The human host defense peptide LL-37 interacts with Neisseria meningitidis capsular polysaccharides and inhibits inflammatory mediators release

PLoS ONE

Volumn 5, Issue 10, 2010, Pages

  Zughaier, Susu M ^a   Svoboda, Pavel ^a,c   Pohl, Jan ^a,c   Stephens, David S ^a,b   Shafer, William M ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMICROBIAL CATIONIC PEPTIDE; BACTERIAL POLYSACCHARIDE; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUCAN; INTERLEUKIN 6; INTERLEUKIN 8; LIGAND; MENINGOCOCCUS VACCINE; NITRIC OXIDE; PROTEIN MD 2; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; VIRULENCE FACTOR; CAP18 LIPOPOLYSACCHARIDE BINDING PROTEIN; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN; CYTOKINE;

ANIMAL CELL; ANTIGEN BINDING; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG RESPONSE; EPITHELIUM CELL; HOST PATHOGEN INTERACTION; HOST RESISTANCE; HUMAN; HUMAN CELL; INFLAMMATION; MACROPHAGE; MACROPHAGE ACTIVATION; MEDIATOR RELEASE; MOLECULAR INTERACTION; MOUSE; NEISSERIA MENINGITIDIS; NONHUMAN; PHAGOCYTE; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY;

MURINAE; NEISSERIA MENINGITIDIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL LINE; CYTOKINES; HUMANS; MACROPHAGES; MICE; MOLECULAR SEQUENCE DATA; NEISSERIA MENINGITIDIS; POLYSACCHARIDES, BACTERIAL;

EID: 78149423945     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013627     Document Type: Article

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