Novel cell-penetrating α-keto-amide calpain inhibitors as potential treatment for muscular dystrophy

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 23, 2005, Pages 5176-5181

  Lescop, Cyrille ^a   Herzner, Holger ^a   Siendt, Hervé ^a   Bolliger, Reto ^a   Henneböhle, Marco ^a   Weyermann, Philipp ^a   Briguet, Alexandre ^a   Courdier Fruh, Isabelle ^a   Erb, Michael ^a   Foster, Mark ^a   Meier, Thomas ^a   Magyar, Josef P ^a   Von Sprecher, Andreas ^a  

^a Santhera Pharmaceuticals   (Switzerland)

Author keywords

Calpain inhibitor; Duchenne muscular dystrophy; Keto amide

Indexed keywords

[1 [(1 FORMYL 2 PHENYLETHYL)CARBAMOYL] 2 METHYLPROPYL]CARBAMIC ACID BENZYL ESTER; CALPASTATIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MEMBRANE PERMEABILITY; COVALENT BOND; DEPROTECTION REACTION; DUCHENNE MUSCULAR DYSTROPHY; HISTOLOGY; IC 50; MOUSE; MUSCLE CELL; NONHUMAN;

AMIDES; ANIMALS; CALPAIN; CYSTEINE PROTEINASE INHIBITORS; DIAPHRAGM; DIPEPTIDES; MICE; MICE, INBRED MDX; MOLECULAR STRUCTURE; MUSCULAR DYSTROPHY, ANIMAL;

ANIMALIA;

EID: 26844503135     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.08.064     Document Type: Article

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