메뉴 건너뛰기




Volumn 34, Issue 2, 2010, Pages 71-79

In vitro effects of 2-methoxyestradiol-bis-sulphamate on cell growth, morphology and cell cycle dynamics in the MCF-7 breast adenocarcinoma cell line

Author keywords

2 methoxyestradiol; Apoptosis; Autophagy; Cancer; Estradiol derivative; Sulphamoylated

Indexed keywords

2 METHOXYESTRADIOL; 2 METHOXYESTRADIOL DISULFAMATE; CYCLIN B1; UNCLASSIFIED DRUG; 2 METHOXYESTRIOL; 2-METHOXYESTRIOL; DRUG DERIVATIVE; ESTRIOL;

EID: 78349241729     PISSN: 03279545     EISSN: 16675746     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (13)

References (22)
  • 2
    • 22144493866 scopus 로고    scopus 로고
    • Negative and positive regulation of HIF-1: A complex network
    • Bàrdos J, Ashcroft M (2005). Negative and positive regulation of HIF-1: A complex network. Biochimica et Biophysica Acta 1755: 107-120.
    • (2005) Biochimica Et Biophysica Acta , vol.1755 , pp. 107-120
    • Ashcroft, M.1
  • 4
    • 48149110838 scopus 로고    scopus 로고
    • 2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo technique
    • Foster P, Ho Y, Newman S, Kasprzyk P, Leese M, Potter B (2008). 2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo technique. Breast Cancer Research and Treatment 111: 251-260.
    • (2008) Breast Cancer Research and Treatment , vol.111 , pp. 251-260
    • Foster, P.1    Ho, Y.2    Newman, S.3    Kasprzyk, P.4    Leese, M.5    Potter, B.6
  • 7
    • 0141987905 scopus 로고    scopus 로고
    • The effects of 2-methoxy oestrogens and their sulphamoylated derivatives in conjunction with TNF-alpha on endothelial and fibroblast cell growth, morphology and apoptosis
    • Ho Y, Newman S, Purohit A, Leese M, Potter B, Reed M (2003). The effects of 2-methoxy oestrogens and their sulphamoylated derivatives in conjunction with TNF-alpha on endothelial and fibroblast cell growth, morphology and apoptosis. Journal of Steroid Biochemistry and Molecular Biology 86: 189-196.
    • (2003) Journal of Steroid Biochemistry and Molecular Biology , vol.86 , pp. 189-196
    • Ho, Y.1    Newman, S.2    Purohit, A.3    Leese, M.4    Potter, B.5    Reed, M.6
  • 8
    • 1642319678 scopus 로고    scopus 로고
    • Pharmacokinetics and efficacy of 2-Methoxyoestradiol and 2-Methoxyoestradiol-bis-sulphamate in vivo in rodents
    • Ireson C, Chander S, Purohit A, Perera S, Newman S, Parish D (2004). Pharmacokinetics and efficacy of 2-Methoxyoestradiol and 2-methoxyoestradiol-bis-sulphamate in vivo in rodents. British Journal of Cancer 90: 932-937.
    • (2004) British Journal of Cancer , vol.90 , pp. 932-937
    • Ireson, C.1    Chander, S.2    Purohit, A.3    Perera, S.4    Newman, S.5    Parish, D.6
  • 9
    • 33750483598 scopus 로고    scopus 로고
    • Phase I safety, pharmacokinetic and pharmacodynamic studies of 2-methoxyestradiol alone or in combination with docetaxel in patients with locally recurrent or metastatic breast cancer
    • James J, Murry D, Treston A, Storniolo A, Sledge G, Sidor C (2006). Phase I safety, pharmacokinetic and pharmacodynamic studies of 2-methoxyestradiol alone or in combination with docetaxel in patients with locally recurrent or metastatic breast cancer. Investigational New Drugs 25: 41-48.
    • (2006) Investigational New Drugs , vol.25 , pp. 41-48
    • James, J.1    Murry, D.2    Treston, A.3    Storniolo, A.4    Sledge, G.5    Sidor, C.6
  • 10
    • 0031015504 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol
    • Klauber N, Parangi S, Flynn E, Hamel E, D'Amato R (1997). Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol. Cancer Research 57: 81-86.
    • (1997) Cancer Research , vol.57 , pp. 81-86
    • Klauber, N.1    Parangi, S.2    Flynn, E.3    Hamel, E.4    D'Amato, R.5
  • 11
    • 0037320432 scopus 로고    scopus 로고
    • 2-Methoxyestradiol, a promising anticancer agent
    • Lakhani N, Sarkar M, Venitz J, Figg W (2003). 2-Methoxyestradiol, a promising anticancer agent. Pharmacotherapy 23: 165-172.
    • (2003) Pharmacotherapy , vol.23 , pp. 165-172
    • Lakhani, N.1    Sarkar, M.2    Venitz, J.3    Figg, W.4
  • 12
    • 0842269204 scopus 로고    scopus 로고
    • Mechanism of action of 2-methoxyestradiol: New developments
    • Mooberry S (2003a). Mechanism of action of 2-methoxyestradiol: new developments. Drug Resistance Updates 6: 355-361.
    • (2003) Drug Resistance Updates , vol.6 , pp. 355-361
    • Mooberry, S.1
  • 13
    • 0742269867 scopus 로고    scopus 로고
    • New insights into 2-methoxyestradiol, a promising antiangiogenic and antitumor agent
    • Mooberry S (2003b). New insights into 2-methoxyestradiol, a promising antiangiogenic and antitumor agent. Current Opinion in Oncology 15: 425-430.
    • (2003) Current Opinion in Oncology , vol.15 , pp. 425-430
    • Mooberry, S.1
  • 14
    • 0029880479 scopus 로고    scopus 로고
    • The endogenous estrogen metabolite 2-methoxyestradiol induces apoptotic neuronal cell death in vitro
    • Nakagawa-Yagi Y, Ogane N, Inoki Y, Kitoh N (1996). The endogenous estrogen metabolite 2-methoxyestradiol induces apoptotic neuronal cell death in vitro. Life Sciences 58: 1461-1467.
    • (1996) Life Sciences , vol.58 , pp. 1461-1467
    • Nakagawa-Yagi, Y.1    Ogane, N.2    Inoki, Y.3    Kitoh, N.4
  • 15
    • 0031947952 scopus 로고    scopus 로고
    • The development of A-ring modified analogues of oestrone-3-O-sulphamate as potent steroid sulphatase inhibitors with reduced oestrogenicity
    • Purohit A, Vernon K, Wagenaar Hummelinck A, Woo L, Hejaz H, Potter B (1998). The development of A-ring modified analogues of oestrone-3-O-sulphamate as potent steroid sulphatase inhibitors with reduced oestrogenicity. Journal of Steroid Biochemistry and Molecular Biology 64: 269-275.
    • (1998) Journal of Steroid Biochemistry and Molecular Biology , vol.64 , pp. 269-275
    • Purohit, A.1    Vernon, K.2    Hummelinck, W.A.3    Woo, L.4    Hejaz, H.5    Potter, B.6
  • 19
    • 34447106558 scopus 로고    scopus 로고
    • 2-Methoxyestradiol-a unique blend of activities generating a new class of anti-tumour anti-inflammatory agents
    • Sutherland T, Anderson R, Hughes R, Altmann E, Schuliga M, Ziogas J (2007). 2-Methoxyestradiol-a unique blend of activities generating a new class of anti-tumour/anti-inflammatory agents. Drug Discovery Today 12: 577-584.
    • (2007) Drug Discovery Today , vol.12 , pp. 577-584
    • Sutherland, T.1    Anderson, R.2    Hughes, R.3    Altmann, E.4    Schuliga, M.5    Ziogas, J.6
  • 20
    • 0037319954 scopus 로고    scopus 로고
    • Growth inhibition of multi-drug-resistant breast cancer cells by 2-methoxyoestradiol-bis-sulphamate and 2-ethyloestradiolbis-sulphamate
    • Suzuki R, Newman S, Purohit A, Leese M, Potter B, Reed M (2003). Growth inhibition of multi-drug-resistant breast cancer cells by 2-methoxyoestradiol-bis-sulphamate and 2-ethyloestradiolbis-sulphamate. Journal of Steroid Biochemistry & Molecular Biology 84: 269-278.
    • (2003) Journal of Steroid Biochemistry & Molecular Biology , vol.84 , pp. 269-278
    • Suzuki, R.1    Newman, S.2    Purohit, A.3    Leese, M.4    Potter, B.5    Reed, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.