Effect of calpain and proteasome inhibition on Ca2+-dependent proteolysis and muscle histopathology in the mdx mouse

FASEB Journal

Volumn 22, Issue 12, 2008, Pages 4190-4200

  Briguet, Alexandre ^a   Erb, Michael ^a   Courdier Fruh, Isabelle ^a   Barzaghi, Patrizia ^a   Santos, Gesa ^a   Herzner, Holger ^a   Lescop, Cyrille ^a   Siendt, Hervé ^a   Henneboehle, Marco ^a   Weyermann, Philipp ^a   Magyar, Josef P ^a   Dubach Powell, Judith ^a   Metz, Günther ^a,b   Meier, Thomas ^a  

^a Santhera Pharmaceuticals   (Switzerland)

^b Santhera Pharmaceuticals   (Switzerland)

Author keywords

Calpastatin; Duchenne muscular dystrophy; Dystrophin deficiency; In vivo efficacy; Small molecule inhibitors

Indexed keywords

CALPAIN; DYSTROPHIN; PROTEINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CONTROLLED STUDY; DUCHENNE MUSCULAR DYSTROPHY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; HISTOPATHOLOGY; MALE; MOUSE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

ANIMALS; CALCIUM; CALCIUM-BINDING PROTEINS; CALPAIN; CELLS, CULTURED; HUMANS; MICE; MICE, INBRED MDX; MICE, TRANSGENIC; MUSCLES; MUSCULAR DYSTROPHY, DUCHENNE; MYOBLASTS; OLIGOPEPTIDES; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX;

MUS; MUS MUSCULUS;

EID: 57349151705     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-099036     Document Type: Article

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