In vivo MR imaging tracking of transplanted mesenchymal stem cells in a rabbit model of acute peripheral nerve traction injury

Journal of Magnetic Resonance Imaging

Volumn 32, Issue 5, 2010, Pages 1076-1085

  Shen, Jun ^a   Duan, Xiao Hui ^a   Cheng, Li Na ^a   Zhong, Xiao Mei ^a   Guo, Ruo Mi ^a   Zhang, Fang ^a   Zhou, Cui Ping ^a   Liang, Bi Ling ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

animals; magnetic resonance imaging; mesenchymal stem cells; peripheral nerve injury; stem cell transplantation

Indexed keywords

FLUORESCENT DYE; GADOLINIUM PENTETATE; RHODAMINE; TETRAMETHYLRHODAMINE POLYETHYLENIMINE DERIVATIVE; UNCLASSIFIED DRUG;

ACUTE PERIPHERAL NERVE TRACTION INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL LABELING; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; FOLLOW UP; GENETIC TRANSFECTION; HEMATOPOIETIC STEM CELL; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INJECTION; ISOTOPE LABELING; MESENCHYMAL STEM CELL TRANSPLANTATION; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RABBIT; RADIOLOGICAL PARAMETERS; RELATIVE SIGNAL INTENSITY; SCHWANN CELL; SCIATIC NERVE;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELL SURVIVAL; CONTRAST MEDIA; GADOLINIUM DTPA; MAGNETIC RESONANCE IMAGING; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; NERVE REGENERATION; POLYETHYLENEIMINE; RABBITS; RHODAMINES; SCIATIC NERVE;

EID: 78349256703     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.22353     Document Type: Article

References (37)

1. Hood B, Levene HB, Levi AD., Transplantation of autologous Schwann cells for the repair of segmental peripheral nerve defects. Neurosurg Focus 2009; 26: E4.
2. Mosahebi A, Fuller P, Wiberg M, Terenghi G., Effect of allogeneic Schwann cell transplantation on peripheral nerve regeneration. Exp Neurol 2002; 173: 213-223.
3. Cui L, Jiang J, Wei L, et al. Transplantation of embryonic stem cells improves nerve repair and functional recovery after severe sciatic nerve axotomy in rats. Stem Cells 2008; 26: 1356-1365.
4. Chen CJ, Ou YC, Liao SL, et al. Transplantation of bone marrow stromal cells for peripheral nerve repair. Exp Neurol 2007; 204: 443-453.
5. Shen ZL, Lassner F, Becker M, Walter GF, Bader A, Berger A., Viability of cultured nerve grafts: an assessment of proliferation of Schwann cells and fibroblasts. Microsurgery 1999; 19: 356-363.
6. Walsh S, Midha R., Practical considerations concerning the use of stem cells for peripheral nerve repair. Neurosurg Focus 2009; 26: E2.
7. Ogden A, Feng FY, Myckatyn TM, etal. Safe injection of cultured Schwann cells into peripheral nerve allografts. Microsurgery 2000; 20: 314-323.
8. Walczak P, Bulte JW., The role of noninvasive cellular imaging in developing cell-based therapies for neurodegenerative disorders. Neurodegener Dis 2007; 4: 306-313.
9. Bulte JW., In vivo MRI cell tracking: clinical studies. AJR Am J Roentgenol 2009; 193: 314-325.
10. Sykova E, Jendelova P., Magnetic resonance tracking of implanted adult and embryonic stem cells in injured brain and spinal cord. Ann N Y Acad Sci 2005; 1049: 146-160.
11. Modo M, Cash D, Mellodew K, et al. Tracking transplanted stem cell migration using bifunctional, contrast agent-enhanced, magnetic resonance imaging. Neuroimage 2002; 17: 803-811.
12. Guzman R, Uchida N, Bliss TM, et al. Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. Proc Natl Acad Sci U S A 2007; 104: 10211-10216.
13. Boussif OF, Lezoualc'h MA, Zanta MD, et al. Versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci U S A 1995; 92: 7297-7301.
14. Solchaga LA, Johnstone B, Yoo JU, Goldberg VM, Caplan AI., High variability in rabbit bone marrow-derived mesenchymal cell preparations. Cell Transplant 1999; 8: 511-519.
15. Dominici M, Le Blanc K, Mueller I, etal. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006; 8: 315-317.
16. Shen J, Zhong XM, Duan XH, et al. Magnetic resonance imaging of mesenchymal stem cells labeled with dual (MR and fluorescence) agents in rat spinal cord injury. Acad Radiol 2009; 16: 1142-1154.
17. Denizot F, Lang R., Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J Immunol Methods 1986; 89: 271-277.
18. In den Kleef JJE, Cuppen JJM,. RLSQ: T1, T2 and rho calculations, combining ratios and least squares. Magn Reson Med 1987; 5: 513-524.
19. Shen J, Zhou CP, Zhong XM, et al. MR Neurography: T1 and T2 measurements in acute peripheral nerve traction injury in rabbits. Radiology 2009; 254: 729-738.
20. Jiang Y, Jahagirdar BN, Reinhardt RL, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418: 41-49.
21. Caddick J, Kingham PJ, Gardiner NJ, Wiberg M, Terenghi G., Phenotypic and functional characteristics of mesenchymal stem cells differentiated along a Schwann cell lineage. Glia 2006; 54: 840-849.
22. Cuevas P, Carceller F, Dujovny M, et al. Peripheral nerve regeneration by bone marrow stromal cells. Neurol Res 2002; 24: 634-638.
23. Hu J, Zhu QT, Liu XL, Xu YB, Zhu JK., Repair of extended peripheral nerve lesions in rhesus monkeys using acellular allogenic nerve grafts implanted with autologous mesenchymal stem cells. Exp Neurol 2007; 204: 658-666.
24. Hou SY, Zhang HY, Quan DP, Liu XL, Zhu JK., Tissue engineered peripheral nerve grafting by differentiated bone marrow stromal cells. Neuroscience 2006; 19: 101-110.
25. Himmelreich U, Dresselaers T., Cell labeling and tracking for experimental models using magnetic resonance imaging. Methods 2009; 48: 112-124.
26. Long CM, Bulte JW., In vivo tracking of cellular therapeutics using magnetic resonance imaging. Expert Opin Biol Ther 2009; 9: 293-306.
27. Shyu WC, Chen CP, Lin SZ, Lee YJ, Li H., Efficient tracking of non-iron-labeled mesenchymal stem cells with serial MRI in chronic stroke rats. Stroke 2007; 38: 367-374.
28. Rudelius M, Daldrup-Link HE, Heinzmann U, etal. Highly efficient paramagnetic labelling of embryonic and neuronal stem cells. Eur J Nucl Med Mol Imaging 2003; 30: 1038-1044.
29. Giesel FL, Stroick M, Griebe M, et al. Gadouorine M uptake in stem cells as a new magnetic resonance imaging tracking method: an in vitro and in vivo study. Invest Radiol 2006; 41: 868-873.
30. Henning TD, Saborowski O, Golovko D, et al. Cell labeling with the positive MR contrast agent Gadouorine M. Eur Radiol 2007; 17: 1226-1234.
31. Anderson SA, Lee KK, Frank JA., Gadolinium-fullerenol as a paramagnetic contrast agent for cellular imaging. Invest Radiol 2006; 41: 332-338.
32. Klasson A, Ahren M, Hellqvist E, et al. Positive MRI contrast enhancement in THP-1 cells with Gd2O3 nanoparticles. Contrast Media Mol Imaging 2008; 3: 106-111.
33. Daldrup-Link HE, Rudelius M, Metz S, et al. Cell tracking with gadophrin-2: a bifunctional contrast agent for MR imaging, optical imaging, and fluorescence microscopy. Eur J Nucl Med Mol Imaging 2004; 31: 1312-1321.
34. Walczak P, Kedziorek DA, Gilad AA, Barnett BP, Bulte JW., Applicability and limitations of MR tracking of neural stem cells with asymmetric cell division and rapid turnover: the case of the shiverer dysmyelinated mouse brain. Magn Reson Med 2007; 58: 261-269.
35. Dezawa M., Central and peripheral nerve regeneration by transplantation of Schwann cells and transdifferentiated bone marrow stromal cells. Anat Sci Int 2002; 77: 12-25.
36. Pereira Lopes FR, Camargo de Moura Campos L, Dias Correa J Jr, et al. Bone marrow stromal cells and resorbable collagen guidance tubes enhance sciatic nerve regeneration in mice. Exp Neurol 2006; 198: 457-468.
37. Ludemann L, Wurm R, Zimmer C., Pharmacokinetic modeling of GD-DTPA extravasation in brain tumors. Invest Radiol 2002; 37: 562-570.