.
    • (2009) Nat Genet , vol.41 , pp. 1191-1198
    • Ganesh, S.K.1    Zakai, N.A.2    Van Rooij, F.J.3    Soranzo, N.4    Smith, A.V.5
  • 41
  • 42
    • 17644389201 scopus 로고    scopus 로고
    • Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation
    • Ma K, Chan JK, Zhu G, Wu Z (2005) Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation. Mol Cell Biol 25: 3575-3582.
    • (2005) Mol Cell Biol , vol.25 , pp. 3575-3582
    • Ma, K.1    Chan, J.K.2    Zhu, G.3    Wu, Z.4
  • 45
    • 0030775936 scopus 로고    scopus 로고
    • Risk of endometrial cancer in relation to use of combined oral contra-ceptives: A practitioner's guide to meta-analysis
    • Schlesselman JJ (1997) Risk of endometrial cancer in relation to use of combined oral contra-ceptives: a practitioner's guide to meta-analysis. Human Reprod 12: 1851-1863.
    • (1997) Human Reprod , vol.12 , pp. 1851-1863
    • Schlesselman, J.J.1
  • 46
    • 34548493072 scopus 로고    scopus 로고
    • Control of the mean number of false discoveries, Bonferroni and stability of multiple testing
    • Gordon A, Glazko G, Qiu X, Yakovlev A (2007) Control of the mean number of false discoveries, Bonferroni and stability of multiple testing. Ann Appl Statistics 1: 179-190.
    • (2007) Ann Appl Statistics , vol.1 , pp. 179-190
    • Gordon, A.1    Glazko, G.2    Qiu, X.3    Yakovlev, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.