-
2
-
-
22144493866
-
Negative and positive regulation of HIF-1: A complex network
-
Bàrdos J, Ashcroft M (2005). Negative and positive regulation of HIF-1: A complex network. Biochimica et Biophysica Acta 1755: 107-120.
-
(2005)
Biochimica Et Biophysica Acta
, vol.1755
, pp. 107-120
-
-
Ashcroft, M.1
-
3
-
-
34247604099
-
In vivo inhibition of angiogenesis by sulphamoylated derivatives of 2-methoxyoestradiol
-
Chander S, Foster P, Leese M, Newman S, Potter B, Purohit A (2007). In vivo inhibition of angiogenesis by sulphamoylated derivatives of 2-methoxyoestradiol. British Journal of Cancer 96: 1368 -1376.
-
(2007)
British Journal of Cancer
, vol.96
, pp. 1368-1376
-
-
Chander, S.1
Foster, P.2
Leese, M.3
Newman, S.4
Potter, B.5
Purohit, A.6
-
4
-
-
48149110838
-
2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo technique
-
Foster P, Ho Y, Newman S, Kasprzyk P, Leese M, Potter B (2008). 2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo technique. Breast Cancer Research and Treatment 111: 251-260.
-
(2008)
Breast Cancer Research and Treatment
, vol.111
, pp. 251-260
-
-
Foster, P.1
Ho, Y.2
Newman, S.3
Kasprzyk, P.4
Leese, M.5
Potter, B.6
-
7
-
-
0141987905
-
The effects of 2-methoxy oestrogens and their sulphamoylated derivatives in conjunction with TNF-alpha on endothelial and fibroblast cell growth, morphology and apoptosis
-
Ho Y, Newman S, Purohit A, Leese M, Potter B, Reed M (2003). The effects of 2-methoxy oestrogens and their sulphamoylated derivatives in conjunction with TNF-alpha on endothelial and fibroblast cell growth, morphology and apoptosis. Journal of Steroid Biochemistry and Molecular Biology 86: 189-196.
-
(2003)
Journal of Steroid Biochemistry and Molecular Biology
, vol.86
, pp. 189-196
-
-
Ho, Y.1
Newman, S.2
Purohit, A.3
Leese, M.4
Potter, B.5
Reed, M.6
-
8
-
-
1642319678
-
Pharmacokinetics and efficacy of 2-Methoxyoestradiol and 2-Methoxyoestradiol-bis-sulphamate in vivo in rodents
-
Ireson C, Chander S, Purohit A, Perera S, Newman S, Parish D (2004). Pharmacokinetics and efficacy of 2-Methoxyoestradiol and 2-methoxyoestradiol-bis-sulphamate in vivo in rodents. British Journal of Cancer 90: 932-937.
-
(2004)
British Journal of Cancer
, vol.90
, pp. 932-937
-
-
Ireson, C.1
Chander, S.2
Purohit, A.3
Perera, S.4
Newman, S.5
Parish, D.6
-
9
-
-
33750483598
-
Phase I safety, pharmacokinetic and pharmacodynamic studies of 2-methoxyestradiol alone or in combination with docetaxel in patients with locally recurrent or metastatic breast cancer
-
James J, Murry D, Treston A, Storniolo A, Sledge G, Sidor C (2006). Phase I safety, pharmacokinetic and pharmacodynamic studies of 2-methoxyestradiol alone or in combination with docetaxel in patients with locally recurrent or metastatic breast cancer. Investigational New Drugs 25: 41-48.
-
(2006)
Investigational New Drugs
, vol.25
, pp. 41-48
-
-
James, J.1
Murry, D.2
Treston, A.3
Storniolo, A.4
Sledge, G.5
Sidor, C.6
-
10
-
-
0031015504
-
Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol
-
Klauber N, Parangi S, Flynn E, Hamel E, D'Amato R (1997). Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol. Cancer Research 57: 81-86.
-
(1997)
Cancer Research
, vol.57
, pp. 81-86
-
-
Klauber, N.1
Parangi, S.2
Flynn, E.3
Hamel, E.4
D'Amato, R.5
-
11
-
-
0037320432
-
2-Methoxyestradiol, a promising anticancer agent
-
Lakhani N, Sarkar M, Venitz J, Figg W (2003). 2-Methoxyestradiol, a promising anticancer agent. Pharmacotherapy 23: 165-172.
-
(2003)
Pharmacotherapy
, vol.23
, pp. 165-172
-
-
Lakhani, N.1
Sarkar, M.2
Venitz, J.3
Figg, W.4
-
12
-
-
0842269204
-
Mechanism of action of 2-methoxyestradiol: New developments
-
Mooberry S (2003a). Mechanism of action of 2-methoxyestradiol: new developments. Drug Resistance Updates 6: 355-361.
-
(2003)
Drug Resistance Updates
, vol.6
, pp. 355-361
-
-
Mooberry, S.1
-
13
-
-
0742269867
-
New insights into 2-methoxyestradiol, a promising antiangiogenic and antitumor agent
-
Mooberry S (2003b). New insights into 2-methoxyestradiol, a promising antiangiogenic and antitumor agent. Current Opinion in Oncology 15: 425-430.
-
(2003)
Current Opinion in Oncology
, vol.15
, pp. 425-430
-
-
Mooberry, S.1
-
14
-
-
0029880479
-
The endogenous estrogen metabolite 2-methoxyestradiol induces apoptotic neuronal cell death in vitro
-
Nakagawa-Yagi Y, Ogane N, Inoki Y, Kitoh N (1996). The endogenous estrogen metabolite 2-methoxyestradiol induces apoptotic neuronal cell death in vitro. Life Sciences 58: 1461-1467.
-
(1996)
Life Sciences
, vol.58
, pp. 1461-1467
-
-
Nakagawa-Yagi, Y.1
Ogane, N.2
Inoki, Y.3
Kitoh, N.4
-
15
-
-
0031947952
-
The development of A-ring modified analogues of oestrone-3-O-sulphamate as potent steroid sulphatase inhibitors with reduced oestrogenicity
-
Purohit A, Vernon K, Wagenaar Hummelinck A, Woo L, Hejaz H, Potter B (1998). The development of A-ring modified analogues of oestrone-3-O-sulphamate as potent steroid sulphatase inhibitors with reduced oestrogenicity. Journal of Steroid Biochemistry and Molecular Biology 64: 269-275.
-
(1998)
Journal of Steroid Biochemistry and Molecular Biology
, vol.64
, pp. 269-275
-
-
Purohit, A.1
Vernon, K.2
Hummelinck, W.A.3
Woo, L.4
Hejaz, H.5
Potter, B.6
-
16
-
-
10744224981
-
Steroid sulphatase inhibitors for breast cancer therapy
-
Purohit A, Woo L, Chander S, Newman S, Ireson C, Ho Y (2003). Steroid sulphatase inhibitors for breast cancer therapy. Journal of Steroid Biochemistry and Molecular Biology 86: 423-432.
-
(2003)
Journal of Steroid Biochemistry and Molecular Biology
, vol.86
, pp. 423-432
-
-
Purohit, A.1
Woo, L.2
Chander, S.3
Newman, S.4
Ireson, C.5
Ho, Y.6
-
17
-
-
0037321793
-
Inhibition of MCF-7 breast cancer cell proliferation and in vivo steroid sulphatase activity by 2-methoxyoestradiolbis-sulphamate
-
Raobaikady B, Purohit A, Chander S, Woo L, Leese M, Potter B (2003). Inhibition of MCF-7 breast cancer cell proliferation and in vivo steroid sulphatase activity by 2-methoxyoestradiolbis-sulphamate. Journal of Steroid Biochemistry and Molecular Biology 84: 351-358.
-
(2003)
Journal of Steroid Biochemistry and Molecular Biology
, vol.84
, pp. 351-358
-
-
Raobaikady, B.1
Purohit, A.2
Chander, S.3
Woo, L.4
Leese, M.5
Potter, B.6
-
19
-
-
34447106558
-
2-Methoxyestradiol-a unique blend of activities generating a new class of anti-tumour anti-inflammatory agents
-
Sutherland T, Anderson R, Hughes R, Altmann E, Schuliga M, Ziogas J (2007). 2-Methoxyestradiol-a unique blend of activities generating a new class of anti-tumour/anti-inflammatory agents. Drug Discovery Today 12: 577-584.
-
(2007)
Drug Discovery Today
, vol.12
, pp. 577-584
-
-
Sutherland, T.1
Anderson, R.2
Hughes, R.3
Altmann, E.4
Schuliga, M.5
Ziogas, J.6
-
20
-
-
0037319954
-
Growth inhibition of multi-drug-resistant breast cancer cells by 2-methoxyoestradiol-bis-sulphamate and 2-ethyloestradiolbis-sulphamate
-
Suzuki R, Newman S, Purohit A, Leese M, Potter B, Reed M (2003). Growth inhibition of multi-drug-resistant breast cancer cells by 2-methoxyoestradiol-bis-sulphamate and 2-ethyloestradiolbis-sulphamate. Journal of Steroid Biochemistry & Molecular Biology 84: 269-278.
-
(2003)
Journal of Steroid Biochemistry & Molecular Biology
, vol.84
, pp. 269-278
-
-
Suzuki, R.1
Newman, S.2
Purohit, A.3
Leese, M.4
Potter, B.5
Reed, M.6
-
21
-
-
18144409797
-
The effects of 2-Methoxyoestrogen sulphamates on the in vitro and in vivo proliferation of breast cancer cells
-
Utsumi T, Leese M, Chander S, Gaukroger K, Purohit A, Newman S (2005). The effects of 2-methoxyoestrogen sulphamates on the in vitro and in vivo proliferation of breast cancer cells. Journal of Steroid Biochemistry & Molecular Biology 94: 219-227.
-
(2005)
Journal of Steroid Biochemistry & Molecular Biology
, vol.94
, pp. 219-227
-
-
Utsumi, T.1
Leese, M.2
Chander, S.3
Gaukroger, K.4
Purohit, A.5
Newman, S.6
-
22
-
-
0034713747
-
2-Methoxyestradiol, an endogenous estrogen metabolite, induces thyroid cell apoptosis
-
Wang H, Myc A, Koenig R, Bretz J, Arscott P, Baker J (2000). 2-Methoxyestradiol, an endogenous estrogen metabolite, induces thyroid cell apoptosis. Molecular and Cellular Endocrinology 165: 163-172.
-
(2000)
Molecular and Cellular Endocrinology
, vol.165
, pp. 163-172
-
-
Wang, H.1
Myc, A.2
Koenig, R.3
Bretz, J.4
Arscott, P.5
Baker, J.6
|