Leupeptin-based inhibitors do not improve the mdx phenotype

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 299, Issue 5, 2010, Pages

  Selsby, Joshua ^a   Pendrak, Klara ^a   Zadel, Monica ^a   Tian, Zuozhen ^a   Pham, Jennifer ^a   Carver, Ted ^b   Acosta, Pedro ^a   Barton, Elisabeth ^a   Sweeney, H Lee ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CepTor Corporation   (United States)

Author keywords

Calpain; Muscular dystrophy; Protease; Skeletal muscle

Indexed keywords

C101; CALPAIN; CALPASTATIN; CREATINE KINASE; CYSTEINE PROTEINASE INHIBITOR; LEUPEPTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOLYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FIBROSIS; IMMUNOHISTOCHEMISTRY; MOUSE; MUSCLE FUNCTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

ANIMALS; BIOLOGICAL MARKERS; CALCIUM-BINDING PROTEINS; CALPAIN; CREATINE KINASE; CYSTEINE PROTEINASE INHIBITORS; DIAPHRAGM; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GENOTYPE; LEUPEPTINS; MICE; MICE, INBRED MDX; MUSCLE CONTRACTION; MUSCLE STRENGTH; MUSCULAR DYSTROPHY, DUCHENNE; NECROSIS; PHENOTYPE; PROTEASOME ENDOPEPTIDASE COMPLEX; TIME FACTORS;

EID: 78149487689     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00586.2009     Document Type: Article

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