Activation of the CMV-IE promoter by hyperthermia in vitro and in vivo: Biphasic heat induction of cytosine deaminase suicide gene expression

Molecular Biotechnology

Volumn 46, Issue 2, 2010, Pages 197-205

  Kobelt, Dennis ^a   Aumann, Jutta ^a   Fichtner, Iduna ^a   Stein, Ulrike ^a   Schlag, Peter M ^a,b   Walther, Wolfgang ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Cancer; CMV promoter; Cytosine deaminase; Gene therapy; Heat induction; Hyperthermia; Transcription factor

Indexed keywords

CANCER; CMV-PROMOTER; CYTOSINE DEAMINASE; HEAT INDUCTION; HYPERTHERMIA;

ANIMALS; BEARINGS (STRUCTURAL); BINDING ENERGY; BINDING SITES; BIOCHEMISTRY; GENETIC ENGINEERING; HYPERTHERMIA THERAPY; TRANSCRIPTION; TRANSCRIPTION FACTORS; TUMORS;

GENE THERAPY;

CCAAT ENHANCER BINDING PROTEIN BETA; CYTOSINE DEAMINASE; HEAT SHOCK PROTEIN 70; IMMEDIATE EARLY PROTEIN; TRANSCRIPTION FACTOR; Y BOX BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CARCINOMA CELL; COLON CARCINOMA; CONTROLLED STUDY; CYTOMEGALOVIRUS; GENE EXPRESSION; HEAT TREATMENT; HUMAN; HUMAN CELL; HYPERTHERMIA; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PROMOTER REGION; SEQUENCE ANALYSIS; STRESS; SUICIDE GENE; VIRAL GENE DELIVERY SYSTEM; VIRUS ACTIVATION;

ANIMALS; CELL LINE, TUMOR; COLONIC NEOPLASMS; CYTOSINE DEAMINASE; DISEASE MODELS, ANIMAL; ENZYME INDUCTION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE THERAPY; HUMANS; HYPERTHERMIA, INDUCED; MALE; MICE; MICE, INBRED NOD; PROMOTER REGIONS, GENETIC; TRANSCRIPTION FACTORS;

ANIMALIA; BACTERIA (MICROORGANISMS); CYTOMEGALOVIRUS;

EID: 78149470251     PISSN: 10736085     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12033-010-9292-3     Document Type: Article

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