Mannose-Binding Lectin (MBL) substitution: Recovery of opsonic function in vivo lags behind MBL serum levels

Journal of Immunology

Volumn 183, Issue 5, 2009, Pages 3496-3504

  Brouwer, Nannette ^a   Frakking, Florine N J ^b   Van De Wetering, Marianne D ^b   Van Houdt, Michel ^a   Hart, Margreet ^a   Budde, Ilona Kleine ^c   Strengers, Paul F W ^c   Laursen, Inga ^d   Houen, Gunnar ^d   Roos, Dirk ^a   Jensenius, Jens C ^e   Caron, Huib N ^b   Dolman, Koert M ^a,b   Kuijpers, Taco W ^a,b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b EMMA CHILDREN S HOSPITAL   (Netherlands)

^c Departments of Medical Psychology   (Netherlands)

^d STATENS SERUM INSTITUT   (Denmark)

^e AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; MANNAN BINDING LECTIN ASSOCIATED SERINE PROTEINASE; MANNOSE BINDING LECTIN; OPSONIN; ZYMOSAN; MASP2 PROTEIN, HUMAN;

ABSENCE OF SIDE EFFECTS; ARTICLE; BIOLOGICAL ACTIVITY; CHILD; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; COHORT ANALYSIS; COMPLEMENT ACTIVATION; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG PROTEIN BINDING; DRUG SAFETY; ENZYME ACTIVITY; FEMALE; HUMAN; INFANT; MALE; NEUTROPENIA; NEUTROPHIL; NEWBORN; PHAGOCYTOSIS; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; REPEATED DRUG DOSE; SCHOOL CHILD; SUBSTITUTION THERAPY; ADOLESCENT; AMINO ACID SUBSTITUTION; BLOOD; CHEMICALLY INDUCED DISORDER; ENZYMOLOGY; GENETICS; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; PROSPECTIVE STUDY;

ADOLESCENT; AMINO ACID SUBSTITUTION; CHILD; CHILD, PRESCHOOL; COMPLEMENT ACTIVATION; FEMALE; HUMANS; MALE; MANNOSE-BINDING LECTIN; MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES; NEUTROPENIA; OPSONIN PROTEINS; PHAGOCYTOSIS; PROSPECTIVE STUDIES;

EID: 70349254225     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0900445     Document Type: Article

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