An S/MAR-based l1 retrotransposition cassette mediates sustained levels of insertional mutagenesis without suffering from epigenetic silencing of DNA methylation

Epigenetics

Volumn 5, Issue 7, 2010, Pages 601-611

  Rangasamy, Danny ^a  

^a Australian National University   (Australia)

Author keywords

DNA methylation; EBNA1; Episome; Minicircle; Nonviral; Retrotransposition; S MAR; Somatic mutagenesis; Vector

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; EPSTEIN BARR VIRUS ANTIGEN 1; MINICIRCLE DNA;

ARTICLE; CELL CULTURE; CELL LINE; CELL STRAIN HEK293; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; GENE CASSETTE; GENE INSERTION SEQUENCE; GENE SILENCING; GENE VECTOR; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; LONG INTERSPERSED REPEAT; MATRIX ATTACHMENT REGION; MUTAGENESIS; SOMATIC CELL GENETICS;

MAMMALIA;

EID: 78449244882     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.5.7.12647     Document Type: Article

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