메뉴 건너뛰기




Volumn 185, Issue 3, 2010, Pages 939-959

Surprising fitness consequences of GC-biased gene conversion: I. Mutation load and inbreeding depression

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYSTEINE; GLYCINE;

EID: 78349237426     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.110.116368     Document Type: Article
Times cited : (42)

References (88)
  • 2
    • 0034054671 scopus 로고    scopus 로고
    • Inbreeding depression due to mildly deleterious mutations in finite populations: Size does matter
    • Bataillon, T., and M. Kirkpatrick, 2000 Inbreeding depression due to mildly deleterious mutations in finite populations: size does matter. Genet. Res. 75: 75-81.
    • (2000) Genet. Res. , vol.75 , pp. 75-81
    • Bataillon, T.1    Kirkpatrick, M.2
  • 3
    • 0025074843 scopus 로고
    • The effect of biased conversion on the mutation load
    • Bengtsson, B. O., 1990 The effect of biased conversion on the mutation load. Genet. Res. 55: 183-187.
    • (1990) Genet. Res. , vol.55 , pp. 183-187
    • Bengtsson, B.O.1
  • 4
    • 0025502227 scopus 로고
    • Evolution of the segregation ratio: Modification of gene conversion and meiotic drive
    • Bengtsson, B. O., and M. K. Uyenoyama, 1990 Evolution of the segregation ratio: modification of gene conversion and meiotic drive. Theor. Popul. Biol. 38: 192-218.
    • (1990) Theor. Popul. Biol. , vol.38 , pp. 192-218
    • Bengtsson, B.O.1    Uyenoyama, M.K.2
  • 5
    • 58849161775 scopus 로고    scopus 로고
    • Hotspots of biased nucleotide substitutions in human genes
    • Berglund, J., K. S. Pollard and M. T. Webster, 2009 Hotspots of biased nucleotide substitutions in human genes. PLoS Biol. 7: e26.
    • (2009) PLoS Biol. , vol.7
    • Berglund, J.1    Pollard, K.S.2    Webster, M.T.3
  • 6
    • 0035986891 scopus 로고    scopus 로고
    • Integrating genomics, bioinformatics, and classical genetics to study the effects of recombination on genome evolution
    • Birdsell, J. A., 2002 Integrating genomics, bioinformatics, and classical genetics to study the effects of recombination on genome evolution. Mol. Biol. Evol. 19: 1181-1197.
    • (2002) Mol. Biol. Evol. , vol.19 , pp. 1181-1197
    • Birdsell, J.A.1
  • 7
    • 0023651289 scopus 로고
    • A specific mismatch repair event protects mammalian cells from loss of 5-methylcytosine
    • Brown, T. C., and J. Jiricny, 1987 A specific mismatch repair event protects mammalian cells from loss of 5-methylcytosine. Cell 50: 945-950.
    • (1987) Cell , vol.50 , pp. 945-950
    • Brown, T.C.1    Jiricny, J.2
  • 8
    • 0025941139 scopus 로고
    • The selection-mutation-drift theory of synonymous codon usage
    • Bulmer, M., 1991 The selection-mutation-drift theory of synonymous codon usage. Genetics 129: 897-907.
    • (1991) Genetics , vol.129 , pp. 897-907
    • Bulmer, M.1
  • 9
    • 0026691260 scopus 로고
    • Effects of partial inbreeding on fixation rates and variation of mutant genes
    • Caballero, A., and W. G. Hill, 1992 Effects of partial inbreeding on fixation rates and variation of mutant genes. Genetics 131: 493-507.
    • (1992) Genetics , vol.131 , pp. 493-507
    • Caballero, A.1    Hill, W.G.2
  • 10
    • 0026565824 scopus 로고
    • Evolutionary rates in partially self-fertilizing species
    • Charlesworth, B., 1992 Evolutionary rates in partially self-fertilizing species. Am. Nat. 140: 126-148.
    • (1992) Am. Nat. , vol.140 , pp. 126-148
    • Charlesworth, B.1
  • 11
    • 7344230525 scopus 로고    scopus 로고
    • Some evolutionary consequences of deleterious mutations
    • Charlesworth, B., and D. Charlesworth, 1998 Some evolutionary consequences of deleterious mutations. Genetica 102/103: 3-19.
    • (1998) Genetica , vol.102-103 , pp. 3-19
    • Charlesworth, B.1    Charlesworth, D.2
  • 12
    • 0027305597 scopus 로고
    • The effect of deleterious mutations on neutral molecular variation
    • Charlesworth, B., M. T. Morgan and D. Charlesworth, 1993 The effect of deleterious mutations on neutral molecular variation. Genetics 134: 1289-1303.
    • (1993) Genetics , vol.134 , pp. 1289-1303
    • Charlesworth, B.1    Morgan, M.T.2    Charlesworth, D.3
  • 13
    • 33646484211 scopus 로고    scopus 로고
    • Balancing selection and its effects on sequences in nearby genome regions
    • Charlesworth, D., 2006a Balancing selection and its effects on sequences in nearby genome regions. PLoS Genet. 2: e64.
    • (2006) PLoS Genet. , vol.2
    • Charlesworth, D.1
  • 14
    • 33750632708 scopus 로고    scopus 로고
    • Evolution of plant breeding systems
    • Charlesworth, D., 2006b Evolution of plant breeding systems. Curr. Biol. 16: R726-R735.
    • (2006) Curr. Biol. , vol.16
    • Charlesworth, D.1
  • 15
    • 0023468755 scopus 로고
    • Inbreeding depression and its evolutionary consequences
    • Charlesworth, D., and B. Charlesworth, 1987 Inbreeding depression and its evolutionary consequences. Annu. Rev. Ecol. Syst. 18: 237-268.
    • (1987) Annu. Rev. Ecol. Syst. , vol.18 , pp. 237-268
    • Charlesworth, D.1    Charlesworth, B.2
  • 16
    • 0000343315 scopus 로고
    • Inbreeding depression with heterozygote advantage and its effect on selection for modifiers changing the outcrossing rate
    • Charlesworth, D., and B. Charlesworth, 1990 Inbreeding depression with heterozygote advantage and its effect on selection for modifiers changing the outcrossing rate. Evolution 44: 1469-1489.
    • (1990) Evolution , vol.44 , pp. 1469-1489
    • Charlesworth, D.1    Charlesworth, B.2
  • 17
    • 70350048798 scopus 로고    scopus 로고
    • The genetics of inbreeding depression
    • Charlesworth, D., and J. H. Willis, 2009 The genetics of inbreeding depression. Nat. Rev. Genet. 10: 783-796.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 783-796
    • Charlesworth, D.1    Willis, J.H.2
  • 18
    • 39449116116 scopus 로고    scopus 로고
    • High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans
    • Coop, G., X. Wen, C. Ober, J. K. Pritchard and M. Przeworski, 2008 High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans. Science 319: 1395-1398.
    • (2008) Science , vol.319 , pp. 1395-1398
    • Coop, G.1    Wen, X.2    Ober, C.3    Pritchard, J.K.4    Przeworski, M.5
  • 19
    • 0002995790 scopus 로고
    • Mutation, mean fitness, and genetic load
    • edited by D. Futuyma and J. Antonovics. Oxford University Press, Oxford
    • Crow, J. F., 1993 Mutation, mean fitness, and genetic load, pp. 3-42 in Oxford Surveys in Evolutionary Biology, Vol. 9, edited by D. Futuyma and J. Antonovics. Oxford University Press, Oxford.
    • (1993) Oxford Surveys in Evolutionary Biology , vol.9 , pp. 3-42
    • Crow, J.F.1
  • 20
    • 44949198268 scopus 로고    scopus 로고
    • The impact of recombination on nucleotide substitutions in the human genome
    • Duret, L., and P. F. Arndt, 2008 The impact of recombination on nucleotide substitutions in the human genome. PLoS Genet. 4: e1000071.
    • (2008) PLoS Genet. , vol.4
    • Duret, L.1    Arndt, P.F.2
  • 21
    • 70350236484 scopus 로고    scopus 로고
    • Biased gene conversion and the evolution of mammalian genomic landscapes
    • Duret, L., and N. Galtier, 2009a Biased gene conversion and the evolution of mammalian genomic landscapes. Annu. Rev. Genomics Hum. Genet. 10: 285-311.
    • (2009) Annu. Rev. Genomics Hum. Genet. , vol.10 , pp. 285-311
    • Duret, L.1    Galtier, N.2
  • 22
    • 59849095985 scopus 로고    scopus 로고
    • Comment on "Human-specific gain of function in a developmental enhancer"
    • (author reply: 714)
    • Duret, L., and N. Galtier, 2009b Comment on "Human-specific gain of function in a developmental enhancer". Science 323: 714 (author reply: 714).
    • (2009) Science , vol.323 , pp. 714
    • Duret, L.1    Galtier, N.2
  • 23
    • 0033551151 scopus 로고    scopus 로고
    • Expression pattern and, surprisingly, gene length shape codon usage in Caenorhabditis, Drosophila, Arabidopsis
    • Duret, L., and D. Mouchiroud, 1999 Expression pattern and, surprisingly, gene length shape codon usage in Caenorhabditis, Drosophila, Arabidopsis. Proc. Natl. Acad. Sci. USA 96: 4482-4487.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4482-4487
    • Duret, L.1    Mouchiroud, D.2
  • 24
    • 33751511707 scopus 로고    scopus 로고
    • A new perspective on isochore evolution
    • Duret, L., A. Eyre-Walker and N. Galtier, 2006 A new perspective on isochore evolution. Gene 385: 71-74.
    • (2006) Gene , vol.385 , pp. 71-74
    • Duret, L.1    Eyre-Walker, A.2    Galtier, N.3
  • 25
    • 41649113803 scopus 로고    scopus 로고
    • Analysis of sequence variability in the macronuclear DNA of Paramecium tetraurelia: A somatic view of the germline
    • Duret, L., J. Cohen, C. Jubin, P. Dessen, J. F. Gout et al., 2008 Analysis of sequence variability in the macronuclear DNA of Paramecium tetraurelia: a somatic view of the germline. Genome Res. 18: 585-596.
    • (2008) Genome Res. , vol.18 , pp. 585-596
    • Duret, L.1    Cohen, J.2    Jubin, C.3    Dessen, P.4    Gout, J.F.5
  • 26
    • 72649102150 scopus 로고    scopus 로고
    • Distributions of selectively constrained sites and deleterious mutation rates in the hominid and murid genomes
    • Eory, L., D. L. Halligan and P. D. Keightley, 2010 Distributions of selectively constrained sites and deleterious mutation rates in the hominid and murid genomes. Mol. Biol. Evol. 27: 177-192.
    • (2010) Mol. Biol. Evol. , vol.27 , pp. 177-192
    • Eory, L.1    Halligan, D.L.2    Keightley, P.D.3
  • 28
    • 33745347447 scopus 로고    scopus 로고
    • The distribution of fitness effects of new deleterious amino acid mutations in humans
    • Eyre-Walker, A., M. Woolfit and T. Phelps, 2006 The distribution of fitness effects of new deleterious amino acid mutations in humans. Genetics 173: 891-900.
    • (2006) Genetics , vol.173 , pp. 891-900
    • Eyre-Walker, A.1    Woolfit, M.2    Phelps, T.3
  • 29
    • 34248641119 scopus 로고    scopus 로고
    • Adaptation or biased gene conversion? Extending the null hypothesis of molecular evolution
    • Galtier, N., and L. Duret, 2007 Adaptation or biased gene conversion? Extending the null hypothesis of molecular evolution. Trends Genet. 23: 273-277.
    • (2007) Trends Genet. , vol.23 , pp. 273-277
    • Galtier, N.1    Duret, L.2
  • 30
    • 0034766004 scopus 로고    scopus 로고
    • GC-content evolution in mammalian genomes: The biased gene conversion hypothesis
    • Galtier, N., G. Piganeau, D. Mouchiroud and L. Duret, 2001 GC-content evolution in mammalian genomes: the biased gene conversion hypothesis. Genetics 159: 907-911.
    • (2001) Genetics , vol.159 , pp. 907-911
    • Galtier, N.1    Piganeau, G.2    Mouchiroud, D.3    Duret, L.4
  • 31
    • 33644780844 scopus 로고    scopus 로고
    • GC-biased segregation of noncoding polymorphisms in Drosophila
    • Galtier, N., E. Bazin and N. Bierne, 2006 GC-biased segregation of noncoding polymorphisms in Drosophila. Genetics 172: 221-228.
    • (2006) Genetics , vol.172 , pp. 221-228
    • Galtier, N.1    Bazin, E.2    Bierne, N.3
  • 32
    • 58149328496 scopus 로고    scopus 로고
    • GC-biased gene conversion promotes the fixation of deleterious amino acid changes in primates
    • Galtier, N., L. Duret, S. Glémin and V. Ranwez, 2009 GC-biased gene conversion promotes the fixation of deleterious amino acid changes in primates. Trends Genet. 25: 1-5.
    • (2009) Trends Genet. , vol.25 , pp. 1-5
    • Galtier, N.1    Duret, L.2    Glémin, S.3    Ranwez, V.4
  • 33
    • 0347135854 scopus 로고    scopus 로고
    • How are deleterious mutations purged? Drift versus nonrandom mating
    • Glémin, S., 2003 How are deleterious mutations purged? Drift versus nonrandom mating. Evolution 57: 2678-2687.
    • (2003) Evolution , vol.57 , pp. 2678-2687
    • Glémin, S.1
  • 34
    • 35549007506 scopus 로고    scopus 로고
    • Mating systems and the efficacy of selection at the molecular level
    • Glémin, S., 2007 Mating systems and the efficacy of selection at the molecular level. Genetics 177: 905-916.
    • (2007) Genetics , vol.177 , pp. 905-916
    • Glémin, S.1
  • 35
    • 17944396797 scopus 로고    scopus 로고
    • Patterns of inbreeding depression and architecture of the load in subdivided populations
    • Glémin, S., J. Ronfort and T. Bataillon, 2003 Patterns of inbreeding depression and architecture of the load in subdivided populations. Genetics 165: 2193-2212.
    • (2003) Genetics , vol.165 , pp. 2193-2212
    • Glémin, S.1    Ronfort, J.2    Bataillon, T.3
  • 36
    • 34247214027 scopus 로고    scopus 로고
    • Impact of mating systems on patterns of sequence polymorphism in flowering plants
    • Glémin, S., E. Bazin and D. Charlesworth, 2006 Impact of mating systems on patterns of sequence polymorphism in flowering plants. Proc. Biol. Sci. 273: 3011-3019.
    • (2006) Proc. Biol. Sci. , vol.273 , pp. 3011-3019
    • Glémin, S.1    Bazin, E.2    Charlesworth, D.3
  • 37
    • 0017137106 scopus 로고
    • Gene conversion: A hitherto overlooked parameter in population genetics
    • Gutz, H., and J. F. Leslie, 1976 Gene conversion: a hitherto overlooked parameter in population genetics. Genetics 83: 861-866.
    • (1976) Genetics , vol.83 , pp. 861-866
    • Gutz, H.1    Leslie, J.F.2
  • 38
    • 0001400708 scopus 로고
    • The effect of variation on fitness
    • Haldane, J. B. S., 1937 The effect of variation on fitness. Am. Nat. 71: 337-349.
    • (1937) Am. Nat. , vol.71 , pp. 337-349
    • Haldane, J.B.S.1
  • 39
    • 39749201582 scopus 로고    scopus 로고
    • Mating system and recombination affect molecular evolution in four Triticeae species
    • Haudry, A., A. Cenci, C. Guilhaumon, E. Paux, S. Poirier et al., 2008 Mating system and recombination affect molecular evolution in four Triticeae species. Genet. Res. 90: 97-109.
    • (2008) Genet. Res. , vol.90 , pp. 97-109
    • Haudry, A.1    Cenci, A.2    Guilhaumon, C.3    Paux, E.4    Poirier, S.5
  • 40
    • 10644283823 scopus 로고    scopus 로고
    • Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution
    • International Chicken Genome Sequencing Consortium
    • International Chicken Genome Sequencing Consortium, 2004 Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature 432: 695-716.
    • (2004) Nature , vol.432 , pp. 695-716
  • 41
    • 54149103332 scopus 로고    scopus 로고
    • Clues about the genetic basis of adaptation emerge from comparing the proteomes of two Ostreococcus ecotypes (Chlorophyta, Prasinophyceae)
    • Jancek, S., S. Gourbiere, H. Moreau and G. Piganeau, 2008 Clues about the genetic basis of adaptation emerge from comparing the proteomes of two Ostreococcus ecotypes (Chlorophyta, Prasinophyceae). Mol. Biol. Evol. 25: 2293-2300.
    • (2008) Mol. Biol. Evol. , vol.25 , pp. 2293-2300
    • Jancek, S.1    Gourbiere, S.2    Moreau, H.3    Piganeau, G.4
  • 42
    • 0034644576 scopus 로고    scopus 로고
    • Deleterious mutations and the evolution of sex
    • Keightley, P., and A. Eyre-Walker, 2000 Deleterious mutations and the evolution of sex. Science 290: 331-333.
    • (2000) Science , vol.290 , pp. 331-333
    • Keightley, P.1    Eyre-Walker, A.2
  • 43
    • 15744388330 scopus 로고    scopus 로고
    • Evidence for widespread degradation of gene control regions in hominid genomes
    • Keightley, P. D., M. J. Lercher and A. Eyre-Walker, 2005 Evidence for widespread degradation of gene control regions in hominid genomes. PLoS Biol. 3: e42.
    • (2005) PLoS Biol. , vol.3
    • Keightley, P.D.1    Lercher, M.J.2    Eyre-Walker, A.3
  • 44
    • 33645765326 scopus 로고    scopus 로고
    • Understanding the degradation of hominid gene control
    • (author reply: e26)
    • Keightley, P. D., M. J. Lercher and A. Eyre-Walker, 2006 Understanding the degradation of hominid gene control. PLoS Comput. Biol. 2: e19 (author reply: e26).
    • (2006) PLoS Comput. Biol. , vol.2
    • Keightley, P.D.1    Lercher, M.J.2    Eyre-Walker, A.3
  • 45
    • 0000800333 scopus 로고
    • On the probability of fixation of mutant genes in a population
    • Kimura, M., 1962 On the probability of fixation of mutant genes in a population. Genetics 47: 713-719.
    • (1962) Genetics , vol.47 , pp. 713-719
    • Kimura, M.1
  • 47
    • 0015862142 scopus 로고
    • The age of a neutral mutant persisting in a finite population
    • Kimura, M., and T. Ohta, 1973 The age of a neutral mutant persisting in a finite population. Genetics 75: 199-212.
    • (1973) Genetics , vol.75 , pp. 199-212
    • Kimura, M.1    Ohta, T.2
  • 48
    • 33644956987 scopus 로고
    • The mutation load in small populations
    • Kimura, M., T. Maruyama and J. F. Crow, 1963 The mutation load in small populations. Genetics 48: 1303-1312.
    • (1963) Genetics , vol.48 , pp. 1303-1312
    • Kimura, M.1    Maruyama, T.2    Crow, J.F.3
  • 49
    • 33644942703 scopus 로고    scopus 로고
    • cDNA-based gene mapping and GC3 profiling in the soft-shelled turtle suggest a chromosomal size-dependent GC bias shared by sauropsids
    • Kuraku, S., J. Ishijima, C. Nishida-Umehara, K. Agata, S. Kuratani et al., 2006 cDNA-based gene mapping and GC3 profiling in the soft-shelled turtle suggest a chromosomal size-dependent GC bias shared by sauropsids. Chromosome Res. 14: 187-202.
    • (2006) Chromosome Res. , vol.14 , pp. 187-202
    • Kuraku, S.1    Ishijima, J.2    Nishida-Umehara, C.3    Agata, K.4    Kuratani, S.5
  • 50
    • 0019953733 scopus 로고
    • The extent to which gene conversion can change allele frequencies in populations
    • Lamb, B. C., and S. Helmi, 1982 The extent to which gene conversion can change allele frequencies in populations. Genet. Res. 39: 199-217.
    • (1982) Genet. Res. , vol.39 , pp. 199-217
    • Lamb, B.C.1    Helmi, S.2
  • 51
    • 0028162824 scopus 로고
    • Risk of population extinction from fixation of new deleterious mutations
    • Lande, R., 1994 Risk of population extinction from fixation of new deleterious mutations. Evolution 48: 1460-1469.
    • (1994) Evolution , vol.48 , pp. 1460-1469
    • Lande, R.1
  • 52
    • 7344220961 scopus 로고    scopus 로고
    • Risk of population extinction from fixation of deleterious and reverse mutations
    • Lande, R., 1998 Risk of population extinction from fixation of deleterious and reverse mutations. Genetica 102/103: 21-27.
    • (1998) Genetica , vol.102-103 , pp. 21-27
    • Lande, R.1
  • 53
    • 0022236684 scopus 로고
    • The evolution of self-fertilization and inbreeding depression in plants. I. Genetic models
    • Lande, R., and D. W. Schemske, 1985 The evolution of self-fertilization and inbreeding depression in plants. I. Genetic models. Evolution 39: 24-40.
    • (1985) Evolution , vol.39 , pp. 24-40
    • Lande, R.1    Schemske, D.W.2
  • 55
    • 0028983653 scopus 로고
    • Mutation accumulation and the extinction of small populations
    • Lynch, M., J. Conery and R. Burger, 1995 Mutation accumulation and the extinction of small populations. Am. Nat. 146: 489-518.
    • (1995) Am. Nat. , vol.146 , pp. 489-518
    • Lynch, M.1    Conery, J.2    Burger, R.3
  • 56
    • 47949108144 scopus 로고    scopus 로고
    • High-resolution mapping of meiotic crossovers and non-crossovers in yeast
    • Mancera, E., R. Bourgon, A. Brozzi, W. Huber and L. M. Steinmetz, 2008 High-resolution mapping of meiotic crossovers and non-crossovers in yeast. Nature 454: 479-485.
    • (2008) Nature , vol.454 , pp. 479-485
    • Mancera, E.1    Bourgon, R.2    Brozzi, A.3    Huber, W.4    Steinmetz, L.M.5
  • 57
    • 0038543069 scopus 로고    scopus 로고
    • Biased gene conversion: Implications for genome and sex evolution
    • Marais, G., 2003 Biased gene conversion: implications for genome and sex evolution. Trends Genet. 19: 330-338.
    • (2003) Trends Genet. , vol.19 , pp. 330-338
    • Marais, G.1
  • 58
    • 0035826858 scopus 로고    scopus 로고
    • Does recombination improve selection on codon usage? Lessons from nematode and fly complete genomes
    • Marais, G., D. Mouchiroud and L. Duret, 2001 Does recombination improve selection on codon usage? Lessons from nematode and fly complete genomes. Proc. Natl. Acad. Sci. USA 98: 5688-5692.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5688-5692
    • Marais, G.1    Mouchiroud, D.2    Duret, L.3
  • 59
    • 0037648944 scopus 로고    scopus 로고
    • Neutral effect of recombination on base compositionin Drosophila
    • Marais, G., D. Mouchiroud and L. Duret, 2003 Neutral effect of recombination on base compositionin Drosophila. Genet. Res. 81: 79-87.
    • (2003) Genet. Res. , vol.81 , pp. 79-87
    • Marais, G.1    Mouchiroud, D.2    Duret, L.3
  • 60
    • 4143105022 scopus 로고    scopus 로고
    • Recombination and base composition: The case of the highly self-fertilizing plant Arabidopsis thaliana
    • Marais, G., B. Charlesworth and S. I. Wright, 2004 Recombination and base composition: the case of the highly self-fertilizing plant Arabidopsis thaliana. Genome Biol. 5: R45.
    • (2004) Genome Biol. , vol.5
    • Marais, G.1    Charlesworth, B.2    Wright, S.I.3
  • 61
    • 70350142948 scopus 로고    scopus 로고
    • GC content and recombination: Reassessing the causal effects for the Saccharomyces cerevisiae genome
    • Marsolier-Kergoat, M. C., and E. Yeramian, 2009 GC content and recombination: reassessing the causal effects for the Saccharomyces cerevisiae genome. Genetics 183: 31-38.
    • (2009) Genetics , vol.183 , pp. 31-38
    • Marsolier-Kergoat, M.C.1    Yeramian, E.2
  • 62
    • 2142773942 scopus 로고    scopus 로고
    • The fine-scale structure of recombination rate variation in the human genome
    • McVean, G. A., S. R. Myers, S. Hunt, P. Deloukas, D. R. Bentley et al., 2004 The fine-scale structure of recombination rate variation in the human genome. Science 304: 581-584.
    • (2004) Science , vol.304 , pp. 581-584
    • McVean, G.A.1    Myers, S.R.2    Hunt, S.3    Deloukas, P.4    Bentley, D.R.5
  • 63
    • 2442651458 scopus 로고    scopus 로고
    • Recombination drives the evolution of GC-content in the human genome
    • Meunier, J., and L. Duret, 2004 Recombination drives the evolution of GC-content in the human genome. Mol. Biol. Evol. 21: 984-990.
    • (2004) Mol. Biol. Evol. , vol.21 , pp. 984-990
    • Meunier, J.1    Duret, L.2
  • 64
    • 26844482093 scopus 로고    scopus 로고
    • A fine-scale map of recombination rates and hotspots across the human genome
    • Myers, S., L. Bottolo, C. Freeman, G. McVean and P. Donnelly, 2005 A fine-scale map of recombination rates and hotspots across the human genome. Science 310: 321-324.
    • (2005) Science , vol.310 , pp. 321-324
    • Myers, S.1    Bottolo, L.2    Freeman, C.3    McVean, G.4    Donnelly, P.5
  • 65
    • 0021077332 scopus 로고
    • Evolution of a finite population under gene conversion
    • Nagylaki, T., 1983a Evolution of a finite population under gene conversion. Proc. Natl. Acad. Sci. USA 80: 6278-6281.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 6278-6281
    • Nagylaki, T.1
  • 66
    • 0021022685 scopus 로고
    • Evolution of a large population under gene conversion
    • Nagylaki, T., 1983b Evolution of a large population under gene conversion. Proc. Natl. Acad. Sci. USA 80: 5941-5945.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 5941-5945
    • Nagylaki, T.1
  • 67
    • 29444452921 scopus 로고    scopus 로고
    • Molecular signatures of natural selection
    • Nielsen, R., 2005 Molecular signatures of natural selection. Annu. Rev. Genet. 39: 197-218.
    • (2005) Annu. Rev. Genet. , vol.39 , pp. 197-218
    • Nielsen, R.1
  • 68
    • 33645217623 scopus 로고    scopus 로고
    • Molecular features of meiotic recombination hotspots
    • Nishant, K. T., and M. R. S. Rao, 2005 Molecular features of meiotic recombination hotspots. BioEssays 28: 45-56.
    • (2005) BioEssays , vol.28 , pp. 45-56
    • Nishant, K.T.1    Rao, M.R.S.2
  • 69
    • 0030822809 scopus 로고    scopus 로고
    • The coalescent process with selfing
    • Nordborg, M., and P. Donnelly, 1997 The coalescent process with selfing. Genetics 146: 1185-1195.
    • (1997) Genetics , vol.146 , pp. 1185-1195
    • Nordborg, M.1    Donnelly, P.2
  • 70
    • 0029962309 scopus 로고    scopus 로고
    • The effect of recombination on background selection
    • Nordborg, M., B. Charlesworth and D. Charlesworth, 1996 The effect of recombination on background selection. Genet. Res. 67: 159-174.
    • (1996) Genet. Res. , vol.67 , pp. 159-174
    • Nordborg, M.1    Charlesworth, B.2    Charlesworth, D.3
  • 71
    • 0016148740 scopus 로고
    • Detrimental genes with partial selfing and effects on a neutral locus
    • Ohta, T., and C. C. Cockerham, 1974 Detrimental genes with partial selfing and effects on a neutral locus. Genet. Res. 23: 191-200.
    • (1974) Genet. Res. , vol.23 , pp. 191-200
    • Ohta, T.1    Cockerham, C.C.2
  • 72
    • 0023427397 scopus 로고
    • On the theory of partially inbreeding finite populations. I. Partial selfing
    • Pollak, E., 1987 On the theory of partially inbreeding finite populations. I. Partial selfing. Genetics 117: 353-360.
    • (1987) Genetics , vol.117 , pp. 353-360
    • Pollak, E.1
  • 74
    • 33748675254 scopus 로고    scopus 로고
    • An RNA gene expressed during cortical development evolved rapidly in humans
    • Pollard, K. S., S. R. Salama, N. Lambert, M. A. Lambot, S. Coppens et al., 2006b An RNA gene expressed during cortical development evolved rapidly in humans. Nature 443: 167-172.
    • (2006) Nature , vol.443 , pp. 167-172
    • Pollard, K.S.1    Salama, S.R.2    Lambert, N.3    Lambot, M.A.4    Coppens, S.5
  • 75
    • 33750737061 scopus 로고    scopus 로고
    • Accelerated evolution of conserved noncoding sequences in humans
    • Prabhakar, S., J. P. Noonan, S. Paabo and E. M. Rubin, 2006 Accelerated evolution of conserved noncoding sequences in humans. Science 314: 786.
    • (2006) Science , vol.314 , pp. 786
    • Prabhakar, S.1    Noonan, J.P.2    Paabo, S.3    Rubin, E.M.4
  • 76
    • 51149097366 scopus 로고    scopus 로고
    • Human-specific gain of function in a developmental enhancer
    • Prabhakar, S., A. Visel, J. A. Akiyama, M. Shoukry, K. D. Lewis et al., 2008 Human-specific gain of function in a developmental enhancer. Science 321: 1346-1350.
    • (2008) Science , vol.321 , pp. 1346-1350
    • Prabhakar, S.1    Visel, A.2    Akiyama, J.A.3    Shoukry, M.4    Lewis, K.D.5
  • 77
    • 61849143272 scopus 로고    scopus 로고
    • Recombinational landscape and population genomics of Caenorhabditis elegans
    • Rockman, M. V., and L. Kruglyak, 2009 Recombinational landscape and population genomics of Caenorhabditis elegans. PLoS Genet. 5: e1000419.
    • (2009) PLoS Genet. , vol.5
    • Rockman, M.V.1    Kruglyak, L.2
  • 79
    • 0025366147 scopus 로고
    • A simple genealogical structure of strongly balanced allelic lines and trans-species evolution of polymorphism
    • Takahata, N., 1990 A simple genealogical structure of strongly balanced allelic lines and trans-species evolution of polymorphism. Proc. Natl. Acad. Sci. USA 87: 2419-2423.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 2419-2423
    • Takahata, N.1
  • 80
    • 0000951644 scopus 로고    scopus 로고
    • Is self-fertilization an evolutionary dead end? Revisiting an old hypothesis with genetic theories and a macroevolutionary approach
    • Takebayashi, N., and P. L. Morrell, 2001 Is self-fertilization an evolutionary dead end? Revisiting an old hypothesis with genetic theories and a macroevolutionary approach. Am. J. Bot. 88: 1143-1150.
    • (2001) Am. J. Bot. , vol.88 , pp. 1143-1150
    • Takebayashi, N.1    Morrell, P.L.2
  • 81
    • 0026360286 scopus 로고
    • Coevolution of self-fertilization and inbreeding depression. II. Symmetric overdominance in viability
    • Uyenoyama, M. K., and D. M. Waller, 1991 Coevolution of self-fertilization and inbreeding depression. II. Symmetric overdominance in viability. Theor. Popul. Biol. 40: 47-77.
    • (1991) Theor. Popul. Biol. , vol.40 , pp. 47-77
    • Uyenoyama, M.K.1    Waller, D.M.2
  • 82
    • 33746685034 scopus 로고    scopus 로고
    • Comparative analysis of expressed sequences reveals a conserved pattern of optimal codon usage in plants
    • Wang, L. J., and M. J. Roossinck, 2006 Comparative analysis of expressed sequences reveals a conserved pattern of optimal codon usage in plants. Plant Mol. Biol. 61: 699-710.
    • (2006) Plant Mol. Biol. , vol.61 , pp. 699-710
    • Wang, L.J.1    Roossinck, M.J.2
  • 83
    • 33646884615 scopus 로고    scopus 로고
    • Strong regional biases in nucleotide substitution in the chicken genome
    • Webster, M. T., E. Axelsson and H. Ellegren, 2006 Strong regional biases in nucleotide substitution in the chicken genome. Mol. Biol. Evol. 23: 1203-1216.
    • (2006) Mol. Biol. Evol. , vol.23 , pp. 1203-1216
    • Webster, M.T.1    Axelsson, E.2    Ellegren, H.3
  • 84
    • 0034124425 scopus 로고    scopus 로고
    • Local drift load and the heterosis of interconnected populations
    • Whitlock, M. C., P. K. Ingvarsson and T. Hatfield, 2000 Local drift load and the heterosis of interconnected populations. Heredity 84: 452-457.
    • (2000) Heredity , vol.84 , pp. 452-457
    • Whitlock, M.C.1    Ingvarsson, P.K.2    Hatfield, T.3
  • 85
    • 0004149831 scopus 로고    scopus 로고
    • Cambridge University Press, Cambridge, UK
    • Wolfram, S., 1996 The Mathematica Book. Cambridge University Press, Cambridge, UK.
    • (1996) The Mathematica Book
    • Wolfram, S.1
  • 86
    • 0001111820 scopus 로고
    • The distribution of gene frequencies in populations
    • Wright, S., 1937 The distribution of gene frequencies in populations. Proc. Natl. Acad. Sci. USA 23: 307-320.
    • (1937) Proc. Natl. Acad. Sci. USA , vol.23 , pp. 307-320
    • Wright, S.1
  • 87
    • 33845884049 scopus 로고    scopus 로고
    • Neutral evolution of synonymous base composition in the Brassicaceae
    • Wright, S. I., G. Iorgovan, S. Misra and M. Mokhtari, 2007 Neutral evolution of synonymous base composition in the Brassicaceae. J. Mol. Evol. 64: 136-141.
    • (2007) J. Mol. Evol. , vol.64 , pp. 136-141
    • Wright, S.I.1    Iorgovan, G.2    Misra, S.3    Mokhtari, M.4
  • 88
    • 0000983314 scopus 로고
    • Inbreeding depression due to overdominance in partially self-fertilizing plant populations
    • Ziehe, M., and J. H. Roberds, 1989 Inbreeding depression due to overdominance in partially self-fertilizing plant populations. Genetics 121: 861-868.
    • (1989) Genetics , vol.121 , pp. 861-868
    • Ziehe, M.1    Roberds, J.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.