Comparative Study of Predictive Computational Models for Nanoparticle-Induced Cytotoxicity

Risk Analysis

Volumn 30, Issue 11, 2010, Pages 1723-1734

  Sayes, Christie ^a,b   Ivanov, Ivan ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Classification; Membrane damage; Metal oxide nanoparticles; Nanotoxicology; Predictive models

Indexed keywords

CLASSIFICATION; MEMBRANE DAMAGE; METAL OXIDE NANOPARTICLES; NANOTOXICOLOGY; PREDICTIVE MODELS;

ANIMAL CELL CULTURE; CELL CULTURE; CONSUMER PRODUCTS; FORECASTING; METALLIC COMPOUNDS; METALS; NANOPARTICLES; PACKAGING MATERIALS; PREDICTIVE CONTROL SYSTEMS; RISK ANALYSIS; RISK ASSESSMENT; ZINC OXIDE;

NANOSTRUCTURED MATERIALS;

LACTATE DEHYDROGENASE; METAL NANOPARTICLE; TITANIUM; TITANIUM DIOXIDE; ZIRCONIUM; ZIRCONIUM OXIDE;

COMPARATIVE STUDY; MEMBRANE; NANOTECHNOLOGY; NUMERICAL MODEL; PHOSPHATE; RISK ASSESSMENT; TOXICITY;

ANIMAL; ARTICLE; CELL LINE; COCULTURE; COMPARATIVE STUDY; COMPUTER SIMULATION; METABOLISM; PARTICLE SIZE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT;

ANIMALS; CELL LINE, TRANSFORMED; COCULTURE TECHNIQUES; COMPUTER SIMULATION; L-LACTATE DEHYDROGENASE; METAL NANOPARTICLES; PARTICLE SIZE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS; TITANIUM; ZIRCONIUM;

EID: 78349253077     PISSN: 02724332     EISSN: 15396924     Source Type: Journal    
DOI: 10.1111/j.1539-6924.2010.01438.x     Document Type: Article

References (44)

1. Puzyn T, Leszczynska D, Leszczynski J. Toward the development of ''Nano-QSARs'': Advances and challenges. Small, 2009; 5(22):2494-2509.
2. Jeng HA, Swanson J. Toxicity of metal oxide nanoparticles in mammalian cells. Journal of Environmental Science and Health Part A-Toxic/Hazardous Substances and Environmental Engineering, 2006; 41(12):2699-2711.
3. Hussain SM, Hess KL, Gearhart JM, Geiss KT, Schlager JJ. In vitro toxicity of nanoparticles in BRL 3A rat liver cells. Toxicology in Vitro, 2005; 19(7):975-983.
4. 2 particles: Evidence for differential responses. Toxicology, 2007; 230:90-104.
5. Sayes CM, Wahi R, Kurian PA, Liu YP, West JL, Ausman KD, Warheit DB, Colvin VL. Correlating nanoscale titania structure with toxicity: A cytotoxic and inflammatory response study with human dermal fibroblasts and human lung epithelial cells. Toxicological Sciences, 2006; 92(1):174-185.
6. 2 nanoparticles. International Journal of Nanotechnology, 2008; 5(1):15-29.
7. 2 particles: Evidence for differential responses. Toxicology, 2007; 230:90-104.
8. 2 rods and dots in rats: Toxicity is not dependant upon particle size and surface area. Toxicological Sciences, 2006; 91(1):227-236.
9. 2 in heterogeneous photocatalysis for phenol oxidation in water. Journal of Physical Chemistry B, 2000; 104(19):4815-4820.
10. Schattka JH, Shchukin DG, Jia JG, Antonietti M, Caruso RA. Photocatalytic activities of porous titania and titania/zirconia structures formed by using a polymer gel templating. Chemistry of Materials, 2002; 14(12):5103-5108.
11. 2 using EPR. Journal of Physical Chemistry B, 2003; 107(19):4545-4549.
12. Monteiller C, Tran L, MacNee W, Faux S, Jones A, Miller B, Donaldosn K. The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: The role of surface area. Occupational and Environmental Medicine, 2007; 64(9):609-615.
13. Lian T, Ho RJY. Trends and developments in liposome drug delivery systems. Journal of Pharmaceutical Sciences, 2001; 90(6):667-680.
14. Zhu KW, Ng WK, Shen SC, Tan RBH, Heng PWS. Design of a device for simultaneous particle size and electrostatic charge measurement of inhalation drugs. Pharmaceutical Research, 2008; 25(11):2488-2496.
15. Ahsan FL, Rivas IP, Khan MA, Suarez AIT. Targeting to macrophages: Role of physicochemical properties of particulate carriers-liposomes and microspheres-on the phagocytosis by macrophages. Journal of Controlled Release, 2002; 79(1-3):S0168-3659.
16. Ferrara P, Gohlke H, Price DJ, Klebe G, Brooks CL. Assessing scoring functions for protein-ligand interactions. Journal of Medicinal Chemistry, 2004; 47(12):3032-3047.
17. Shoichet BK, Leach AR, Kuntz ID. Ligand solvation in molecular docking. Proteins-Structure Function and Genetics, 1999; 34(1):4-16.
18. Hernandez-Sierra JF, Ruiz F, Pena DCC, Martinez-Guitierrez F, Martinez AE, Guillen ADP, Tapia-Perez H, Castanon GM. The antimicrobial sensitivity of Streptococcus mutans to nanoparticles of silver, zinc oxide, and gold. Nanomedicine-Nanotechnology Biology and Medicine, 2008; 4(3):237-240.
19. Gojova A, Guo B, Kota RS, Rutledge JC, Kennedy IM, Barakat AI. Induction of inflammation in vascular endothelial cells by metal oxide nanoparticles: Effect of particle composition. Environmental Health Perspectives, 2007; 115(3):403-409.
20. Bagchi D, Bagchi M, Hassoun EA, Stohs SJ. In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides. Toxicology, 1995; 104(1-3):129-140.
21. Kirkland JB. Lipid peroxidation, protein thiol oxidation, and DNA damage in hydrogen peroxide-induced injury to endothelial cells: Role of activation of poly(ADP-ribose)polymerase. Biochimica Et Biophysica Acta, 1991; 1092(3):319-325.
22. Koizumi T, Shirakura H, Kumagai H, Tatsumoto H, Suzuki KT. Mechanism of cadmium-induced cytotoxicity in rat hepatocytes: Cadmium-induced active oxygen-related permeability changes of the plasma membrane. Toxicology, 1996; 114(2):125-134.
23. Tebbe B, Wu SL, Geilen CC, Eberle J, Kodelja V, Orfanos CE. L-ascorbic acid inhibits UVA-induced lipid peroxidation and secretion of IL-1 alpha and IL-6 in cultured human keratinocytes in vitro. Journal of Investigative Dermatology, 1997; 108(3):302-306.
24. Tarek M, Maigret B, Chipot C. Molecular dynamics investigation of an oriented cyclic peptide nanotube in DMPC bilayers. Biophysical Journal, 2003; 85:2287-2298.
25. Liu J, Hopfinger A. Identification of possible sources of nanotoxicity from carbon nanotubes inserted into membrane bilayers using membrane interaction quantitative structure-activity relationship analysis. Chemical Research in Toxicology, 2008; 21(2):459-466.
26. Lopez C, Nielsen S, Ensing B, Moore P, Klein M. Structure and dynamics of model pore insertion into a membrane. Biophysical Journal, 2005; 88:3083-3094.
27. Lopez C, Nielsen S, Moore P, Klein M. Understanding nature's design for a nanosyringe. Proceedings of the National Academy of Sciences of the United States of America, 2004; 101(13):4431-4434.
28. Sayes CM, Fortner JD, Guo W, Lyon DY, Boyd AM, Ausman KD, Tao YJ, Sitharaman B, Wilson LJ, Hughes JB, West JL, Colvin VL. The differential cytotoxicity of water-soluble fullerenes. Nano Letters, 2004; 4(10):1881-1887.
29. Sayes CM, Reed KL, Warheit DB. Assessing toxicity of fine and nanoparticles: Comparing in vitro measurements to in vivo pulmonary toxicity profiles. Toxicological Sciences, 2007; 97(1):163-180.
30. Devroye L, Gyorfi L, Lugosi G. A Probabilistic Theory of Pattern Recognition. New York Springer-Verlag, 1996.
31. Braga-Neto U, Dougherty E. Bolstered error estimation. Pattern Recognition, 2004; 37:1267-1281.
32. Zhao C, Ivanov I, Dougherty ER, Hartman T, Lanza E, Bobe G, Colburn N, Lupton J, Davidson L, Chapkin R. Non-invasive detection of candidate molecular biomarkers in subjects with a history of insulin resistance and colorectal adenomas. Cancer Prevention Research, 2009; 298(5):G582-G589.
33. Teeguarden JG, Hinderliter PM, Orr G, Thrall BD, Pounds JG. Particokinetics in vitro: Dosimetry considerations for in vitro nanoparticle toxicity assessments. Toxicological Sciences, 2007; 95(2):300-312.
34. Ge YQ, Zhang Y, Xia JG, Ma M, He SY, Nie F, Gu N. Effect of surface charge and agglomerate degree of magnetic iron oxide nanoparticles on KB cellular uptake in vitro. Colloids and Surfaces B-Biointerfaces, 2009; 73(2):294-301.
35. 2 aerosol nanoparticle reactor for occupational health and safety studies. Journal of Occupational and Environmental Hygiene, 2008; 5(6):390-398.
36. Jiang JK, Oberdorster G, Biswas P. Characterization of size, surface charge, and agglomeration state of nanoparticle dispersions for toxicological studies (translated from English). Journal of Nanoparticle Research, 2009; 11(1):77-89 (in English).
37. Warheit D, Webb T, Colvin V, Reed K, Sayes CM. Pulmonary bioassay studies with nanoscale and fine-quartz particles in rats: Toxicity is not dependent upon particle size but on surface characteristics. Toxicological Sciences, 2007; 95(1):270-280.
38. Dobrovolskaia MA, Aggarwal P, Hall JB, McNeil SE. Preclinical studies to understand nanoparticle interaction with the immune system and its potential effects on nanoparticle biodistribution. Molecular Pharmaceutics, 2008; 5(4):487-495.
39. Handy RD, Owen R, Valsami-Jones E. The ecotoxicology of nanoparticles and nanomaterials: Current status, knowledge gaps, challenges, and future needs. Ecotoxicology, 2008; 17(5):315-325.
40. Hardman R. A toxicologic review of quantum dots: Toxicity depends on physicochemical and environmental factors. Environmental Health Perspectives, 2006; 114(2):165-172.
41. Li SD, Huang L. Pharmacokinetics and biodistribution of nanoparticles. Molecular Pharmaceutics, 2008; 5(4):496-504.
42. Lockman PR, Koziara JM, Mumper RJ, Allen DD. Nanoparticle surface charges alter blood-brain barrier integrity and permeability. Journal of Drug Targeting, 2004; 12(9-10):635-641.
43. Murdock RC, Braydich-Stolle L, Schrand AM, Schlager JJ, Hussain SM. Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique. Toxicological Sciences, 2008; 101(2):239-253.
44. Berg JM, Romoser A, Banerjee N, Zebda R, Sayes CM. The relationship between pH and zeta potential of 30 nm metal oxide nanoparticle suspensions relevant to in vitro toxicological evaluations. Nanotoxicology, 2009; 3(4):276-283.