Synthesis of novel peptide inhibitors of thrombin-induced platelet activation

Chemical Biology and Drug Design

Volumn 68, Issue 5, 2006, Pages 235-238

  Burke, Fernanda M ^a   Warnock, Mark ^b   Schmaier, Alvin H ^c   Mosberg, Henry I ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bradykinin; Platelet aggregation; Protease activated receptor; Thrombin; Thrombin receptor

Indexed keywords

BRADYKININ; BRADYKININ[1-5]; FM 19; GAMMA THROMBIN; PEPTIDE; PEPTIDE DERIVATIVE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 4; SERINE PROTEINASE; TH 146; THROMBIN; THROMBIN RECEPTOR;

ACUTE CORONARY SYNDROME; AMINO TERMINAL SEQUENCE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; DRUG SYNTHESIS; ENZYME BINDING; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION INHIBITION;

AMINO ACID SEQUENCE; BRADYKININ; HUMANS; LIGANDS; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PLATELET ACTIVATION; PLATELET AGGREGATION INHIBITORS; RECEPTOR, PAR-1; RECEPTORS, THROMBIN; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN;

EID: 33845535102     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2006.00442.x     Document Type: Article

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