Effects of streptozotocin-induced type 1 diabetes mellitus on total protein concentrations and cation contents in the isolated pancreas, parotid, submandibular, and lacrimal glands of rats

Annals of the New York Academy of Sciences

Volumn 1084, Issue , 2006, Pages 503-519

  Changrani, Navin R ^a   Chonkar, Apurva ^a   Adeghate, Ernest ^b   Singh, Jaipaul ^a  

^a UNIVERSITY OF CENTRAL LANCASHIRE   (United Kingdom)

^b UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

Cations; Diabetes; Lacrimal; Pancreas; Parotid; Rat; Streptozotocin; Submandibular; Total protein

Indexed keywords

CALCIUM ION; CATION; COPPER ION; GLUCOSE; INSULIN; IRON; MAGNESIUM ION; POTASSIUM ION; PROTEIN; SODIUM ION; STREPTOZOCIN; ZINC ION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ATOMIC ABSORPTION SPECTROMETRY; CONFERENCE PAPER; CONTROLLED STUDY; EXOCRINE GLAND; FLAME PHOTOMETRY; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; LACRIMAL GLAND; MALE; NONHUMAN; PANCREAS; PAROTID GLAND; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE; STREPTOZOCIN DIABETES; SUBMANDIBULAR GLAND; ANIMAL; ARTICLE; EXPERIMENTAL DIABETES MELLITUS; LACRIMAL APPARATUS; METABOLISM; WISTAR RAT;

ANIMALIA; RATTUS;

ANIMALS; CATIONS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; LACRIMAL APPARATUS; MALE; PANCREAS; PAROTID GLAND; PROTEINS; RATS; RATS, WISTAR; SUBMANDIBULAR GLAND;

EID: 34447133082     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1372.019     Document Type: Conference Paper

References (32)

1. DANIELSSON, A. 1974. Effects of glucose, insulin and glucagons on amylase secretion from incubated mouse pancreas. Pflugers Arch. 348: 333-342.
2. KUMAR P. & M. CLARK. 2002. Diabetes mellitis and other disorders of metabolism. In Clinical Medicine. P. Kumar & M. Clark, Eds.: 1069-1121. WB Saunders.
3. ZIMMET, P., K.G. ALBERTI & J. SHAW. 2001. Global and societal implications of the diabetes epidemic. Nature 414: 782-787.
4. WILLIAMS, J.C. & G. PICKUP. 1998. Complications of diabetes mellitis. In Handbook of Diabetes. 14-18 Cambridge University Press. Blackwell Science. Livingston, UK.
5. YAGO, M.D., E. ADEGHATE & J. SINGH. 1999. Interactions between the endocrine and exocrine pancreas. Effects of islet hormones, secretagogues, and nerve stimulation. In Neural Regulation in the Vertebrate Endocrine System: Neuroendocrine Regulation. R.A. Prasada Rao & R. Peters. Eds.: 197-217. Kluwer Academic/Plenum. New York.
6. MARTINI, F.H. & K. WELCH. 2004. The digestive system. In Applications Manual to Accompany Fundamentals of Anatomy & Physiology, 6th ed. 136-147. Pearson Education. Cambridge, UK.
7. BASTIAN, J.F. 1994. Structures and functions of the pancreas. In An Illustrated Review of Anatomy & Physiology. 40-41. Harper Collins College Publishers. New York.
8. WIDMAIER, E.P., H. RAFF & K.T. STRANG. 2006. Digestive system. In Vander's Human Physiology - The Mechanisms of Body Function. 575-601 McGraw-Hill London, UK.
9. TORTORA, G.J. & S.R. GRABOWSKI. 2003. A detailed review of digestive system. In Principles of Anatomy & Physiology, 10th ed. 531-534, 858-864, 874-888. John Wiley & Sons. London, UK.
10. SINGH, J., E. ADEGHATE, S. APARICO & R. HOPKIN. 2004. Exocrine pancreatic insufficiency in diabetes mellitus. Int. J. Diabetes Metab. 12: 35-43.
11. BERNE, R.M., M.N. LEVY, B.M. KOEPPEN & B.A. STANTON. 1998. Adetailed review of the digestive system. In Physiology, 4th ed. 632-637. New York. Mosby.
12. PEARSON, G.T., J. SINGH & O.H. PETERSEN. 1984. Adrenergic nervous control of cAMP-mediated amylase secretion in the rat pancreas. Am. J. Physiol. 246: G563-G573.
13. PATEL, R., M.D. YAGO, M. MANAS, et al. 2004. Mechanism of exocrine pancreatic insufficiency in streptozotocin-induced diabetes mellitus in rat: effect of cholecystokinin-octapeptide. Mol. Cell. Biochem. 261: 105-110.
14. PATEL, R. 2005. Cellular mechanism of exocrine pancreatic insufficiency in diabetes mellitus. PhD thesis, University of Central Lancashire.
15. BRADFORD, M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254.
16. BOUREY, R.E., L. KORANYI, D.E. JAMES, et al. 1990. Effects of altered glucose homeostasis on glucose transporter expression in skeletal muscle of the rat. J. Clin. Invest. 86: 542-547.
17. MAHAY, S., W. WINLOW, J. SINGH, et al. 2002. Effects of ageing on morphology and α-amylase release in the isolated rat parotid gland. J. Physiol. 543P: 15P.
18. MAHAY, S.K. 2005. The effects of aging and streptozotocin (STZ)-induced diabetes mellitus on the rodent parotid gland. PhD thesis, University of Central Lancashire.
19. WISDOM, D., J. SINGH, P.J. CAMELLO, et al. 1993. Effect of secretion on vagal stimulation-evoked exocrine pancreatic secretion in the rat. Rev. Esp. Fisiol. 49: 31-35.
20. 2+ ionophore A23187 and 12-O-tetradecanoylphorbol 13-acetate. Biochem. J. 235: 125-131.
21. WISDOM, D.M., G.M. SALIDO, L.M. BALDWIN & J. SINGH. 1996. The role of magnesium in regulating CCK-8-evoked secretory responses in the exocrine rat pancreas. Mol. Cell. Biochem. 154: 123-132.
22. CHAUSMER, A. 1998. Zinc, insulin and diabetes. J. Am. Coll. Nutr. 17: 109-115.
23. HONNORAT, J., M. ACCOMINOTTI, C. BROUSSOLLE, et al. 1992. Effects of diabetes type and treatment on zinc status in diabetes mellitus. Biol. Trace Elem. Res. 32: 311-316.
24. SATO, T.P. & K. MIKAMI. 2002. Recovery of a patient with a recurrent dysgeusia monitored by salivary variables and serum zinc content. Pathophysiology 8: 275-281.
25. JONES, L.T. 1966. The lacrimal system and its treatment. Am. J. Ophthalmol. 62: 503-523.
26. ANDERSON, R.A., A.M. ROUSSEL, N. ZOUARI, et al. 2001. Potential antioxidant effects of zinc and chromium supplementation in people with type 2 diabetes mellitus. J. Am. Coll. Nutr. 20: 212-218.
27. MATA, A.D., D. MARQUES, M.F. MESQUITA & J. SINGH. 2002. Effect of extracellular magnesium on secretagogue-evoked amylase secretion in the isolated rat parotid gland segments. Mag. Res. 15: 161-165.
28. 2+ signals and control of ion channels in exocrine acinar cells. J. Physiol. 448: 1-51.
29. WOODS, N.M., K.S. CUTHBERTSON & P.H. COBBOLD. 1986. Repetitive transient rises in cytoplasmic free calcium in hormone-stimulated hepatocytes. Nature 319: 600-602.
30. ISBIR, T., L. TAMER, A. TAYLOR & M. ISBIR. 1994. Zinc, copper and magnesium status in insulin-dependent diabetes. Diabetes Res. 26: 41-45.
31. MATHER, H.M. & G.E. LEVIN. 1979. Magnesium status in diabetes. Lancet 1: 924.
32. FAILLA, M.L. & C.Y. GARDELL. 1985. Influence of spontaneous diabetes on tissue status of zinc, copper, and magnesium in the BB Wistar rat. Proc. Soc. Exp. Biol. Med. 180: 317-322.