Quantitative structure-activity relationship of organosulphur compounds as Soybean 15-Lipoxygenase inhibitors using CoMFA and CoMSIA

Chemical Biology and Drug Design

Volumn 76, Issue 6, 2010, Pages 511-517

  Caballero, Julio ^a   Fernández, Michael ^b   Coll, Deysma ^c  

^a UNIVERSIDAD DE TALCA   (Chile)

^b KYUSHU INSTITUTE OF TECHNOLOGY   (Japan)

^c PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

CoMFA; CoMSIA; Garlic; Organosulphur compounds; Quantitative structure activity relationships; Soybean 15 lipoxygenase

Indexed keywords

LIPOXYGENASE INHIBITOR; ORGANOSULFUR DERIVATIVE;

ARTICLE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; COMPUTER PROGRAM; ENZYME ACTIVITY; ENZYME INHIBITION; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SOYBEAN;

ARACHIDONATE 15-LIPOXYGENASE; COMPUTER SIMULATION; INHIBITORY CONCENTRATION 50; LIGANDS; LIPOXYGENASE INHIBITORS; MODELS, CHEMICAL; MODELS, MOLECULAR; ORGANIC CHEMICALS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SOYBEANS; SULFUR;

ALLIUM SATIVUM; GLYCINE MAX;

EID: 78349273656     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2010.01039.x     Document Type: Article

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