Synthetic pseudopterosin analogues: A novel class of antiinflammatory drug candidates

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 23, 2010, Pages 8324-8333

  Flachsmann, Felix ^a   Schellhaas, Kurt ^a   Moya, Claudia E ^b   Jacobs, Robert S ^b   Fenical, William ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Anti inflammatory; Catechol glycosides; Mouse ear assay; Pseudopterosins

Indexed keywords

1 (3,4 DIMETHOXYPHENYL)OCT 7 EN 4 OL; 1 (BUT 3 ENYL) 6,7 DIMETHOXY 1,2,3,4 TETRAHYDRONAPHTHALENE; 2 [2 (6,7 DIMETHOXY 1,2,3,4 TETRAHYDRONAPHTHALEN 1 YL)ETHYL] 1,3 DIOXOLANE; 3 (6,7 DIMETHOXY 1,2,3,4 TETRAHYDRONAPHTHALEN 1 YL)PROPANAL; 3 (6,7 DIMETHOXY 1,2,3,4 TETRAHYDRONAPHTHALEN 1 YL)PROPANOIC ACID; 4 HYDROXY 2,3,7,8,9,9A HEXAHYDRO 1H PHENALEN 4 YL 6 DEOXY ALPHA LEVO GALACTOPYRANOSIDE; 4 HYDROXY 2,3,7,8,9,9A HEXAHYDRO 1H PHENALEN 5 YL DEXTRO XYLOPYRANOSIDE; 4 HYDROXY 3,3 DIMETHYL 2,3,7,8,9,9A HEXAHYDRO 1H PHENALEN-5 YL 6 DEOXY ALPHA LEVO GALACTOPYRANOSIDE; 5 HYDROXY 2,3,7,8,9,9A HEXAHYDRO 1H PHENALEN 4 YL 6 DEOXY ALPHA LEVO GALACTOPYRANOSIDE; 5 HYDROXY 2,3,7,8,9,9A HEXAHYDRO 1H PHENALEN 4 YL DEXTRO XYLOPYRANOSIDE; 5 HYDROXY 6 METHYL 2,3,7,8,9,9A HEXAHYDRO 1H PHENALEN 4 YL 6 DEOXY ALPHA LEVO GALACTOPYRANOSIDE; 5 HYDROXY 6 TRIFLUOROMETHYL 2,3,7,8,9,9A HEXAHYDRO 1H PHENALEN 4 YL 6 DEOXY ALPHA LEVO GALACTOPYRANOSIDE; 7 BROMO 8,9 DIMETHOXY 2,3,3A,4,5,6 HEXAHYDRO 1H PHENALENE; 7,8 DIMETHOXY 2,3,3A,4,5,6 HEXAHYDRO 1H PHENALENE; 7,8 DIMETHOXY 9 METHYL 2,3,3A,4,5,6 HEXAHYDRO 1H PHENALENE; 7,8 DIMETHOXY 9 TRIFLUOROMETHYL 2,3,3A,4,5,6 HEXAHYDRO 1H PHENALENE; 8,9 DIMETHOXY 1 METHYL 2,3,3A,4,5,6 HEXAHYDRO 1H PHENALENE; 8,9 DIMETHOXY 1 METHYL-2,3,3A,4,5,6 HEXAHYDRO 1H 8,9 DIMETHOXY 1 METHYL 2,3,3A,4,5,6 HEXAHYDRO 1H PHENALENE; 8,9 DIMETHOXY 1,1 DIMETHYL 2,3,3A,4,5,6 HEXAHYDRO 1H PHENALENE; 8,9 DIMETHOXY 2,3,3A,4,5,6 HEXAHYDRO 1H PHENALEN 1 ONE; 9 HYDROXY 2,3,3A,4,5,6 HEXAHYDRO 1H PHENALEN 1 ON 8 YL 6 DEOXY ALPHA LEVO GALACTOPYRANOSIDE; ANTIINFLAMMATORY AGENT; CATECHOL DERIVATIVE; PHORBOL 13 ACETATE 12 MYRISTATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG STRUCTURE; MOUSE; NONHUMAN;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CATECHOLS; DITERPENES; GALACTOSIDES; GLYCOSIDES; INFLAMMATION; MICE; PHENALENES; STRUCTURE-ACTIVITY RELATIONSHIP; TETRADECANOYLPHORBOL ACETATE;

EID: 78249245719     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.09.067     Document Type: Article

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