Manganese-enhanced magnetic resonance imaging (MEMRI) of rat brain after systemic administration of MnCl2: Hippocampal signal enhancement without disruption of hippocampus-dependent behavior

Behavioural Brain Research

Volumn 216, Issue 1, 2011, Pages 293-300

  Jackson, Stewart J ^a   Hussey, Rosalind ^a,b   Jansen, Maurits A ^a   Merrifield, Gavin D ^a   Marshall, Ian ^a   MacLullich, Alasdair ^a   Yau, Joyce L W ^a   Bast, Tobias ^a,c  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Delayed matching to place task; Hippocampus; Learning and memory; Manganese; MRI; Rat; Water maze

Indexed keywords

MANGANESE CHLORIDE; WATER;

ANIMAL EXPERIMENT; ARTICLE; ATAXIA; BRAIN FUNCTION; CONTROLLED STUDY; ERYTHEMA; GROWTH CURVE; HIPPOCAMPUS; IMAGE ENHANCEMENT; LATENT PERIOD; LEARNING; MALE; MAZE TEST; MEMORY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PLACE PREFERENCE; PRIORITY JOURNAL; RAT; SENSORIMOTOR FUNCTION; SIGNAL DETECTION; TASK PERFORMANCE; WEIGHT REDUCTION;

ANALYSIS OF VARIANCE; ANIMALS; ATAXIA; BRAIN MAPPING; CHLORIDES; CONTRAST MEDIA; ERYTHEMA; HIPPOCAMPUS; IMAGE ENHANCEMENT; MAGNETIC RESONANCE IMAGING; MALE; MANGANESE; MANGANESE COMPOUNDS; MAZE LEARNING; RATS;

EID: 78149406439     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2010.08.007     Document Type: Article

References (41)

1. Silva A.C., Lee J.H., Aoki I., Koretsky A.P. Manganese-enhanced magnetic resonance imaging (MEMRI): methodological and practical considerations. NMR Biomed 2004, 17:532-543.
2. Lin Y.J., Koretsky A.P. Manganese ion enhances T1-weighted MRI during brain activation: an approach to direct imaging of brain function. Magn Reson Med 1997, 38:378-388.
3. Chen W., Tenney J., Kulkarni P., King J.A. Imaging unconditioned fear response with manganese-enhanced MRI (MEMRI). Neuroimage 2007, 37:221-229.
4. Bissig D., Berkowitz B.A. Manganese-enhanced MRI of layer-specific activity in the visual cortex from awake and free-moving rats. Neuroimage 2009, 44:627-635.
5. Chuang K.H., Lee J.H., Silva A.C., Belluscio L., Koretsky A.P. Manganese enhanced MRI reveals functional circuitry in response to odorant stimuli. Neuroimage 2009, 44:363-372.
6. Eschenko O., Canals S., Simanova I., Beyerlein M., Murayama Y., Logothetis N.K. Mapping of functional brain activity in freely behaving rats during voluntary running using manganese-enhanced MRI: implication for longitudinal studies. Neuroimage 2010, 49:2544-2555.
7. Kuo Y.T., Herlihy A.H., So P.W., Bell J.D. Manganese-enhanced magnetic resonance imaging (MEMRI) without compromise of the blood-brain barrier detects hypothalamic neuronal activity in vivo. NMR Biomed 2006, 19:1028-1034.
8. Watanabe T., Radulovic J., Boretius S., Frahm J., Michaelis T. Mapping of the habenulo-interpeduncular pathway in living mice using manganese-enhanced 3D MRI. Magn Reson Imaging 2006, 24:209-215.
9. Watanabe T., Frahm J., Michaelis T. Functional mapping of neural pathways in rodent brain in vivo using manganese-enhanced three-dimensional magnetic resonance imaging. NMR Biomed 2004, 17:554-568.
10. Yu X., Wadghiri Y.Z., Sanes D.H., Turnbull D.H. In vivo auditory brain mapping in mice with Mn-enhanced MRI. Nat Neurosci 2005, 8:961-968.
11. Andersen P.M.R., Amaral D., Bliss T., O'Keefe J. The hippocampus book 2007, Oxford University Press, Oxford.
12. Bast T. Toward an integrative perspective on hippocampal function: from the rapid encoding of experience to adaptive behavior. Rev Neurosci 2007, 18:253-281.
13. Aoki I., Wu Y.J., Silva A.C., Lynch R.M., Koretsky A.P. In vivo detection of neuroarchitecture in the rodent brain using manganese-enhanced MRI. Neuroimage 2004, 22:1046-1059.
14. Eschenko O., Canals S., Simanova I., Logothetis N.K. Behavioral, electrophysiological and histopathological consequences of systemic manganese administration in MEMRI. Magn Reson Imaging 2010, Epub ahead of print.
15. Fone K.C., Porkess M.V. Behavioural and neurochemical effects of post-weaning social isolation in rodents-relevance to developmental neuropsychiatric disorders. Neurosci Biobehav Rev 2008, 32:1087-1102.
16. Hibberd C., Yau J.L., Seckl J.R. Glucocorticoids and the ageing hippocampus. J Anat. 2000, 197(Pt 4):553-562.
17. Lodge D.J., Grace A.A. Gestational methylazoxymethanol acetate administration: a developmental disruption model of schizophrenia. Behav Brain Res 2009, 204:306-312.
18. Meyer U., Feldon J. Neural basis of psychosis-related behaviour in the infection model of schizophrenia. Behav Brain Res 2009, 204:322-334.
19. Morris R.G. Episodic-like memory in animals: psychological criteria, neural mechanisms and the value of episodic-like tasks to investigate animal models of neurodegenerative disease. Philos Trans R Soc Lond B: Biol Sci 2001, 356:1453-1465.
20. Crossgrove J., Zheng W. Manganese toxicity upon overexposure. NMR Biomed 2004, 17:544-553.
21. Bock N.A., Paiva F.F., Silva A.C. Fractionated manganese-enhanced MRI. NMR Biomed 2008, 21:473.
22. Takeda A. Manganese action in brain function. Brain Res Rev 2003, 41:79-87.
23. Guilarte T.R., Chen M.K. Manganese inhibits NMDA receptor channel function: implications to psychiatric and cognitive effects. Neurotoxicology 2007, 28:1147-1152.
24. Berkowitz B.A., Roberts R., Goebel D.J., Luan H. Noninvasive and simultaneous imaging of layer-specific retinal functional adaptation by manganese-enhanced MRI. Invest Ophthalmol Vis Sci 2006, 47:2668-2674.
25. Berkowitz B.A., Roberts R., Luan H., Bissig D., Bui B.V., Gradianu M., et al. Manganese-enhanced MRI studies of alterations of intraretinal ion demand in models of ocular injury. Invest Ophthalmol Vis Sci 2007, 48:3796-3804.
26. Steele R.J., Morris R.G.M. Delay-dependent impairment of a matching-to-place task with chronic and intrahippocampal infusion of the NMDA-antagonist D-AP 5. Hippocampus 1999, 9:118-136.
27. de Hoz L., Moser E.I., Morris R.G. Spatial learning with unilateral and bilateral hippocampal networks. Eur J Neurosci 2005, 22:745-754.
28. O'Carroll C.M., Martin S.J., Sandin J., Frenguelli B., Morris R.G.M. Dopaminergic modulation of the persistence of one-trial hippocampus-dependent memory. Learn Memory 2006, 13:760.
29. Bast T., Wilson I.A., Witter M.P., Morris R.G.M. From rapid place learning to behavioral performance: a key role for the intermediate hippocampus. PLoS Biol 2009, 7:730-746.
30. Yau J.L., Noble J., Kenyon C.J., Hibberd C., Kotelevtsev Y., Mullins J.J., et al. Lack of tissue glucocorticoid reactivation in 11beta -hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments. Proc Natl Acad Sci USA 2001, 98:4716-4721.
31. Tambalo S., Daducci A., Fiorini S., Boschi F., Mariani M., Marinone M., et al. Experimental protocol for activation-induced manganese-enhanced MRI (AIM-MRI) based on quantitative determination of Mn content in rat brain by fast T1 mapping. Magn Reson Med 2009, 62:1080-1084.
32. Spooner R.I.W., Thomson A., Hall J., Morris R.G.M., Salter S.H. The Atlantis platform: a new design and further developments of Buresova's on-demand platform for the water maze. Learn Memory 1994, 1:203-211.
33. Faul F., Erdfelder E., Lang A.G., Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 2007, 39:175-191.
34. Ahlander M., Misane I., Schott P.A., Ogren S.O. A behavioral analysis of the spatial learning deficit induced by the NMDA receptor antagonist MK-801 (dizocilpine) in the rat. Neuropsychopharmacology 1999, 21:414-426.
35. Cain D.P., Saucier D., Boon F. Testing hypotheses of spatial learning: the role of NMDA receptors and NMDA-mediated long-term potentiation. Behav Brain Res 1997, 84:179-193.
36. Morris R.G. Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-d-aspartate receptor antagonist AP5. J Neurosci 1989, 9:3040-3057.
37. Chiarandini D.J., Stefani E. Effects of manganese on the electrical and mechanical properties of frog skeletal muscle fibres. J Physiol 1973, 232:129.
38. Kasten T.P., Settle S.L., Misko T.P., Currie M.G., Nickols G.A. Manganese potentiation of nitric oxide-mediated vascular relaxation. Eur J Pharmacol 1994, 253:35-44.
39. 2: dose-dependent and temporal evolution of T1 contrast. Magn Reson Med 2005, 53:640-648.
40. Canals S., Beyerlein M., Keller A.L., Murayama Y., Logothetis N.K. Magnetic resonance imaging of cortical connectivity in vivo. Neuroimage 2008, 40:458-472.
41. Nairismagi J., Pitkanen A., Narkilahti S., Huttunen J., Kauppinen R.A., Grohn O.H. Manganese-enhanced magnetic resonance imaging of mossy fiber plasticity in vivo. Neuroimage 2006, 30:130-135.