Streptozotocin causes pancreatic beta cell failure via early and sustained biochemical and cellular alterations

Experimental and Clinical Endocrinology and Diabetes

Volumn 118, Issue 10, 2010, Pages 699-707

  Adeghate, E ^a   Hameed, R S ^a   Ponery, A S ^a   Tariq, S ^a   Sheen, R S ^a   Shaffiullah, M ^a   Donath T ^b  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

beta cell failure; catecholamines; diabetes mellitus; electronmicroscopy; immunohistochemistry; islet; streptozotocin

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; ADRENALIN; GLUCAGON; GLUCOSE; INSULIN; NORADRENALIN; STREPTOZOCIN;

ADRENALIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEGRANULATION; ELECTRON MICROSCOPY; GLUCAGON BLOOD LEVEL; GLUCAGON RELEASE; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPOINSULINEMIA; IMMUNOREACTIVITY; INSULIN BLOOD LEVEL; INSULIN RELEASE; MALE; NONHUMAN; NORADRENALIN BLOOD LEVEL; PANCREAS INSUFFICIENCY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; WEIGHT REDUCTION;

ANIMALS; CELL DEGRANULATION; DIABETES MELLITUS, EXPERIMENTAL; EPINEPHRINE; GLUCAGON; HYDROXYINDOLEACETIC ACID; HYPERGLYCEMIA; INSULIN; INSULIN-SECRETING CELLS; MALE; NOREPINEPHRINE; OSMOLAR CONCENTRATION; PANCREAS; RATS; RATS, WISTAR; SECRETORY VESICLES; STREPTOZOCIN; TIME FACTORS; WEIGHT LOSS;

EID: 78349269171     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0030-1253395     Document Type: Article

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