메뉴 건너뛰기




Volumn 104, Issue 5, 2010, Pages 1044-1048

Oral thrombostatin FM19 inhibits prostate cancer

Author keywords

Anticoagulation; Cancer treatment; Oral direct thrombin inhibitor; Prostate cancer

Indexed keywords

FM 19; HIRULOG; PROTEINASE ACTIVATED RECEPTOR 1; THROMBIN; THROMBIN INHIBITOR; UNCLASSIFIED DRUG;

EID: 78149481975     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH09-08-0570     Document Type: Article
Times cited : (18)

References (25)
  • 1
    • 0031842760 scopus 로고    scopus 로고
    • The role of integrins in tumorigenesis and metastasis
    • Sanders RJ, Mainiero F, Giancotti FG. The role of integrins in tumorigenesis and metastasis. Cancer Invest 1998; 16: 329-344.
    • (1998) Cancer Invest , vol.16 , pp. 329-344
    • Sanders, R.J.1    Mainiero, F.2    Giancotti, F.G.3
  • 2
    • 0032514402 scopus 로고    scopus 로고
    • Vascular targeting as a strategy for cancer therapy
    • Schnitzer JE. Vascular targeting as a strategy for cancer therapy. N Engl J Med 1998; 339: 472-474.
    • (1998) N Engl J Med , vol.339 , pp. 472-474
    • Schnitzer, J.E.1
  • 3
    • 65949104849 scopus 로고    scopus 로고
    • Thrombin induces tumor cell cycle activation and spontaneous growth by down-regulation of p27Kip1, in association with the up-regulation of Skp2 and MiR-222
    • Hu L, Ibrahim S, Liu C, et al. Thrombin induces tumor cell cycle activation and spontaneous growth by down-regulation of p27Kip1, in association with the up-regulation of Skp2 and MiR-222. Cancer Res 2009; 69: 3374-3381.
    • (2009) Cancer Res , vol.69 , pp. 3374-3381
    • Hu, L.1    Ibrahim, S.2    Liu, C.3
  • 4
    • 7244231210 scopus 로고    scopus 로고
    • Role of endogenous thrombin in tumor implantation, seeding, and spontaneous metastasis
    • Hu L, Lee M, Campbell W, et al. Role of endogenous thrombin in tumor implantation, seeding, and spontaneous metastasis. Blood 2004; 104: 2746-2751.
    • (2004) Blood , vol.104 , pp. 2746-2751
    • Hu, L.1    Lee, M.2    Campbell, W.3
  • 5
    • 0036845746 scopus 로고    scopus 로고
    • A functional thrombin receptor (PAR1) is expressed on bone-derived prostate cancer cell lines
    • Chay CH, Cooper CR, Gendernalik JD, et al. A functional thrombin receptor (PAR1) is expressed on bone-derived prostate cancer cell lines. Urology 2002; 60: 760-765.
    • (2002) Urology , vol.60 , pp. 760-765
    • Chay, C.H.1    Cooper, C.R.2    Gendernalik, J.D.3
  • 6
    • 27144507922 scopus 로고    scopus 로고
    • PAR1-mediated NFkappaB activation promotes survival of prostate cancer cells through a Bcl-xL-dependent mechanism
    • Tantivejkul K, Loberg RD, Mawocha SC, et al. PAR1-mediated NFkappaB activation promotes survival of prostate cancer cells through a Bcl-xL-dependent mechanism. J Cell Biochem 2005; 96: 641-652.
    • (2005) J Cell Biochem , vol.96 , pp. 641-652
    • Tantivejkul, K.1    Loberg, R.D.2    Mawocha, S.C.3
  • 7
    • 0043065369 scopus 로고    scopus 로고
    • Expression of functional protease-activated receptor 1 in human prostate cancer cell lines
    • Liu J, Bastian M, Kohlschein P, et al. Expression of functional protease-activated receptor 1 in human prostate cancer cell lines. Urol Res 2003; 31: 163-168.
    • (2003) Urol Res , vol.31 , pp. 163-168
    • Liu, J.1    Bastian, M.2    Kohlschein, P.3
  • 8
    • 11144231266 scopus 로고    scopus 로고
    • Protease-activated receptor 1: A role in prostate cancer metastasis
    • Yuan TC, Lin MF. Protease-activated receptor 1: a role in prostate cancer metastasis. Clin Prostate Cancer 2004; 3: 189-191.
    • (2004) Clin Prostate Cancer , vol.3 , pp. 189-191
    • Yuan, T.C.1    Lin, M.F.2
  • 9
    • 31944448553 scopus 로고    scopus 로고
    • Thrombin receptor expression is upregulated in prostate cancer
    • Kaushal V, Kohli M, Dennis RA, et al. Thrombin receptor expression is upregulated in prostate cancer. Prostate 2006; 66: 273-282.
    • (2006) Prostate , vol.66 , pp. 273-282
    • Kaushal, V.1    Kohli, M.2    Dennis, R.A.3
  • 10
    • 0037308089 scopus 로고    scopus 로고
    • Oncogenic transformation induces tumor angiogenesis: A role for PAR1 activation
    • Yin YJ, Salah Z, Maoz M, et al. Oncogenic transformation induces tumor angiogenesis: a role for PAR1 activation. FASEB J 2003; 17: 163-174.
    • (2003) FASEB J , vol.17 , pp. 163-174
    • Yin, Y.J.1    Salah, Z.2    Maoz, M.3
  • 11
    • 0037783286 scopus 로고    scopus 로고
    • Human protease-activated receptor 1 expression in malignant epithelia: A role in invasiveness
    • Yin YJ, Salah Z, Grisaru-Granovsky S, et al. Human protease-activated receptor 1 expression in malignant epithelia: a role in invasiveness. Arterioscler Thromb Vasc Biol 2003; 23: 940-944.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 940-944
    • Yin, Y.J.1    Salah, Z.2    Grisaru-Granovsky, S.3
  • 12
    • 0027201786 scopus 로고
    • Thrombin increases the metastatic potential of tumor cells
    • Wojtukiewicz MZ, Tang DG, Ciarelli JJ, et al. Thrombin increases the metastatic potential of tumor cells. Int J Cancer 1993; 54: 793-806.
    • (1993) Int J Cancer , vol.54 , pp. 793-806
    • Wojtukiewicz, M.Z.1    Tang, D.G.2    Ciarelli, J.J.3
  • 13
    • 0032533268 scopus 로고    scopus 로고
    • Protease-activated receptor 1 (PAR-1) is required and rate-limiting for thrombin-enhanced experimental pulmonary metastasis
    • Nierodzik ML, Chen K, Takeshita K, et al. Protease-activated receptor 1 (PAR-1) is required and rate-limiting for thrombin-enhanced experimental pulmonary metastasis. Blood 1998; 92: 3694-3700.
    • (1998) Blood , vol.92 , pp. 3694-3700
    • Nierodzik, M.L.1    Chen, K.2    Takeshita, K.3
  • 14
    • 0035421226 scopus 로고    scopus 로고
    • Signaling from protease-activated receptor-1 inhibits migration and invasion of breast cancer cells
    • Kamath L, Meydani A, Foss F, et al. Signaling from protease-activated receptor-1 inhibits migration and invasion of breast cancer cells. Cancer Res 2001; 61: 5933-5940.
    • (2001) Cancer Res , vol.61 , pp. 5933-5940
    • Kamath, L.1    Meydani, A.2    Foss, F.3
  • 15
    • 3543121913 scopus 로고    scopus 로고
    • Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis
    • Shi X, Gangadharan B, Brass LF, et al. Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis. Mol Cancer Res 2004; 2: 395-402.
    • (2004) Mol Cancer Res , vol.2 , pp. 395-402
    • Shi, X.1    Gangadharan, B.2    Brass, L.F.3
  • 16
    • 11244255408 scopus 로고    scopus 로고
    • Identification of a novel functional androgen response element within hPar1 promoter: Implications to prostate cancer progression
    • Salah Z, Maoz M, Cohen I, et al. Identification of a novel functional androgen response element within hPar1 promoter: implications to prostate cancer progression. FASEB J 2005; 19: 62-72.
    • (2005) FASEB J , vol.19 , pp. 62-72
    • Salah, Z.1    Maoz, M.2    Cohen, I.3
  • 17
    • 35448985707 scopus 로고    scopus 로고
    • Transcriptional regulation of human protease-activated receptor 1: A role for the early growth response-1 protein in prostate cancer
    • Salah Z, Maoz M, Pizov G, et al. Transcriptional regulation of human protease-activated receptor 1: a role for the early growth response-1 protein in prostate cancer. Cancer Res 2007; 67: 9835-9843.
    • (2007) Cancer Res , vol.67 , pp. 9835-9843
    • Salah, Z.1    Maoz, M.2    Pizov, G.3
  • 19
    • 6344247582 scopus 로고    scopus 로고
    • The preparation and characterization of novel peptide antagonists to thrombin and factor VIIa and activation of protease- activated receptor 1
    • Nieman MT, Warnock M, Hasan AA, et al. The preparation and characterization of novel peptide antagonists to thrombin and factor VIIa and activation of protease- activated receptor 1. J Pharmacol Exp Ther 2004; 311: 492-501.
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 492-501
    • Nieman, M.T.1    Warnock, M.2    Hasan, A.A.3
  • 20
    • 33845535102 scopus 로고    scopus 로고
    • Synthesis of novel peptide inhibitors of thrombin-induced platelet activation
    • Burke FM, Warnock M, Schmaier AH, et al. Synthesis of novel peptide inhibitors of thrombin-induced platelet activation. Chem Biol Drug Des 2006; 68: 235-238.
    • (2006) Chem Biol Drug des , vol.68 , pp. 235-238
    • Burke, F.M.1    Warnock, M.2    Schmaier, A.H.3
  • 21
    • 42149143441 scopus 로고    scopus 로고
    • Thrombostatin FM compounds: Direct thrombin inhibitors - Mechanism of action in vitro and in vivo
    • Nieman MT, Burke F, Warnock M, et al. Thrombostatin FM compounds: direct thrombin inhibitors - mechanism of action in vitro and in vivo. J Thromb Haemost 2008; 6: 837-845.
    • (2008) J Thromb Haemost , vol.6 , pp. 837-845
    • Nieman, M.T.1    Burke, F.2    Warnock, M.3
  • 22
    • 15444365985 scopus 로고    scopus 로고
    • Bone turnover mediates preferential localization of prostate cancer in the skeleton
    • Schneider A, Kalikin LM, Mattos AC, et al. Bone turnover mediates preferential localization of prostate cancer in the skeleton. Endocrinology 2005; 146: 1727-1736.
    • (2005) Endocrinology , vol.146 , pp. 1727-1736
    • Schneider, A.1    Kalikin, L.M.2    Mattos, A.C.3
  • 23
    • 0026718393 scopus 로고
    • Parameter estimation by least-squares methods
    • Johnson ML, Faunt LM. Parameter estimation by least-squares methods. Methods Enzymol 1992; 210: 1-37.
    • (1992) Methods Enzymol , vol.210 , pp. 1-37
    • Johnson, M.L.1    Faunt, L.M.2
  • 24
    • 0026719686 scopus 로고
    • Global analysis of biochemical and biophysical data
    • Beechem JM. Global analysis of biochemical and biophysical data. Methods Enzymol 1992; 210: 37-54.
    • (1992) Methods Enzymol , vol.210 , pp. 37-54
    • Beechem, J.M.1
  • 25
    • 0027412203 scopus 로고
    • Peptide carrier-mediate transport in interstinal brush border membrane vesicles of rats and rabbits: Cephradine uptake and inhibition
    • Yuasa H, Amidon GL, Fleisher D. peptide carrier-mediate transport in interstinal brush border membrane vesicles of rats and rabbits: cephradine uptake and inhibition. Pharm Res. 1993; 10: 400-404.
    • (1993) Pharm Res , vol.10 , pp. 400-404
    • Yuasa, H.1    Amidon, G.L.2    Fleisher, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.