Insulin resistance in type 1 diabetes

Diabetes/Metabolism Research and Reviews

Volumn 18, Issue 3, 2002, Pages 192-200

  Greenbaum, Carla J ^a  

^a BENAROYA RESEARCH INSTITUTE   (United States)

Author keywords

Clinical intervention trials; Insulin sensitivity; Type 1 diabetes

Indexed keywords

INSULIN; METFORMIN; NICOTINAMIDE; ORAL ANTIDIABETIC AGENT; ANTIDIABETIC AGENT;

ADULT; AUTOIMMUNE DISEASE; CELL DAMAGE; CELL FUNCTION; CHILD; CONTROLLED STUDY; DATA ANALYSIS; DISEASE SEVERITY; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; NONHUMAN; PANCREAS ISLET BETA CELL; PARAMETER; PRIORITY JOURNAL; PUBERTY; REMISSION; REVIEW; SAMPLE SIZE; ANIMAL; ANIMAL MODEL; BLOOD; GLUCOSE BLOOD LEVEL; METABOLISM; PATHOPHYSIOLOGY; SECRETION;

ANIMAL; BLOOD GLUCOSE; DIABETES MELLITUS, INSULIN-DEPENDENT; HUMAN; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; MODELS, ANIMAL; SUPPORT, NON-U.S. GOV'T; ANIMALS; DIABETES MELLITUS, TYPE 1; HUMANS;

EID: 0035985231     PISSN: 15207552     EISSN: None     Source Type: Journal    
DOI: 10.1002/dmrr.291     Document Type: Review

References (55)

1. Investigation of insulin sensitivity in treated subjects with ketosis-prone diabetes mellitus
2. The role of insulin resistance in the natural history of type 1 diabetes
3. Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function
4. Increased beta-cell secretory capacity as a mechanism for islet adaptation to nicotinic acid-induced insulin resistance
5. Effect of nicotinic acid-induced insulin resistance on pancreatic B cell function in normal and streptozocin-treated baboons
6. Banting Lecture 1990. Beta-cells in type II diabetes mellitus
7. Nicotinamide's effects on glucose metabolism in subjects at risk for IDDM
8. Nonprogression of subclinical beta-cell dysfunction among first-degree relatives of IDDM patients
9. Relationship of beta-cell function and autoantibodies to progression and nonprogression of subclinical type 1 diabetes: Follow-up of the Seattle Family Study
10. Basal and stimulated insulin levels rise with advancing puberty
11. Both insulin sensitivity and insulin clearance in children and young adults with type I (insulin-dependent) diabetes vary with growth hormone concentrations and with age
12. Natural course of insulin resistance in type I diabetes
13. Effects of age, duration and treatment of insulin- dependent diabetes mellitus on residual beta-cell function: Observations during eligibility testing for the Diabetes Control and Complications Trial (DCCT)
14. Beta-cell function recovery is not the only factor responsible for remission in type I diabetics: Evaluation of C-peptide secretion in diabetic children after first metabolic recompensation and at partial remission phase
15. Reversal of insulin resistance in type 1 diabetes following initiation of insulin treatment
16. Insulin sensitivity in the initial phase of type 1 diabetes mellitus
17. Insulin sensitivity in newly diagnosed type 1 diabetics after ketoacidosis and after three months of insulin therapy
18. A modified protocol for estimation of insulin sensitivity with the minimal model of glucose kinetics in patients with insulin-dependent diabetes
19. Determinants of clinical remission in recent-onset IDDM
20. Insulin resistance is a prominent feature of insulin-dependent diabetes
21. Characterization of insulin resistance in type I diabetes
22. Defects in B-cell function and insulin sensitivity in normoglycemic streptozotocin-treated baboons: A model of preclinical insulin-dependent diabetes
23. Changes in insulin resistance with long-term insulin therapy
24. Acute and chronic effects of hyperglycaemia on glucose metabolism
25. Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rats
26. Insulin sensitivity and responsiveness in vitro and in vivo
27. Insulin-mediated glucose disposal in type I diabetes: Evidence for insulin resistance
28. Natural course of insulin sensitivity and insulin reserve in early insulin-dependent diabetes mellitus
29. Intensive therapy in adult insulin-dependent diabetes mellitus is associated with improved insulin sensitivity and reserve: A randomized, controlled, prospective study over 5 years in newly diagnosed patients
30. Residual B-cell function in type 1 (insulin-dependent) diabetes mellitus: Its relation to clinical and metabolic features
31. Limited duration of remission of insulin dependency in children with recent overt type 1 diabetes treated with low-dose cyclosporin
32. Plasma C-peptide levels and clinical remissions in recent-onset type I diabetic patients treated with cyclosporin A and insulin
33. Hypersensitivity to insulin during remissions in cyclosporin-treated IDDM patients
34. A prospective analysis of the HOMA model. The Mexico City Diabetes Study
35. Correct homeostasis model assessment (HOMA) evaluation uses the computer program
36. Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
37. Beta-cell function evaluated by HOMA as a predictor of secondary sulphonylurea failure in type 2 diabetes
38. Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity
39. Insulin sensitivity from meal tolerance tests in normal subjects: A minimal model index
40. Quantitative indexes of beta-cell function during graded up & down glucose infusion from C-peptide minimal models
41. Type 1 diabetes manifested solely by 2 hour OGTT criteria
42. Effect of heparin on insulin-glucose interactions measured by the minimal model technique: Implications for reproducibility using this method
43. Reproducibility of insulin sensitivity measured by the minimal model method
44. Repeatability of insulin sensitivity and glucose effectiveness from the minimal model. Implications for study design
45. Can clinical factors estimate insulin resistance in type 1 diabetes?
46. Presence of islet reactive T cells and autoantibodies in children diagnosed clinically with either type 1, type 2, or atypical diabetes
47. Diabetic autoimmune markers in children and adolescents with type 2 diabetes
48. Autoimmune diabetes not requiring insulin at diagnosis (latent autoimmune diabetes of the adult): Definition, characterization, and potential prevention
49. Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus
50. Implication of specific DQB1 alleles in genetic susceptibility and resistance by identification of IDDM siblings with novel HLA-DQB1 allele and unusual DR2 and DR1 haplotypes
51. HLA-encoded susceptibility to insulin-dependent diabetes mellitus is determined by DR and DQ genes as well as their linkage disequilibria in a Chinese population
52. Genetic and immunological findings in patients with newly diagnosed insulin-dependent diabetes mellitus
53. Immunogenetics and IDDM
54. Metformin improved insulin resistance in type I, insulin-dependent, diabetic patients
55. Metformin reduces insulin requirement in type 1 (insulin-dependent) diabetes