Inhibition of cathelicidin activity by bacterial exopolysaccharides

Molecular Microbiology

Volumn 72, Issue 5, 2009, Pages 1137-1146

  Foschiatti, Michela ^a   Cescutti, Paola ^a   Tossi, Alessandro ^a   Rizzo, Roberto ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CATHELICIDIN; EXOPOLYSACCHARIDE; POLYPEPTIDE ANTIBIOTIC AGENT;

ANTIMICROBIAL ACTIVITY; ARTICLE; ATOMIC FORCE MICROSCOPY; BACTERIUM; BURKHOLDERIA CEPACIA COMPLEX; CIRCULAR DICHROISM; COMPLEX FORMATION; ESCHERICHIA COLI; FLUORESCENCE SPECTROSCOPY; INQUILINUS LIMOSUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PSEUDOMONAS AERUGINOSA;

ANIMALS; BURKHOLDERIA CEPACIA COMPLEX; CATHELICIDINS; CIRCULAR DICHROISM; CYSTIC FIBROSIS; ESCHERICHIA COLI; HAPLORHINI; HUMANS; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, ATOMIC FORCE; MOLECULAR CONFORMATION; POLYSACCHARIDES, BACTERIAL; PONGO PYGMAEUS; PSEUDOMONAS AERUGINOSA; RHODOSPIRILLACEAE; SPECTROMETRY, FLUORESCENCE;

BACTERIA (MICROORGANISMS); BURKHOLDERIA CEPACIA COMPLEX; ESCHERICHIA COLI; HOMO SAPIENS; INQUILINUS LIMOSUS; PONGO PYGMAEUS; PRIMATES; PSEUDOMONAS AERUGINOSA; TRACHYPITHECUS OBSCURUS;

EID: 65949101251     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2009.06707.x     Document Type: Article

References (26)

1. Brown, G.D. Gordon, S. (2001) Immune recognition. A new receptor for beta-glucans. Nature 413 : 36 37.
2. Cérantola, S., Marty, N. Montrozier, H. (1996) Structural studies of the acidic exopolysaccharide produced by a mucoid strain of Burkholderia cepacia, isolated from cystic fibrosis. Carbohydr Res 285 : 59 67. (Pubitemid 26172217)
3. Chung, J.W., Altman, E., Beveridge, T.J. Speert, D.P. (2003) Colonial morphology of Burkholderia cepacia complex genomovar III: implications in exopolysaccharide production, pilus expression, and persistence in the mouse. Infect Immun 71 : 904 909. (Pubitemid 36150786)
4. Conway, B.D., Chu, K.K., Bylund, J., Altman, E. Speert, D.P. (2004) Production of exopolysaccharide by Burkholderia cenocepacia results in altered cell-surface interactions and altered bacterial clearance in mice. J Infect Dis 190 : 957 966. (Pubitemid 39120973)
5. Deretic, V., Govan, J.R., Konyecsni, W.M. Martin, D.W. (1990) Mucoid Pseudomonas aeruginosa in cystic fibrosis: mutations in the muc loci affect transcription of the algR and algD genes in response to environmental stimuli. Mol Microbiol 4 : 189 196. (Pubitemid 20080674)
6. Dürr, U.H., Sudheendra, U.S. Ramamoorthy, A. (2006) LL-37, the only human member of the cathelicidin family of antimicrobial peptides. Biochim Biophys Acta 1758 : 1408 1425. (Pubitemid 44436081)
7. Ganz, T. Lehrer, R.I. (1998) Antimicrobial peptides of vertebrates. Curr Opin Immunol 10 : 41 44. (Pubitemid 28112077)
8. Gennaro, R., Skerlavaj, B. Romeo, D. (1989) Purification, composition, and activity of two bactenecins, antibacterial peptides of bovine neutrophils. Infect Immun 57 : 3142 3146. (Pubitemid 19240086)
9. Govan, J.R.W. Deretic, V. (1996) Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia. Microbiol Rev 60 : 539 574. (Pubitemid 26303478)
10. Herasimenka, Y., Benincasa, M., Mattiuzzo, M., Cescutti, P., Gennaro, R. Rizzo, R. (2005) Interaction of antimicrobial peptides with bacterial polysaccharides from lung pathogens. Peptides 26 : 1127 1132. (Pubitemid 40798068)
11. Herasimenka, Y., Cescutti, P., Impallomeni, G. Rizzo, R. (2007) Exopolysaccharides produced by Inquilinus limosus, a new pathogen of cystic fibrosis patients: novel structures with usual components. Carbohydr Res 342 : 2404 2415. (Pubitemid 47534198)
12. Herasimenka, Y., Cescutti, P., Sampaio Noguera, C.E., Ruggiero, J.R., Urbani, R., Impallomeni, G., et al. (2008) Macromolecular properties of cepacian in water and dimethylsuphoxide. Carbohydr Res 343 : 81 89. (Pubitemid 350251345)
13. Johansson, J., Gudmundsson, G.H., Rottenberg, M.E., Berndt, K.D. Agerberth, B. (1998) Conformation-dependent antibacterial activity of the naturally occurring human peptide LL-37. J Biol Chem 273 : 3718 3724. (Pubitemid 28109800)
14. Juban, M.M., Javadpour, M.M. Barkley, M.D. (1997) Circular dichroism studies of secondary structure of peptides. Methods Mol Biol 78 : 73 78.
15. Lagatolla, C., Skerlavaj, S., Dolzani, L., Tonin, E.A., Monti Bragadin, C., Bosco, M., et al. (2002) Microbiological characterization of Burkholderia cepacia isolates from cystic fibrosis patients: investigation of the exopolysaccharides produced. FEMS Microbiol Lett 209 : 99 106. (Pubitemid 34457989)
16. Morgera, F., Antcheva, N., Pacor, S., Quaroni, L., Berti, F., Vaccari, L. Tossi, A. (2008) Structuring and interactions of human beta-defensins 2 and 3 with model membranes. J Pept Sci 14 : 518 523.
17. Nivens, D.E., Ohman, D.E., Williams, J. Franklin, M.J. (2001) Role of alginate and its O-acetylation in formation of Pseudomonas aeruginosa microcolonies and biofilms. J Bacteriol 183 : 1047 1057. (Pubitemid 32095315)
18. Ophir, T. Gutnick, D.L. (1994) A role for exopolysaccharides in the protection of microorganisms from desiccation. Appl Environ Microbiol 60 : 740 745. (Pubitemid 24045225)
19. Pier, G.B., Coleman, F., Grout, M., Franklin, M. Ohman, D.E. (2001) Role of alginate O-acetylation in resistance of mucoid Pseudomonas aeruginosa to opsonic phagocytosis. Infect Immun 69 : 1895 1901. (Pubitemid 32187652)
20. Porcelli, F., Verardi, R., Shi, L., Henzler-Wildman, A., Ramamoorthy, A. Veglia, G. (2008) NMR structure of the cathelicidin-derived human antimicrobial peptide LL-37 in dodecylphosphocoline micelles. Biochemistry 47 : 5565 5572.
21. Reckseidler-Zenteno, S.L., DeVinney, R. Woods, D.E. (2005) The capsular polysaccharide of Burkholderia pseudomallei contributes to survival in serum by reducing complement factor C3b deposition. Infect Immun 73 : 1106 1115. (Pubitemid 40165771)
22. Theilacker, C., Coleman, F.T., Mueschenborn, S., Llosa, N., Grout, M. Pier, G.B. (2003) Construction and characterization of a Pseudomonas aeruginosa mucoid exopolysaccharide-Alginate Conjugate Vaccine. Infect Immun 71 : 3875 3884. (Pubitemid 36763514)
23. Vuong, C., Voyich, J.M., Fischer, E.R., Braughton, K.R., Whitney, A.R., DeLeo, F.R. Otto, M. (2004a) Polysaccharide intercellular adhesin (PIA) protects Staphylococcus epidermidis against major components of the human innate immune system. Cell Microbiol 6 : 269 275. (Pubitemid 38248010)
24. Vuong, C., Kocianova, S., Voyich, J.M., Yao, Y., Fischer, E.R., DeLeo, F.R. Otto, M. (2004b) A crucial role for exopolysaccharide modification in bacterial biofilm formation, immune evasion, and virulence. J Biol Chem 279 : 54881 54886. (Pubitemid 40053234)
25. Zelezetsky, I., Pontillo, A., Puzzi, L., Antcheva, N., Segat, S., Pacor, S., et al. (2006) Evolution of the primate cathelicidin. Correlation between structural variations and antimicrobial activity. J Biol Chem 281 : 19861 19871. (Pubitemid 44065759)
26. Zlosnik, J.E., Hird, T.J., Fraenkel, M.C., Moreira, L.M., Henry, D.A. Speert, D.P. (2008) Differential mucoid exopolysaccharide production by members of the Burkholderia cepacia complex. J Clin Microbiol 46 : 1470 1473.